• 제목/요약/키워드: Physical dependence

검색결과 358건 처리시간 0.028초

Ionic Conductivity in Lithium-Borate-Tantalate Compound Glasses

  • Kwon, Oh Hyeok;Yang, Yong Suk;Rim, Young Hoon
    • Journal of the Korean Physical Society
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    • 제73권12호
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    • pp.1873-1878
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    • 2018
  • We have investigated the ionic conductivity and dielectric relaxation in $Li_2B_4O_7$ (LBO) and $Li_2O-B_2O_3-Ta_2O_5$ (LBTO) glasses. The sample was synthesized by using the melt quenching method. The frequency dependence of the electrical data from the LBO and LBTO glasses has been analyzed in the frameworks of the impedance Cole-Cole formalism and the universal power-law representation driven by the modified fractional Rayleigh equation. The potential barriers in the LBO and the LBTO glasses turn out to be the same. Comparing with the dc and ac activation energies of the LBO glass, these energies of the LBTO glass decrease due to the increasing Coulomb interaction of inter-cationic interaction.

Dirac Phenomenological Analyses of 1.047-GeV Proton Inelastic Scatterings from 62Ni and 64Ni

  • Shim, Sugie
    • Journal of the Korean Physical Society
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    • 제73권11호
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    • pp.1631-1636
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    • 2018
  • Unpolarized 1.047-GeV proton inelastic scatterings from the Ni isotopes $^{62}Ni$ and $^{64}Ni$ are analyzed phenomenologically employing an optical potential model and the first-order collective model in the relativistic Dirac coupled channel formalism. The Dirac equations are reduced to $Schr{\ddot{o}}dinger-like$ second-order differential equations, and the effective central and spin-orbit optical potentials are analyzed by considering the mass-number dependence. The multistep excitation via the $2^+$ state is found to be important for the $4^+$ state excitation in the ground state rotational band for proton inelastic scatterings from the Ni isotopes. The calculated deformation parameters for the $2^+$ and the $4^+$ states of the ground state rotational band and for the first $3^-$ state are found to agree pretty well with those obtained from nonrelativistic calculations.

고순도 나이오븀과 탄탈륨 희유금속의 물리적 특성평가 (Physical Property Evaluation for High Purity Niobium and Tantalum Rare Metals)

  • 김일호;박종범;유신욱;조경원;최국선;서창열;김병규;김준수
    • 한국재료학회지
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    • 제15권4호
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    • pp.217-223
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    • 2005
  • Thermal, electrical and mechanical properties of high purity niobium and tantalum refractory rare metals were investigated tn evaluate the physical purity. Higher purity niobium and tantalum metals showed lower hardness due to smaller solution hardening effect. Temperature dependence of electrical resistivity showed a typical metallic behavior. Remarkable decrease in electrical resistivity was observed for a high purity specimen at low temperature. However, thermal conductivity increased for a high purity specimen, and abrupt increase in thermal conductivity was observed at very low temperature, indicating typical temperature dependence of thermal conductivity for high purity metals. It can be known that reduction of electron-phonon scattering leads to increase in thermal conductivity of high purity niobium and tantalum metals at low temperature.

전자파 문제에 대한 시간영역-유한차분법의 수치파 전파모델의 성질에 관한 연구 (A Study on the Numerical Wave Propagation Properties of the Finite Difference-Time Domain(FD-TD) Method for EM Wave Problems)

  • 김인석
    • 한국통신학회논문지
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    • 제19권8호
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    • pp.1595-1611
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    • 1994
  • 본 논문에서는 전자파의 전파현상의 불연속모델로서 시간영역 유한 차분법의 수치적 성질이 연구된다. 시간 공간의 차원에서 막스웰 방정식을 개구리뜀 근사식으로 나타내므로 수치적인 특성과 의존 영역의 항으로 전자파의 전파현상을 모사한다. 시간영역 유한차분법의 수치적모사과정이 기하학적으로 설명된다. 개구리뜀 근사법의 채용으로 인한 수치적인 분산현상이 예시된다. 개구리뜀 근사법을 기초로 한 시간영역 유한차분법은 원래 계산 결과만을 산출하는 모델이 아니고 묘사적인 모델이므로 전자파 전파현상에 대한 몰리적인 현상을 묘사할 뿐만 아니라 이러한 묘사직언 결과로부터 푸리에 변환을 통하여 주파수 영역에서의 결과를 추출할 수 잇는 매우 유연한 수치해석 방법이다. 그래서 본 수치해석 방법을 이용하여 WR-28과 WR-90 도파관의 E-평면 휠터와 인턱티브 아이리스의 특성성분적 결과를 포함시킨다.

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Protective Effects of Panax ginsengon the Neurotoxicity Induced by Abuse Drugs

  • Oh, Ki-Wan
    • 고려인삼학회:학술대회논문집
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    • 고려인삼학회 2005년도 창립30주년기념 추계 학술대회 및 정기총회
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    • pp.41-63
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    • 2005
  • Ginseng has been useful for the treatment of diverse disease in oriental countries for thousands of years. In addition, a folk medicine prescribed by seven herbal drugs including Panax ginseng has been antinarcotics in the treatment of morphine-dependent patients. Many articles have been reported on these works. Therefore, we review the protective effects of Panax ginseng on the neurotoxicity induced by abuse drugs. Ginseng total saponins (GTS) extracted and isolated by Panax ginseng antagonized morphine-induced analgesia, and inhibited the development of analgesic tolerance to and physical dependence on morphine. CTS inhibited morphine-6 dehydrogenase, which catalyzes production of mophinone from morphine, and increased hepatic glutathione level responsible to toxicity. Therefore, wehypothesized that these dual actions of ginseng can be associated with the detoxication of morphine. In addition, the inhibitory or facilitated effects of GTS on electrically evoked contraction in guinea pig ileum (${\mu}$-receptors) and mouse vas deferens(${\delta}$-receptors) were not mediated through opioid receptors, suggesting non-opioid mechanisms. On the hand, antagonism of U-50,488H (${\kappa}$-agonist)-induced antinociception is mediated by serotonergic mechanisms. GTS also inhibited hyperactivity, reverse tolerance (sensitization) and conditioned place preference-induced by psychostimulants such as methamphetamine, cocaine and morphine. On the other hand, GTS reduced the dopamine levels induced by methamphetamine. Moreover, GTS blocked the development of dopamine receptor activation, showing antidopaminergic effect. We suggest that GTS prevent the methamphetamine-induced striatal dopaminergic neurotoxicity. In addition, Ginsenoside also attenuates morphine-induced CAMP signaling pathway. These results suggested that GTS might be useful for the therapy of the adverse actions of drugs with abuse liability.

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암환자의 마약성 진통제에 대한 신체적 의존을 경피적 Buprenorphine 패취를 통해 성공적으로 치료한 증례보고 (Successful Treatment with Transdermal Buprenorphine Patch in Opioid-Dependent Cancer Patients: Case Series)

  • 고세일;김정훈;이경원;강정훈
    • Journal of Hospice and Palliative Care
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    • 제21권4호
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    • pp.152-157
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    • 2018
  • 암환자에서 암성 통증을 완화시키기 위한 강한 마약성 진통제의 사용이 늘어남에 따라, 마약성 진통제 관련 이상행동이 새로운 문제로 대두되고 있다. 비암성 환자에서의 마약성 진통제에 대한 중독 및 신체적 의존의 치료는 잘 알려져 있으나, 암환자, 특히 국내의 암환자에서는 이와 관련한 연구가 부족한 실정이다. 본 저자들은 강한 마약성 진통제에 대해 신체적 의존을 보여 부분 뮤-아편양 수용체 작용제인 buprenorphine으로 성공적으로 치료 받았던 열 명의 암환자들을 보고하고자 한다. 이는 암환자의 마약성 진통제에 대한 신체적 의존을 경피적 buprenorphine 패취로 치료할 수 있음을 보여준 첫 번째 보고이다.

Effect of Temperature on Dicarboxylate Transport in Plasma Membrane Vesicles of Rabbit Proximal Tubule

  • Han, Kyung-Moon;Kim, Young-Hee;Woo, Jae-Suk;Kim, Yong-Keun
    • The Korean Journal of Physiology
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    • 제27권2호
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    • pp.227-232
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    • 1993
  • The temperature dependence of $Na^+-dependent$ succinate uptake was studied in brush border (BBMV) and basolateral (BLMV) membrane vesicles isolated from the rabbit kidney cortex. The succinate uptake was markedly altered by temperature in a similar fashion in both membranes. The temperature dependence was characterized by a nonlinear Arrhenius plot with a break point at 22 and $25^{\circ}C$ for BBMV and BLMV, respectively. The activation energy was 3.91 and 17.09 kcal/mole at above and below the break point respectively, far BBMV; 2.65 and 14.05 kcal/mole, respectively, for BLMV. When temperature increased f개m 20 to $35^{\circ}C$, the Vmax of succinate transport increased from $3.49{\pm}0.11\;to\;5.90{\pm}0.86\;nmole/mg/5\;sec$ for BBMV and from $2.86{\pm}0.25\;to\;3.63{\pm}0.32\;nmole/mg/5\;sec$ for BLMV, with no change in Km in both membranes. These results suggest that renal dicarboxylate transport is similarly sensitive to a change in membrane physical state in BBMV and BLMV.

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Prediction of the Dependence of Phase Velocity on Porosity in Cancellous Bone

  • Lee, Kang-Il;Choi, Min-Joo
    • The Journal of the Acoustical Society of Korea
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    • 제27권2E호
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    • pp.45-50
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    • 2008
  • In recent years, quantitative ultrasound (QUS) technologies have played a growing role in the diagnosis of osteoporosis. Most of the commercial bone somometers measure speed of sound (SOS) and/or broadband ultrasonic attenuation (EUA) at peripheral skeletal sites. However, the QUS parameters are purely empirical measures that have not yet been firmly linked to physical parameters such as bone strength or porosity. In the present study, the theoretical models for wave propagation in cancellous bone, such as the Biot model, the stratified model, and the modified Biot-Attenborough (MBA) model, were applied to predict the dependence of phase velocity on porosity in cancellous bone. The optimum values for the input parameters of the three models in cancellous bone were determined by comparing the predictions with the previously published measurements in human cancellous bone in vitro. This modeling effort is relevant to the use of QUS in the diagnosis of osteoporosis because SOS is negatively correlated to the fracture risk of bone, and also advances our understanding of the relationship between phase velocity and porosity in cancellous bone.

유채 종자의 수본확산계수에 관한 연구 (Estimation of Effective Moisture Diffusivity of Rapeseed (Brassica napus L.))

  • ;홍상진;한재웅;금동혁
    • Journal of Biosystems Engineering
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    • 제33권5호
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    • pp.296-302
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    • 2008
  • The effective moisture diffusivity and its dependence on drying temperature during drying of rapeseed were experimentally investigated. The data were recorded from thin layer drying experiments at nine different combinations of drying air temperatures of 40, 50, and $60^{\circ}C$ and the relative humidities of 30, 45, and 60%. The moisture diffusion equation was analyzed using stepwise multiple regression analysis. Effective moisture diffusivities were calculated based on the moisture diffusion equation for a spherical shape using Fick's second law. The effective diffusivities during the drying of rapeseed were $l.72{\times}10^{-11}$, $2.41{\times}10^{-11}$ and $3.31{\times}10^{-11}\;m^2{\cdot}s^{-1}$ at 40, 50 and $60^{\circ}C$, respectively. The activation energy for moisture diffusion during drying was $28.47\;kJ{\cdot}mol^{-1}$. The dependence of moisture diffusivity on temperature was described by an Arrhenius-type equation. Drying occurred in the falling rate period and the internal moisture diffusion phenomenon is the governing physical mechanism of the moisture movement in the particles.

뇌졸중 환자 가족돌봄제공자의 영성과 삶의 질 모델: 경로분석 (Spirituality and Quality of Life Model of Family Caregivers Caring for Patients with Stroke: Path Analysis)

  • 이지영;용진선
    • 성인간호학회지
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    • 제28권6호
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    • pp.619-627
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    • 2016
  • Purpose: This study was to test a structural model of spirituality and the quality of life of stroke survivors' caregivers in order to provide guidelines for the development of intervention and strategies to improve their quality of life. Methods: Data were collected from 133 family caregivers of stroke patients who were hospitalized in C university hospital located in Seoul. Data collection using survey questionnaires was done from May, 2013 to February, 2014. Results: Fitness of the hypothetical model was appropriate. Physical component of quality of life of family caregivers is directly affected by two variables (51.5%), burden and depression. Mental component of quality of life of family caregivers is directly affected by three variables (77.6%), depression, burden, and functional dependence of patients. Depression as well as burden were directly affected by spirituality and functional dependence of patients respectively. Thus, spirituality directly affected depression and burden and indirectly affected the quality of life of family caregivers. Conclusion: Therefore, spiritual intervention to improve the stroke caregivers' quality of life might be necessary to support and strengthen their spirituality as a mediating variable that can contribute to decreasing their depression and burden.