• Asian-Australasian Journal of Animal Sciences
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• 제27권11호
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• pp.1577-1583
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• 2014

Encapsulation is a method used to protect material from certain undesirable environments, for controlled release at a more favorable time and place. Animal productivity would be enhanced if feed additives are delivered to be utilized at their site of action, bypassing the rumen where they are likely to be degraded by microbial action. A novel method of encapsulation with sesame gum was used to coat nitrate, a known enteric methane mitigating agent, and tested for the effect on methane reduction and other in vitro fermentation parameters using rumen fluid from cannulated Hanwoo steers. Orchard grass was used as basal diet for fermentation. The treatments were matrix (1.1 g sesame gum+0.4 g sesame oil cake) only, encapsulated nitrate (matrix+nitrate [21 mM]), free nitrate (21 mM), and a control that contained no additive. Analyses of fermentation parameters were done at 0, 3, 6, 9, 12, 24, and 48 h time periods. In comparison to control, both free and encapsulated nitrate produced significantly reduced (p<0.01) methane (76% less) and also the total volatile fatty acids were reduced. A significantly higher (p<0.01) concentration of ammonia nitrogen was obtained with the encapsulated nitrate treatment (44%) compared to the free form (28%) and matrix only (20%) (p = 0.014). This might suggest slow release of encapsulated nitrate so that it is fully reduced to ammonia. Thus, this pioneering study found a significant reduction in methane production following the use of sesame gum encapsulated nitrate that shows the potential of a controlled release system in enhancing sustainability of ruminant production while reducing/eliminating the risk of nitrite toxicity.

• Asian Pacific Journal of Cancer Prevention
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• 제13권11호
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• pp.5605-5611
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• 2012

Background: In the last two decades, pioneering research on anti-tumour activity of saffron has shed light on the role of crocetin, picrocrocin and safranal, as broad spectrum anti-neoplastic agents. However, the exact mechanisms have yet to be elucidated. Identification and characterization of the targets of bioactive constituents will play an imperative role in demystifying the complex anti-neoplastic machinery. Methods: In the quest of potential target identification, a dual virtual screening approach utilizing two inverse screening systems, one predicated on idTarget and the other on PharmMapper was here employed. A set of target proteins associated with multiple forms of cancer and ranked by Fit Score and Binding energy were obtained from the two independent inverse screening platforms. The validity of the results was checked by meticulously analyzing the post-docking binding pose of the picrocrocin with Hsp90 alpha in AutoDock. Results: The docking pose reveals that electrostatic and hydrogen bonds play the key role in inter-molecular interactions in ligand binding. Picrocrocin binds to the Hsp90 alpha with a definite orientation appropriate for nucleophilic attacks by several electrical residues inside the Hsp90-alpha ATPase catalytic site. Conclusion: This study reveals functional information about the anti-tumor mechanism of saffron bioactive constituents. Also, a tractable set of anti-neoplastic targets for saffron has been generated in this study which can be further authenticated by in vivo and in vitro experiments.

• 디자인학연구
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• 제12권3호
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• pp.43-52
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• 1999

바우하우스에 있어서 타이포그래피의 다양한 실험은 인쇄공방을 중심으로 전개되었으며 바이마르 후기에 이르러서 이 공방의 책임자가 된 모홀리-나기는 기능주의적 사고방식으로부터 접근하여 먼저 활자의 개량을 요구하고 이를 바탕으로 비우하우스 통일문자의 제작과 아울러 사진기술을 이용한 영상과 문자를 결합시켜 새로운 형태의 타이포그래피인 다이포 포토를 개발하였다. 또한 모홀리-나기의 이념을 이어받아 합목적적인 조형을 목표로 한 헤르베르트 바이어는 심리학 생리학의 제반법칙에 기초를 둔 다양한 광고제작물을 실현하여 현대 정보광고의 토대를 마련했으며, 바이어의 뒤를 계승한 요스트 슈미트는 기능성에 입각한 레터링, 타이포그래피 교육과 실천에 주력하는 한편 전시 계획에 따른 타이포그래피의 효율적 공간구성으로 디스플레이 디자인 영역을 새롭게 개척했다. 이와 같이 바우하우스 작가들에 의해 시도된 일련의 타이포그래피 실험은 동일한 시대, 같은 지도자에 의해 계승되었슴에도 불구하고 전통과 인습에 얽매이지 않는 창조정신과 다가오는 시대를 예견하는 뛰어난 통찰력, 역동적인 대응방식을 통하여 현대 시각커뮤니케이션의 나아갈 방향을 제시해 주고 있다.

• 한국해양공학회지
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• 제25권2호
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• pp.134-144
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• 2011

In this paper, the global study trends for material behaviors are investigated regarding the static and dynamic hardenings and final fractures of marine structural steels. In particular, after reviewing all of the papers published at the 4th and 5th ICCGS (International Conference on Collision and Grounding of Ship), the used hardening and fracture properties are summarized, explicitly presenting the material properties. Although some studies have attempted to employ new plasticity and fracture models, it is obvious that most still employed an ideal hardening rule such as perfect plastic or linear hardening and a simple shear fracture criterion with an assumed value of failure strain. HSE (2001) presented pioneering study results regarding the temperature dependency of material strain hardening at various levels of temperature, but did not show strain rate hardening at intermediate or high strain rate ranges. Nemat-Nasser and Guo (2003) carried out fully coupled tests for DH-36 steel: strain hardening, strain rate hardening, and temperature hardening and softening at multiple steps of strain rates and temperatures. The main goal of this paper is to provide the theoretical background for strain and strain rate hardening. In addition, it presents the procedure and methodology needed to derive the material constants for the static hardening constitutive equations of Ludwik, Hollomon, Swift, and Ramberg-Osgood and for the dynamic hardening constitutive equations of power from Cowper-Symonds and Johnson-Cook.

• 복식
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• 제61권1호
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• pp.69-83
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• 2011

This study applied cartoon-like simple and implicit symbol of Keith Haring works to tubular jacquard knit, designed woman casual knit wear with fun, explicit and activities using fluorescent yarns with explicit features. This study aimed to propose the directions for new market pioneering that meets the emotional requirements of modern people by raising the level of utilization and expression area of knit fashion, and to present the constructive directions for high value-added knit wear by designing highly effective knit wear. Methods of this study examined the lifetime and artistic background of Keith Haring and collected his works through searching of internet, scholastic publications or thesis. Formative types and colors of works collected were analyzed and classified according to characteristic standards of Haring and characteristic formativeness and color of works were extracted. The result of this study is as shown below: First, the feature of his works can be summarized into motif that has symbolic and implicit cartoon-like lines including narratives as well as enormous number of works. Such feature is very suitable for variation and recombination in realization of design and has unlimited potentials for development. Second, image colors can be extracted such as black and white, original color and fluorescent paints, which reflects the intention of artist who put focus on communication with the public. Such color feature is very suitable for design motif that has explicitness of reflecting the intention of artist through use of special fluorescent yarn. Third, I made it as reversible wear that has effects of increasing or decreasing the explicitness according to color area ratio using the feature of textures allowing use of both sides as well as form stability of tubular jacquard. Fourth, by adjusting the thickness of fabric with controlling of ply in fabric using poly yarn and wool union yarn, I could obtain good results of study in terms of technique that can express various materials with embossed dynamic effects of unevenness on flat surface.

• 대한후두음성언어의학회지
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• 제12권2호
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• pp.152-157
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• 2001

Background : Electrolarynx, Esophageal voice, and Silicone voice prosthesis with tracheoesophageal(T-E) fistula have been used as vocal rehabilitating methods for the post-laryngectomized patients. Prosthetic rehabilitation of voice after total laryngectomy has gained wide acceptance and has become a common practice in many clinics since the pioneering works of Singer and Blom In 1979. Since the introduction of tracheo-esophageal puncture and application of Blom Singer$\circledR$ voice prosthesis in 1980, several reliable voice prostheses have been developed and are successfully being used. Objectives : Even though quality of voice produced by Silicone voice prosthesis with T-E fistula is superior to other modalities, it still has some disadvantages. We devised a new cannulatyped silicone voice prosthesis. Methods : 1) Devising a new prototype of cannula-typed silicone voice prosthesis. 2) Application of the prototype using canine animal model(laryngectormized dog) and fitting trial on human patient whose previously inserted Silicone voice prosthesis is not functioning due to presumed fungal infection. Discussion : Final form of prototype was made after several times of major and minor modifications. Insertion of the newly developed Cannula-typed Silicone voice prosthesis on canine animal model and human trial were done without any difficulty. There were no serious leakage of saliva or food during swallowing. Conclusion : The newly developed Cannula-typed Silicone voice prosthesis(So-Mang$\circledR$) and the modified replacement method will further improve the results of post-laryngectomized prosthetic voice rehabilitation. Long-term animal study and human trial are planned in the near future.

• 한국수학사학회지
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• 제23권2호
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• pp.1-21
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• 2010

광무 9년(1905년) 12월5일 한국인 최초의 이학사인 유일선이 발행한 우리나라 첫 번째 수학 저널인 <수리학잡지 (數理學雜誌)> 가 사료로 최근 수학계에 그 존재를 알렸다. 이 저널은 매월 5일 발행한 정기간행물로 2년 정도 (광무10년 6월5일 제 7호까지) 발간된 후 폐간되었다. 발행은 유일선에 의해 1907년 설립된 정리사(精理舍) 가 위치한 서울 남대문 근처 상동 (尙洞) 의 '수리학잡지사' 를 통하여 이루어졌다. 그 내용은 근대수학의 기초 내용을 강론형식으로 서술한 '산술신강의' 와 '산술문제 해설' 및 '이과 (理科)' 로 구성되었다. 본 논문은 유일선이 발행한 한국 최초의 수학 저널 <수리학잡지> 의 창간호의 내용을 분석하고 그 내용을 구체적으로 소개하는데 그 목적이 있다.

• 한국실내디자인학회논문집
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• 제27권1호
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• pp.109-116
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• 2018

Prairie style houses in first stages of Frank Lloyd Wright's architecture activity pay a leading role in the process of house modernization as reflecting social and economic circumstances of the time based on traditional house style of the States. Wright's first work after retiring from L. Sullivan's office, Winslow house in 1983 is pioneering work predicting prairie house. This is because this house has only one modern architecture language of Wright and follow no style prevailing of the time. So, a researcher analyse Winslow house within the framework of functional thinking and new formative value creation in the modernization process of western house. Through this, The goal of this study is to find out modern characteristics and the meaning of Winslow house in modernization process prior to the 1900s. Firstly, the followings are modern characteristics of Winslow house. First, Winslow house has original planning breaking from custom based on modern functional and reasonable thoughts, and has practical space reflecting resident's inner demand. Second, Winslow house has modern new plastic value through original exterior breaking from custom and integrated shape of inner-outer space and structure. Secondly, the followings are the meaning of Winslow house in modernization process prior to the 1900s. First, Wright intend to suggest directions of residence modernization through Winslow house before designing Prairie style houses in earnest. Second, mixing of modern vocabulary and eclecticism show a sign of residence modernization process on the time. Third, inner-outer flowing space, opening space concept of Winslow house has innovative meanings predicting spacial characteristics of modern architecture.

• 패션비즈니스
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• 제11권5호
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• pp.90-99
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• 2007

Arts is the expression of reasoning and conscious life of human and arouse human the concept of existence, utmost emotion and excellent thoughts. Also it makes humans life very abundant. I make it come first to get rid of the art thirst on the opposite sight of technical one for hair as on part of humans body. Next purpose is that to confirm the esthetic value of 'hair arts' by solidify the academic ground of beauty arts through creating 'hair arts' works and learning and make the direction for the beauty industry and education of the next generation. In this study I investigated the Greek myth(the background and develop)and the hair styles of ancient Greek Goddesses. On the basis of that symbols I elaborated hair formative works made of metal and studied, analyzed and displayed that. Work No.1 'Aphrodite' is the sculpture showing the win of love which animated. I formed it very active and vigorous. Next 'Birth of Venus', No.2, involves fineness and freshness. 'Fear of Medusa', the third piece, displays the very second when medusa was executed as a beautiful and active scene not a scary one. And lastly in 'Lovely Medusa' Medusa finally find the stability and it was expressed her beautiful and shining hair. So this study conducted based on the concept of practical hair and have made efforts to be close to theoretical manufacturing research needed at making hair arts works and academic one needed at organic design composition for pioneering new field, 'art hair.' I hope these 'hair arts' works make creativity of the practise hair alive. It will be very thankful to me if this study can help even though slightly for splendid beauty arts to make its status firm as a one part of arts, and there are following studies.

• 한국산업정보학회논문지
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• 제19권1호
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• pp.99-109
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• 2014

본 연구에서는 개방형 혁신을 추구하고 있는 기업 중 스마트폰 제조업체이면서 앱스토어를 직접 운영 중에 있는 애플과 삼성전자를 대상으로 IISIn model을 이용하여 플랫폼 전략을 분석 비교하였다. 앱스토어의 선도 기업인 애플은 플랫폼의 질적 강화 및 고객 충성도를 높이고 플랫폼 통제권 강화를 위해 폐쇄전략을, 반면에 후발 주자인 삼성전자는 플랫폼의 네트워크 효과 및 선순환 구조의 정착을 위해 개방형 전략을 실시 중이다. 연구 결과 지속적인 선순환 구조가 이루어지기 위해서는 우수한 플랫폼 환경과 더불어 참여자들의 자유로운 진입인 '개방'과 창출된 가치의 '공유'가 보장된 플랫폼 전략을 실시하여야 할 것으로 보인다. 본 연구는 학문적으로 IISIn model을 통하여 애플과 삼성전자의 개방형 혁신 플랫폼을 최초로 비교 분석한 연구하였다는 기여점이 있고, 실무적 측면에서는 후발기업의 개방형 혁신 플랫폼 전략수립에 도움을 줄 수 있을 것으로 기대된다.