• Journal of the Society of Naval Architects of Korea
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• v.42 no.6 s.144
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• pp.637-643
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• 2005

A new novel Whipping Factor is proposed as a measure of the ship damage potential due to an underwater explosion bubble pulse. The factor was derived from the relationships among the charge weight, its depth and the fluid acceleration due to pulsating gas bubble. From the whipping response analyses for three uniform Timoshenko beams with similar characteristics of real naval surface ships, we have confirmed the maximum bending moment responses of beams due to whipping are almost same if the applied whipping factor is constant regardless of the charge weights and depths, which could validate the proposed whipping factor.

• Earthquakes and Structures
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• v.2 no.1
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• pp.1-24
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• 2011

During very strong earthquakes, seismically isolated buildings may experience large horizontal relative displacements, which may lead to poundings if an insufficiently wide clearance is provided around the building. This paper investigates, through numerical simulations, the effectiveness of using rubber bumpers, which could be attached at locations where it is likely to have impacts, in order to act as shock-absorbers. For the simulation of the dynamic behavior of such rubber bumpers during impacts, a nonlinear force-based impact model, which takes into account the finite thickness of the rubber bumpers, has been developed. Subsequently, a series of parametric analyses are performed to assess the effect of the gap size, the earthquake characteristics and the thickness, compressive capacity and damping of the bumpers. The stiffness of the moat wall is also parametrically considered during poundings of a seismically isolated building, as another potential mitigation measure for poundings of seismically isolated buildings.

• Proceedings of the Korean Institute of Surface Engineering Conference
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• 2015.05a
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• pp.50-50
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• 2015

양극산화를 통하여 타이타늄 산화물 나노튜뷰를 제조하고 전기화학적 촉매능을 향상시키기 위하여 다양한 방법의 촉매 도핑방법을 소개한다. 특히, 단일(single step) 양극산화법과 전기충격법(potential shock)를 통한 촉매도핑법을 비교하며 장횡비(high aspect ratio)가 높은 나노튜뷰에 균일하고 효율적인 촉매도핑법 및 도핑된 나노튜뷰를 활용한 물분해 실험결과를 소개한다.

• Korean Journal of Applied Biomechanics
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• v.25 no.3
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• pp.283-291
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• 2015

Objective : The purpose of this study was to determine the differences in the head and tibial acceleration signal magnitudes, and their powers and shock attenuations between flat-footed and normal-footed running. Methods : Ten flat-footed and ten normal-footed subjects ran barefoot on a treadmill with a force plate at 3.22m/s averaged from their preferred running speed using heel-toe running pattern while the head and tibial acceleration in the vertical axis data was collected. The accelerometers were sampled at 2000 Hz and voltage was set at 100 mv, respectively. The peak magnitudes of the head and tibial acceleration signals in time domain were calculated. The power spectral density(PSD) of each signal in the frequency domain was also calculated. In addition to that, shock attenuation was calculated by a transfer function of the head PSD relative to the tibia PSD. A one-way analysis of variance was used to determine the difference in time and frequency domain acceleration variables between the flat-footed and normal-footed groups running. Results : Peaks of the head and tibial acceleration signals were significantly greater during flat-footed group running than normal-footed group running(p<.05). PSDs of the tibial acceleration signal in the lower and higher frequency range were significantly greater during flat-footed running(p<.05), but PSDs of the head acceleration signal were not statistically different between the two groups. Flat-footed group running resulted in significantly greater shock attenuation for the higher frequency ranges compared with normal-footed group running(p<.05). Conclusion : The difference in impact shock magnitude and frequency content between flat-footed and normal-footed group during running suggested that the body had different ability to control impact shock from acceleration. It might be conjectured that flat-footed running was more vulnerable to potential injury than normal-footed running from an impact shock point of view.

• Explosives and Blasting
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• v.26 no.1
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• pp.15-21
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• 2008

In case of estimating the shocking vibration during the blasting demolitions, the weight and falling height of the structure, that is a potential energy, had been considered. But, this study presented a new equation which used the impulse concerning a falling weight instead of potential energy as a method of predicting the shock vibration. In this experiment, the data of the impulse were compared with the data of the potential energy by performing the free-fall, and all data were comparatively analyzed by the regression analysis method. Also, the method of the superposition theory, which is calculated by the diminution ratio according to distance, the free-fall difference according to height, and the time giving the shock to the ground according to the breakdown pattern, was compared with the previous vibration data occurring from the blasting demolitions in the same conditions. As a result, this study suggests that the impulse and the method of superposition theory be applied as a method of predicting the shocking vibration. Therefore, these results could be expected to estimate the shocking vibration more accurately than the previous method.

• Parasites, Hosts and Diseases
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• v.53 no.6
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• pp.665-673
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• 2015

After invasion of red blood cells, malaria matures within the cell by degrading hemoglobin avidly. For enormous protein breakdown in trophozoite stage, many efficient and ordered proteolysis networks have been postulated and exploited. In this study, a potential interaction of a 60-kDa Plasmodium falciparum (Pf)-heat shock protein (Hsp60) and Pf-calpain, a cysteine protease, was explored. Pf-infected RBC was isolated and the endogenous Pf-Hsp60 and Pf-calpain were determined by western blot analysis and similar antigenicity of GroEL and Pf-Hsp60 was determined with anti-Pf-Hsp60. Potential interaction of Pf-calpain and Pf-Hsp60 was determined by immunoprecipitation and immunofluorescence assay. Mizoribine, a well-known inhibitor of Hsp60, attenuated both Pf-calpain enzyme activity as well as P. falciparum growth. The presented data suggest that the Pf-Hsp60 may function on Pf-calpain in a part of networks during malaria growth.

• Journal of the Korean Magnetic Resonance Society
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• v.23 no.1
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• pp.26-32
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• 2019

${\alpha}B$-crystallin (${\alpha}BC$) is a member of a small heat-shock protein (sHSP) superfamily and plays a predominant role in cellular protein homeostasis network by rescuing misfolded proteins from irreversible aggregation. ${\alpha}BC$ assembles into dynamic and polydisperse high molecular weight complexes containing 12 to 48 monomers; this variable stereochemistry of ${\alpha}BC$ has been linked to quaternary subunit exchange and its chaperone activity. The chaperone activity of ${\alpha}BC$ poses great potential as therapeutic agents for various neurodegenerative diseases. In this mini-review, we briefly outline the recent advancement in structural characterization of ${\alpha}BCs$ and its potential role to inhibit protein misfolding and aggregation in various human diseases. In particular, nuclear magnetic resonance (NMR) spectroscopy and its complimentary techniques have contributed much to elucidate highly-dynamic nature of ${\alpha}BCs$, among which notable advancements are discussed in detail. We highlight the importance of resolving the structural details of various ${\alpha}BC$ oligomers, their quaternary dynamics, and structural heterogeneity.

• Journal of The Korean Astronomical Society
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• v.37 no.5
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• pp.483-491
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• 2004

Clusters of galaxies are storage rooms of cosmic rays. They confine the hadronic component of cosmic rays over cosmological time scales due to diffusion, and the electron component due to energy losses. Hadronic cosmic rays can be accelerated during the process of structure formation, because of the supersonic motion of gas in the potential wells created by dark matter. At the shock waves that result from this motion, charged particles can be energized through the first order Fermi process. After discussing the most important evidences for non-thermal phenomena in large scale structures, we describe in some detail the main issues related to the acceleration of particles at these shock waves, emphasizing the possible role of the dynamical backreaction of the accelerated particles on the plasmas involved.

• The Transactions of the Korean Institute of Electrical Engineers P
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• v.57 no.2
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• pp.84-90
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• 2008

This paper describes the investigation into the actual condition of electrical equipments installation and management for establishing the countermeasures against the electric shock in submerged underground. The investigation was carried out for 27 underground premises in conurbation including Seoul, and potential of the exposed electrical equipments negatively affecting on human safety when disaster occurs was measured. The objects to which measurement was carried out were as follows; electrical source; advertising lighting; power equipment. As a result, it was confirmed that potentials more than 230[V] were induced in some equipments. In addition, the electrical equipments installed in most conventional underground premises were left unmanaged.

• The Plant Pathology Journal
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• v.31 no.4
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• pp.323-333
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• 2015

As sessile organisms, plants are exposed to persistently changing stresses and have to be able to interpret and respond to them. The stresses, drought, salinity, chemicals, cold and hot temperatures, and various pathogen attacks have interconnected effects on plants, resulting in the disruption of protein homeostasis. Maintenance of proteins in their functional native conformations and preventing aggregation of non-native proteins are important for cell survival under stress. Heat shock proteins (HSPs) functioning as molecular chaperones are the key components responsible for protein folding, assembly, translocation, and degradation under stress conditions and in many normal cellular processes. Plants respond to pathogen invasion using two different innate immune responses mediated by pattern recognition receptors (PRRs) or resistance (R) proteins. HSPs play an indispensable role as molecular chaperones in the quality control of plasma membrane-resident PRRs and intracellular R proteins against potential invaders. Here, we specifically discuss the functional involvement of cytosolic and endoplasmic reticulum (ER) HSPs/chaperones in plant immunity to obtain an integrated understanding of the immune responses in plant cells.