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Compilation of 104 Experimental Theses on the Antitumor and Immuno-activating therapies of Oriental Medicine (한의학의 항종양 면역치료에 관한 연구 -1990년 이후 발표된 실험논문을 중심으로-)

  • Kang Yeon Yee;Kim Tai Im;Park Jong Ho;Kim Sung Hoon;Park Jong Dai;Kim Dong Hee
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.17 no.1
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    • pp.1-24
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    • 2003
  • This study was done to compile 104 experimental theses which are related to the antitumor and immuno-activating therapies between February 1990 through February 2002. Master's and doctoral theses were dassified by schools, degrees, materials, effects, experimental methods of antitumor and immunoactivity, and results. The following results were obtained from this study : 1. Classifying the theses by the school, 34.6% were presented by Daejeon University, 29.8% by Kyung-hee University and 11.5% by Won-kwang University. Of all theses, 51.0% were aimed for the doctoral degree and 43.3% were for the master's degree. All of three universities have their own cancer centers. 2. Classifying the theses by herb materials, complex prescription accounted for 60.3%, single herb accounted for 24.8% and herbal acupuncture accounted for 14.2%. Considering the key principles of the traditional medicine, complex prescription was much more thoroughly studied than single herb prescription. The results showed that the complex prescription had both antitumor activity and immuno-activating activity, which might reflects on multi-activation mechanisms by complex components. 3. Classifying the theses by the efficacy of herbs examined, in single herb, invigorating spleen and supplementing was 35.5%, expelling toxin and cooling was 29.0%, activating blood flow and removing blood stasis was 12.9%. In herbal acupuncture, invigorating spleen and supplementing was 52.9%, expelling toxin and cooling was 29.4%. In complex prescription, pathogen-free status was 41.9%, strengthening healthy qi to eliminate pathogen was 35.5%, strengthening healthy qi was 22.6%. It is presumed that the antitumor and immunoactivating therapy based on syndrome differentiation is the best way to develop oriental oncology. 4. Classifying the theses by antitumor experiments, cytotoxic effect was 48.1 %, survival time was 48.1 % and change of tumor size was 42.3%. Survival rate was not necessarily correlated with cytotoxicity. These data reflect the characteristic, wholistic nature of the oriental medicine which is based on BRM (biological response modifier). 5. Classifying the theses by immunoactivating experiments, hemolysin titer was 51.0%, hemagglutinin titer was 46.2% and NK cell's activity was 44.2%. In the future studies, an effort to elucidate specific molecular and cellular mechanisms of cytokine production in the body would be crucial. 6. Classifying the theses according to the data in terms of antitumor activity, 50% was evaluated good, 24.0% was excellent, and 15.5% have no effect. In an evaluation of immuno-activating activity, 35.9% was excellent and 18.0% showed a little effect. The index point, as described here, may helps to use experimental data for clinical trials. Changes in index points by varying dosage implicate the importance of oriental medical theory for prescription. 7. In 167 materials, IIP (immunoactivating index point, mean : 3.12±0.07) was significantly higher than AIP(antitumor index point, mean : 2.83±0.07). These data demonstrate that the effect of herb medicine on tumor activity depends more on immunoactivating activity than antitumor activity. This further implies that the development of herbal antitumor drugs must be preceded by the mechanistic understanding of immunoactivating effect. 8. After medline-searching tumor and herb-related articles from NCBI web site, we conclude that most of the studies are primarily focused on biomolecular mechanisms and/or pathways. Henceforth, we need to define the biomolecular mechanisms and/or pathways affected by herbs or complicated prescriptions. 9. Therefore, the most important point of oriental medical oncology is to conned between experimental results and clinical trials. For the public application of herbal therapy to cancer, it is critical to present the data to mass media. 10. To develop the relationship of experimental results and clinical trials, university's cancer clinic must have a long-range plan related to the university laboratories and, at the same time, a regular consortium for this relationship is imperative. 11. After all these efforts, a new type herbal medicine for cancer therapy which is to take care of the long-term administering and safety problem must be developed. Then, it would be expected that anti-tumor herbal acupuncture can improve clinical symptoms and quality of life (QOL) for cancer patients. 12. Finally, oriental medical cancer center must be constructed in NCC (National Cancer Center) or government agency for the development of oriental medical oncology which has international competitive power.

Status of oral health care provided by care workers in accordance with their oral health awareness and knowledge (요양보호사의 구강보건인식 및 지식에 따른 구강보건제공현황)

  • Kim, Min-young;Kang, Kyung-hee
    • Journal of the Korea Convergence Society
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    • v.7 no.6
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    • pp.161-166
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    • 2016
  • By studying the status of oral health provided by caregivers working in care facilities in accordance with their oral health awareness and knowledge, this thesis sought to find a plan of development to enhance the oral health for the elderly in care facilities. A survey was carried out from the 16th of August to the 2nd of September 2016, with 200 care givers as the subjects, working in 14 long-term care facilities for elderly, located in the city of D. Frequency analysis and independent sample t-test were conducted of the collected data, using SPSS 18.0. The results of the study were as follows; for gender, female was 91.5% which was higher than that of male, and married for marital status, 50 for age, highschool for education, christian for religion were shown to be the highest. The highest number of people for daily care was 6~7. In terms of status for providing oral health and oral health awareness of caregivers, the existence of oral hygiene guideline was statistically meaningful, and in terms of the status of oral health provided and oral health knowledge, there were notable differences in storage of dentures, and usage of mouthwash(p<.05).

The Effects of Medical Service Qualities on Satisfaction, Relationship Quality, and Revisit Intent in Long Term Care Hospital an Elderly Out-patients (요양병원을 이용하는 노인에게 의료서비스품질이 환자만족, 관계품질 및 웹사이트 재이용의도에 미치는 영향)

  • Kim, Byung-Yong;Jeong, Myeong-Ae
    • Health Policy and Management
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    • v.22 no.2
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    • pp.183-206
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    • 2012
  • Changing social conditions have resulted in a situation where elderly patients are no longer cared for by family and where medical care hospitals play a more prominent role. In this study, the unique elements of the medical service required from a long term care hospital were identified using conventional and exploratory analysis, and the causal relationship between medical service quality, relationship quality, and Revist intent was confirmed. The intermediary role and the quantitative importance of relationship quality (including trust and commitment) were also characterized. This study identifies the key points and indicators that the administrators of a long term care hospital can use to effectively plan their medical service offering in order to secure the commitment of customers through relationship quality. The theoretical indications of this study are set out below. First, four factors are selected as being the key elements determining service quality: medics, administrative service, healthcare environment, and subsidiary facilities. Second, it seems that medics, administration service, and the healthcare environment have some effect on the evaluations made in relation to trust and satisfaction (subsidiary facilities are not considered to be a key element). Third, patient satisfaction has a positive impact on trust and commitment and can be regarded as a key element for establishing connections. Fourth, commitment is likely to be strengthened when trust is significant. Fifth, as trust and commitment increase, revist intent strengthens. Lastly, this study illustrates how the levels of trust and commitment play a modulating role between patient satisfaction and revist intention. There are many practical indications from the findings of this study. First, the influences of medics, the administrative service, and the healthcare environment on trust and satisfaction vary. Especially, the healthcare environment is likely to be more important than medics. Accordingly, it is essential to establish an elderly-friendly environment, to improve a hospital's structure, and to maintain a clean environment. Second, medics must show compassion to their patients and be patient when providing explanations to elderly patients who often lack powers of concentration. Third, in order to establish patient trust, it is essential that medics provide an excellent medical service. Ultimately, these elements of relationship quality may strengthen the revist intention of elderly patients.

A Study on the Storytelling and its Application : Focusing on the Panmunjom and the surrounding DMZ (판문점 및 주변 DMZ 지역의 스토리텔링과 활용방안에 관한 연구)

  • Lee, Dongmi
    • 지역과문화
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    • v.6 no.4
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    • pp.23-45
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    • 2019
  • The main research is on how to find source stories and develop and utilize content that will properly show the value of Panmunjom and the surrounding DMZ on the Korean Peninsula, which are receiving worldwide attention. Three methods were used as research for the high-end branding of Panmunjom and the surrounding DMZ. The first is the interest of prospective visitors through the travel cycle, using Joseph Campbell's "The Hero's Journey." The second was to incorporate Roland Bart's "third meaning" into the subjective travel and emotional stimulation, which is the trend of modern travel. The third introduced Kevin Lynch's theory and tried to place five elements of the path, edge, district, node and landmark in the core location of Panmunjom. Through the study, the excavation of contents in Panmunjom and the surrounding DMZ needs to be collected to a third meaning using a direct interview method that listens to the stories of related figures as well as organizing historical events. The priority should be given to those over the age of 80 and interviews should be conducted at least three times and over three generations. The process of building it into an archive, selecting a story, and then going through a culture collage and networking and branding takes place in five stages. This can create a virtuous circle of content processing, content utilization, job creation in the region and revitalizing the local economy through discovery of source stories and storytelling. Content development should be able to touch sensibility while saving time, history, place, originality and sincerity. Taking the center between tourism and travel, development and damage concerns, a careful but long-term plan and large-scale discovery of source stories should be made, and a consensus should be formed on the need for proper storytelling.

UI Design Survey of Mobile App for the Activation of Traditional Market (전통시장 활성화를 위한 모바일 앱의 UI 디자인 조사)

  • Lee, Joo-Hee
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.15 no.1
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    • pp.277-282
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    • 2015
  • According to International Data Corporation(IDC) showed that PC sales for the first time ahead of the global smart phone sales in the fourth quarter of 2010. This opportunity as a smart phone application and mobile web-sites has been launched to accelerate the development of mobile services in a variety of fields. In addition to the support plan for the activation of the local traditional market from the second half of 2012 to make it easier to find information on the traditional markets of the country expanded and reorganized the traditional market-related web-site, trying to catch the foot of the youth in the online. This study is to increase the number of tourists visiting the traditional market or local residents and young people and to provide a basis for the development of mobile UI design for mobile application to investigate the local traditional market apps that are currently available.

A Study on the Characteristics of Organic Design of Alvar Aalto (알바 알토(Alvar Aalto)의 유기적 디자인 특성에 관한 연구)

  • 이종선
    • Korean Institute of Interior Design Journal
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    • no.12
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    • pp.91-99
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    • 1997
  • Alvar Aalto has pursued National Romanticism, cultural art movement in scandinavian peninsula, organic concepts of growth and suitability, comprehensive view of nature including a possibility of coexistance of human-being and the nature well harmonized. For instance, his design expressed local features of the nature, human emotions instead of geometical arts and mathematical principles. It is noteworthy today that he built up the identity with satrical architecture vocabularies, different from modern arch-itechtural idiology. The characte-ristics of his design related to interior architecture are collectively as follows; The first, Space discontinuity of the interior and exterior, gradual process by joints which are inclined to collage with many shapes in plan and section of the space and such joints are adjusted by sensual ways and stressed with inner collectivity in his works. The second, He pursued the architectural orderfor modern irreqularity, various changes and sensual harmonies. As result, free curved line, fan shape and irregular modeling were individually expressed by technics of natural features and national characteristics of Finland. The third, Organic synthesis. A harmony through med-ums in its space, materials and space effectiveness relations are made and expressed for mixed design especially harmonized of all the materials he planned, entire harmony with total design, itemized details, materials and furnitures in entire space. The fourth, The interest of the nature based on his sense harmonized with nature made him mainly use native materials, lumbers and red bricks masonry and showed and arranged various interior sky light and grazed in to let natural light in, harmony with garden to sensually cohere to the nature and courtyard, etcetera. His major subject are to direct architectural developments through the nature and human-being in his works. At this point, it is considered that his direction of the locality and independence as a human-being made the concepts of organic space structure possible.

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A Model of System Reformation for Specialization in Home Economics of Vocational High School in JellaNamdo (가사ㆍ실업계열 특성화 고등학교의 체제 개편 모델 - 전라남도를 중심으로 -)

  • 유명의;서리나
    • Journal of Korean Home Economics Education Association
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    • v.14 no.3
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    • pp.11-24
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    • 2002
  • This study was to propose a basic model of specialization in home economics for vocational high school development in JellaNamdo. The results were summarized as follows. First. based on the changes in economic environment into service industry and national educational policy and local vocational educational Policy, it may be good time to socially discuss special vocational high school in home economics in JellaNamdo in the light of meeting local students' demand. Secondly, considering local students' preference and the conditions of local economy and industry. Thirdly, the system for specialization in home economics of vacational high school may be suggested. The basic model was organized plans of system reformation by stages, a substantial plans, and academic or employment course development. System reformation plans was that the high school-concentrated district should be first selected by area and department and one high school should be selected as special high school in home economics. Then specific method should proceed school name, the measure to recruit students, specific method for reorganizing department. and curriculum. Finally, the annual plan to establish new department and to recruit students should be Prepared. Substantial plans were to actually forward such methods to reorganize system and to enhance the qualify of vocational high school education. the method for making substantial should be studied further It may include: the methods to ensure special teachers, training room, and facilities. the prospect and direction of career development, employment, or initiation, special research, and the application to educational environment. Employment courses were developed SOHO establishment in small capital and special store management. And academic courses was to enter a collage or university in conjunction with major departments.

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The Relationship of Fatigue, Self Efficacy, Family Support and Sleep Factor in Hemodialysis Patients (혈액투석환자의 피로와 자기효능감, 가족지지 및 수면요인과의 관계)

  • Choi, Eun Young;Lee, Hyang Yeon
    • Korean Journal of Adult Nursing
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    • v.17 no.3
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    • pp.435-443
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    • 2005
  • Purpose: This study investigated the degree of fatigue of hemodialysis patients, and finds the relationship between fatigue and self-efficacy, family support, and sleep factor. Also, this study was purposed to provide fundamental data to help set up a nursing plan and intervention for recovery and mitigation of hemodialysis patient's fatigue. Method: The subjects in this study were patients treated as hemodialysis patients in Kwangjoo City. Data, subjects are 143 patients. Fatigue was measured using Lee's scale(1991), Self-efficacy using Kim's scale(1995), and Family support using Kim's scale(1993). For the analysis of collected data, Cronbach alpha, descriptive statistics, t-test, ANOVA, Pearson's correlation coefficient, Stepwise multiple regression were used for statistical analysis by SPSSwin(version 11.0) program. Result: Fatigue degree of hemodialysis patients averaged 4.22. Among 143 hemodialysis patients, 70.63% patients answered that they had felt fatigue as noted in this study. The weariest time was after hemodialysis for 21.0% patients. There was significant difference according to the diagnosis period. The patients who were diagnosed over one year had felt more fatigue than ones who were diagnosed within one year. Fatigue was significantly associated with self-efficacy, family support, and sleep factor. Self-efficacy could explain 14.6% of fatigue. Conclusion: The fatigue degree relates with all, self-efficacy, family support, and sleep factor. Especially, it is affected by self-efficacy among them. Thus, the program should be developed to mitigate fatigue as the self-efficacy of hemodialysis is enhanced.

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A Study on the International Competitiveness of the Korea Liner Shipping Commany (우리나라 정기선사의 국제경쟁력에 관한 연구)

  • Lee, Jae-Kyu
    • Korean Business Review
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    • v.11
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    • pp.365-384
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    • 1998
  • Under the rapid change of the world shipping industry, the liner shipping company in Korea should initiate the adaptation power, counterplot for survival, and continuous development. The world shipping industry is in the middle of the wave for the liberalization and openness of it. According to this change in world shipping industry, it is the fact that government policy for shipping industry should start turning its direction from the protectionism to the liberalism. Under this kinds of situations, this study firstly treated the liner shipping company and its governmental policy of Korea and Japan. Based on those studies, analysis of the liner shipping company operation and management reality was executed. Through the execution of studies, the problems which should be solved for development occurred. Furthermore, this thesis takes two way of researches of literature and actual proof for reinforcement plan of international competitiveness. This standard time period of study is set in 1993 except the irregular liner shipping company.

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A Study of The Nursing Education Concerning Two Years Associate Degree Nursing Program (간호 교육에 대한 일 연구 -2년제 초급대학 과정 중심으로-)

  • 변창자
    • Journal of Korean Academy of Nursing
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    • v.4 no.3
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    • pp.63-79
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    • 1974
  • 1. The purpose of this study. The purpose of this study is to plan and investigate short-term nursing education of two-years associate degree program to produce middle-level professional nurses which are needed by-society and nation. Current nursing education in Korea is divided into four years degree program, three years diploma program Even (though) there are differences in the aims of their education, the curriculums are not much different between the education for producing leaders which is its basic purpose and training middle-level professional nurses. Therefore the purpose of associate degree program lies in minimizing the waste of time and finance which are invested for long-term education for middle-level professional nurses. And also this coincide with the policy of national technical training and definite supply of nurse manpower according to health policy for effective role and ability of nurse. 2. The method of study. This is based on the study of literature, research on the actual condition and investigation of opinion- through questionnaire. L) The study of literature: Domestic and foreign literatures for two years associate degree program were studied and investigated. 2) Research on the actual condition : Current three years nursing education program was collected and analysed. 3) Investigation of opinion. The problem of curried nursing education system and the possibility of two years associate degree program were investigated through questionnaire. 3. The result of the study. 1) The trend of recent nursing education. a. The aims of nursing in past chiefly taking care of physical disease of patient has recently changed to nursing of character including physical, mental, socio-economic, educational and psychological condition. b. For the performing systematic and effective nurse's duty according to her role, the-change of educational system which is classified as a range of education the period of education and certificate after graduation has been enforced or fulfilled. c. Nursing education also has a trend to become a collage or two years associate degree program which can get same legal protection as other educational institutions whose basic purpose is education. Attached nursing school to hospital is getting disappeared because of disadvantage of educational system. 2) Problems. Depending upon research on actual condition of current 3 years nursing education program. a. There are too many subjects. b. Contents of education could be doubled because major subjects are subdivided in detail. c. The credits for graduation are too heavy comparing to the period of study or the ability of students. (The necessary credits are 150.8 for three years according to actual investigation 4. There is no certain standard in organizing curriculum therefore there are too much differences between schools. 4. Basic Plan. The plan for two years associate degree program in nursing education depending on demand of professional nursing field of society is based on following items. 1) Training middle-level professional nurse lay emphasis on liberal arts and basic major field. 2) Liberal arts are divided into required and optional subjects and students could take courses by choice. 3) Major subjects are compound together by fields and they become the sciences of nursing Ⅰ,Ⅱ,Ⅲ,Ⅳ and every items has its educational purposes and contents major study includes laboratory practice and clinical experience. 4) The required credits for graduation are to which means 17-18 credits a semester. The above has been planned to solve the problems of current three years nursing education program. In conclusion for the achievement of this system, following items are needed. 1) It is necessary to change educational administration and system such as amendment of educational law or order of educational application of law. 2) Qualified professors should be available to understand and develope the idea or purpose of this educational system. 3) Local medical institutions should be opened widely and educational for clinical training. 4) The job after graduation should he secured positively.

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