• Journal of Korean Biological Nursing Science
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• 제16권4호
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• pp.326-333
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• 2014

Purpose: This study was to examine the effects of Nurse Presence (NP) program on anxiety and physiological indicators in patients with gynecological surgery. Methods: This study used a randomized control group pre-test, post-test design. The patients were 25-65 years old who had undergone gynecological surgery with general anesthesia. The subjects were divided into an experimental group (n=30) and the control group (n=30). SPSS 21.0 was used to analyze the data with Chi-square, Fisher's exact test, t-test, and one sample t-test. Results: The results show that there were significant differences in anxiety and heart rate and were no significant differences in systolic pressure or peripheral oxygen saturation of the experimental group which received the NP program. Conclusion: Nurse Presence program decreased pulse rate which is a physiological indicator by relieving the anxiety of the patients before gynecological surgery. Thus, this intervention is effective to relieve anxiety of the patients before gynecological surgery and should be utilized in clinics.

• 공업화학
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• 제2권1호
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• pp.56-63
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• 1991

1-(2-carbomethoxyacryloyl)-5-fluorouracil(CMAFU)을 trans-${\beta}$-carbomethoxyacryl chlocide와 2, 4-bis(trimethylsilyloxy)-5-fluoropyrimidine으로부터 합성하고, CMAFU와 메틸메타크릴레이트를 cyclohexanone을 용매로 사용하여 $60^{\circ}C$에서 라디칼공중합을 하였다. 5-FU, CMAFU 및 poly(CMAFU-Co-MMA)들이 노랑초파리에 미치는 생리유전학적 영향을 Lewis와 Bacher 방법에 의하여 조사한 결과, CMAFU와 그 중합체가 5-FU 보다 생리유전학적 영향이 약함을 알 수 있었다.

• 생명과학회지
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• 제12권6호
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• pp.740-744
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• 2002

배지의 물리성이 몇 가지 나리 품종 자구의 기내 증식과 증식된 자구의 순화에 미치는 영향을 구명하기 위해 수행되었다. 기내 인편배양과 자구배양에 의한 자구의 증식은 Oriental hybrid ‘Marco Polo’, ‘Casa Blanca’와 Asiatic hybrid ‘Jolanda’ 세 품종 모두 액체배지보다 고체배지에서 자구로부터 자구를 증식시켰을 때 형성된 자구의 수와 생장이 가장 양호하였다. 기외 순화단계에서는 모든 실험구에서 전배양이 고체배지였던 실험구가 생존율과 맹아율이 가장 높았으며, 특히 전배양에서 자구를 실험재료로 이용했던 실험구가 인편을 이용하였던 것보다 맹아율이 다소 양호하였다.

• 대한수의학회지
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• 제41권3호
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• pp.311-317
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• 2001

In this work we have investigated the physiological effects of $MgCl_2$ in isolated atrium, papillary muscle, perfused heart and anesthesized guinea pig, The addition or infusion of $MgCl_2$ (0~20 mM or mg/kg) to perfused hearts and to anesthesized guinea pigs induced a marked and dose-dependent negative chronotropic effect. The sinoatrial node automaticity could also be reduced by $MgCl_2$. The addition of $MgCl_2$to isolated atria and to papillary muscles induced a marked and dose-dependent negative inotropic effect. The threshold voltage could be increased by $MgCl_2$in papillary muscle. Increasing $MgCl_2$ shortened the action potential duration (APD) in dose-dependent manner at 30% ($APD_{30}$) and 90% repolarization ($APD_{90}$) measured with conventional microelectrode technique in papillary muscle. In anesthesized guinea pig, the magnesium infusion resulted in a dose-dependent drop in blood pressure. These results suggested that magnesium is closely associated with cardiac physiological condition and exerts antiarrhythmic activities.

• 대한의생명과학회지
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• 제23권4호
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• pp.388-394
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• 2017

Recently, coffee is the most popular beverage for modern people. A great number of substances are found in coffee beans and have been studied for many years such as aliphatic and aromatic compounds. However, studies on the physiological activity of coffee extracts are insufficient. This study was performed to determine the contents of caffeine and chlorogenic acid in coffee extracts according to the solvent and to investigate the physiological activity of coffee extracts. Coffee extracts were extracted by ultrasonication method with various types of solvents including distilled water, ethanol, and other organic solvents under $50^{\circ}C$ and $80^{\circ}C$. The contents of caffeine and chlorogenic acid in coffee extracts were determined by Liquid Chromatography-Mass Spectrometry (LC-MS). Also, cytotoxic and antioxidative effects of coffee extracts were evaluated with MTT and DPPH assays to analyze the physiological activity. As a result, it was confirmed that caffeine and chlorogenic acid contents were extracted in distilled water with the highest rate. Antioxidative activity was observed below 10-fold dilute of coffee extracts, however cytotoxicity was not observed. In conclusion, distilled water was the best solvent for extracting caffeine and chlorogenic acids from coffee bean with ultrasonication and these coffee extracts are less cytotoxic in human skin cell lines and have antioxidant effect.

• 동아시아식생활학회지
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• 제22권3호
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• pp.392-400
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• 2012

The purpose of this study was to analyze the physiological activity and antibiosis of mulberry powder by extract method. The total phenol content of mulberry powder extracted with methanol was 82.9 mg/g, while that of powder extracted with water was 46.9 mg/g. Extractions with methanol were therefore more effective than with water. The total flavonoid contents of mulberry powder extracted with methanol was 13.0 mg/g, while that of powder extracted with water was 9.4 mg/g. Also, the nitrite-scavenging ability of mulberry powder was lower than ascorbic acid and BHT. The SOD-like activity of mulberry powder extracts, natural antioxidant, and artificial antioxidant at 5 mg/mL arranged in order of decreasing concentration were ascorbic acid (98.3%) > BHT (88.1%) > water extract (9.8%) > methanol extract (3.0%). And, the OH radical scavenging activities of mulberry powder extracts and natural antioxidant at 5 mg/mL in order of decreasing concentration was ascorbic acid (97.0%) > methanol extract (46.2%) > water extract (35.8%). The antimicrobial effects of mulberry powder extracted with methanol could be detected on Bacillus cereus ($10,000{\mu}g/disc$) and Staphylococcus aureus ($10,000{\mu}g/disc$).

• International Journal of Human Ecology
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• 제14권2호
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• pp.93-103
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• 2013

This study investigated the relationship of clothing microclimate and physiological responses in order to examine the layering effects on the clothing microclimate as an index to predict clothing thermal insulation ($I_{cl}$). Experiments were conducted in a $15^{\circ}C$ environment on six physically active males. Increased clothing layers resulted in higher mean temperature inside the clothing ($\bar{T}_{cl}$) and $I_{cl}$. The $I_{cl}$ had a high correlation with: $\bar{T}_{cl}$ (r = 0.556), the difference between the innermost surface temperature and the outermost surface temperature at the chest (DST) (r = 0.549) and the temperature inside clothing at the abdomen (r = 0.478). $\bar{T}_{cl}$ had the highest correlation with the temperature inside clothing at the abdomen (r = 0.889). $\bar{T}_{cl}$ also had the highest correlation with $\bar{T}_{sk}$ (r = 0.860). The results showed that the relationship between $I_{cl}$ and $\bar{T}_{cl}$ was linear (p < .01). Thermal comfort had a negative correlation with $\bar{T}_{cl-thigh}$ (r=-0.411) and $\bar{T}_{cl}$ (r = -0.323) (p < .01.)

• 한국직업건강간호학회지
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• 제21권1호
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• pp.1-9
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• 2012

Purpose: This study was to examine the effects of the hypertension self-help program on knowledge, self-efficacy, self-management compliance, and physiological parameters for workers with hypertension. Methods: The subjects of study were 54 patients with hypertension, divided into 28 of experimental group and 26 of control group, working in a general work place located in K city from June to September, 2009. Experiment treatment was a 12-week self-care program given for two hours, once a week. Results: After conducting a self-help program, the experimental group showed significant increase in knowledge level, self-efficacy, self-management compliance, and physiological parameters including blood pressure, BMI, total cholesterol level, neutral fat, and LDL-cholesterol of blood lipids compared to the control group. Conclusion: This program is greatly recommended for workshops.

• 여성건강간호학회지
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• 제12권4호
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• pp.348-354
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• 2006

The purpose of this study was to examine the effects of an abdominal obesity management program on a woman's body composition and physiological indicators. A sample of 20 women who were 33 to 62 years old with abdominal obesity (greater than 80cm of waist circumference) participated in the program for 12 weeks. The program consisted of aerobic dance and yoga for one hour, twice a week. Their body composition was measured with BMI, body fat %, waist circumference, and waist/hip ratio. The physiological indicators were measured by systolic blood pressure, blood glucose, total cholesterol, and triglycerides before and after the program. The results showed that waist circumference, waist/hip ratio, and fasting blood glucose decreased significantly after the program. However, BMI, systolic blood pressure, and blood lipids did not change. An abdominal obesity management program with aerobic dance and yoga is partially effective in decreasing abdominal obesity. Further studies are required to replicate the study with a control group using an experimental design.

• Biomolecules & Therapeutics
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• 제10권3호
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• pp.156-164
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• 2002

In the present study, we tried to investigate whether polymerized basic amino acid e.g. poly-L-lysine (PLL) which has the degree of polymerization under 50mer significantly affects the physiological and stimulated mucin release from cultured hamster tracheal surface epithelial cells. Confluent primary hamster tracheal surface epithelial (HTSE) cells were metabolically radiolabeled with $^3{H}$-glucosamine for 24 hr and chased for 30 min in the presence of either PLLs or adenosine triphosphate (ATP) and PLL to assess the effects on basic or ATP-stimulated $^3{H}$-mucin release. Possible cytotoxicities of PLLs were assessed by measuring lactate dehydrogenase (LDH) release from HTSE cel1s during treatment. The results were as follows: PLLs significantly inhibited basic mucin release from cultured HTSE cells in a dose-dependent manner from the range of 46mer to 14mer; PLL 46mer significantly inhibited the stimulated mucin release by ATP from cultured HTSE cells; there was no significant release of LDH from cultured HTSE cells during treatment. We conclude that PLLs inhibit both physiological and stimulated mucin release from airway epithelial cells without significant cytotoxicity and PLL lost its activity under the range of 14mer. This finding suggests that polymer of basic amino acid like PLL might function as a regulator for hypersecretion of mucus manifested in various respiratory diseases.