• Title/Summary/Keyword: Poisons

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Paralytic shellfish poisons in the cultured mussel Mytilus edulis galloprovincialis (양식(養植) 진주담치의 마비성패독(痲痺性貝毒))

  • Jeon, Joong-Kyun;Huh, Hyung-Tack
    • 한국해양학회지
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    • v.24 no.2
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    • pp.79-83
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    • 1989
  • Attempts were made to analyze the toxin composition of the toxic mussel Mytilus edulis galloprovincialis which were collected from aquaculture pond in Apr. 1988 in Hachung, Koje, southern Korea. The toxins were partially purified from the ethanolic extract of the mussel digestive glands by activated charcoal and Bio Gel P-2 column chromatography. HPLC analysis demonstrated that the toxin consisted mainly of gonyautoxin 1-4 (GTX 1-4), along with trace amounts of saxitoxin (STX) and protogonyautoxin 1-2 (PX 1-2).

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High Cadmium Levels in Cured Meat Products Marketed in Nigeria - Implications for Public Health

  • Adejumo, Olufunmilayo E;Fasinu, Pius S;Odion, Judith E;Silva, Boladale O;Fajemirokun, Timothy O
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.4
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    • pp.1933-1936
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    • 2016
  • Heavy metals are known to disrupt important physiological processes in living cells, and have been responsible for various pathological conditions with possible contributions to cancer development. Food contamination have been identified as one of the ways humans are exposed to heavy metals. In developing countries like Nigeria, the regulatory framework for enforcing compliance with globally acceptable exposure to deleterious contaminants is poor. In the current study, thirteen samples of cured meat products of diverse origin marketed in South-west Nigeria were evaluated for lead, cadmium, chromium and nickel contents using the atomic absorption spectroscopy technique. All the samples analysed contained cadmium between 0.35 and 1.20 ppm, levels considered higher than acceptable limits in consumable products. Lead, chromium and nickel were not detected in any of the samples. As known cumulative poisons, there is the need for stringent regulatory control of these heavy metals in cured meat products imported into or produced indigenously in the country in order to minimize the risks to public health.

ANALOG COMPUTING FOR A NEW NUCLEAR REACTOR DYNAMIC MODEL BASED ON A TIME-DEPENDENT SECOND ORDER FORM OF THE NEUTRON TRANSPORT EQUATION

  • Pirouzmand, Ahmad;Hadad, Kamal;Suh, Kune Y.
    • Nuclear Engineering and Technology
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    • v.43 no.3
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    • pp.243-256
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    • 2011
  • This paper considers the concept of analog computing based on a cellular neural network (CNN) paradigm to simulate nuclear reactor dynamics using a time-dependent second order form of the neutron transport equation. Instead of solving nuclear reactor dynamic equations numerically, which is time-consuming and suffers from such weaknesses as vulnerability to transient phenomena, accumulation of round-off errors and floating-point overflows, use is made of a new method based on a cellular neural network. The state-of-the-art shows the CNN as being an alternative solution to the conventional numerical computation method. Indeed CNN is an analog computing paradigm that performs ultra-fast calculations and provides accurate results. In this study use is made of the CNN model to simulate the space-time response of scalar flux distribution in steady state and transient conditions. The CNN model also is used to simulate step perturbation in the core. The accuracy and capability of the CNN model are examined in 2D Cartesian geometry for two fixed source problems, a mini-BWR assembly, and a TWIGL Seed/Blanket problem. We also use the CNN model concurrently for a typical small PWR assembly to simulate the effect of temperature feedback, poisons, and control rods on the scalar flux distribution.

Development of a DDA+PGA-combined non-destructive active interrogation system in "Active-N"

  • Kazuyoshi Furutaka;Akira Ohzu;Yosuke Toh
    • Nuclear Engineering and Technology
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    • v.55 no.11
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    • pp.4002-4018
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    • 2023
  • An integrated neutron interrogation system has been developed for non-destructive assay of highly-radioactive special nuclear materials, to accumulate knowledge of the method through developing and using it. The system combines a differential die-away (DDA) measurement system for the quantification of nuclear materials and a prompt gamma-ray analysis (PGA) system for the detection of neutron poisons which disturb the DDA measurements; a common D-T neutron generator is used. A special care has been taken for the selection of materials to reduce the background gamma rays produced by the interrogation neutrons. A series of measurements were performed to test the basic performance of the system. The results show that the DDA system can quantify plutonium of as small as 20 mg and it is not affected by intense neutron background up to 1.57 × 107 s-1 and gamma ray of 4.43 × 1010 s-1. The gamma-ray background counting rate at the PGA detector was reduced down to 3.9 × 103 s-1 even with the use of the D-T neutron generator. The test measurements show that the PGA system is capable of detecting 0.783 g of boron and about 86.8 g of gadolinium in 30 min.

The Dietary Behavior, Dietary Intakes and Internet Searches Reagarding by Disease in College Students Participating in a Nutrition Education Web Class (인터넷 영양교육 참여 대학생의 질병유무에 따른 식행동, 식이섭취 및 인터넷 사용에 관한 연구)

  • 유혜은;성현이;곽진오;장경자
    • Korean Journal of Community Nutrition
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    • v.7 no.5
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    • pp.696-704
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    • 2002
  • The purpose of this study was to investigate the dietary behavior, dietary intakes and internet searches regarding diseas by college students participating in a nutrition education web class. The study subject were 1184 college students and crosssectional survey was conducted by a self-administered questionnaire. The questionnaire deal with anthropometric data, diseas, dietary behaviors, dietary intakes, and the use of nutrition information via the internet. The data was analyzed using a SPSS PC program. Disease group was 19.6% (male: 17.1%, female: 21.9%) and non-disease group was 80.4% (male: 82.9%, female: 78.1%) of subjects. As for the kinds of diseas, the male disease group had stomach diseas (15.7%), ozena (15.7%), hepatitis (10.8%) and allergic disease (7.8%), etc, and the female disease group had stomach diseas (32.8%), allergic diseas (12.0%), bronchitis and bronchial asthma (10.4%), anemia (7.2%), and constipation (1.6%), etc. Non-disease group showed significantly higher irregularity of meal time compared to disease group. Also, Disease group showed significantly higher concern about nutrition and health, worse recognition of theirown nutrition and health satus, and made greater efforts to prevention diseas compared to the non-diseas group. In the male subjects, the average intake of Calories, Vitamin $B_2$ and calcium was lower than the Korean RDA and in the female subjects, those of Calories, calcium and Fe were lower than the Korean RDA. Most of the diseas (97%) and the non-disease (98.2%) groups had positive attituds toward the usefulness of internet nutrition information. The disease group showed a higher confidence in the internet nutrition information and recognition of internet information on poisons compared to the non-diseas group. However, this difference was not significant. Therefore. it is necessary to provide sientifically proven nutrition of information via the internet for college students in order to promote healthful lifestyles and to prevent diseas.

Development and Use of Data for Chemical Risk Assessment (화학물질 유해성 평가를 위한 정보의 작성 및 활용)

  • Rim, Kyung-Taek;Kim, Hyun-Ok;Kim, Young-Kyo;Cho, Hae-Won;Ma, Yong-Seok;Lee, Kwon-Seob;Lim, Cheol-Hong;Kim, Hyeon-Yeong;Yang, Jeong-Seon
    • Environmental Analysis Health and Toxicology
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    • v.22 no.1 s.56
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    • pp.91-101
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    • 2007
  • The new chemicals are developed and circulated without the verified toxicity data. So, the accidents and occupational diseases, such as explosion, fire, suffocation about deadly poisons etc. are frequently to workers. Classifications of chemicals suited with guideline and an offer of correct chemical information data are the molt important thing for the establishment of suitable chemical management system. The GHS (Globally Harmonized System of classification and labeling of chemicals) is based with the chemical classifications and unification plan. The warning symbol and phrases are established for improvements of chemical information data system. According to these unified and improved systematic form of data, and the chemical information data, the workplaces will be presented many chemical safety and risk data correctly. In this paper, we will present constructions and accomplishment contents-based chemical management of workplace through development of chemical information data and the nice using for new chemical investigation and risk assessment of chemicals in workplaces.

The Problem and Challenges of Pest Control in Korea (우리나라의 쥐 및 위생해충 방제에 대한 문제점과 개선방향)

  • 전순표
    • Journal of environmental and Sanitary engineering
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    • v.7 no.2
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    • pp.129-140
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    • 1992
  • Rats and Cockroaches are the most problematic pests of our living environment, Rats generally fall under three categories, namely, the Norway rats, the roof rats and the mouses, Among these three types, the roof rats are increasing rapidly in number and their habitats are spreading quickly in the city area, where as the Norway rats are decreasing both in number and habitat. There are numerous damages that these pests create in our society, The rat induce damages to computers and other information processing equipments, sometimes cause light-out, and other financial losses and other sanitary problems. The cockroaches, apart from inducing serious sanitary problems, is an insect that creates insectophobia. decently, it has been revealed that cockroaches are also the main carriers of allergic diseases. Among the pesticides employed against rats in Korea, Beta - fluoro acetate(1080) was initially used after the National Liberalization. Later, the Korean government imported anticoagulant rodenticide for its control. This was followed by a brief, unsuccessful utilization of Zinc Phosphide. Since the begin of 1980s, with the advent of pest control companies, first generation anticoagulant rodenticide were developed in Korea and recently followed by a widespread use of pesticide that utilizes second generation anticoagulant material, the "Brodifacoum" . Among insecticides employed against cockroaches, "Fenitrothion" "Dusban" "DDVP" "Diazinon" and others have been used. They were gradually being replaced by the use of synthesised pyrethroid insecticides until recently. Today there is a wide spread use of bait poisons, the "hydramethylnon" Nevertheless, full prevention and control can not be realized with the sole use of the pesticides. In the future, hygine and proofing, combined with affective pest management, must be incorporated in order to bring about more satisfactory and fruitful preventive measures.

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Evaluation of Anti-venom effect of Tiryaq-e-arba in rabbit models

  • Ahsan, Mohd. Tarique;Rani, Seema
    • CELLMED
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    • v.10 no.4
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    • pp.30.1-30.4
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    • 2020
  • Background: Tiryaq-e-arba is a polyherbal Unani antidote/antivenom formulation used in the management of poisoning due to snake bite, scorpion bite as well as in cold poisons since time immemorial. Objectives: Tiryaq-e-arba was not evaluated scientifically before this study carried out, therefore it was studied for antivenom activity by testing on plasma fibrinogen level in Russell's Viper envenomation in rabbits. Material &Methods: The anti-venom activity of the test drug was studied by observing its effect on plasma fibrinogen level in Russell's Viper envenomation in rabbits by the method of Netelson. Results: The plasma fibrinogen level was found to be 171±665.04 mg/100 ml of blood, 36.18±1.12 mg/100 ml of blood, 33.14±0.52 mg/100 ml of blood and 17.9±1.65 mg/100 ml of blood at 0, 1, 3 and 6 hours respectively in control animals while in the test animal it was found to be 157.13±3.44 mg/100 ml of blood, 41.13±2.69 mg/100 ml of blood, 62.09±1.65 mg/100 ml of blood and 54.39±0.73 mg/100 ml of blood respectively. The test showed that though the plasma fibrinogen level in the test lower at 0 hour but it was greater in the control animals at 1, 3 and 6 hours. The increase in plasma fibrinogen level in the test animals at 3 and 6 hours was statistically significant (P<0.001). Conclusions: The finding of the present study was that Tiryaq-e-arba possesses antivenom activity which scientifically support the Unani claim that it is Dafe-Sumoom-al-Hevan (Antivenom or Antidote) and the use of this preparation in corresponding diseases.

Yoshimasu Todo[吉益東洞]‘s medical theory extracted from ${\ulcorner}$Yakjing(藥徵)${\lrcorner}$ III ("약징(藥徵)"을 통해 본 길익동동(吉益東洞)의 의학사상 연구 III -길익동동의 의사관(醫師觀)과 의학관-)

  • Lee, Jeong-Hwan;Baik, You-Sang;Jeong, Chang-Hyun
    • Journal of Korean Medical classics
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    • v.19 no.2 s.33
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    • pp.66-73
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    • 2006
  • This study is on Yoshimasu Todo's thoughts of a real doctor and medicine. Conclusions are as below. disease-doctor[疾醫] is a doctor treating diseases by poisonous medicines. His role is different from food-doctor[食醫] who recuperates vital energy by food. Unlike food-doctor, a disease-doctor only detoxicates poisons of diseases by using poisonous medicines. Disease-doctor shall not take credit upon himself for the service of Heaven' s power. This is Yoshimasu Todo's view of a real doctor. Medicine is not an imagination, but a reality. It is the recognition of knowing what can be known and seeing what can be seen The truth of medicine is in ancient words(古語), ancient teachings[古訓] and ancient ways[古法]. To study medicine is not recklessly believing and following the contents of ancient medical texts-${\ulcorner}$Sanghanlon(傷寒論)${\lrcorner}$, ${\ulcorner}$Geumgwe-yolyag(金置要略)${\lrcorner}$,${\ulcorner}$Somun(素問)${\lrcorner}$, ${\ulcorner}$Yeongchu(靈樞)${\lrcorner}$. It is to follow the ancient ways written and left in ancient books and not to follow wrong ways fabricated by after ages. The theories of eum-yang-obaeng(陰陽五行) and o-un-yuggi(五運六氣) are useless to medicine because these are groudless ones. This is Yoshimasu Todo's view of medicine.

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Comparative Analysis of Common Herbs for Pain Related Disease between Yak-Jing and Textbook of Herbology (약징(藥徵)과 본초학 교과서의 통증 질환 관련 공통 약물에 대한 비교 분석)

  • Jeong, Jun-Kyo;Park, Won-Hyung;Cha, Yun-Yeop
    • Journal of Korean Medicine Rehabilitation
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    • v.25 no.1
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    • pp.53-61
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    • 2015
  • Objectives The purpose of this study is to compare the common herbs for pain related disease between Yak-Jing and textbook of herbology. Methods We searched the formation of "Koho" and theory of Todo yoshimasu. We selected the common herbs that is used for pain related disease in Yak-Jing and textbook of herbology. These herbs were compared with each other. Result 1. Common Herbs for pain related disease are Ephedrae Herba (麻黃), Aconiti Lateralis Preparata Radix (附子), Euphorbiae Kansui Radix (甘遂), Euphorbiae pekinensis Radix (大戟) Daphnis Genkwa Flos (芫花), Atractylodis Rhizoma (朮), Paeonia Radix Rubra (芍藥), JujubaeFructus (大棗), Gypsum (石膏), Anemarrhenae Rhizoma (知母), Cinnamomi Ramulus (桂枝), Poria (茯苓), Rhei Rhizoma (大黃), Natrii Sulfas (芒草), Pueraiae Radix (葛根). There are some difference between textbook of herbology and Yak-Jing about Aconiti Lateralis Preparata Radix (附子), Paeonia Radix Rubra (芍藥), Atractylodis Rhizoma (蒼朮), Pueraiae Radix (葛根). 2. Preparata Radix (附子) excrete water poisons (水毒) in Yak-Jing, but it has the effect of restore yang and tonify fire (回陽補火) in textbook of herbology. 3. Paeonia Radix Rubra (芍藥) is effective for pathological condition caused by the formation of the band and spasm (結實拘攣) in Yak-Jing, but it is to cure heat pattern in textbook of herbology. 4. Atractylodis Rhizoma (蒼朮) has the effect of water-draining (利水) in Yak-Jing, but it has the effect of dispersing (發散) in textbook of herbology. 5. Pueraiae Radix (葛根) is used in dyspnea and sweating (喘而汗出) in Yak-Jing, but it is to cure engender fluid (生津), skin disease, diarrhea in textbook of herbology. Conclusion There are some difference between textbook of herbology and Yak-Jing in the herb medicine that is used in pain related disease.