• 한국보육지원학회지
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• 제11권5호
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• pp.191-214
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• 2015

본 연구에서는 유아의 기질, 부모의 양육방식, 교사-유아 상호작용이 또래상호작용에 미치는 영향을 조사하고자 하였다. 분석을 위해 육아정책연구소의 한국아동패널의 5차년도(2012) 데이터 중 996명의 4세 유아 자료를 t 검증, 일원변량분석, 적률상관분석, 중다회귀분석하였다. 결과는 다음과 같다. 첫째, 유아의 기질 중 사회성과 활동성이 높을수록, 교사의 긍정적 상호작용이 적을수록 놀이방해를 많이 하였다. 둘째, 유아의 사회성기질이 강할수록 교사가 긍정적인 상호작용을 많이 할수록 놀이상호작용이 많이 나타났다. 여아는 어머니가 통제적 양육을 많이 할수록 놀이상호작용을 많이 하였다. 셋째, 유아의 정서성기질이 강할수록, 사회성기질이 약할수록 교사의 긍정적 상호작용이 적을수록 놀이단절을 많이 하였다. 남아는 아버지가 사회적 양육을 적게 할수록 놀이단절을 많이 하였다. 넷째, 교사-유아 상호작용이 유아의 또래상호작용에 가장 강력한 영향을 미치는 변인이었으며 그 다음 유아기질의 영향력이 큰 것으로 나타났다. 본 연구의 결과는 유아의 또래상호작용의 증진을 위한 교사역할의 중요성을 시사하고 있다.

• 한국산학기술학회논문지
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• 제22권4호
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• pp.255-262
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• 2021

본 연구는 숲체험 놀이에서 밧줄 놀이가 유아 자신감에 미치는 효과를 분석하는 데 있다. 이를 위해 실험집단 15명(남아7명, 여아8명)과 비실험집단 15명(남아9명, 여아6명)을 대상으로 실험설계를 통한 실증분석하였다. 실험처치를 하고 실험집단 및 통제집단 간 효과를 검정하기 위해 공분산분석(ANCOVA)을 실시한 결과, 실험집단의 평균이 통제집단의 평균보다 통계적으로 의미있게 높은 것으로 나타났다(F=357.350, p<.001). 이같은 결과는 숲체험 밧줄 놀이를 통해 유아의 자신감에 미치는 효과가 통계적으로 의미 있는 효과를 나타낸 것으로 평가할 수 있다. 이는 또래 간 숲체험 밧줄 놀이가 유아의 자신감 향상에 보다 긍정적인 효과를 나타내주는 유익한 놀이로 유아들의 숲체험 놀이를 통해 또래 간 협력을 통한 상호작용 속에 감정과 충동조절로 소극적 성격의 유아의 자신감을 높여주는 긍정적인 놀이활동임을 확인시켜준 것으로 판단할 수 있다.

• 농업과학연구
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• 제39권2호
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• pp.189-194
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• 2012

It is well-known fact that woodworking activity could contribute in enhancing creativity, scientific problem-solving ability, spatial perception ability and prosocial behavior of children. However, there is little chance that children experience woodworking at home or in kindergarten. This study was conducted to know how much children and adults have done woodworking in there daily life and how they perceived children's woodworking activity. Woodworking activities for children (N=207, 5 and 6 year old kids) with adults (N=271, only fathers) were carried out in 10 kindergartens of Cheongju. Actually, the survey result shows that very few children and adults experienced woodworking in their daily life. 62.8% of children and 34.3% of adults surveyed responded that they had never done woodworking. However, the greater part of children and adults evaluated the woodworking activity positively. Over 95% of children surveyed responded that their woodworking activity was fun and they want to play woodworking again. Over 73% of adults surveyed responded that children's woodworking activity was safe, and over 99% of adults surveyed responded that they can recommend children's woodworking activity to others. In conclusion, the development of safe tools and programs for children's woodworking activity helps its spread and activation.

• 대한치과교정학회지
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• 제25권6호
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• pp.689-696
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• 1995

Effects of several cytokines($IL-1{\beta},\;TNF_{\alpha},\;and\;IFN_{\gamma}$) have been examined on fetal rat osteoblast-like cells. To investigate whether cytokines play direct causal roles in production of lysosomal enzyme, fetal rat osteoblast-like cells were treated with $IL-1{\beta},\;TNF_{\alpha},\;and\;IFN_{\gamma}$, respectively or combined. And acid phosphatase was determined by biochemical method. Alkaline phosphatase was assayed to determine the effects of $IL-1{\beta},\;TNF_{\alpha},\;and\;IFN_{\gamma}$ on the expression of this enzyme. And also experiment of calcified nodule formation was performed to assess the effects of cytokines on the bone-forming activity of osteoblast-like cells in vitro. Acid phosphatase activity was significantly increased by the addition of $IL-1{\beta}\;and\;TNF_{\alpha}$, whereas decreased by $IFN_{\gamma}$. However, no significant change:: in alkaline phosphatase activity was observed when the osteoblast-like cells were treated with $IL-1{\beta}\;and\;TNF_{\alpha}$. Interestingly, $IFN_{\gamma}$ showed stimulatory effect on alkaline phosphatase activity. The number of calcified nodules was decreased by treatment of cultures with 1 ng/ml $IL-1{\beta},\;20\;ng/ml\;TNF_{\alpha}$, and 500 u/ml $IFN_{\gamma}$ continuously for 21 days, while considerable number of calcified nodules were formed in control group of osteoblast-like cell in culture for 21 days. These results seem to suggest that cytokines may play crucial roles in bone remodeling through the direct action on the osteoblast-like cell.

• 생약학회지
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• 제31권2호
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• pp.228-234
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• 2000

Effects of Houttuynia cordata on the level of lipid peroxide and the enzyme activities of the liver were investigated in bromobenzene-induced rats. Lipid peroxide content in liver was increased by bromobenzene. It was decreased when the methanol extract from the aerial parts of H. cordata was treated to the rat. The methanol extract reduced the activities of aminopyrine N-demethylase and aniline hydroxylase that increased by bromobenzene, however did not affect glutathione S-transferase activity. The methanol extract recovered the activity of epoxide hydrolase activity that decreased significantly by bromobenzene. We suggest that under our experimental conditions the extract might play an important play in the prevention of hepatotoxicity by reduction of aminopyrine N-demethylase and aniline hydroxylase activities as well as enhancement of epoxide hydrolase activity. Six phenolic compounds have been isolated from H. cordata and identified by means of spectral analysis as protocatechuic acid, quercetin, apigenin, afzelin, hyperoside and quercitrin.

• Genes and Genomics
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• 제40권11호
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• pp.1199-1211
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• 2018

Soil acidification is one of major problems limiting crop growth and especially becoming increasingly serious in China owing to excessive use of nitrogen fertilizer. Only the STOP1 of Arabidopsis was identified clearly sensitive to proton rhizotoxicity and the molecular mechanism for proton toxicity tolerance of plants is still poorly understood. The main objective of this study was to investigate the transcriptomic change in plants under the low pH stress. The low pH as a single factor was employed to induce the response of the wheat seedling roots. Wheat cDNA microarray was used to identify differentially expressed genes (DEGs). A total of 1057 DEGs were identified, of which 761 genes were up-regulated and 296 were down-regulated. The greater percentage of up-regulated genes involved in developmental processes, immune system processes, multi-organism processes, positive regulation of biological processes and metabolic processes of the biological processes. The more proportion of down-regulation genes belong to the molecular function category including transporter activity, antioxidant activity and molecular transducer activity and to the extracellular region of the cellular components category. Moreover, most genes among 41 genes involved in ion binding, 17 WAKY transcription factor genes and 17 genes related to transport activity were up-regulated. KEGG analysis showed that the jasmonate signal transduction and flavonoid biosynthesis might play important roles in response to the low pH stress in wheat seedling roots. Based on the data, it is can be deduced that WRKY transcription factors might play a critical role in the transcriptional regulation, and the alkalifying of the rhizosphere might be the earliest response process to low pH stress in wheat seedling roots. These results provide a basis to reveal the molecular mechanism of proton toxicity tolerance in plants.

• 한국콘텐츠학회논문지
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• 제7권3호
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• pp.101-109
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• 2007

한국과학 영재학교 학생들과 민족사관고 학생들의 여가활동 실태를 규명하기 위하여 영재학교 166명 (남:122, 여:44), 민사고 184명(남:71, 여:113)을 대상으로 분석하였다. 1) 남학생들은 스포츠에 여학생의 경우 영재학교는 취미교양 활동에 민사고는 관람 감상활동에 가장 많이 참여하는 것으로 나타났다. 2) 여가활동을 하게 된 직접적인 동기는 정신적 스트레스와 갈등 해소라는 응답이 가장 많았고, $75\sim80%$정도가 여가활동이 건강과 체력 유지에 아주 중요한 역할을 하는 것으로 인식하고 있었다. 3) 혼자서 여가 활동을 한다는 비율이 30%정도였고, 계획 없이 여가활동을 실시한다는 응답도 영재학교 남학생 51%, 여학생 40%, 민사고는 남학생 40%, 여학생 48% 정도인 것으로 제시되었다. 4) 평일에 주로 영재학교 남학생들은 스포츠 활동에 참여하였고, 민사고 남 여학생 및 영재학교 여학생 집단은 취미 교양활동에 가장 많이 참여하였다. 5) 남학생의 경우 영재학교 38%, 민사고기 54% 학생들이 평일에 컴퓨터 게임을 하지 않는다고 응답하였고, 여학생은 70% 정도가 컴퓨터 게임을 하지 않는 것으로 나타났다. 영재학교 남학생들이 민사고 남학생들 보다 컴퓨터 게임에 더 많은 시간을 소비하였다. 6) 여가 활동을 하지 않는 가장 큰 이유로 시험이나 과제로 인한 시간부족을 꼽았고, 게을러서 여가 활동을 하지 않는다는 응답도 $19\sim25%$나 되었다.

• 한국경영정보학회:학술대회논문집
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• 한국경영정보학회 2007년도 추계학술대회
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• pp.123-128
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• 2007

It has been argued that Enterprise systems (ES) implementations are overshadowed by a high failure rate despite their promised benefits. One of the commonly cited reasons for ES implementation failures in the context of mandatory use is end-user's unwillingness or sabotage to adopt or use systems. Considering that the appropriate management of expectations may play an important role in making positive behavior toward newly implemented systems, this study examines the effect of outcome expectations on the system use activity in the mandatory use context of information systems from the Social Cognitive Theory perspective. Structural equation model analysis using LISREL 8.7 provides significant support for the proposed relationships. The empirical results suggest that outcome expectations and user satisfaction have positive effects on system use activity conceptualized by immersion, reinvention, and learning. Theoretical and practical implications of the study shed some light on how to improve system use activity in the mandatory use context of information systems.

• 한국미생물·생명공학회지
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• 제29권1호
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• pp.56-61
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• 2001

For the development of probiotics in aquaculture of marine organisms, three strains having psychrophilic and salt tolerant characteristics were isolated from Kimchi. Amng the isolated strains. MG19, MG89 and MG208 were identified as Lactobacillus brevis, Enterococcus faecium and Lactobacillus plantarum, respectively. The neutralized culture broth of isolated strains were tested in order to evaluate the antibactrial activity, 조초 showed high antibacterial activity against Edwardsiella tarda, Vibrio cholerae andPseudomonas fluorescens. In mixed culture of pathogens and isolated strain,pathogens were signifi-cantly inhibited after 2 days of cultivation but the isolated strains showed normal growth. When the Edwardsiella tarda was cultured with three isolated strains, its growth was completely inhibited after 254 hours of cultivation. The effect of isolated three strains as probiotics was investigated based on the changes in body weight of aquacultured flounder. After 50 days feeding trial, it was found that the mean body weight gain of the tested group fed freeze-dried isolated cells was significantly greater than that of the control group. These results suggest that these isolated strains can play an important role as probiotics in aquaculture.

• 통합자연과학논문집
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• 제8권2호
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• pp.81-88
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• 2015

c-Jun N-terminal kinase-3 (JNK3) is a member of the mitogen-activated protein kinase family (MAPK), and plays an important role in neurological disorders. Therefore, identification of selective JNK3 inhibitor may contribute towards neuroprotection therapies. In this work, we performed hologram quantitative structure-activity relationship (HQSAR) on a series of thiophene trisubstituted derivatives. The best predictions were obtained for HQSAR model with $q^2=0.628$ and $r^2=0.986$. Statistical parameters from the generated QSAR models indicated the data is well fitted and have high predictive ability. HQSAR result showed that atom, bond and chirality descriptors play an important role in JNK3 activity and also shows that electronegative groups is highly favourble to enhance the biological activity. Our results could be useful to design novel and selective JNK3 inhibitors.