• Title/Summary/Keyword: Possibility Measure

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Whitening Activity of Sambucus Sieboldiana Var. Pendula (Nakai) Extract (말오줌나무 추출물의 미백활성 검증)

  • Yoo, Dan-Hee;Kim, Jin-Tae;Oh, Min-Jeong;Yeom, Hyeon-Ji;Lee, Jin-Young
    • Journal of Life Science
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    • v.29 no.3
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    • pp.279-286
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    • 2019
  • This study evaluated the anti-oxidant and whitening effects of a 70% ethanol extract of the Sambucus sieboldiana var. pendula (Nakai) (SS). At $1,000{\mu}g/ml$ concentration, the electron donating ability of this SS extract was found to be 86.21% and the ABTS+ radical scavenging ability was 97.9%. In terms of whitening activity, the tyrosinase inhibitory effect of the extract was 37%, also at $1,000{\mu}g/ml$ concentration. To explore the extractefftoxicity to B16F10 melanoma cells, a 3-[4,5-dimethyl-thiazol-2-yl]-2,5-diphenyl-tetrazoliumbromide assay was performed. Results showed 90% or more cells remained viable at $100{\mu}g/ml$ concentration. A Western blot of the SS extract was used to measure microphthalmia-associated transcription factor (MITF), tyrosinase-related protein-1 (TRP-1), tyrosinase relate protein-2 (TRP-2), and the tyrosinase protein expression inhibitory effect at 25, 50, $100{\mu}g/ml$ concentrations; ${\beta}-actin$ was used as a positive control. Consequently, the MITF, TRP-1, TRP-2, and the tyrosinase protein expression inhibitory effect were seen to decrease by 34.5%, 45.6%, 58.4%, and 79.6%, respectively, at $100{\mu}g/ml$ concentration. These were also then measured by reverse transcription-polymerase chain reaction at 25, 50, $100{\mu}g/ml$ concentrations with GAPDH as a positive control. As a result, the SS extract was seen to decrease MITF, TRP-1, TRP-2, and the tyrosinase protein expression inhibitory effect by 85.4%, 67.5%, 85.2%, 67.1%, respectively at the $100{\mu}g/ml$ concentration. We therefore confirmed the possibility of Sambucus sieboldiana var. pendula (Nakai) extract as a whitening material.

Study on Pile Cloth Rugs Produced after the Late Joseon Period (조선 말기 이후 첨모직 깔개에 관한 연구)

  • Park, Yoon-Mee;Oh, Joon Suk
    • Korean Journal of Heritage: History & Science
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    • v.51 no.4
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    • pp.84-107
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    • 2018
  • Cheommojik is a pile cloth, a type of textile whose surface is covered with short piles. The term chaedam was used during the late Joseon dynasty to refer to pile cloth rugs, while the terms yoongjeon, dantong and yangtanja were used in the early twentieth century. Various documents, newspaper articles and photographs confirm that pile cloth rugs were used by the general public as well as the royal family from the late Joseon dynasty onward, and that there were domestic manufacturers of such rugs at that time. This study investigated six pile cloth rugs that were produced after the late Joseon dynasty, five of which feature Persian knots made of cut pile, the other being made with the loop pile method. The cut pile rugs are rectangular in shape and measure between 72-98cm by 150-156cm; and they are decorated in the middle with patterns of butterfly, deer, and tiger or the ten longevity symbols, and along the edges with patterns composed of 卍 symbols. The ground warp of all six rugs are made from cotton yarn, while the ground weft is made of cotton yarn on three pieces, wool on one piece and cotton and viscose rayon. The ground weft yarn from four pieces are Z-twist yarn made with two or more S-twist cotton yarn. Four to six colors were used for the pile weft, all being natural colors except for red. Two or more S- or Z-twist yarn were twisted together in the opposite twist for the pile weft, with the thickness determining the number of threads used. Six or more weft threads were used to make the start and end points of the rug; and the ground warp ends were arranged by tying every four of them together. For the left and right edges, three or more threads were wrapped together into a round stick-like form, and the second and third inner ground warps from the edges were stitched on to the wrapped edge. For the loop pile, loops were made in the direction of the warp; the ground warp and the ground weft may have been made with cotton, the pile warp with wool yarn. An analysis of the components of three rugs was conducted to determine which types of animal hair were used for the pile weft. Despite some inconclusive results, it was revealed that goat hair and fat-tailed sheep hair were used, raising the possibility that various kinds of animal fur were used in the production of pile cloth rugs. The six rugs examined in this study are estimated to have been made between the late 1800s and the early 1900s. Although the manufacturer of the rugs cannot be confirmed, we concluded that the rugs were produced in Korea after referring to the documentation of the domestic production of pile cloth rugs during the aforementioned period and the form and placements of the patterns on the rugs.

Estimation of the Three-dimensional Vegetation Landscape of the Donhwamun Gate Area in Changdeokgung Palace through the Rubber Sheeting Transformation of (<동궐도(東闕圖)>의 러버쉬팅변환을 통한 창덕궁 돈화문 지역의 입체적 식생 경관 추정)

  • Lee, Jae-Yong
    • Korean Journal of Heritage: History & Science
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    • v.51 no.2
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    • pp.138-153
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    • 2018
  • The purpose of this study was to analyze , which was made in the late Joseon Dynasty to specify the vegetation landscape of the Donhwamun Gate area in Changdeokgung Palace. The study results can be summarized as below. First, based on "Jieziyuan Huazhuan(芥子園畵傳)", the introductory book of tree expression delivered from China in the 17th century, allowed the classification criteria of the trees described in the picture to be established and helped identify their types. As a result of the classification, there were 10 species and 50 trees in the Donhwamun Gate area of . Second, it was possible to measure the real size of the trees described in the picture through the elevated drawing scale of . The height of the trees ranged from a minimum of 4.37 m to a maximum of 22.37 m. According to the measurement results, compared to the old trees currently living in Changdeokgung Palace, the trees described in the picture were found to be produced in almost actual size without exaggeration. Thus, the measured height of the trees turned out to be appropriate as baseline data for reproduction of the vegetation landscape. Third, through the Rubber Sheeting Transformation of , it was possible to make a ground plan for the planting of on the current digital topographic map. In particular, as the transformed area of was departmentalized and control points were added, the precision of transformation improved. It was possible to grasp the changed position of planting as well as the change in planting density through a ground plan of planting of . Lastly, it was possible to produce a three-dimensional vegetation landscape model by using the information of the shape of the trees and the ground plan for the planting of . Based on the three-dimensional model, it was easy to examine the characteristics of the three-dimensional view of the current vegetation via the view axis, skyline, and openness to and cover from the adjacent regions at the level of the eyes. This study is differentiated from others in that it verified the realism of and suggested the possibility of ascertaining the original form of the vegetation landscape described in the painting.

Evaluation of sleep quality and stress response in patients requiring dental prosthetic treatment (치과보철치료를 요하는 환자에서의 수면질과 스트레스 반응 평가)

  • Jeon, Hye-Mi;Jung, Kyoung-Hwa;Choi, Na-Rae;Song, Jae-Min;Lee, So-Hyoun;Kim, So-Yeun
    • The Journal of Korean Academy of Prosthodontics
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    • v.59 no.2
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    • pp.181-189
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    • 2021
  • Purpose: The purpose of this study is to investigate the stress response and sleep state of the new patients who visit the hospital for prosthodontic treatment due to tooth loss to make reference to further treatment direction. Materials and methods: Examinations, consultations, and surveys were conducted on 236 patients (94 males, 142 females, and 24-86 years old), who newly registered at the department of prosthodontics at Pusan national university hospital, for 2 years from 2018. The number of remaining teeth, edentulous arch, possibility of mastication, and future prosthetic treatment directions were recorded. The visual analogue scale (VAS), stress response inventory (SRI) and Insomnia severity index (ISI) were used as tools to measure patient's subjective discomfort, stress response, and sleep status. Results: Among the entire prosthodontic patient group, the average value of 'fatigue' was significantly higher among the 7 items of SRI, and the value of 'aggression' was significantly lower (P<.001). There are a significant difference between the edentulous and full dentition in the oral discomfort value measured by VAS (P=.004). In cases where less than 20 teeth remain, mastication is impossible, and patients who are planning treatment with removable prostheses, VAS value and 'depression' and 'fatigue' values in SRI were higher than those in the reverse case (P<.05). The patients showed severe level in VAS value have high value of 'tension', 'somatization', 'depression', 'fatigue'and 'frustration'in SRI than non-serious patients (P<.05). Clinical insomnia occurred in 11.4% of all patients, and women had significantly lower sleep quality than men (P=.044). Patients with insomnia showed significantly higher scores on the VAS value and all 7 SRI items than those of normal sleepers (P<.05). Conclusion: The new prosthetics had high 'fatigue' value among the 7 items of SRI. The oral condition, number of residual teeth and mastication function and clinical insomnia affected oral discomfort and the stress response.

Evaluation of the possibility of clinical application by surface dose measurement of ViewRay in MFW treatment (MFW 치료 시 ViewRay의 표면선량 측정에 따른 임상 적용 가능성 평가)

  • Sun, Geo Jun;Son, Sang Jun;Lee, Yang Hoon;Lee, Je Hee
    • The Journal of Korean Society for Radiation Therapy
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    • v.30 no.1_2
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    • pp.169-176
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    • 2018
  • Purpose : The purpose of this study is to evaluate clinical applicability of Co-60 ViewRay treatment plan to increase the skin dose in case of high skin dose is required such as Malignant Fungating Wound By measuring the presence / absence of Bolus application and skin dose by the treatment device and comparing it Materials and Methods : Nine inner measuring points of 2.5 cm lattice arrangement and all 13 measuring points including upper and lower left and right measuring points touching the chest and skin were marked. After CT was taken, each treatment plan was formulated through Eclipse and ViewRay-TPS, and a Fixed beam-IMRT treatment plan was formulated so that the left chest V2Gy=95 % is delivered. Before measurement QED detector was calibrated and the QED detector was positioned at the 13 measurement points displayed on Phantom and surface dose of each treatment planner was measured using 5 mm Bolus application using True-beam and View-ray before and after, measure three times and compare each before applying 5 mm Bolus. Results : The surface dose of the Co-60 ViewRay and the linear accelerator appeared at $76.8%{\pm}5.2%$ vs. $67.3{\pm}%7.5%$ and the surface dose after application of 5 mm Bolus was $87.6%{\pm}8.9%$ vs. $80.3%{\pm}10.2%$ It was measured at 10.2 % (p<0.001). Conclusion : As a result of the surface dose measurement of each treatment instrument, Co-60 ViewRay confirmed that the surface dose reached 95.6 % of 6 MV Linac with conventional 5 mm bolus, despite not using Bolus (p<0.001). Also, by utilizing magnetic resonance images for each treatment, it is possible to observe the change in the treatment site without the problem of exposure, it is easy to formulate an adaptive treatment plan and it is easy to secure the skin dose, so the size In the case of Malignant Fungating Wound patients who need fast skin changes and need high skin doses, Co-60 ViewRay is considered to be more useful than linear accelerators.

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Evaluation of Physical Properties of Liposome Essences as Customized Cosmetic Bases and Evaluation of Satisfaction According to Skin Type (맞춤형화장품 베이스로서 리포좀 에센스의 물성 평가 및 피부타입에 따른 만족도 평가)

  • An, Hyung Guen;Hyeon, Tong-Il;Yoon, Kyung-Sup
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.48 no.1
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    • pp.1-10
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    • 2022
  • Customized cosmetics are continuously mentioned as a trend in the cosmetics industry to respond to the recent rapid changes in the social environment and pursue individuality and diversity. Accordingly, four types of liposome essence corresponding to skin types were prepared by varying the ratio of liposome formulation and essence formulation as a customized cosmetic base that can be easily mixed and applied at the workplace. The volatilization residues of four types of liposome essence were measured and the nanoparticle size, polydispersity index, zeta potential and viscosity according to time for 90 d were measured, and Turbiscan was measured as a method for evaluating the stability of a colloidal dispersion system. In addition, a simple usability evaluation was performed for four types of liposome essence corresponding to the skin type. As a result, the amount of volatile residue in the four types of liposome essence was increased in dry products rather than oily ones, and the particle size showed a tendency to increase with time in the range of 165 to 175 nm, increasing up to 31.5%, and the polydispersity index was 0.23 to 0.26. There was little change with time, and the zeta potential was -74 to -72 mV, showing a slight decrease with time, but there was little change to the extent of a maximum decrease of 14.0%. Viscosity showed a decreasing trend with time in the range of 2,580 ~ 3,290 cps, showing a maximum decrease of 17.5%. In the turbiscan measurement, all of the turbiscan stability index, a measure of stability, were less than 1.0, indicating dispersion stability. In the overall simple usability satisfaction evaluation for skin types (6 points), products for oily skin (5.33 ± 0.75 points) > products for medium dry skin (5.13 ± 0.95 points) > products for dry skin (5.03 ± 0.96 points) > products for oily skin (4.80 ± 1.04 points) points) were evaluated in order. The four types of liposome essence corresponding to skin types with different ratios of liposome formulation and essence formulation were physically stable, and the possibility of application as a customized cosmetic base according to skin type was confirmed.

Analysis of Spatial Characteristics of Vacant House in Consideration of the Modifiable Areal Unit Problem (MAUP) - Focused on the Old Downtowns of Busan Metropolitan City - (공간단위 수정가능성 문제(MAUP)를 고려한 빈집 발생지역의 특성 분석 - 부산광역시 원도심 일대를 대상으로 -)

  • SEOL, Yu-Jeong;KIM, Ji-Yun;KIM, Ho-Yong
    • Journal of the Korean Association of Geographic Information Studies
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    • v.25 no.1
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    • pp.120-132
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    • 2022
  • Recently, the rapid increase in vacant houses in urban areas has caused various problems such as worsening urban landscape, causing safety accidents, crime accidents, and hygiene problems. According to the Statistics Korea Future Population Estimation results, the growth rate of Korean population and households is expected to continue to decrease, which is likely to lead to an increase in the occurrence of vacant houses. If the problem caused by the occurrence of vacant houses is neglected, it causes not only a physical decline such as a deterioration of the residential environment but also a social and economic decline. In order to solve this problem, it is necessary to grasp the spatial distribution characteristics of vacant houses at the local level considering the existence of regional characteristics and spatial influence. Therefore, in this study, in order to measure global spatial autocorrelation, the analysis was conducted centering on the old downtown area of Busan, where there are many vacant houses through Moran's I and Geographically Weighted Regression(GWR). In addition, the distribution of vacant houses in different spatial units in Eup_Myeon_Dong and Census was analyzed to evaluate the possibility of Modifiable Areal Unit Problem(MAUP), which differ in the results of spatial analysis as the spatial analysis units change. As a result of the analysis, the occurrence of vacant houses by Eup_Myeon_Dong in the old downtown area of Busan had spatial heterogeneity, and the spatial analysis results of vacant houses were different as the spatial analysis units were different. Accordingly, in order to understand the exact distribution characteristics of vacant house occurrence, spatial dimensions using the GWR model should be considered, and it is suggested that consideration of the MAUP is necessary.

Evaluation for applicability of river depth measurement method depending on vegetation effect using drone-based spatial-temporal hyperspectral image (드론기반 시공간 초분광영상을 활용한 식생유무에 따른 하천 수심산정 기법 적용성 검토)

  • Gwon, Yeonghwa;Kim, Dongsu;You, Hojun
    • Journal of Korea Water Resources Association
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    • v.56 no.4
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    • pp.235-243
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    • 2023
  • Due to the revision of the River Act and the enactment of the Act on the Investigation, Planning, and Management of Water Resources, a regular bed change survey has become mandatory and a system is being prepared such that local governments can manage water resources in a planned manner. Since the topography of a bed cannot be measured directly, it is indirectly measured via contact-type depth measurements such as level survey or using an echo sounder, which features a low spatial resolution and does not allow continuous surveying owing to constraints in data acquisition. Therefore, a depth measurement method using remote sensing-LiDAR or hyperspectral imaging-has recently been developed, which allows a wider area survey than the contact-type method as it acquires hyperspectral images from a lightweight hyperspectral sensor mounted on a frequently operating drone and by applying the optimal bandwidth ratio search algorithm to estimate the depth. In the existing hyperspectral remote sensing technique, specific physical quantities are analyzed after matching the hyperspectral image acquired by the drone's path to the image of a surface unit. Previous studies focus primarily on the application of this technology to measure the bathymetry of sandy rivers, whereas bed materials are rarely evaluated. In this study, the existing hyperspectral image-based water depth estimation technique is applied to rivers with vegetation, whereas spatio-temporal hyperspectral imaging and cross-sectional hyperspectral imaging are performed for two cases in the same area before and after vegetation is removed. The result shows that the water depth estimation in the absence of vegetation is more accurate, and in the presence of vegetation, the water depth is estimated by recognizing the height of vegetation as the bottom. In addition, highly accurate water depth estimation is achieved not only in conventional cross-sectional hyperspectral imaging, but also in spatio-temporal hyperspectral imaging. As such, the possibility of monitoring bed fluctuations (water depth fluctuation) using spatio-temporal hyperspectral imaging is confirmed.

Evaluation of Park Service in Neighborhood Parks based on the Analysis of Walking Accessibility - Focused on Bundang-gu, Seongnam-si - (보행접근성 분석에 기반한 근린공원의 공원서비스 평가 - 성남시 분당구를 대상으로 -)

  • Hwang, Hae-Kwon;Son, Yong-Hoon
    • Journal of the Korean Institute of Landscape Architecture
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    • v.52 no.1
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    • pp.59-70
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    • 2024
  • As urbanization progresses, the demand for parks and green space is increasing. Park green spaces in the city are important spaces in the city because they are recognized as spaces where people can freely engage in outdoor activities. The park service area is a measure that shows the extent to which services are provided based on distance. In this process, the concept of accessibility plays an important role, and walking, in particular, as the most basic means of transportation for people and has a great influence on the use of parks. However, the current park service area analysis focuses on discovering underprivileged areas, so detailed evaluation of beneficiary areas is insufficient. This study seeks to evaluate park service areas based on the pedestrian accessibility and the pedestrian network. Park services are services that occur when users directly visit the park, and accessibility is expected to be reflected in terms of usability. To quantify the pedestrian network, this study used space syntax to analyze pedestrian accessibility based on integration values. The integration values are an indicators that quantify the level of accessibility of the pedestrian network, and in this study, the higher the integration value, the higher the possibility of park use. The results of the study are as follows. First, Bundang-gu's park service area accounts for 43%, and includes most sections with high pedestrian accessibility, but some sections with good pedestrian accessibility are excluded. This can be seen as a phenomenon that occurs when residential areas and commercial and business areas are given priority during the urban planning process, and then park and green areas are selected. Second, based on Bundang-gu, the park service area and pedestrian accessibility within the park service area were classified by neighborhood unit. Differences appear for each individual neighborhood unit, and it is expected that the availability of the park will vary accordingly. In addition, even in areas created during the same urban planning process, there were differences in the evaluation of park service areas according to pedestrian accessibility. Using this, it is possible to evaluate individual neighborhood units that can be reflected in living area plans, and it can be used as a useful indicator in park and green space policies that reflect this in the future.

Distribution Characteristics of Land and River Aggregate Resources in Yeongam Area by Deposition Period (영암지역 육상 및 하천 골재의 퇴적 시기별 분포 특성)

  • Jin Cheul Kim;Sei Sun Hong;Jin-Young Lee;Ju Yong Kim
    • Economic and Environmental Geology
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    • v.57 no.2
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    • pp.243-251
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    • 2024
  • In this study, a surface geological survey was first conducted to investigate aggregate resources in the Yeongam area of Jeollanam-do, and a drilling survey was conducted in the lower part of the surface, which was difficult to identify through a surface geological survey, to determine the spatial distribution of aggregates. Drilling sites were selected considering the topographical development and Quaternary alluvium characteristics of the study area, and river aggregate drilling surveys were conducted at a total of 5 points and land aggregate drilling surveys were conducted at a total of 28 points. Borehole core sediments were classified into seven sedimentary units to determine whether they could be used as aggregates, and optically stimulated luminescence dating was performed on representative boreholes to measure the depositional period for each sedimentary unit. As a result of the study, most of the Yeongam area had a very wide river basin, so it was estimated that there would be a large amount of aggregate, but the amount of aggregate was evaluated to be very small compared to other cities and counties. Most of the unconsolidated sedimentary layers in the Yeongam area are composed of blue-grey marine clay with a vertical thickness of more than 10 m. The sand-gravel layer corresponding to the aggregate section is distributed in the lower part of the marine clay, thinly covering the bedrock weathering zone. This is because the amount of aggregates themselves is small and most of the aggregates are distributed at a depth of 10 m below the surface, which is currently difficult to develop, so the possibility of developing aggregates is evaluated to be very low. As a result of dating, it can be seen that the blue-grey marine clay layer is an intertidal sedimentary layer formed as the sea level rose rapidly about 10,000 years ago. The deposition process continued from 10,000 years ago to the present, and as a result, a very thick clay layer was deposited. This clay layer was formed very dominantly for about 6,000 to 8,000 years, and the sand-gravel layer in the section where aggregates deposited in the Pleistocene period can exist was measured to have been deposited at about 13.0 to 19.0 ka, and about 50 ka, showing that it was deposited as paleo-fluvial deposits before the marine transgression process.