• Title/Summary/Keyword: Poisonous

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Study on The Regulation on Poisonous Medicinal Herbs (독성 한약재의 법적 규제에 관한 연구)

  • Kweon, Kee-Tae
    • The Korean Society of Law and Medicine
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    • v.11 no.1
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    • pp.271-296
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    • 2010
  • Objective: Poisonous Medicinal herbs can be considered as a risk factor to public health unless they are prescribed by Doctor of traditional Korean medicine. The proper method to manage them should be prepared to prevent risk factors caused by misuse and abuse of the poisonous medicinal herbs and enhance public health. Methods: In this dissertation (paper), the definition, scope, management status, data about pharmacology and toxicity and media release regarding adverse reaction were understood after organizing documents, laws and regulations concerning poisonous medicinal herbs. Also, management methods are suggested by analyzing related examples and regulations in China, Japan and Hong Kong, where the use of herbal medicine is general. Results: Methods for items for poisonous medicinal herbs, safety information management, management based on standardization of traditional processing methodology and reorganization and revision of related laws and regulations are established. Conclusion: Proper laws and regulations are not yet established to manage poisonous medicinal herbs in Korea. In this regard, it is urgent to establish laws and regulations which can apply independently. The purpose of the laws and regulations should be to enhance management of poisonous medicinal herbs and prevent incidence of addiction and death, improving the public health.

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Poisonous mushrooms as a resource of biomedical application

  • Katsuhiro Konno;Kim, iko-Hashimoto;Haruhisa Shirahama
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2003.10b
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    • pp.1-1
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    • 2003
  • Poisonous mushrooms have attracted much attention of scientists because of the unique chemical structures and the remarkable biological properties of their toxic components. A wide range of compounds has been characterized as toxic principles, and some of them have widened the horizons of chemical and biological research. Therefore, poisonous mushrooms can serve for a resource of biomedical application. We will describe the recent progress of such aspect of poisonous mushrooms.

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Poisonous mushrooms as a resource of biomedical application

  • Katsuhiro Konno;Kim, iko-Hashimoto;Haruhisa Shirahama
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2003.10a
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    • pp.1-8
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    • 2003
  • Poisonous mushrooms have attracted much attention of scientists because of the unique chemical structures and the remarkable biological properties of their toxic components. A wide range of compounds has been characterized as toxic principles, and some of them have widened the horizons of chemical and biological research. Therefore, poisonous mushrooms can serve for a resource of biomedical application. We will describe the recent progress of such aspect of poisonous mushrooms.

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An Analysis of the Gap in Recognition between Managers and Experts regarding the Poisonous Substances Designation System (유독물지정제도에 대한 유해화학물질관리자 및 전문가의 인식도 분석 연구)

  • Kim, Mi Na;Lee, Seung Kil;Doo, Yong Kyoon;Cho, Sam Rae;Choi, Jae-Wook
    • Journal of Environmental Health Sciences
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    • v.41 no.6
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    • pp.380-388
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    • 2015
  • Objectives: Poisonous substances experts engage in policymaking regarding poisonous substances, whereas poisonous substances managers perform legal duties related to poisonous substances management systems at worksites. To understand and improve poisonous substances designation systems, it is necessary to distinguish the roles of these experts and managers. We further aimed to identify problems with poisonous substances appointment systems and provide basic data for their improvement by investigating the knowledge and recognition of the need for system improvement among managers and experts. Methods: To determine the $subjects^{\circ}{\emptyset}$ awareness of poisonous substances designation systems, a selfadministered questionnaire comprised of items on general characteristics and knowledge and recognition of the need for system improvement was issued. Data were analyzed via t-tests and ANOVA using SPSS v 16.0 Results: Regarding system comprehension, managers (n=213; mean 3.28, SD 0.63) significantly differed from experts (n=35; mean 4.08, SD 0.59) (P<0.001). No differences were found in recognition of need for improvement between managers (mean 3.11, SD 0.34) and experts (mean 3.24, SD 0.31). Significant differences in comprehension were found among managers by education level (P<0.05) and company size (P<0.05). Regarding industry type, comprehension was greater in the electrical/electronic and chemical/environmental industries compared to in other industries (P = 0.066). Comprehension was higher among those with five years or more of experience compared to those with less than five years. Regarding recognition of need for improvement, managers showed significant differences by company size (P<0.05). $Experts^{\circ}{\emptyset}$ comprehension showed no differences by general characteristics, while need for improvement differed according to work experience (P<0.001). Conclusion: The study found that the bigger the company size, the higher the level of comprehension by managers and the experts. In the case of both groups, where a higher comprehension of the poisonous substances designation system was evident, they recognized the necessity of its improvement.

A Study on the Harmonization of Poisonous Substance Used in Paint Manufacture (도료제조업종에서 취급하는 유독물의 GHS 분류 통일화 방안 연구)

  • Lee, Jong Han;Hong, Mun Ki;Kim, Hyun Ji;Park, Sang Hee
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.23 no.2
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    • pp.156-163
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    • 2013
  • Objectives: Numerous poisonous substances are used in paint manufacture, but there are differences in the results of GHS classification between the Ministry of Labor(MOL) and the Ministry of Environment(MOE). Therefore, paint manufacturers suffer confusion as to how to classify a given chemical's risk and hazard level. This paper was designed to compare the classification results of chemicals by the MOL and the MOE and suggest a harmonization measure. Methods: After selecting 25 poisonous substances from among the organic solvents, pigments, and additives used in paint manufacturer, the GHS classification results by MOL and MOE were compared. Further the logic and classification of the GHS proposed by each Ministry was analyzed. Based on the derived results, a harmonization plan was proposed. Results: Based on the GHS classification of the poisonous substances, the concordance is 10.0-66.6 %, excluded flammable liquid. The GHS classifications differed based on the suggested building blocks, the sub-classification method used, the references(data sources), and subjective judgment of the experts from each Ministry. In order to pursue the harmonization plan, cooperation is demanded from the MOL and MOE.

THE POISONOUS MUSHROOMS IN JAPAN

  • Yamaura, Yoshio;Yokoyama, Kazumasa
    • Toxicological Research
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    • v.2 no.2
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    • pp.51-62
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    • 1986
  • Of mushrooms found in Japan, approximately 35 species are classified as poisonous mushrooms. The mushroom poisonings caused by these mushrooms are classified as three types accodring to the symptoms and their toxic constitutents. The first type is the cholera-like symptom which is induced mainly by the toxic constitutents such as cyclopeptide and gyromitrin. The second type is the neurological mainfestations induced by muscarine (cholinergic), muscimol (delirium), psilocybin (hallucinogenic) and coprine (antabuse-like).

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Survey of Poisonous Plants Distributed in Jeju-Island (제주도(濟州道)의 유독식물(有毒植物)에 대(對)한 조사연구(調査硏究))

  • Yang, Kichun
    • Korean Journal of Veterinary Research
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    • v.18 no.1
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    • pp.39-50
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    • 1978
  • Because of very little information available regarding the poisonous plants distributed in Jeju-Island, the author made a survey of such plants from March, 1974 to Dec., 1977. The results obtained were as follows: 1. If not all, 68 families, 137 genera and 190 species of poisonous plants distributed in Jeju-island were classified. And 190 species were divided into 137 spp. of herbs, 45 spp. of shrubs, 3 spp. of molds and 5 spp. of toadstools. 2. Relatively, a large number of poisonous plants were distributed in wild field. Jungle area, inhabited region, seashore and high mountainous area took next place gradually by the number of plants. 3. And according to their toxic chemical components or poisoning types, they were classified as 16 spp. of cyanogenetic plants, 14 spp. of oxalate-producing plants, 14 spp. of nitrate. producing plants, 10 spp. of photosensitization and 136 spp. of the other activities.

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Poisonous Substances from Mushrooms (버섯의 유독물질 (有毒物質))

  • Cho, Jae-Hyun;Lee, Tae-Seong;Kim, Bo-Min;Hwang, Byang-Ho
    • Journal of Forest and Environmental Science
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    • v.26 no.1
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    • pp.37-51
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    • 2010
  • A mushroom as a functional food material is being increasingly used in these days. It has been that about 1,500 species of mushrooms grow naturally in Asia. Among them about 700 species are edible, but about 30-50 species are poisonous. Even a poisonous mushroom is a very interesting subject for the dietary life research from biochemical viewpoint due to the fact that any mushroom can be the physiological active material. Not a few identified poisonous materials are being used as research reagents thus far. It is suggested that more useful materials could be obtained by progresses in future researches. The identification of the poisonous ingredient can open up a route for mushroom intoxication cure. It is known that cell destruction and troubles on skin, liver, and kidney troubles can be occurred from mushroom intoxication. Recently the author reported as a collection of treatises regarding anti-tumor substances of mushroom (2005), antibiotic substances of mushroom (2006), living-body functional and control substance (2007), and medicinal mushroom commonly used in Korean herbal medicines (2008). In this sequel, published research data on protoplasm, nerve, stomach and intestines, malodor, and acute pain poison of mushroom are collected and reported.

Resources Use Characteristics of Higher Fungi in Byeonsanbando National Park (변산반도 국립공원 고등균류의 자원이용적 특성)

  • Jang, Seog-Ki
    • Korean Journal of Environment and Ecology
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    • v.31 no.2
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    • pp.230-251
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    • 2017
  • According to the survey on higher fungi from 2009 to 2011 and also in 2015 in Byeonsanbando National Park, a total of 2 division, 6 class, 18 orders, 61 families, 157 genera and 323 species were observed. In case of Agaricales, there were 23 families, 67 genera and 153 species; Boletales, there were 6 families, 27 genera and 45 species; Russulales, there were 3 family, 4 genera and 40 species; Polyporales, there were 6 family, 21 genera, 28 species. Thus, most of them belonged to the following 4 orders: Agaricales, Russulales, Boletales and Polyporales. Dominant species belonged to Boletaceae (37 species), Russulaceae (36 species), Agaricaceae (28 species) and Amamtaceae (25 species). For the habitat environment, the ectomycorrhizal mushrooms were 40.2% (poisonous mushrooms, 46 species; edible & medicinal mushrooms, 51 species; unknown edible & poisonous mushrooms, 26 species), litter decomposing and wood rotting fungi 35.3%(poisonous mushrooms, 10 species; edible & medicinal mushrooms, 52 species; unknown edible & poisonous mushrooms, 46species), grounding Fungi 22.3%(poisonous mushrooms, 8 species; edible & medicinal mushrooms, 31 species; unknown edible & poisonous mushrooms, 29 species). Monthly, most of poisonous mushrooms, edible & medicinal mushrooms and unknown edible & poisonous mushrooms were found in July and August. In terms of altitude, the most species were observed at 1~99m and the populations dropped by a significant level at an altitude of 200m or higher. It seemed that the most diversified poisonous mushrooms, edible & medicinal mushrooms and unknown edible & poisonous mushrooms occurred at climate conditions with a mean air temperature at $24.0{\sim}25.9^{\circ}C$, the highest air temperature at $28.0{\sim}29.9^{\circ}C$, the lowest air temperature at $20.0{\sim}21.9^{\circ}C$, a relative humidity at 77.0~79.9% and a rainfall of 300.0~499.9mm.

Identification of 19 Species of Poisonous Plants from Jeju Island and Construction of a Database Using DNA-barcoding (DNA-barcoding을 이용한 제주도 자생 독성 식물 19종의 종 식별 및 데이터베이스 구축)

  • Kwon, Eunchae;Kim, Joo-Young;Chang, Miwha;Lee, Minji;Moon, Seohyun;Lee, Won-Hae
    • Korean Journal of Plant Resources
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    • v.35 no.2
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    • pp.346-361
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    • 2022
  • Food poisoning accidents caused by poisonous plants occur every year. As certain poisonous plants are mistaken for edible plants causing food poisoning, accurate species identification of poisonous plants is required. DNA barcodes suitable for species identification of poisonous plants and database that can be used for accurate species identification are necessary for their use in forensic cases. In this study, species identification of 19 poisonous plants native to Jeju Island using seven DNA barcodes (trnH-psbA, trnL-trnF, trnL intron, rbcL, matK, ITS1-ITS4, 18S rRNA) was performed to construct a database containing sequence information and DNA barcode universality. trnL-trnF barcode and ITS1-ITS4 barcode were the easiest markers for PCR amplification and sequence retrieval, and the combination of the two barcodes enabled single species identification in 18 out of 19 plants. Therefore, when an investigation of unknown poisonous plants is requested, combination of trnL-trnF and ITS1-ITS4 barcodes is considered as a primary marker for species identification. The database of recommended DNA barcodes for each poisonous plant presented in this study will be helpful in plants poisoning cases.