• 제목/요약/키워드: Porous particle

검색결과 375건 처리시간 0.027초

얼음입자추출법을 이용한 알부민 함유 PLGA 담체의 제조 및 방출 거동 (Preparation and Release Behavior of Albumin-Loaded PLGA Scaffold by Ice Particle Leaching Method)

  • 홍금덕;서광수;김순희;김선경;강길선;신형식;김문석;이해방
    • 폴리머
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    • 제29권3호
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    • pp.282-287
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    • 2005
  • 조직공학적 장기재생에 있어서 필수적 요소인 생분해성 담체를 제조하기 위하여 새로운 방법인 얼음입자추출법을 사용하였다. 형광이 결합된 소 혈청 알부민(bovine serum albumin-fluoiescein isothiocyanate, FITC-BSA)과 락타이드-글리콜라이드 공중합체(PLGA)를 균일하게 혼합한 후에 제조된 얼음입자를 각각 다른 양을 첨가하여 다공성의 담체를 제조하였다. 모델 약물로 이용한 알부민의 방출 실험근 pH 7.4 인산염완충액을 사용하여 $37^{circ}C$, 100 rpm조건으로 항온조에서 28일 동안 수행하였다. 알부민의 방출은 형광 분광기를 통하여 FITC의 강도에 의해 결정되었으며 알부민의 방출 거동에 따른 담체의 형태학적 변화는 전자주사현미경을 이용하여 관찰하였다. 담체를 알부민이 용해된 용액에 단순히 함침시킨 방법에 비해 알부민을 함유하여 제조한 담체의 경우에 초기 방출량이 적고 일정한 방출거동을 보였다. 또한 알부민의 농도에 따른 실험에서 농도가 증가하여도 초기 방출량은 증가하지 않음을 확인할 수 있었다. 본 실험을 통해 PLGA를 이용하여 얼음입자 추출법으로 제조한 담체는 단백질 약물의 서방화가 훌륭하여 생체조직공학적 담체로서 응용 가능함을 확인하였다. 또한, 물 등께 의한 다공물질 추출 과정이 없기 때문에 사이토카인 등과 같은 수용성 인자들의 포접이 용이하여 조직공학적 바이오장기 재생에 유효할 것으로 사료된다.

가압다짐과 바텀애시 골재 크기 특성이 다공성 콘크리트의 열전도도에 미치는 영향 (Effects of the Compaction and Size of Bottom Ash Aggregate on Thermal Conductivity of Porous Concrete)

  • 양인환;정승태;박지훈
    • 한국건설순환자원학회논문집
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    • 제10권3호
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    • pp.195-203
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    • 2022
  • 본 논문에서는 바텀애시 골재의 크기 구성과 가압다짐이 다공성 콘크리트의 열전도도에 미치는 영향을 분석하였다. 본 실험연구에서는 바텀애시를 두 가지 입도의 골재를 섞은 SA와 한 가지 입도만을 갖는 DA를 사용하여 골재 특성을 파악한 후, 다공성 콘크리트 골재로 활용하였다. 물-바인더 비는 0.30으로 고정하고, 가압다짐을 0.5, 1.5 및 3.0 MPa을 콘크리트 시편에 적용하였다. 단위중량, 총 공극률 및 열전도도를 측정하고 분석을 수행하였다. 가압다짐이 증가할 때 단위중량과 열전도도는 증가하고 총공극률은 감소하였다. DA 사용 콘크리트에 비해 SA 사용 콘크리트의 단위중량과 열전도도는 크고 총공극률은 작게 나타난다. 또한, 오븐건조상태 시편의 열전도도가 기건상태 시편의 열전도도보다 낮은 결과를 나타냈다. 회귀분석을 통해 다공성 콘크리트의 단위중량, 총 공극률 및 열전도도와의 상관관계를 제시하였다. 열전도도와 단위중량은 서로 비례하는 상관관계를 나타내며, 열전도도와 총공극률은 서로 반비례하는 상관관계를 나타냈다.

분진 유입 방식에 따른 세라믹 캔들 필터 집진장치의 집진 및 탈진 특성 비교 연구 (Comparison Research of Filtration and Regeneration Characteristics of Ceramic Candle Filter System at Different Inflow Pattern of Dusty Gas)

  • 박석주;임경수;임정환
    • 한국신재생에너지학회:학술대회논문집
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    • 한국신재생에너지학회 2008년도 춘계학술대회 논문집
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    • pp.341-344
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    • 2008
  • Computational studies have been performed to analyze the particle loadings onto the filters according to the different inflow pattern of dusty gas and the flow uniformities on the filter surface of back-blown gas at different permeability of porous media setup at the filter outlet. This is preliminary study to find how we can reduce the regeneration time and improve the regeneration efficiency of filters with dust layer.

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양극 산화된 $TiO_2$ nanotube를 이용한 수소 생산 연구 (Hydrogen production by anodized $TiO_2$ nanotube under UV light irradiation)

  • 홍원성;박종혁;한귀영
    • 한국신재생에너지학회:학술대회논문집
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    • 한국신재생에너지학회 2008년도 춘계학술대회 논문집
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    • pp.495-498
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    • 2008
  • Photocatalytic water splitting into $H_2$ and $O_2$ using semiconductors has received much attention, especially for its potential application to direct production of $H_2$ for clean energy from water utilizing solar light energy. Since the report of Fujishima and Honda on the water splitting by photoelectrochemical cells, numerous different semiconducting materials have been used as photocatalysts for hydrogen generation from water. Among them, platinized titania significantly accelerates hydrogen production from water. For geometrical improvement of $TiO_2$ particle, porous $TiO_2$ structure was proposed and studied such as nanofiber, nanorod and nototubes. This research focuses on finding out the optimum temperature and electrolyte to produce $H_2$ by solar water splitting.

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Development of Drainage Asphalt Mixture Using Large Size Aggregate and Its Performance on Test Pavement

  • Ogino Shoji;Ohmae Tatsuhiko;Matsumoto Yuki;Yamada Masaru
    • 한국도로학회논문집
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    • 제8권1호
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    • pp.107-117
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    • 2006
  • Recently, there has been a remarkable trend of using aggregates at sizes smaller than 13 mm for drainage asphalt pavement (DAP) in order to reduce the noise generated between vehicle tires and road surface. These DAPs have their performance and durability seriously worsen after several years in-service due to the clogging of void space and the abrasion. This paper proposes the use of large size aggregates in porous asphalt mixtures to overcome these defects. Results of laboratory and field experiments on asphalt mixtures with several aggregate gradations are investigated and compared. The study focuses on advantages of DAP using large size aggregate and on particle size combinations containing no fine aggregates of size 2.36 mm or less, which have not been considered in current engineering practice.

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ZnO가 담지된 실리카 겔 연구 (A Study on the ZnO Supported Silica Gel)

  • 김시영;김민연;주창식
    • 동력기계공학회지
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    • 제15권4호
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    • pp.75-78
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    • 2011
  • There are various types of materials used in electronic industry, such as electrode material, conductor, insulator, anode, cathode and semiconductor. Electrode material type is Cu, Ti, ZnO and so on. Especially if we use mixed ZnO in soil cement or silica gel, we can have advantages in ice road to prevent freezing. We have great impact if we use supported in inorganic substances like silica gel. In this paper we have studied that ZnO supported silica gel and its properties. Zinc acetate dissolved in distilled water were loaded on the silica gel by the reaction with ammonia at $80^{\circ}C$. And we investigated particle structures of ZnO by scanning electron microscopy(SEM) and X-ray diffraction(XRD).

층상 실리케이트 주형을 이용한 층상 카본의 합성 (Preparation of Layered Carbon Using Layered Silicate Template)

  • 정은일;정순용;권오윤
    • 공업화학
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    • 제16권1호
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    • pp.68-73
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    • 2005
  • 층상 실리케이트를 주형으로 이용하여 실리케이트의 층간에 pyrolized fuel oil (PFO)를 삽입하고 열분해시킨 후 실리케이트 골격을 용출 제거함으로써 다공성 층상카본을 제조하였다. 층상카본의 입자모양은 층상실리케이트 주형과 유사한 판상 형태이며, d-spacing은 0.78~0.82 nm로 일정한 값을 나타내었다. 실리케이트와 PFO의 혼합비율과 열처리 온도, 열처리 시간에 따른 비표면적은 $30{\sim}576m^2/g$로 크게 다른 값을 나타내었다.

Effects of Surface Geometry on Polyelectrolyte Adsorption

  • Park, Young-G.;Kim, Key-Seek;Sung, Ki-Chun
    • 한국응용과학기술학회지
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    • 제17권2호
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    • pp.149-156
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    • 2000
  • For the adsorption of polyelectrolyte at the surface of polyacrylamide gel particle, preferential adsorption of the large polyelectrolyte such as DNA is governed by the surface area of an adsorbent. The adsorption equilibrium constant can be varied by surface geometry of porous polymer, and it can be described as a function of ionic strength and surface area. Physical parameters affecting the adsorption were estimated using the theoretical governing equation of polyelectrolyte which electrophoretically moved along the column, and geometrical surface area was estimated by Waldman-Mayer's physical model. The separation of polyelectrolytes was studied using the physical parameters estimated by ionic strength and surface geometry.

나노 구리 분말의 냉간정수압 공정에 대한 치밀화 거동 해석 (Analysis of Densification Behavior of Nano Cu Powders during Cold Isostatic Pressing)

  • 윤승채;김형섭;이창규
    • 한국분말재료학회지
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    • 제11권4호
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    • pp.341-347
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    • 2004
  • In the study, a hybrid constitutive model for densification of metallic powders was applied to cold isostatic pressing. The model is based on a pressure-dependent plasticity model for porous materials combined with a dislocation density-based viscoplastic constitutive model considering microstructural features such as grain size and inter-particle spacing. Comparison of experiment and calculated results of microscale and nanoscale Cu powders was made. This theoretical approach is useful for powder densification analysis of various powder sizes, deformation routes and powder processing methods.

CHARACTERISTICS OF RESIDUAL CARBON DERIVED FROM THE COMBUSTION OF VACUUM RESIDUE IN A TEST FURNACE

  • Park, Ho-Young;Seo, Sang-Il
    • Environmental Engineering Research
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    • 제12권3호
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    • pp.109-117
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    • 2007
  • The characteristics of carbonaceous particles collected from the combustion of Vacuum Residue (VR) in a test furnace have been investigated. The physical and chemical characterization includes particle size, scanning electron microscopy of the surface structure, measurement of porosity, surface area and density, EDX/XRD analyses and measurement of chemical composition. The studies show that the carbonaceous VR particles are very porous and spheroidal, and have many blow-holes on the surface. The particles become smaller and more sponge-like as the reaction proceeds. The present porosity of VR particles is similar to that of cenospheres from the combustion of heavy oil, and the majority of pores are distributed in macro-pores above $0.03\;{\mu}m$ in diameter. Measurements of pore distribution and surface area showed that the macro-pores contributed most to total pore volume, whereas the micro-pores contributed to total surface area.