• 제어로봇시스템학회:학술대회논문집
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• 1993.10a
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• pp.383-391
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• 1993

In this paper, a new automatic cardiac output control algorithm without any pressure sensors for the motor-driven electromechanical total artificial heart(TAH) was developed using motor current information. In the previous studies, many transducers were utilized to obtain informations of hemodynamic states for the automatic cardiac output control. But. such automatic control with sensors has some problems. To solve these problems, I proposed a new "sensorless" automatic cardiac output control algorithm providing the adequate cardiac output to the time-varying physiological demand without right atrial collapse. In-vitro tests were performed to evaluate the performance of a new algorithm and it satisfied the basic three requirements on the pump output response through the mock circulation tests.

• BMB Reports
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• v.53 no.9
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• pp.453-457
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• 2020

The right-handed double-helical structure of DNA (B-DNA), which follows the Watson-Crick model, is the canonical form of DNA existing in normal physiological settings. Even though an alternative left-handed structure of DNA (Z-DNA) was discovered in the late 1970s, Z-form nucleic acid has not received much attention from biologists, because it is extremely unstable under physiological conditions, has an ill-defined mechanism of its formation, and has obscure biological functions. The debate about the physiological relevance of Z-DNA was settled only after a class of proteins was found to potentially recognize the Z-form architecture of DNA. Interestingly, these Z-DNA binding proteins can bind not only the left-handed form of DNA but also the equivalent structure of RNA (Z-RNA). The Z-DNA/RNA binding proteins present from viruses to humans function as important regulators of biological processes. In particular, the proteins ADAR1 and ZBP1 are currently being extensively re-evaluated in the field to understand potential roles of the noncanonical Z-conformation of nucleic acids in host immune responses and human disease. Despite a growing body of evidence supporting the biological importance of Z-DNA/RNA, there remain many unanswered principal questions, such as when Z-form nucleic acids arise and how they signal to downstream pathways. Understanding Z-DNA/RNA and the sensors in different pathophysiological conditions will widen our view on the regulation of immune responses and open a new door of opportunity to develop novel types of immunomodulatory therapeutic possibilities.

• Journal of Animal Science and Technology
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• v.65 no.3
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• pp.579-587
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• 2023

In this study, rumen temperature and environment in estral and non-estral Korean Native breeding cattle were evaluated by using a bolus sensor. Behavioral and physiological changes in study animals were also assessed. To assess the rumen temperature and environment, we inserted bolus sensors into 12 Korean Native cattle with an average age of 35.5 months, then measured temperature and activity within the rumen using the wireless bolus sensor. Drinking, feeding and mounting behavior, and measured vaginal temperature and levels of intravaginal mucus resistance were recorded. We found that cattle in estrus exhibited more acts of mounting (37.4 vs. 0 times/day), increased vaginal temperature (39.0℃ vs. 38.4℃), and decreased vaginal mucus resistance (136.3 Ω vs 197.4 Ω), compared with non-estral animals. Furthermore, increased levels of rumen activity were most significant in estrus cattle at the highest activity levels (p < 0.01). Overall, the estrus group exhibited increased rumen temperature (p = 0.01), compared with the non-estrus group. In conclusion, the results of this study not only provide basic physiological data related to estrus in improved Korean Native breeding cattle, but also suggest that monitoring of rumen temperature and activity might be used as an effective smart device for estrus detection.

• International conference on construction engineering and project management
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• 2015.10a
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• pp.336-338
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• 2015

This research is to propose an applicable framework for real-time health surveillance and safety monitoring at construction sites. First this study aims at finding (1) a framework for health surveillance that is likely to benefit employers and employees in the industry, (2) a valid way to identify factors or conditions with potential health concerns that can occur under particular work conditions, (3) An effective way to apply wireless/mobile sensors to construction workers using real-time/live data transmission methods, and (4) A relationship between a worker's vital signs and job site environment. Biosensors for physiological response and devices for weather/work related data are to collect real-time data. Relationships between jobs and physiological responses are analyzed and factors that touched particularly contributing to certain responses are identified. When data are incorporated with tasks, factors affecting tasks can be identified to estimate the magnitude of the factors. By comparing work and normal responses possible precautionary actions can be considered. In addition, the study would be lead to improving (1) trade-specific dynamic work schedules for workers which would be based on various factors affecting worker health level and (2) reevaluating worker productivity with health status and work schedule, thereby seeking ways to maximize worker productivity. Through a study, the paper presents expected benefits of implementing health monitoring.

• 한국HCI학회:학술대회논문집
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• 2008.02a
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• pp.141-146
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• 2008

As the interest about ubiquitous environment is increasing, there are many researches about the services in this environment. These services have important issues in interpreting the users' context, using many kinds of sensors, like PDA, GPS and accelerometers. Low level raw data, which sensors like accelerometers calibrates, are hard to use, and to provide real-time services preprocessing and interpreting the data into context, in real-time, is important. This paper describes a context integrate system which can integrate these sensors and also sensors which has raw data, like accelerometers and physiological sensors, and define the context interpret rule with XML. The proposing system reduces programming operations when adding a sensor to the sensor network or modifying the context interpreting rule by using XML. By using this system, we implemented a real-time data monitoring system which can describe the numeric data into graphs, and assist the user to validate the data and results of the preprocess phase, and also support the external services and applications to use the context of the user.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2010.03b
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• pp.4-4
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• 2010

Multi Cultivation Remote-control System(MCRS) for crops through characteristics of multi-safe sensors was realized. It was carried out to investigate into the effect of LED Control with the physiological activity of crops(for examples, sprouts). We have also composed a Combined Automatic Control System possible for the control of temperature and humidity at the same time. And we producted the remote control as using Linux.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.14 no.3
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• pp.781-793
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• 2010

Recently, owing to the development of ubiquitous sensor network and mobile communication technologies, many studies on healthcare system are being carried out. In this paper, we have designed and implemented a mobile u-Healthcare system based on sensor network. The u-Healthcare system is composed of three components: wireless sensor network at home, healthcare center located at remote site, and gateway which relays sensing physiological signals to healthcare center. In order to measure patient's physiological signal three sensors are used: three channel ECG sensor, pulse oximeter, and blood pressure sensor. Each sensor is mounted on a mote which can send gathered signal to the base node using Zigbee communication protocol. Once the base node receives physiological signal from each sensor, the client in the base node transfers the signal to the healthcare center. The received physiological signal at the healthcare center is analyzed and processed using various algorithms. The processed results are compared to the standard healthcare database and appropriate treatment including dietetics and exercise cure would be sent to the patient as feedback using SMS message or healthcare center web site. Each patient can check and manage one's health state every day using the healthcare system and gain a recovery under the treatments from minor health problems.

• Journal of Sensor Science and Technology
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• v.24 no.5
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• pp.319-325
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• 2015

While the conventional personal protective equipments (PPEs) covers a variety of devices and garments such as respirators, turnout gear, gloves, blankets and gas masks, several electronic devices such as personal alert safety system (PASS) and heads-up displays in the facepiece have become a part of firefighters personal protective equipments through past several years. Furthermore, more advanced electronic sensors including location traking sensor, thermal imaging caerma, toxic gas detectors, and even physiological monitoring sensors are being integrated into ensemble elements for better protection of firefighters from fire sites. Despite any electronic equipment placed on the firefighter must withstand environmental extremes and continue to properly function under any thermal conditions that firefighters routinely face, there are no specific criteria for these electronics to define functionability of these devices under given thermal conditions. Although manufacturers provide the specifications and performance guidelines for their products, their operation guidelines hardly match the real thermal conditions. Present study overviews firefighter's fatalities and thermal conditions that firefighters and their equipments face. Lastly, thermal packaging methods that we have developed and tested are introduced.

• International conference on construction engineering and project management
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• 2022.06a
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• pp.855-862
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• 2022

Environmental stressors considerably influence the health and safety of humans and must thus be continuously monitored to enhance the urban environments and associated safety. Environmental stressors typically act as stimuli and lead to behavioral changes that can be easily identified. These behavioral responses can thus be used as indicators to clarify people's perceptions of environmental stressors. Therefore, in this study, a framework for assessing environmental stressors based on human behavioral responses was developed. A preliminary experiment was conducted to investigate the feasibility of the framework. Human behavioral and physiological data were collected using wearable sensors, and a survey was performed to determine the psychological responses. Humans were noted to consistently exhibit changes in the movement and speed in the presence of physical environmental stressors, as physiological and psychological responses. The results demonstrated the potential of using behavioral responses as indicators of the human perceptions toward environmental stressors. The proposed framework can be used for urban environment monitoring to enhance the quality and safety.

• Journal of Sensor Science and Technology
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• v.29 no.2
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• pp.100-104
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• 2020

Thus far, several in vivo biosensing platforms have been proposed to measure the mechanical contractility of cultured cardiomyocytes. However, the low sensitivity and screening rate of the developed sensors severely limit their practical applications. In addition, intensive research and development in cardiovascular disease demand a high-throughput drug-screening platform based on biomimetic engineering. To overcome the drawbacks of the current state-of-the-art methods, we propose a high-throughput drug-screening platform based on 16 functional high-sensitivity well plates. The proposed system simulates the physiological accuracy of the heart function in an in vitro environment. We fabricated 64 cantilevers using highly flexible and optically transparent silicone rubber and placed in 16 independent wells. Nanogrooves were imprinted on the surface of the cantilever to promote cell alignment and maturation. The adverse effects of the cardiovascular drugs on the cultured cardiomyocytes were systematically investigated. The 64 cantilevers demonstrated a highly reliable and reproducible mechanical contractility of the drug-treated cardiomyocytes. Real-time high-throughput screening and simultaneous evaluation of the cardiomyocyte mechanical contractility under multiple drugs verified that the proposed system could be used as an efficient drugtoxicity test platform.