• 의료법학
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• 제11권1호
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• pp.271-296
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• 2010

Objective: Poisonous Medicinal herbs can be considered as a risk factor to public health unless they are prescribed by Doctor of traditional Korean medicine. The proper method to manage them should be prepared to prevent risk factors caused by misuse and abuse of the poisonous medicinal herbs and enhance public health. Methods: In this dissertation (paper), the definition, scope, management status, data about pharmacology and toxicity and media release regarding adverse reaction were understood after organizing documents, laws and regulations concerning poisonous medicinal herbs. Also, management methods are suggested by analyzing related examples and regulations in China, Japan and Hong Kong, where the use of herbal medicine is general. Results: Methods for items for poisonous medicinal herbs, safety information management, management based on standardization of traditional processing methodology and reorganization and revision of related laws and regulations are established. Conclusion: Proper laws and regulations are not yet established to manage poisonous medicinal herbs in Korea. In this regard, it is urgent to establish laws and regulations which can apply independently. The purpose of the laws and regulations should be to enhance management of poisonous medicinal herbs and prevent incidence of addiction and death, improving the public health.

• 한국자원식물학회:학술대회논문집
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• 한국자원식물학회 2003년도 제10차 국제학술회의 및 추계정기 학술발표회
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• pp.1-1
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• 2003

Poisonous mushrooms have attracted much attention of scientists because of the unique chemical structures and the remarkable biological properties of their toxic components. A wide range of compounds has been characterized as toxic principles, and some of them have widened the horizons of chemical and biological research. Therefore, poisonous mushrooms can serve for a resource of biomedical application. We will describe the recent progress of such aspect of poisonous mushrooms.

• 한국자원식물학회:학술대회논문집
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• 한국자원식물학회 2003년도 심포지엄
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• pp.1-8
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• 2003

Poisonous mushrooms have attracted much attention of scientists because of the unique chemical structures and the remarkable biological properties of their toxic components. A wide range of compounds has been characterized as toxic principles, and some of them have widened the horizons of chemical and biological research. Therefore, poisonous mushrooms can serve for a resource of biomedical application. We will describe the recent progress of such aspect of poisonous mushrooms.

• 한국환경보건학회지
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• 제41권6호
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• pp.380-388
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• 2015

Objectives: Poisonous substances experts engage in policymaking regarding poisonous substances, whereas poisonous substances managers perform legal duties related to poisonous substances management systems at worksites. To understand and improve poisonous substances designation systems, it is necessary to distinguish the roles of these experts and managers. We further aimed to identify problems with poisonous substances appointment systems and provide basic data for their improvement by investigating the knowledge and recognition of the need for system improvement among managers and experts. Methods: To determine the $subjects^{\circ}{\emptyset}$ awareness of poisonous substances designation systems, a selfadministered questionnaire comprised of items on general characteristics and knowledge and recognition of the need for system improvement was issued. Data were analyzed via t-tests and ANOVA using SPSS v 16.0 Results: Regarding system comprehension, managers (n=213; mean 3.28, SD 0.63) significantly differed from experts (n=35; mean 4.08, SD 0.59) (P<0.001). No differences were found in recognition of need for improvement between managers (mean 3.11, SD 0.34) and experts (mean 3.24, SD 0.31). Significant differences in comprehension were found among managers by education level (P<0.05) and company size (P<0.05). Regarding industry type, comprehension was greater in the electrical/electronic and chemical/environmental industries compared to in other industries (P = 0.066). Comprehension was higher among those with five years or more of experience compared to those with less than five years. Regarding recognition of need for improvement, managers showed significant differences by company size (P<0.05). $Experts^{\circ}{\emptyset}$ comprehension showed no differences by general characteristics, while need for improvement differed according to work experience (P<0.001). Conclusion: The study found that the bigger the company size, the higher the level of comprehension by managers and the experts. In the case of both groups, where a higher comprehension of the poisonous substances designation system was evident, they recognized the necessity of its improvement.

• 한국산업보건학회지
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• 제23권2호
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• pp.156-163
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• 2013

Objectives: Numerous poisonous substances are used in paint manufacture, but there are differences in the results of GHS classification between the Ministry of Labor(MOL) and the Ministry of Environment(MOE). Therefore, paint manufacturers suffer confusion as to how to classify a given chemical's risk and hazard level. This paper was designed to compare the classification results of chemicals by the MOL and the MOE and suggest a harmonization measure. Methods: After selecting 25 poisonous substances from among the organic solvents, pigments, and additives used in paint manufacturer, the GHS classification results by MOL and MOE were compared. Further the logic and classification of the GHS proposed by each Ministry was analyzed. Based on the derived results, a harmonization plan was proposed. Results: Based on the GHS classification of the poisonous substances, the concordance is 10.0-66.6 %, excluded flammable liquid. The GHS classifications differed based on the suggested building blocks, the sub-classification method used, the references(data sources), and subjective judgment of the experts from each Ministry. In order to pursue the harmonization plan, cooperation is demanded from the MOL and MOE.

• Toxicological Research
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• 제2권2호
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• pp.51-62
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• 1986

Of mushrooms found in Japan, approximately 35 species are classified as poisonous mushrooms. The mushroom poisonings caused by these mushrooms are classified as three types accodring to the symptoms and their toxic constitutents. The first type is the cholera-like symptom which is induced mainly by the toxic constitutents such as cyclopeptide and gyromitrin. The second type is the neurological mainfestations induced by muscarine (cholinergic), muscimol (delirium), psilocybin (hallucinogenic) and coprine (antabuse-like).

• 대한수의학회지
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• 제18권1호
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• pp.39-50
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• 1978

Because of very little information available regarding the poisonous plants distributed in Jeju-Island, the author made a survey of such plants from March, 1974 to Dec., 1977. The results obtained were as follows: 1. If not all, 68 families, 137 genera and 190 species of poisonous plants distributed in Jeju-island were classified. And 190 species were divided into 137 spp. of herbs, 45 spp. of shrubs, 3 spp. of molds and 5 spp. of toadstools. 2. Relatively, a large number of poisonous plants were distributed in wild field. Jungle area, inhabited region, seashore and high mountainous area took next place gradually by the number of plants. 3. And according to their toxic chemical components or poisoning types, they were classified as 16 spp. of cyanogenetic plants, 14 spp. of oxalate-producing plants, 14 spp. of nitrate. producing plants, 10 spp. of photosensitization and 136 spp. of the other activities.

• Journal of Forest and Environmental Science
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• 제26권1호
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• pp.37-51
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• 2010

A mushroom as a functional food material is being increasingly used in these days. It has been that about 1,500 species of mushrooms grow naturally in Asia. Among them about 700 species are edible, but about 30-50 species are poisonous. Even a poisonous mushroom is a very interesting subject for the dietary life research from biochemical viewpoint due to the fact that any mushroom can be the physiological active material. Not a few identified poisonous materials are being used as research reagents thus far. It is suggested that more useful materials could be obtained by progresses in future researches. The identification of the poisonous ingredient can open up a route for mushroom intoxication cure. It is known that cell destruction and troubles on skin, liver, and kidney troubles can be occurred from mushroom intoxication. Recently the author reported as a collection of treatises regarding anti-tumor substances of mushroom (2005), antibiotic substances of mushroom (2006), living-body functional and control substance (2007), and medicinal mushroom commonly used in Korean herbal medicines (2008). In this sequel, published research data on protoplasm, nerve, stomach and intestines, malodor, and acute pain poison of mushroom are collected and reported.

• 한국환경생태학회지
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• 제31권2호
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• pp.230-251
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• 2017

2009년부터 2011년, 2015년까지 변산반도 국립공원의 고등균류를 조사한 결과, 총 2문 6강 18목 61과 157속 323종이 조사 되었으며, 주름버섯목(Agaricales)이 23과 67속 153종, 그물버섯목(Boletales) 6과 27속 45종, 무당버섯목(Russulales) 3과 4속 40종 및 구멍장이버섯목(Polyporales) 6과 21속 28종으로 4목의 종수가 총 266종으로 전체 종수의 82.4%로 대부분을 차지한 것으로 나타났다. 가장 많은 종수가 조사된 균류는 그물버섯과로 37종이었으며, 무당버섯과(36종), 주름버섯과(28종) 및 광대버섯과(25종) 순으로 우점하고 있는 것으로 나타났다. 서식환경별에서는 외생균근성 버섯은 15과 38속 130종(40.2%)으로 독성 버섯은 46종, 식 약용 버섯 51종 및 식 독 불명 버섯 26종 등이 조사되었으며 낙엽 및 목재부후균은 33과 72속 114종(35.3%)이었고 이 중 독성 버섯은 10종, 식 약용 버섯 52종 및 식 독 불명 버섯 46종 등이, 지상균은 24과 47속 72종(22.3%)이었고 독성 버섯은 8종, 식 약용 버섯 31종 및 식 독 불명 버섯 29종 등인 것으로 나타났다. 월별 발생에서는 대부분의 독성 버섯, 식 약용 버섯 및 식 독 불명 버섯 등은 7월과 8월에 집중적으로 발생하는 것으로 나타났다. 고도별에서는 대부분의 독성 버섯, 식 약용 버섯 및 식 독 불명 버섯 등은 1~199m 지역에서 많이 발생되고 있는 것으로 나타났으며 200m 이상 지역에서는 현저히 낮아지는 것으로 조사되었다. 독성 버섯, 식 약용 버섯 및 식 독 불명 버섯 등은 평균온도에서는 $24.0{\sim}25.9^{\circ}C$, 최고온도 $28.0{\sim}29.9^{\circ}C$, 최저온도 $20.0{\sim}21.9^{\circ}C$, 상대습도 77.0~79.9% 및 강수량 300.0~499.9mm일 때 발생이 높은 것으로 나타났다.

• 한국자원식물학회지
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• 제35권2호
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• pp.346-361
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• 2022

독성 식물로 인한 식중독 사고는 매년 발생하고 있으며, 일부 독성 식물은 식용 식물로 오인 섭취되어 식중독을 유발하기 때문에 독성 식물의 정확한 종 식별이 요구되고 있다. 이러한 요구에 따라 감정기관에서는 독성 식물의 종 식별에 적합한 DNA 바코드를 찾아 신속하고 정확한 종 식별에 활용할 수 있는 데이터베이스를 구축하는 것이 필요한 실정이다. 따라서 본 연구는 다양한 독성 식물에서 DNA 바코드 구간의 염기서열을 확보하고, 각각에 적합한 DNA 바코드를 확인하여 데이터베이스를 구축하고자 하였으며, 기초 연구로써 제주도에 자생하는 독성식물 19종을 선정하여 7개의 DNA 바코드 (trnH-psbA, trnL-trnF, trnL intron, rbcL, matK, ITS1-ITS4, 18S rRNA)를 이용한 종식별을 수행하였다. 종 식별 결과 trnL-trnF 바코드와 ITS1-ITS4 바코드가 PCR 증폭 및 염기서열 획득에 가장 용이하였으며, 두 개의 바코드를 조합하여 사용하면 19종 중 18종의 식물에서 단일 종 식별이 가능하였다. 따라서 미지의 독성 식물에 대한 감정이 의뢰되었을 때 trnL-trnF 바코드와 ITS1-ITS4 바코드를 조합하여 사용하면 신속한 종 식별에 도움이 될 것으로 사료된다. 본 연구에서 제시된 독성식물 19종의 염기서열 및 DNA 바코드 데이터베이스는 더욱 신속하고 정확한 독성 식물의 종 식별 감정에 도움이 될 것이다.