• Journal of Welding and Joining
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• 제5권4호
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• pp.47-53
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• 1987

The purpose of this study is to reexamine our test method in the light ofstatistical methods for data interpretation. Our trial to apply Plackett-Burman statistical model in multifactorial welding experiments shows that is saves much time and cost and extracts very accurate results. In this study, the parametric effects of bead shape on pulse MIG process in Cu-Ni alloy are investigated for verifying our trial.

• Korean Chemical Engineering Research
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• 제54권6호
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• pp.812-816
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• 2016

We isolated a novel methylotrophic bacterium from soil collected in Dongducheon Environment Affairs Agency. The isolate was identified as Methylobacterium sp. WJ4 based on phylogenetic analysis. Plackett-Burman design was employed for screening eight parameters of nitrate mineral salts (NMS) medium for cell growth of a newly isolated Methylobacterium sp. WJ4 with experimental validation. Trace element solution and vitamin stock were found to affect cell growth, which can be further optimized for increased cell growth. This is the first report of screening parameters of NMS medium which affect cell growth of strain belonging to the genus Methylobacterium using Plackett-Burman design.

• Journal of Microbiology and Biotechnology
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• 제12권3호
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• pp.355-359
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• 2002

The Plackett-Burman experimental design was employed to evaluate the relative importance of medium constituents of each medium for enhanced griseofulvin production by Penicillium griseofulvum MTCC 1898 and Penicillium griseofulvum MTCC 2004. It was found that the medium constituents, sucrose, $K_2HPO_4,\;NaNO_3,\;and\;FeSO_4{\cdot}7H_2O$, significantly influenced the griseofulvin production by Penicillium griseofulvum MTCC 1898. In the case of Penicillium griseofulvum MTCC 2004, lactose, glucose, and $MnSO_4{\cdot}H_2O$ significantly influenced the griseofulvin production.

• 대한안전경영과학회지
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• 제7권5호
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• pp.69-84
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• 2005

This paper proposes statistically designed experiments which provide a proactive means to implement safety and environmental applications. Minimal experimental designs such as fractional factorial design, Plackett-Burman design, Box-Behnken design are economical and can be achieved tremendous savings with relatively few experiments. These experimental designs and analysis methods are illustrated with cases.

• Journal of Microbiology and Biotechnology
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• 제15권5호
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• pp.930-937
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• 2005

The Plackett-Burman design and the response surface method (RSM) with a central composite design (CCD) were employed to develop a culture medium for ansamitocin P-3 production using Actinosynnema pretiosum ATCC 31565. Among the 11 nutrients tested using the Plackett-Burman design, two carbon sources, sucrose and dextrin, and two nitrogen sources, polypeptone and yeast extract, were selected. Optimization of the concentrations of the selected nutrients was then performed using RSM with CCD. After two rounds of RSM, the optimum concentrations ($\%w/v$) of sucrose, dextrin, polypeptone, and yeast extract were identified as 4.5, 4.5, 0.16, and 0.89, respectively. The maximum ansamitocin P-3 titer was 45.2 mg/l with the optimized medium, which was about 6 times higher than that (7.315 mg/l) obtained with an $R_{2}YE$ medium before optimization.

• Korean Chemical Engineering Research
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• 제53권3호
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• pp.321-326
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• 2015

Plackett-Burman (PB) and Box-Behnken (BB) experimental designs were used to optimize fermentation variables for the biotransformation of glycyrrhizin (GL) to monoglucuronyl-glycyrrhetinic acid (MGGA). The PB design was first used to screen the important factors among the medium variables. The steepest ascent method was used to approach the optimum range for each of these factors. The BB design was finally used to analyze the response surfaces of the screened factors for further optimization. The optimized conditions for this system were 0.7 g/L $MgSO_4{\cdot}7H_2O$, 1.19 g/L GL, and cultivation for six days. The biotransformation of GL to MGGA could reach up to 35.72%, which is a good result for this kind of transformation.

• Journal of Microbiology and Biotechnology
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• 제22권12호
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• pp.1767-1775
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• 2012

The Cr(VI) removal capability of Acinetobacter junii VITSUKMW2 isolated from the Sukinda chromite mine site was evaluated and enhanced using statistical design techniques. The removal capacity was evaluated at different pH values (5-11) and temperatures ($30-40^{\circ}C$) and with various carbon and nitrogen sources. Plackett-Burman design was used to select the operational parameters for bioremediation of Cr(VI). Three parameters (molasses, yeast extract, and Cr(VI) concentration) were chosen for further optimization using central composite design. The optimal combination of parameters was found to be 14.85 g/l molasses, 4.72 g/l yeast extract, and 54 mg/l initial Cr(VI), with 99.95% removal of Cr(VI) in 12 h. A. junii VITSUKMW2 was shown to have significant potential for removal of Cr(VI).

• Communications for Statistical Applications and Methods
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• 제6권3호
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• pp.707-718
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• 1999

Non-regular designs such as the Plackett-Burman(PB) design have traditionally been used for screening only main effects because of complex aliasing. But it was found that these designs could be used to estimate the 2-factor interactions as well as main effects through the hidden projection property. The goal of this paper is to propose the estimable model when projecting the 12-run PB design using the algebraic geometric method. The core of this method considers the design as a affine variety and the Grbner basis of the design ideal for this affine variety gives the estimable polynomial models. As the results of applying the 12-run PB design it is actually found that this design has the models not only with 2-factor interactions but with 3-factor. This design is the maximal fan in 4-factor projection.

• Journal of Microbiology and Biotechnology
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• 제8권4호
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• pp.341-346
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• 1998

Optimization for the production of Pest an was followed by the Plackett-Burman Design, using modified Czapek-dox medium as the starting point. At the flask level, $K_2HPO_4$, $MgSO_4{\cdot}7H_2O$, and aeration variables positively affected the Pestan production, DCW (dry cell weight), apparent viscosity, and flocculating activity response. KCI and $FeSO_4{\cdot}7H_2O$ negatively affected the Pestan production, DCW, apparent viscosity, and flocculating activity response. Aeration variable was shown to have a positive effect on only the flocculating activity response among Pestan production, DCW, and apparent viscosity responses. In comparison of the positive and negative variables media conditions, Pestan production and flocculating activity differed by about 9 and 125 times, respectively. In particular, at the jar fermentor level, the aeration variable was the most important factor of the all responses (pestan production, DCW, apparent viscosity, flocculating activity, and anionic charge density). The flocculating activity and apparent viscosity of Pestan were closely related to the molecular chain length and charge density.

• 한국정보과학회논문지:시스템및이론
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• 제37권3호
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• pp.127-137
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• 2010

다양한 과학 분야에서 대규모의 계산집중적인 어플리케이션들이 많은 그리드 자원을 활용해감에 따라 그 실행 관리와 제어의 어려움도 증가하였다. 어플리케이션의 반복되는 실행으로 축적된 작업 이력을 참조하여 어플리케이션의 특성을 파악하고 그리드 자원 선택 정책을 결정하였다. 본 논문은 그리드 컴퓨팅 환경과 이를 활용한 어플리케이션의 이력을 분석하기 위해 통계적 기법인 PBDF(Plackett-Burman with Fold-Over)계획법을 적용하였다. PBDF는 그리드 환경과 어플리케이션에서 주요한 요인들을 파악하고, 그것들이 얼마만큼 영향을 미치는 가를 수치화한다. 영향력 큰 요인은 작업 이력에서 참조 프로파일을 찾고 적절한 자원을 선택하는데 사용하였다. 응용의 수행 결과를 다시 작업 이력에 포함시키고 인자의 신뢰도를 조정하였다. 본 연구는 항공우주 연구 그리드의 작업 이력을 분석하여 적응형 자원 선택 알고리즘을 제안하였다. 주요한 요인들의 영향력을 계산하고 자원 선택 정책에 반영하는 실험을 하였다. 또한, 수행이 끝난 후 인자의 신뢰도를 평가해 그리드 환경 변화에 적응하는 알고리즘의 유효성을 검증하였다. 오류가 빈번한 그리드 환경에서 자원 선택 기법을 평가하기 위해 다양한 시나리오에서 그 적응력을 실험하였다.