• Journal of Microbiology and Biotechnology
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• 제17권9호
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• pp.1445-1451
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• 2007

A sensitive optical waveguide lightmode spectroscopy-based immunosensor was developed to detect vitellogenin in seawater flatfish (Paralichthys olivaceus). For this purpose, anion-exchange column chromatography with DE-52 resin was used to purify flatfish vitellogenin from flatfish serum containing vitellogenin that had been induced using an intraperitoneal $17{\beta}$-estradiol injection. The anti-flatfish vitellogenin antibody used as the biological component of the above immunosensor was prepared using the purified flatfish vitellogenin. The change in the incoupling angle according to the complexation between the flatfish vitellogenin and its antibody, immobilized over an optical grating coupler sensor chip, was measured to calculate the sensor response. The immunosensor was quite specific to flatfish vitellogenin binding, based on no sensor response in the case of bovine serum albumin immobilization. When plotted using double-logarithmic scales, the sensor responses increased linearly in flatfish vitellogenin concentrations of 0.00675-67.5 nM, with a detection limit of 0.0675 nM. The reusability during seven repetitive measurements was reasonably fair for the preliminary screening of flatfish vitellogenin.

• 한국소음진동공학회논문집
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• 제16권5호
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• pp.485-494
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• 2006

The state-of-the-art of low-noise fan design usually includes the consideration of optimal sound level and sound quality. The influential design parameters of the noise level by the centrifugal fan were selected based on the preliminary test. The centrifugal fans were designed according to the experiment plan method by specifying the selected design parameters. The experiment with these machined mock-up's of centrifugal impellers suggested the major design parameters among many, having impacts upon the indices of sound quality (e.g. loudness, sharpness, roughness and fluctuation strength) at the same operation point. With the response surface method, the major design parameters selected thereafter were analyzed to estimate each contribution upon the sound quality of the centrifugal fan, and the optimal values were drawn by the consideration of the sound quality levels and their regression equations. In addition, the validity of the regression equations was numerically verified by means of the coefficient of determination. Furthermore, the mechanism by which the centrifugal fan impeller influences the determinants of its sound quality was suggested.

• 한국주거학회:학술대회논문집
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• 한국주거학회 2008년도 춘계학술발표대회 논문집
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• pp.382-385
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• 2008

The purpose of this study is to analyse design characteristics of the boutique hotel guestrooms to formalize their internal design concepts, and to evaluate the emotional response to these concepts, focusing on the response of consumers to the current trend of designs. It seems to be important, therefore, that this study are able to provide basic information necessary to establish a successful design strategy from the viewpoint of design marketing. This study was carried out with the guestrooms of 'O' Hotel, located at Paju, Gyeonggi-do Province, Korea, that is considered to fully introduce the concepts of 'Boutique Hotel.' A preliminary survey was performed by taking pictures and visiting the field from the 17th to 19th day of January 2008. Based on its results, a questionnaire survey as a major survey was conducted using a slide show according to Semantic Differential Scale on March 5, 2008. The collected data was evaluated by 50 students who majored in interior architectural design at D college, and was analysed using the SPSS Package

• Restorative Dentistry and Endodontics
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• 제38권4호
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• pp.227-233
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• 2013

Objectives: The purpose of the study was to evaluate human dental pulp response to pulpotomy with calcium hydroxide (CH), mineral trioxide aggregate (MTA), and calcium enriched mixture (CEM) cement. Materials and Methods: A total of nine erupted third molars were randomly assigned to each pulpotomy group. The same clinician performed full pulpotomies and coronal restorations. The patients were followed clinically for six months; the teeth were then extracted and prepared for histological assessments. The samples were blindly assessed by an independent observer for pulp vitality, pulp inflammation, and calcified bridge formation. Results: All patients were free of clinical signs/symptoms of pulpal/periradicular diseases during the follow up period. In CH group, one tooth had necrotic radicular pulp; other two teeth in this group had vital uninflamed pulps with complete dentinal bridge formation. In CEM cement and MTA groups all teeth had vital uninflamed radicular pulps. A complete dentinal bridge was formed beneath CEM cement and MTA in all roots. Odontoblast-like cells were present beneath CEM cement and MTA in all samples. Conclusions: This study revealed that CEM cement and MTA were reliable endodontic biomaterials in full pulpotomy treatment. In contrast, the human dental pulp response to CH might be unpredictable.

• 한국해양공학회지
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• 제15권1호
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• pp.19-25
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• 2001

Unlike structures in the air, the vibration analysis of a submerged or floating structure such as offshore structures or ships is possible only when the fluid-structure interaction is understood, as the whole or part of the structure is in contact with water. This paper introduces two methods to find natural frequency in consideration of fluid-structure interaction, direct coupled vibration analysis and fluid-structure modal coupled vibration analysis. The purpose of this study is to analyze the vibration characteristic of a submerged vehicle to obtain the anti-vibration design data, which could be used in the preliminary design stage. The underwater pressure hull of submerged vehicle is used as the model of this study. The F.E.M. model is meshed by shell and beam elements. Also, considering the inner hull weight, the mass element is distributed in the direction of hull length. Numerical calculations are accomplished by using the commercial B.E.M. code. The characteristics of natural frequency, mode shape and frequency-displacement response are analyzed.

• International Journal of Industrial Entomology and Biomaterials
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• 제3권2호
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• pp.169-175
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• 2001

A synthetic juvenoid, R394 (Ethyl 9-cyclohexyl-3, 7-dimethyl-2, 4-nonadienoate) which is known to be a strong pest control agent was administered to silkworm, Bombyx mori L. in minute quantity for improving the silk yield. Based on the result of an earlier preliminary screening, three concentrations of the compound, viz., 0.1563, 0.3125, 31.25 nl/ml were prepared in the form of an emulsion and administered topically as a single dose, to separate batches of $5^{th}$ instar silkworm at 24, 48, 72 and 96 hrs to determine the required concentration and critical time of application for an economically favourable response. Two popular commercial silkworm hybrids, PM ${\times}$ NB4D2 (multivoltine${\times}$bivoltine) and KA${\times}$NB4D2 (bivoltine$\times$bivoltine) were subjected to the experiment. The medium and absolute control were maintained in parallel to compare the results. The results showed that 0.3125 nl/ml was the best concentration of the compound and 72 hrs of $5^{th}$instar was the most favourable age for its administration to get the maximum improvement in the commercial traits. The possible role of exogenous juvenoids in eliciting favourable response in silkworm which ultimately leads to improvement in the commercial traits is discussed.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2017년도 학술발표회
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• pp.248-248
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• 2017

최근 가뭄 모니터링을 위해 과거에 비하여 고해상도의, 물리적으로 기반을 두는 정보가 요구되고 있다. 기존에 주로 활용하고 있는 통계적 방법론 기반의 가뭄지수들은 지니고 있는 한계에 대해 여러 개선과정을 거치고 있으나, 기상변수로부터 지표상의 식생 관련 변수로의 전파 과정에 대한 개별 통계적 가뭄지수 간의 관계 설명이 매우 어렵다. 이와 같은 관계로, 국내 유역에서의 물리적 기반을 둔 고해상도 가뭄 판단방법에 대한 시도가 필요한 시점이다. Brown et al. (2008)은 위성기반 식생정보, 기상학적 가뭄지수, 지형학적 조건을 고려한 식생가뭄반응지수(Vegetation Drought Response Index; 이하 VegDRI)를 개발하였다. 학습자료에 대해 CART 기반의 경험적 모델을 구축하여, 격자마다 근-실시간 자료를 적용한 VegDRI를 산출하여 고해상도의 지도를 산출하는 방식을 제시하였다. VegDRI는 NCDC의 U.S. Drought Monitoring에 활용되고 있으며, NOAA의 Drought Task Force Assessment Protocol에서는 가뭄 모니터링의 기준으로 설정되어 있다. 본 연구에서는 국내에 VegDRI를 적용하고자 필요한 자료수집 및 전처리 과정을 거쳐 결과를 도출하였다. 기상청 ASOS 기상관측소에서 얻은 기상변수, MODIS 위성으로부터 추출된 정규식생지수(Normalized Difference Vegetation Index; NDVI), 지형학적 정보와 기상학적 가뭄지수(SPI, PDSI)를 기계학습으로 모델링하여 VegDRI를 산출하였다. 산출된 VegDRI 공간분포도에 대하여 기존에 활용되던 유관기관의 가뭄 판단방법과의 유사성과 차이점을 비교 검토하여 적용성을 평가하였다.

• Structural Engineering and Mechanics
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• 제51권4호
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• pp.531-546
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• 2014

In this paper the extension of a recently established energy-based pushover procedure in order to include the higher mode contributions to the seismic response of structures is presented and preliminary evaluated. The steps of the proposed methodology in its new formulation are quite similar to those of the well-known Modal Pushover Analysis. However, the determination of the properties of the 'modal' equivalent single-degree-of-freedom systems is achieved by a rationally founded energy-based concept. Firstly, the theoretical background and the assumptions of the proposed methodology are presented and briefly discussed. Secondly, the sequence of steps to be followed for its implementation along with the necessary equations is systematically presented. The accuracy of the methodology is evaluated by an extensive parametric study which shows that, in general, it provides better results compared to those produced by other similar procedures. In addition, the main shortcoming of the initial version of the methodology now seems to be mitigated to a large extent.

• Wind and Structures
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• 제18권4호
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• pp.391-422
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• 2014

The high frequency force balance (HFFB) technique provides convenient measurements of integrated forces on rigid building models in terms of base bending moments and torque and/or base shear forces. These base moments or forces are then used to approximately estimate the generalized forces of building fundamental modes with mode shape corrections. This paper presents an analysis framework for coupled dynamic response of tall buildings with HFFB technique. The empirical mode shape corrections for generalized forces with coupled mode shapes are validated using measurements of synchronous pressures on a square building surface from a wind tunnel. An alternative approach for estimating the mean and background response components directly using HFFB measurements without mode shape corrections is introduced with a discussion on higher mode contributions. The uncertainty in the mode shape corrections and its influence on predicted responses of buildings with both uncoupled and coupled modal shapes are examined. Furthermore, this paper presents a comparison of aerodynamic base moment spectra with available data sets for various tall building configurations. Finally, e-technology aspects in conjunction with HFFB technique such as web-based on-line analysis framework for buildings with uncoupled mode shapes used in NALD (NatHaz Aerodynamic Loads Database) is discussed, which facilitates the use of HFFB data for preliminary design stages of tall buildings subject to wind loads.

• 공업화학
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• 제32권5호
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• pp.574-580
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• 2021

최고 품질의 클렌징 제품 개발을 위해서 계면활성제 혼합물 조성의 최적화를 시도하였다. 사전실험을 통해 세정력, 기포형성력, 오염률에서 각각 우수한 특성을 나타내는 계면활성제 3종 sodium cocoyl alaninate (SCoA), cocamidopropyl betaine (CPB), decyl glucoside (DG)을 선정하였다. 계면활성제 혼합물의 심플렉스 중심 설계 배열에 따른 실험을 수행하고, 실험에서 얻어진 데이터를 가지고 회귀분석을 실시하였다. 통계적으로 유의미한 반응 표면 모델식을 구하고, 세 개의 반응변수의 동시 최적화 과정을 통해 계면활성제 혼합물의 최적 조성은 SCoA (0.22), CPB (0.78), DG (0.00)으로 구해졌다.