• Title/Summary/Keyword: Predicted normal value

Search Result 77, Processing Time 0.028 seconds

Prediction of Inhalation Exposure to Benzene by Activity Stage Using a Caltox Model at the Daesan Petrochemical Complex in South Korea (CalTOX 모델을 이용한 대산 석유화학단지의 활동단계에 따른 벤젠 흡입 노출평가)

  • Lee, Jinheon;Lee, Minwoo;Park, Changyong;Park, Sanghyun;Song, Youngho;Kim, Ok;Shin, Jihun
    • Journal of Environmental Health Sciences
    • /
    • v.48 no.3
    • /
    • pp.151-158
    • /
    • 2022
  • Background: Chemical emissions in the environment have rapidly increased with the accelerated industrialization taking place in recent decades. Residents of industrial complexes are concerned about the health risks posed by chemical exposure. Objectives: This study was performed to suggest modeling methods that take into account multimedia and multi-pathways in human exposure and risk assessment. Methods: The concentration of benzene emitted at industrial complexes in Daesan, South Korea and the exposure of local residents was estimated using the Caltox model. The amount of human exposure based on inhalation rate was stochastically predicted for various activity stages such as resting, normal walking, and fast walking. Results: The coefficient of determination (R2) for the CalTOX model efficiency was 0.9676 and the root-mean-square error (RMSE) was 0.0035, indicating good agreement between predictions and measurements. However, the efficiency index (EI) appeared to be a negative value at -1094.4997. This can be explained as the atmospheric concentration being calculated only from the emissions from industrial facilities in the study area. In the human exposure assessment, the higher the inhalation rate percentile value, the higher the inhalation rate and lifetime average daily dose (LADD) at each activity step. Conclusions: Prediction using the Caltox model might be appropriate for comparing with actual measurements. The LADD of females was higher ratio with an increase in inhalation rate than those of males. This finding would imply that females may be more susceptible to benzene as their inhalation rate increases.

Temperature and magnetic field dependent optical properties of superconducting $MgB_2$ thin film (초전도 $MgB_2$ 박막의 온도와 장기장의 변화에 따른 광학적 성질)

  • Jung, J. H.;Lee, H. J.;Kim, K. W.;Kim, M. W.;Noh, T. W.;Wang, Y. J.;Kang, W. N.;Jung, C. U.;Lee, Sung-Ik
    • Progress in Superconductivity
    • /
    • v.3 no.1
    • /
    • pp.31-35
    • /
    • 2001
  • We investigated the temperature and magnetic field dependent optical properties of a$ MgB_2$ thin film in the far-infrared region. In the superconducting state, i.e. 5 K, we obtained the values of superconducting gap $2\Delta$ ~ 5.2 meV and $2\Delta$ $_{k}$ $B/T_{c}$ ~1.8. Although the value of$ 2\Delta$$B/T_{c}$ was nearly half of the BCS value, the $2\Delta$ seemed to follow the temperature dependence of the BCS formula. Under the magnetic field (H), the superconducting state became suppressed. Interestingly, we found that the normal state area fraction abruptly increased at low field but slowly increased at high field. It did not follow the H-dependences predicted for a s-wave superconductor (i.e. a linear dependence) nor for a s-wave one (i.e. $H^{1}$2/ dependence). We discussed the complex gap nature of $MgB_2$ in comparison with two gap and anisotropic s-wave scenarios.ios.

  • PDF

Changes of Biogenic Amine Level during Storage and Development of New Quality Index on Silkworm Pupa (식용 번데기의 저장 중 Biogenic Amine 함량 변화와 품질지표 개발)

  • Cho, Tae-Yong;Han, Gyu-Hong;Kang, Byung-Sun;Kim, Seon-Bong
    • Journal of Food Hygiene and Safety
    • /
    • v.22 no.4
    • /
    • pp.268-272
    • /
    • 2007
  • A study on the evolution of acid value, peroxide value and biogenic amines in silkworm pupa during 7 days at different temperature of storage (-18, 25 and $35^{\circ}C$) was performed. Seven biogenic amines (putrescine, cadaverine, histamine, tyramine, spermidine, spermine and 2-phenylethylamine) were determined. Acid value in Silkworm pupa increased both during normal temperature $(25^{\circ}C)$ and room temperature $(35^{\circ}C)$ and thebiogenic amine (histamine, tyramine) content generally increased in $25^{\circ}C\;and\;35^{\circ}C$ with storage time. Significant differences were found (P<0.05) in the levels of tyramine and histamine among Silkworm pupa. The relationship of storage time and acid value of Silkworm pupa were resolved a simple linear equation, and histamine and tyramine could be predicted using this equation. Quality indices related to the contents of the major biogenic amines were calculated and they correlated well with physicochemical characteristics qualities such as acid value.

A predictive model to guide management of the overlap region between target volume and organs at risk in prostate cancer volumetric modulated arc therapy

  • Mattes, Malcolm D.;Lee, Jennifer C.;Elnaiem, Sara;Guirguis, Adel;Ikoro, N.C.;Ashamalla, Hani
    • Radiation Oncology Journal
    • /
    • v.32 no.1
    • /
    • pp.23-30
    • /
    • 2014
  • Purpose: The goal of this study is to determine whether the magnitude of overlap between planning target volume (PTV) and rectum ($Rectum_{overlap}$) or PTV and bladder ($Bladder_{overlap}$) in prostate cancer volumetric-modulated arc therapy (VMAT) is predictive of the dose-volume relationships achieved after optimization, and to identify predictive equations and cutoff values using these overlap volumes beyond which the Quantitative Analyses of Normal Tissue Effects in the Clinic (QUANTEC) dose-volume constraints are unlikely to be met. Materials and Methods: Fifty-seven patients with prostate cancer underwent VMAT planning using identical optimization conditions and normalization. The PTV (for the 50.4 Gy primary plan and 30.6 Gy boost plan) included 5 to 10 mm margins around the prostate and seminal vesicles. Pearson correlations, linear regression analyses, and receiver operating characteristic (ROC) curves were used to correlate the percentage overlap with dose-volume parameters. Results: The percentage $Rectum_{overlap}$ and $Bladder_{overlap}$ correlated with sparing of that organ but minimally impacted other dose-volume parameters, predicted the primary plan rectum $V_{45}$ and bladder $V_{50}$ with $R^2$ = 0.78 and $R^2$ = 0.83, respectively, and predicted the boost plan rectum $V_{30}$ and bladder $V_{30}$ with $R^2$ = 0.53 and $R^2$ = 0.81, respectively. The optimal cutoff value of boost $Rectum_{overlap}$ to predict rectum $V_{75}$ >15% was 3.5% (sensitivity 100%, specificity 94%, p < 0.01), and the optimal cutoff value of boost $Bladder_{overlap}$ to predict bladder $V_{80}$ >10% was 5.0% (sensitivity 83%, specificity 100%, p < 0.01). Conclusion: The degree of overlap between PTV and bladder or rectum can be used to accurately guide physicians on the use of interventions to limit the extent of the overlap region prior to optimization.

Factors Associated with Lung Function Recovery at the First Year after Lung Transplantation

  • Yoon, Bo Ra;Park, Ji Eun;Kim, Chi Young;Park, Moo Suk;Kim, Young Sam;Chung, Kyung Soo;Song, Joo Han;Paik, Hyo-Chae;Lee, Jin Gu;Kim, Song Yee
    • Yonsei Medical Journal
    • /
    • v.59 no.9
    • /
    • pp.1088-1095
    • /
    • 2018
  • Purpose: Post-operative pulmonary function is an important prognostic factor for lung transplantation. The purpose of this study was to identify factors affecting recovery of forced expiratory volume in 1 second (FEV1) at the first year after lung transplantation. Materials and Methods: We retrospectively reviewed the medical records of lung transplantation patients between October 2012 and June 2016. Patients who survived for longer than one year and who underwent pulmonary function test at the first year of lung transplantation were enrolled. Patients were divided into two groups according to whether they recovered to a normal range of FEV1 (FEV1 ${\geq}80%$ of predicted value vs. <80%). We compared the two groups and analyzed factors associated with lung function recovery. Results: Fifty-eight patients were enrolled in this study: 28 patients (48%) recovered to a FEV1 ${\geq}80%$ of the predicted value, whereas 30 patients (52%) did not. Younger recipients [odds ratio (OR), 0.92; 95% confidence interval (CI), 0.87-0.98; p=0.010], longer duration of mechanical ventilator use after surgery (OR, 1.14; 95% CI, 1.03-1.26; p=0.015), and high-grade primary graft dysfunction (OR, 8.08; 95% CI, 1.67-39.18; p=0.009) were identified as independent risk factors associated with a lack of full recovery of lung function at 1 year after lung transplantation. Conclusion: Immediate postoperative status may be associated with recovery of lung function after lung transplantation.

Prediction of Wind Damage Risk based on Estimation of Probability Distribution of Daily Maximum Wind Speed (일 최대풍속의 추정확률분포에 의한 농작물 강풍 피해 위험도 판정 방법)

  • Kim, Soo-ock
    • Korean Journal of Agricultural and Forest Meteorology
    • /
    • v.19 no.3
    • /
    • pp.130-139
    • /
    • 2017
  • The crop damage caused by strong wind was predicted using the wind speed data available from Korean Meteorological Administration (KMA). Wind speed data measured at 19 automatic weather stations in 2012 were compared with wind data available from the KMA's digital forecast. Linear regression equations were derived using the maximum value of wind speed measurements for the three-hour period prior to a given hour and the digital forecasts at the three-hour interval. Estimates of daily maximum wind speed were obtained from the regression equation finding the greatest value among the maximum wind speed at the three-hour interval. The estimation error for the daily maximum wind speed was expressed using normal distribution and Weibull distribution probability density function. The daily maximum wind speed was compared with the critical wind speed that could cause crop damage to determine the level of stages for wind damage, e.g., "watch" or "warning." Spatial interpolation of the regression coefficient for the maximum wind speed, the standard deviation of the estimation error at the automated weather stations, the parameters of Weibull distribution was performed. These interpolated values at the four synoptic weather stations including Suncheon, Namwon, Imsil, and Jangsu were used to estimate the daily maximum wind speed in 2012. The wind damage risk was determined using the critical wind speed of 10m/s under the assumption that the fruit of a pear variety Mansamgil would begin to drop at 10 m/s. The results indicated that the Weibull distribution was more effective than the normal distribution for the estimation error probability distribution for assessing wind damage risk.

Peak Expiratory Flow(PEF) Measured by Peak Flow Meter and Correlation Between PEF and Other Ventilatory Parameters in Healthy Children (정상 소아에서 최고호기유량계(peak flow meter)로 측정한 최고호기유량(PEF)와 기타 환기기능검사와의 상관관계)

  • Oak, Chul-Ho;Sohn, Kai-Hag;Park, Ki-Ryong;Cho, Hyun-Myung;Jang, Tae-Won;Jung, Maan-Hong
    • Tuberculosis and Respiratory Diseases
    • /
    • v.51 no.3
    • /
    • pp.248-259
    • /
    • 2001
  • Background : In diagnosis or monitor of the airway obstruction in bronchial asthma, the measurement of $FEV_1$ in the standard method because of its reproducibility and accuracy. But the measurement of peak expiratory flow(PEF) by peak flow meter is much simpler and easier than that of $FEV_1$ especially in children. Yet there have been still no data of the predicted normal values of PEF measured by peak flow meter in Korean children. This study was conducted to provide equations to predict the normal value of PEF and correlation between PEF and $FEV_1$ in healthy children. Method : PEF was measured by MiniWright peak flow meter, and the forced expiratory volume and the maximum expiratory flow volume curves were measured by Microspiro HI 501(Chest Co.) in 346 healthy children(age:5-16 years, 194 boys and 152 girls) without any respiratory symptoms during 2 weeks before the study. The regression equations for various ventilatory parameters according to age and/or height, and the regression equations of $FEV_1$ by PEF were derived. Results : 1. The regression equation for PEF(L/min) was: $12.6{\times}$age(year)+$3.4{\times}$height(cm)-263($R^2=0.85$) in boys, and $6{\times}$age(year)+$3.9{\times}$height(cm)-293($R^2=0.82$) in girls. 2. The value of FEFmax(L/sec) derived from the maximum expiratory flow volume curves was multiplied by 60 to compare with PEF(L/min), and PEF was faster by 125 L/min in boys and 118 L/min in girls, respectively. 3. The regression equation for $FEV_1$(ml) by PEF(L/min) was:$7{\times}$PEF-550($R^2=0.82$) in boys, and $5.8{\times}$PEF-146 ($R^2=0.81$) in girls, respectively. Conclusion : This study provides regression equations predicting the normal values of PEF by age and/or height in children. And the equations for $FEV_1$, a gold standard of ventilatory function, was predicted by PEF. So, in taking care of children with airway obstruction, PEF measured by the peak flow meter can provide useful information.

  • PDF

GLCM Algorithm Image Analysis of Nonalcoholic Fatty Liver and Focal Fat Sparing Zone in the Ultrasonography (초음파검사에서 비알콜성 지방간과 국소지방회피영역에 대한 GLCM Algorithm 영상분석)

  • Cho, Jin-Young;Ye, Soo-Young
    • Journal of radiological science and technology
    • /
    • v.40 no.2
    • /
    • pp.205-211
    • /
    • 2017
  • There is a need for aggressive diagnosis and treatment in middle-aged and high-risk individuals who are more likely to progress from nonalcoholic fatty liver to hepatitis. In this study, nonalcoholic fatty liver was divided into severe, moderate, and severe, and classified by quantitative method using computer analysis of GLCM algorithm. The purpose of this study was to evaluate the characteristics of ultrasound images in the local fat avoidance region. Normal, mild, moderate, severe fatty liver, and focal fat sparing area, 80 cases, respectively. Among the parameters of the GLCM algorithm, the values of the Autocorrelation, Square of the deviation, Sum of averages and Sum of variances with high recognition rate of the liver ultrasound image were calculated. The average recognition rate of the GLCM algorithm was 97.5%. The result of local fat avoidance image analysis showed the most similar value to the normal parenchyma. Ultrasonography can be easily accessed by primary screening, but there may be differences in the accuracy of the test method or the correspondence of results depending on proficiency. GLCM algorithm was applied to quantitatively classify the degree of fatty liver. Local fat avoidance region was similar to normal parenchyma, so it could be predicted to be homogeneous liver parenchyma without fat deposition. We believe that GLCM computer image analysis will provide important information for differentiating not only fatty liver but also other lesions.

Toxic Effect of Zinc Undecylenate on the Embryogenesis of Sea Urchins Hemicentrotus pulcherrimus and Mesocentrotus nudus (Zinc Undecylenate가 말똥성게(Hemicentrotus pulcherrimus)와 둥근성게(Mesocentrotus nudus)의 배아발생에 미치는 독성 영향)

  • Choi, Hoon;Park, Yun-Ho;Lee, Ju-Wook;Lee, Seung-Min;Choi, Youn-Seok;Hwang, Un-Ki
    • Journal of Marine Life Science
    • /
    • v.5 no.2
    • /
    • pp.43-50
    • /
    • 2020
  • The aim of this study is toxicity assessment using two types of sea urchins (H. pulcherrimus, M. nudus) that can representative primary consumers in potential coastal environments pollutants, Zinc undecylenate (ZU), which is used for various purposes, such as pharmaceutical agents and anti-bacterial and anti-fungi. The Fertilization rate and normal embryogenesis rate of H. pulcherrimus and M. nudus were concentration-dependent decreased. Besides, EC50 of fertilization rate with H. pulcherrimus and M. nudus were 11.27 mgl-1 and 1.48 mgl-1, and EC50 of normal embryogenesis were 0.94 mgl-1 and 3.78 mgl-1. NOEC of normal embryogenesis were 0.20 and 0.78 mgl-1, respectively. In addition, to find the safety criteria of the ZU on the marine environment. PNEC value was 0.0094 mgl-1, calculated using the toxicity values of two species of sea urchin derived from this study and the acute toxicity results of the coastal area through literature research. The above results will be used as basic data for establishing environmental protection strategies for marine environmental pollutants.

Forecasting Monthly Agricultural Reservoir Storage and Estimation of Reservoir Drought Index (RDI) Using Meteorological Data Based Multiple Linear Regression Analysis (기상자료기반 다중선형회귀분석에 의한 농업용 저수지 월단위 저수율 예측 및 저수지 가뭄지수(RDI) 추정)

  • LEE, Ji-Wan;KIM, Jin-Uk;JUNG, Chung-Gil;KIM, Seong-Joon
    • Journal of the Korean Association of Geographic Information Studies
    • /
    • v.21 no.3
    • /
    • pp.19-34
    • /
    • 2018
  • The purpose of this study is to estimate monthly agricultural reservoir storage with multiple linear regression model(MLRM) based on reservoir storage and meteorological data. The regression model was developed using 15 years(2002 to 2016) of 3,067 reservoirs by KRC(Korea Rural Community) and 63 meteorological stations by KMA (Korean Meteorological Administration), and the MLRM showed the determination coefficient($R^2$) of 0.51~0.95. The MLRM was applied to 9 selected reservoirs among the whole reservoirs and validated with $R^2$ of 0.44~0.81. The ROC(Receiver Operating Characteristics) analysis of Reservoir Drought Index(RDI) classified by comparing the present reservoir storage with normal year(1976~2005 average) reservoir storage showed average value of 0.64 for 2 years(2015~2016) with the highest value of 0.70 for winter period, lowest value of 0.58 for summer period. If 1 to 3 months weather forecasting data such as Glosea5 produced by KMA are applied, the predicted monthly reservoir storage from the MLRM can be a useful information for agricultural drought pre-preparation.