• Journal of Distribution Science
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• v.13 no.12
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• pp.65-71
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• 2015

Purpose - Domestic cooperatives tend to increase during the establishment of cooperatives and gradually through the basic law of social needs. However, only cooperatives' qualitative grow this secured without blessings, and their quantitative growth through government support is questionable. The purpose of this study is to analyze the agricultural cooperatives established through the Distribution System Cooperatives Basic Law, which was enacted in January 2012. Subsequently, establishing agricultural cooperatives was done briskly. However, cooperatives established rapidly after the founding of the Basic Law encountered problems. Research design, data, and methodology - To assess the performance of selected agricultural cooperatives, data were analyzed using the methodological Analytic Hierarchy Process (AHP) approach. The AHP is a set of systematic procedures to hierarchically analyze the elements of any problem. Using a survey on expertise, a series of comparative determinations of each pair is performed to evaluate the relative strengths and the strengths of the impact between elements within the hierarchy. A survey was conducted on 10 small agricultural cooperatives using AHP analysis for the examination. The purpose of such research and analysis is to recommend a direction for future policies aimed at small agricultural cooperatives. Result - This study applied three types of policy evaluation criterion, including market expansions, organizations, and cooperative projects, and 12 types of small agricultural cooperative policy measures. Market expansion policies for agricultural cooperatives are classified into four categories: school meals, direct transactions, shopping malls, and wholesale markets. Organizational policies for agricultural cooperatives are classified into four types: existing sales channel management, education, preventing free riding, and enlarging members. Cooperative project policies in agricultural cooperatives are classified into four policy areas: cooperation between cooperatives, community contribution, joint businesses, and government links. In this paper, the growth priority in agricultural cooperative policies is analyzed by applying policy evaluation criteria on the basis of a survey on expertise. The priorities of the policy program are also analyzed using a decision analytic hierarchy process. The results indicate that market expansion is the most important policy evaluation criterion therefore, improving direct transactions, school meals, management of existing sales channels, and shopping malls are crucial policy measures. In contrast, the cooperation of cooperatives, expansion of union members, and cooperation with the government were found to have low priority. Conclusions - Agricultural cooperatives should develop plans as follows. Small agricultural cooperatives need to secure school meals and direct transactions for market expansion, restructure marketing strategies to manage existing sales channels, and, finally, increase education and training for sustainable organizational development. This study has the following limitations. Because the subject of the investigation is a new cooperative, determining its sustainable growth is difficult. Therefore, through analysis and a continuous study of cooperatives, future research is expected to show that modifying the direction of agriculture cooperatives is necessary.

• Journal of Hydrogen and New Energy
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• v.20 no.1
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• pp.9-21
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• 2009

As one of the alternative solution for energy and environmental issues such as climate change, energy security, oil price, etc., hydrogen energy has been getting so much attentions these days. This paper analyzed the $CO_2$ emission, costs, and energy consumptions when the hydrogen energy was introduced to transportation, specifically in Sedan sector using the energy system model, MARKAL. As results, 21.5% of $CO_2$ emission in 2040 could be reduced and additional 76 billion dollars will be needed in the high energy price scenario. The amount of energy saving mainly due to the replacement of existing car to hydrogen vehicle was 16% of the final energy consumption in 2040.

• Proceedings of the Korea Technology Innovation Society Conference
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• 2005.05a
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• pp.306-320
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• 2005

Government-sponsored Research Institutes(GRIs) have made a great contribution to the development of Korea's Science and Technology(S&T). However, recently GRIs are facing the challenge of many problems. For instance, absence of reasonable strategies, insufficient resources and so on. Therefore, many GRIs are being asked for solving their problems with successful strategic management. This paper suggests a strategic management model to solve their problems and to cope with the changing S&T environment. In this paper, The strategic management model for GRIs which was thoroughly considered strategic management process suggested to response the need of their change and to perform their strategic management successfully. As a case of GRIs to apply this model, in this paper, Korea Basic Science Institute(KBSI) that is part of the Korea Research Council of Fundamental Science and Technology(KRCF) was analyzed. As a result of analysis with this model which applied to KBSI, various strategies and alternatives were suggested.

• International Journal of Stem Cells
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• v.17 no.3
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• pp.319-329
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• 2024

Leucine-rich repeat kinase 2 (LRRK2), a large GTP-regulated serine/threonine kinase, is well-known for its mutations causing late-onset Parkinson's disease. However, the role of LRRK2 in glioblastoma (GBM) carcinogenesis has not yet been fully elucidated. Here, we discovered that LRRK2 was overexpressed in 40% of GBM patients, according to tissue microarray analysis, and high LRRK2 expression correlated with poor prognosis in GBM patients. LRRK2 and stemness factors were highly expressed in various patient-derived GBM stem cells, which are responsible for GBM initiation. Canonical serum-induced differentiation decreased the expression of both LRRK2 and stemness factors. Given that LRRK2 is a key regulator of glioma stem cell (GSC) stemness, we developed DNK72, a novel LRRK2 kinase inhibitor that penetrates the blood-brain barrier. DNK72 binds to the phosphorylation sites of active LRRK2 and dramatically reduced cell proliferation and stemness factors expression in in vitro studies. Orthotopic patient-derived xenograft mouse models demonstrated that LRRK2 inhibition with DNK72 effectively reduced tumor growth and increased survival time. We propose that LRRK2 plays a significant role in regulating the stemness of GSCs and that suppression of LRRK2 kinase activity leads to reduced GBM malignancy and proliferation. In the near future, targeting LRRK2 in patients with high LRRK2-expressing GBM could offer a superior therapeutic strategy and potentially replace current clinical treatment methods.

• Ocean and Polar Research
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• v.44 no.4
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• pp.339-353
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• 2022

The purpose of this research is to conduct an empirical analysis regarding Korea's 'Marine Protected Areas (MPA)' from an international comparative perspective. The authors would like to present the policy direction of marine protected areas based on the result of the research. The result of this study can be summarized in the following manner: First, the total designated size of marine protected areas in Korea is very small compared to the sizes of other OECD nations . Second, while some nations have expanded the extent of marine protected areas in accordance with international agreements and criteria, Korea has not done so. Accordingly, we propose the designated dimensions of marine protected areas should be constantly expanded to keep pace with international trends.

• Laboraroty Animal Research
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• v.34 no.4
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• pp.160-165
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• 2018

Breast cancer remains the second leading cause of cancer death among woman, worldwide, despite advances in identifying novel targeted therapies and the development of treating strategies. Classification of clinical subtypes (ER+, PR+, HER2+, and TNBC (Triple-negative)) increases the complexity of breast cancers, which thus necessitates further investigation. Mouse models used in breast cancer research provide an essential approach to examine the mechanisms and genetic pathway in cancer progression and metastasis and to develop and evaluate clinical therapeutics. In this review, we summarize tumor transplantation models and genetically engineered mouse models (GEMMs) of breast cancer and their applications in the field of human breast cancer research and anti-cancer drug development. These models may help to improve the knowledge of underlying mechanisms and genetic pathways, as well as creating approaches for modeling clinical tumor subtypes, and developing innovative cancer therapy.

• Journal of Radiation Protection and Research
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• v.42 no.1
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• pp.56-62
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• 2017

Background: To help future generations make accurate value judgments about nuclear power generation and radiation, this study will provide an effective education plan suitable for South Korea by applying and analyzing programs for the understanding of nuclear power within the diversely operated programs in the current Korean education system. Materials and Methods: This study analyzed the difference in educational effects by operating a 13-session regular curriculum for one semester and a one-session short-term curriculum from March to July 2016. Results and Discussion: As a result of operating a 13-session model school and a one-time educational program to analyze behavior changes against the traditional learning model, it was found that all elementary, middle and high school students showed higher acceptability of nuclear power in South Korea. The variation was greater for the model school than the short-term program. Conclusion: To prevent future generations from making biased policy decisions stemming from fear regarding nuclear power, it is necessary to bolster their value judgments in policy decisions by acquiring sufficient information about nuclear power generation and radiation through educational programs.

• Health Policy and Management
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• v.24 no.4
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• pp.396-412
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• 2014

Background: As a reform plan of health care system, Accountable Care Organization (ACO) has became an object of attention in the United States after Patient Protection and Affordable Care Act was enacted. ACO is a group of various health care providers and provide coordinated care to its assigned beneficiaries. If ACOs improve the quality level and reduce the cost of care, they can get financial incentives. Under the discussion for a quite long time and demonstration projects, ACO has been established. We aimed to analysis and discuss the history, policy mechanism, contents, status and outcomes of ACO. Also, we intended to suggest political implication Korean health care system with regard to ACO. Methods: We searched the articles related ACO in PubMed and selected several available papers about ACO. Total 56 studies were reviewed and categorized three parts; demonstration projects for formation of ACO, policy mechanism and agenda, empirical results of ACO performance. Results: As a result, establishment of ACO was successful partly in the US. It seems to be due to various project and pilot test for verification in the long time. The empirical effect of ACO was also identified in a few study but it needs more evidences to judge its positive effect. Conclusion: In Korea, there are arguments for the application of ACO. However it is difficult to implement a ACO by different political conditions between Korean and US. Nevertheless ACO proposed us the necessity of paradigm shift in our health policy and could be significant to national policy orientation in the future.

• The Journal of Industrial Distribution & Business
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• v.11 no.3
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• pp.29-38
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• 2020

Purpose: Geographical relocation has been conducted to alleviate overcrowding and to support balanced regional development in many countries. Previous studies have seldom examined the effectiveness of relocation on job and life dissatisfaction, particularly in the public sector. The purpose of this study is to investigate the determinants of relocation on job and life dissatisfaction. Proposed research questions include the following: i) do working conditions in the new workplace and interactivity affect job dissatisfaction? ii) do social infrastructure and social activity in the new location affect life dissatisfaction? and iii) is there a relationship between job and life dissatisfaction? Research Design, data, and methodology: The study collected data via an online survey and applied statistical analyses such as factor analysis, regression, and ANOVA. Results: The results of this study found that proposed determinants excluding mobility inefficiency and decision-making affect job and life dissatisfaction. The results also showed that there are relationships between job and life dissatisfaction. Conclusions: The results of this study provide both managerial and policy implications of relocation for the public sector. The results of this study implied that better policy should be designed to increase job and life satisfaction that also accounts for the realities of relocation.

• Journal of the Korean Home Economics Association
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• v.50 no.6
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• pp.119-130
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• 2012

This study attempted to investigate school participation experiences and the need for a school-participation leave for employed parents. A school participation leave is a paid or unpaid leave that guarantees workers to take time-off for school participation regarding children's educational purposes. We reviewed cases of school participation in other countries. There are similar types of educational leave in Russia, Greece, Italia, Sweden, Swaziland, and South Africa. We collected survey data from 1,194 employed parents (794 fathers and 400 mothers) whose children attend kindergarten, elementary, middle, or high-school. This study compares school participation experiences and needs by parent gender. The results showed that 62 % of the fathers and 80 % of the mothers participated in any type of school meetings and events at least once in the previous year. Fathers attended school events such as art festivals and mothers attended PTA meetings, school events, and parent-teacher conferences. The most frequently mentioned reason for non-participation among parents was related to work. A total of 87.7% of the parents agreed that a school-participation leave should be introduced. The results of the logistic regression showed that mothers compared to fathers, college graduates compared to post-secondary graduates, those whose children attended preschool or elementary school compared to high school, and those who had longer working hours were more likely to agree on the introduction of school participation leave. In conclusion, a policy intervention such as school-participation leave should be considered to provide employed parents time to be involved in their children's education and participate in school activities.