• Nuclear Engineering and Technology
• /
• v.48 no.5
• /
• pp.1184-1191
• /
• 2016

This paper introduces the development of a transient monitoring system to detect the early stage of a transient, to identify the type of the transient scenario, and to inform an operator with the remaining time to turbine trip when there is no operator's relevant control. This study focused on the transients originating from a secondary system in nuclear power plants (NPPs), because the secondary system was recognized to be a more dominant factor to make unplanned turbine-generator trips which can ultimately result in reactor trips. In order to make the proposed methodology practical forward, all the transient scenarios registered in a simulator of a 1,000 MWe pressurized water reactor were archived in the transient pattern database. The transient patterns show plant behavior until turbine-generator trip when there is no operator's intervention. Meanwhile, the operating data periodically captured from a plant computer is compared with an individual transient pattern in the database and a highly matched section among the transient patterns enables isolation of the type of transient and prediction of the expected remaining time to trip. The transient pattern database consists of hundreds of variables, so it is difficult to speedily compare patterns and to draw a conclusion in a timely manner. The transient pattern database and the operating data are, therefore, converted into a smaller dimension using the principal component analysis (PCA). This paper describes the process of constructing the transient pattern database, dealing with principal components, and optimizing similarity measures.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
• /
• 2012.04a
• /
• pp.263-269
• /
• 2012

Condition-based maintenance (CBM) has been used as a useful concept for optimizing maintenance plan and decreasing maintenance cost in several kinds of plant sites. This study introduced an example that developed an integrated management system for maintenance parameters and hydraulic turbine of hydro-power plant in order to improve its maintenance system as applying CBM techinique. The integrated management system consists of three parts. One is a hardware part including PDA inspection system and several kind of precision measuring instruments. Another is a vibration monitoring system on hydraulic turbine. The other is a software part that takes charge of making hierarchy tree of maintenance parameters and their inspection route, managing accumulated database, assessing health condition of components, and supporting interface with other enterprise management system. The system has been installed at Chuncheon Hydro-power plant for test and demonstration. It is expected that the system can contribute database construction for diagnostics and prognostics on facility health condition and systematic accumulation of know-how on operation and maintenance of plant.

• Transactions of the Korean Society for Noise and Vibration Engineering
• /
• v.22 no.6
• /
• pp.574-581
• /
• 2012

Condition-based maintenance(CBM) has been used as a useful concept for optimizing maintenance plan and decreasing maintenance cost in several kinds of plant sites. This study introduced an example that developed an integrated management system for maintenance parameters and hydraulic turbine of hydro-power plant in order to improve its maintenance strategy as applying CBM techinique. The integrated management system consists of three parts. One is a hardware part including PDA inspection system and several kind of precision measuring instruments. Another is a vibration monitoring system on hydraulic turbine. The other is a software part that takes charge of making hierarchy tree of maintenance parameters and their inspection route, managing accumulated database, assessing health condition of components, and supporting interface with other enterprise management system. The system has been installed at Chuncheon hydro-power plant for test and demonstration. It is expected that the system can contribute database construction for diagnostics and prognostics on facility health condition and systematic accumulation of know-how on operation and maintenance of plant.

• Nuclear Engineering and Technology
• /
• v.30 no.4
• /
• pp.308-317
• /
• 1998

Ensuring occupational radiation exposure(ORE) as low as is reasonably achievable(ALARA) has been one of very important requirements in a nuclear power plant. It is well known that about 70 percent of occupational dose has incurred from maintenance jobs in the outage period. To reduce occupational dose effectively, the high-dose jobs in the outage period should be identified with their dose reduction potentials and methods. In this study, a PC-based ORE database program, INSTORE, is developed to evaluate ORE doses in individual jobs, and the ORE data of Kori Units 3 and 4 are assembled to the database. Based on customary job classification, radiation work is classified into 26 main jobs which comprise 61 detailed jobs, and occupational doses are assessed according to each detailed job. As a result, high-dose jobs are identified with dose reduction priority in terms of collective ORE dose. It is recommended that adeqaute dose reduction methods for these jobs should be prepared to improve their working conditions and procedures.

• International conference on construction engineering and project management
• /
• 2017.10a
• /
• pp.133-137
• /
• 2017

Nuclear power plants in Korea are usually built based on a duplicated model; so the project cost data of the preceding unit can be used as reference when estimating the project cost for the succeeding unit. However, since the contracting method is oriented towards the price, empirical factors such as making top-down estimations using the reverse calculation method based on the completion cost of the preceding unit is dominant. In order to develop a project cost database to resolve such problems, the detailed cost boundary of the project cost data must be categorized by project and by system. This study proposes a method to connect the code of account with the base quantities and the IAEA account, and proposes a database structure for the development of a project cost estimation system. The estimation system developed in the future is expected to utilize the proposed project cost data structure.

• KOREAN JOURNAL OF CROP SCIENCE
• /
• v.54 no.3
• /
• pp.332-338
• /
• 2009

Rapid extension of genomic database leads to the remarkable advance of functional genomics. This study proposes a novel methodology of functional analysis using 5-methyltrytophan (5 MT) mutant together with their 2-DE analysis and public microarray database. A total of 24 proteins was changed in 5 MT mutant and four remarkably different expressed proteins were identified. Among them, three spots were converted to Affymetrix probe. A total of 155 microarray samples from Gene Expression Omnibus (GEO) in NCBI was retrieved and followed by constructing gene co-expression networks over a broad range of biological issues through Self-Organising Tree Algorithm. Three co-expressing gene clusters were retrieved and each functional categorization with differential expression pattern was exhibited from 5 MT resistance mutant rice. It was indicated new co-expression networks in the mutant. This study suggests that on investigating possibility which correspond 2-DE to microarray database with their full potential.

• Nuclear Engineering and Technology
• /
• v.39 no.3
• /
• pp.215-220
• /
• 2007

The existing flooding Probabilistic Safety Analysis(PSA) was updated to reflect the Korean plant specific operating experience data into the flooding frequency to improve the PSA quality. Both the Nuclear Power Experience(NPE) database and the Korea Nuclear Pipe Failure Database(NuPIPE) databases were used in this study, and from these databases, only the Pressurized Water Reactor(PWR) data were used for the flooding frequencies of the flooding areas in the primary auxiliary building. With these databases and a Bayesian method, the flooding frequencies for the flooding areas were estimated. Subsequently, the Core Damage Frequency(CDF) for the flooding PSA of the Ulchin(UCN) unit 3 and 4 plants based on the Korean Standard Nuclear Power Plant(KSNP) internal full-power PSA model was recalculated. The evaluation results showed that sixteen flooding events are potentially significant according to the screening criterion, while there were two flooding events exceeding the screening criterion of the existing UCN 3 and 4 flooding PSA. The result was compared with two kinds of cases: (1) the flooding frequency and CDF from the method of the existing flooding PSA with the PWR and Boiled Water Reactor(BWR) data of the NPE database and the Maximum Likelihood Estimate(MLE) method and (2) the flooding frequency and CDF with the NPE database(PWR and BWR data), NuPIPE database, and a Bayesian method. From the comparison, a difference in CDF results was revealed more clearly between the CDF from this study and case (2) than between case (1) and case (2). That is, the number of flooding events exceeding the screen criterion further increased when only the PWR data were used for the primary auxiliary building than when the Korean specific data were used.

• Proceedings of the Plant Resources Society of Korea Conference
• /
• 2019.04a
• /
• pp.35-35
• /
• 2019

Aster spathulifolius Maxim. is belongs to the Asteraceae family which is distributed only in Korea and Japan. It is recognize as a traditionally medicinal plants and economically valuable in ornamental field. However, among the Asteraceae family, the Aster genus, which is lacks in genomic resources and information of molecular function. Therefore, we used high throughput RNA-sequencing transcriptome data of the A. spathulifolius to know molecular level function. DeNovo assembly produced 98,660 unigene with N50 value 1126 bp. Unigenes was performed to analyses the functional annotation against NCBI database like plant database of nucleotide (Nt) and non-redundant protein (Nr), Pfam, Uniprot, KEGG and Transcriptional factor (TF). In addition, Distribution of SSR markers also analyzed for future perfectives. Further, Comparing with other two Asteraceae family species like, Karelinia caspica and Chrysanthemum morifolium to the A. spathulifolius shows the number of gene that regulated in internal and external stress respectively salt-tolerant and heat and drought stress to understand the molecular basis related to the different environments stress.

• Proceedings of the Plant Resources Society of Korea Conference
• /
• 2018.04a
• /
• pp.5-5
• /
• 2018

Ginseng (Panax ginseng C.A. Meyer), one of the most widely used medicinal plants in traditional oriental medicine, is used for the treatment of various diseases. It has been classified according to its cultivation environment, such as field cultivated ginseng (FCG) and mountain cultivated ginseng (MCG). However, little is known about differences in gene expression in ginseng roots between field cultivated and mountain cultivated ginseng. In order to investigate the whole transcriptome landscape of ginseng, we employed High-Throughput sequencing technologies using the Illumina HiSeqTM2500 system, and generated a large amount of sequenced transcriptome from ginseng roots. Approximately 77 million and 87 million high-quality reads were produced in the FCG and MCG roots transcriptome analyses, respectively, and we obtained 256,032 assembled unigenes with an average length of 1,171 bp by de novo assembly methods. Functional annotations of the unigenes were performed using sequence similarity comparisons against the following databases: the non-redundant nucleotide database, the InterPro domains database, the Gene Ontology Consortium database, and the Kyoto Encyclopedia of Genes and Genomes pathway database. A total of 4,207 unigenes were assigned to specific metabolic pathways, and all of the known enzymes involved in starch and sucrose metabolism pathways were also identified in the KEGG library. This study indicated that alpha-glucan phosphorylase 1, putative pectinesterase/pectinesterase inhibitor 17, beta-amylase, and alpha-glucan phosphorylase isozyme H might be important factors involved in starch and sucrose metabolism between FCG and MCG in different environments.

• Proceedings of the Plant Resources Society of Korea Conference
• /
• 2020.12a
• /
• pp.14-14
• /
• 2020

In December 2019, the COVID-19 epidemic was discovered in Wuhan, China, and since has disseminated around the world impacting human health for millions. Herein, in-silico drug discovery approaches were utilized to identify potential candidates as Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) main protease (M^pro) inhibitors. We investigated several databases including natural and natural-like products (>100,000 molecules), DrugBank database (10,036 drugs), major metabolites isolated from daily used spices (32 molecules), and current clinical drug candidates for the treatment of COVID-19 (18 drugs). All tested compounds were prepared and screened using molecular docking techniques. Based on the calculated docking scores, the top ones from each project under investigation were selected and subjected to molecular dynamics (MD) simulations followed by molecular mechanics-generalized Born surface area (MM-GBSA) binding energy calculations. Combined long MD simulations and MM-GBSA calculations revealed the potent compounds with prospective binding affinities against M^pro. Structural and energetic analyses over the simulated time demonstrated the high stabilities of the selected compounds. Our results showed that 4-bis([1,3]dioxolo)pyran-5-carboxamide derivatives (natural and natural-like products database), DB02388 and Cobicistat (DB09065) (DrugBank database), salvianolic acid A (spices secondary metabolites) and TMC-310911 (clinical-trial drugs database) exhibited high binding affinities with SARS-CoV-2 M^pro. In conclusion, these compounds are up-and-coming anti-COVID-19 drug candidates that warrant further detailed in vitro and in vivo experimental estimations.