• 제목/요약/키워드: Polarization effect

검색결과 894건 처리시간 0.03초

Polarization of THP-1-Derived Macrophage by Magnesium and MAGT1 Inhibition in Wound Healing

  • Mun Ho Oh;JaeHyuk Jang;Jong Hun Lee
    • Archives of Plastic Surgery
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    • 제50권4호
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    • pp.432-442
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    • 2023
  • Background Macrophages play a major role in wound healing and prevent infection from the outside. Polarization conversion of macrophages regulates aspects of inflammation, and two macrophages, M1 (classically activated) and M2 (alternatively activated), exist at both ends of broad-spectrum macrophage polarization. Thus, we aimed to investigate whether macrophage polarization can be artificially regulated. To this end, MgSO4 and small-interfering RNA (siRNA) targeting magnesium transport 1 (MAGT1) were used to investigate the effects of intracellular magnesium (Mg2+) concentrations on the differentiation of macrophages in vitro. Methods THP-1 derived macrophages maintained in a culture medium containing 5 mM MgSO4 and siRNA to inhibit the expression of MAGT1. As comparative groups, THP-1 derived macrophages polarized into M1 and M2 macrophages by treatment with M1, M2 inducer cytokine. The polarization status of each group of cells was confirmed by cell surface antigen expression and cytokine secretion. Results We found that MgSO4 treatment increased CD163 and CD206, similar to the effect noted in the M2 group. The expression of CD80 and HLA-DR was increased in the group treated with MAGT1 siRNA, similar to the effect noted in the M1 group. Functional assays demonstrated that the group treated with MgSO4 secreted higher levels of IL-10, whereas the MAGT1 siRNA-treated group secreted higher levels of IL-6 cytokines. Additionally, the conditional medium of the Mg2+ treated group showed enhanced migration of keratinocytes and fibroblasts. Conclusion Mg2+ can help to end the delay in wound healing caused by persistent inflammation in the early stages.

광 파이버의 패러데이 효과를 이용한 전류측정용 프로브 설계 (Design of Current Probe Using Faraday Effect of Optical Fiber)

  • 강항식;김철주
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 1995년도 하계학술대회 논문집 C
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    • pp.1278-1280
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    • 1995
  • A probe type fiber-optic sensing techique for electric current measurement is applied in this paper. The technique is based on the Faraday effect which meaning is that polarization state of light is rotated by magnetic field. In experiment, test wire is located at inside and outside of the probe to be measured. The experimental results prove not only linear property, but also polarization rotation property according to the distance from outside of probe.

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PMD Effect on the Clock-based Optimum Dispersion Compensation Monitoring Technique

  • Kim, Sung-Man
    • Journal of the Optical Society of Korea
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    • 제13권1호
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    • pp.112-115
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    • 2009
  • We investigate the effect of polarization-mode dispersion (PMD) on the optimum dispersion compensation (ODC) monitoring and nonlinear penalty in optical transmission systems. We report that PMD may reduce the fiber nonlinearity. We also report that the monitoring error of the clock-based ODC monitoring technique decreases after the first-order PMD compensation. A simple explanation of this phenomenon is shown.

Comparison with Polarization Characteristic of Polymers

  • Choi, Chil-Nam;Yabg, Hyo-Kyung
    • 한국환경과학회:학술대회논문집
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    • 한국환경과학회 2001년도 가을 학술발표회 발표논문집
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    • pp.188-190
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    • 2001
  • We carried out to measure the variations of potential with current density polymers. The results were particularly examined to identify the influences on corrosion potential and corrosion rate of various factors including temperature and pH. The Tafel slope for anodic dissolution was determined by the polarization effect depending on these conditions. The optimum conditions were established for each case. The second anodic current density peak and maximum passive current density were designated as the relative corrosion sensitivity($I_{r}I_{f}$). The mass transfer coefficient value (${\alpha}$) was determined with the Tafel slope for anodic dissolution based on the polarization effect with optimum conditions.

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Effect of iron on the proteolytic activity of live Uronema marinum (Ciliata: Scoticociliatida) measured by fluorescence polarization

  • 이은혜;권세련;최승혁;김기홍
    • 한국어병학회지
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    • 제19권1호
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    • pp.83-86
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    • 2006
  • Effect of iron on the extracellular proteolytic activity of live Uronema marium was determined by fluorescence polarization (FP) method. Supplementation of 0.5 and 5.0 μM iron significantly increased caseinolytic activity of live U. marinum. In contrast, supplementation of 50 μM iron showed no significant differences in FP values compared to the control. The present result suggests that iron in cultured water or skin tissue of olive flounder may influence on the penetration and establishment of U. marinum, correlating with modulation of extracellular protease activity of the ciliates.

농도분극현상을 이용한 담수화 과정에서의 나노채널 개수 및 운전조건 영향에 대한 실험 적 연구 (Experimental study on effect of nanochannel numbers and working conditions for concentration polarization based desalination process)

  • 이용남;김대중
    • 한국가시화정보학회지
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    • 제13권2호
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    • pp.16-21
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    • 2015
  • Concentration polarization(CP) phenomena show great potential on desalination technology. As we can control the dimension of silicon based nanochannel system, it can be used to model ion exchange membrane. In this study, to investigate the effect of nanochannel number and working conditions on the CP based desalination process, nanochannel based microfluidic system is fabricated. First, we optimized nanochannel number and working conditions to conduct visualization study on CP based desalination process. Second, we visualized the desalination process with fluorescent dye in the desalination chip. We also visualized that the particles also can be removed by the CP based desalination process.

아연-니켈합금 전기도금층의 부식특성 (Corrsion of Ni-Ze Electrodeposited Alloy)

  • 예길촌;신현준
    • 한국표면공학회지
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    • 제21권2호
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    • pp.39-46
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    • 1988
  • Corrosion behavior of 5-26wt% Ni-Zn electrodeposited alloys was investigated by means of dipping electrochmical polarization measurement and galvanic coupling test. The weight loss and anodic polarization curve of coatings were measured by means of dipping and polarization measurement respectively. The galvanic protection effect of alloy coatings was measured by galvanic coupling test and the surface morpholgy of coatings was observed after corrosion testing. Our findings support thous of previous investigations showing that ${\gamma}$single phase coatings, while galvanic pprotection effect of dual phase coatings improved in comparison with ${\gamma}$single phase coating. The formation of colony in coating of ${\gamma}$and η+${\gamma}$ dual phsae caused the localized corrsion and increased the corrosion rate of the Ni-Zn coating.

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인발률에 따른 자동차 냉각 배관용 Al 합금의 부식 특성에 관한 연구 (Effect of Drawing Rate on the Corrosion Behavior of Al Alloy Tubes for Automotive Cooling System)

  • 박병준;김정구;안승호;곽동호;손현수
    • 대한금속재료학회지
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    • 제46권8호
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    • pp.489-494
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    • 2008
  • The effect of drawing rate on the electrochemical properties of 3003 Al alloys in 5 wt.% NaCl solution was investigated by electrochemical techniques (potentiodynamic polarization test, potentiostatic polarization test, electrochemical impedance spectroscopy (EIS)) and surface analyses (OM, SEM, EDS). Four kinds of automotive pipe materials were prepared (raw material, drawing rate = 5, 10, 15%). As the drawing rate of Al alloy tube increased, the pitting corrosion resistance increased due to the enrichment of Al oxides on the surface.

Effect of Out-of-plane Retardation of Substrate Film on the Viewing-angle Dependence of Transmittance in a Display Device

  • Ahn, Sumin;Lee, Ji-Hoon
    • Current Optics and Photonics
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    • 제5권1호
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    • pp.45-51
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    • 2021
  • The effect of the out-of-plane retardation (Rth) of a substrate film on the viewing-angle dependence of transmittance (TR) in a display device was investigated. When the polarization state of input light deviates from the transmission axis of the polarizer, Rth of the substrate film induces inhomogeneous viewing-angle dependence of TR. The inhomogeneity of TR gets worse for greater values of of Rth. The inhomogeneous TR profile can be eliminated by inserting compensation films, which convert the input polarization state to the linear polarization state parallel to the transmission axis of the polarizer.

칼코게나이드 박막에서 편광 빔 회절 효율의 전계 효과 의존성 (The dependence of the electric field effect of diffraction efficiency using polarization beam on calcogenide thin films)

  • 장선주;여철호;박정일;이현용;정홍배
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 1999년도 하계학술대회 논문집 D
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    • pp.1861-1863
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    • 1999
  • The polarization gratings were fabricated in chalcogenide $As_{40}Ge_{10}Se_{15}S_{35}$ thin film applicable to a medium of the polarization holography and their diffraction efficiencies$(\eta)$ were monitored by real-time measurement. The polarization gratings prepared consisted of the multi-layer thin film system. As a method to improve the $\eta$, we have investigated its change for the field effect. As the results, the value of $\eta$ strongly depended on the voltage applied to the film and the maximum value, $\eta_{max}$ was enhanced to be about 4 times in comparison with that of not biased sample. In addition, an increase in the $\eta$ can be estimated to be due to additional creation of new defects caused by the electric field across the film.

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