Seo, Dae Yun;Lee, Sung Ryul;Kwak, Hyo-Bum;Seo, Kyo Won;McGregor, Robin A;Yeo, Ji Young;Ko, Tae Hee;Bolorerdene, Saranhuu;Kim, Nari;Ko, Kyung Soo;Rhee, Byoung Doo;Han, Jin
The Korean Journal of Physiology and Pharmacology
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v.20
no.3
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pp.287-295
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2016
Involuntary physical activity induced by the avoidance of electrical shock leads to improved endurance exercise capacity in animals. However, it remains unknown whether voluntary stand-up physical activity (SPA) without forced simulating factors improves endurance exercise capacity in animals. We examined the effects of SPA on body weight, cardiac function, and endurance exercise capacity for 12 weeks. Twelve male Sprague-Dawley rats (aged 8 weeks, n=6 per group) were randomly assigned to a control group (CON) or a voluntary SPA group. The rats were induced to perform voluntary SPA (lifting a load equal to their body weight), while the food height (18.0 cm) in cages was increased progressively by 3.5 every 4 weeks until it reached 28.5 cm for 12 weeks. The SPA group showed a lower body weight compared to the CON group, but voluntary SPA did not affect the skeletal muscle and heart weights, food intake, and echocardiography results. Although the SPA group showed higher grip strength, running time, and distance compared to the CON group, the level of irisin, corticosterone, genetic expression of mitochondrial biogenesis, and nuclei numbers were not affected. These findings show that voluntary SPA without any forced stimuli in rats can effectively reduce body weight and enhance endurance exercise capacity, suggesting that it may be an important alternative strategy to enhance endurance exercise capacity.
The purpose of this study was to explore the change of muscle strength, muscle endurance, flexibility and activities of daily living to develop a rehabilitational program. The subjects were selected randomly among the patients who underwent kidney transplantations at one major transplantation hospital in Seoul, Korea. This study was carried out between November 23, 1999 and February 15, 2000. The subjects in this study consisted of 16 patients who had kidney transplantations between 1 month and 12 months ago prior to this study. They were all on steroids and did not take any physical exercise regularly. The muscle strength, muscle endurance, flexibility and activities of daily living were evaluated at 1st week and after 12 weeks. The data were analyzed with numbers, percentiles, mean, standard deviation and t-test. The results were as follows: 1. After 12 weeks, the grip strength was significantly decreased than 1st week (p=.0002). 2. After 12 weeks, the back lift strength was significantly decreased than 1st week (p=.0002). 3. After 12 weeks, the muscle endurance was increased than 1st week, but it was not significant(p=.5487). 4. After 12 weeks, the flexibility was significantly decreased than 1st week (p=.0002). 5. After 12 weeks, the activities of daily living was significantly decreased than 1st week (p=.0006). Like the above result, the kidney transplant receipients' muscle strength, flexibility and activities of daily living were reduced. In order to solve this problem, the writer has found that program development to prevent the defects should be extremely required. Since now on the number of patients should expand. After the kidney transplantation, the periods of 4, 8, 12 and 16 weeks are extended. The writer proposes to examine the different phase of change in each periods.
The purpose of this study was to investigate whether two different exercises, acute exhaustive exercise and long-term endurance exercise training could affect to the expression of Mn-SOD, HSP70, and PPAR-γ protein in myocardium. The Wistar-Kyoto rats(n=24, 4 weeks) were used and randomly divided into 3 groups; endurance exercise training group (EET, n=8), acute exhaustive exercise group (AEE, n=8) or control group (CON, n=8). EET performed treadmill exercise for 12 weeks (5 days/week, 30~60 min/day). AEE exercised treadmill running (speed increased gradually to 14-26 m/min, 60 min ±10min) until exhausted when EET finished the program. Then, all the rats were sacrificed 48 hours rest at least after the last session of their own exercise program. Hearts were isolated and then the expression of Mn-SOD, HSP70, and PPAR-γ were analyzed by western blotting. One-way repeated ANOVA was used and p value under 0.05 was considered as statistical significance. The results were followed as; the expression of Mn-SOD of AEE was decreased compared with CON. However, the expression of Mn-SOD of EET was increased compared with CON. There was significant difference between AEE and EET in the expression of Mn-SOD. The expressions of HSP70 and PPAR-γ in the both AEE and EET were significantly increased compared with CON. In conclusion, acute exhaustive exercise might induce oxidative stress wheres endurance exercise training could ameliorate the oxidative conditions by increase of Mn-SOD, HSP70, and PPAR-γ. Therefore, we suggested that endurance exercise training could enhance the complementary antioxidant system and improve to prevent apoptosis. Further, a long-term moderat aerobic exercise program might play a important role in mitochondrial biogenesis in the heart.
Purpose: This study was to examine the factors (depression, level of health status, physical function, depression) influence health related quality of life (EQ5D) in community dwelling elderly according to sex. Methods: A total of 226 elderly subjects over the age of 65 years in community were included. Data were collected by measuring the physical function (muscle endurance, flexibility, balance, and cardiovascular endurance) and by using a questionnaire about EQ5D, depression, health status. Data were analyzed by SPSS 18.0 and AMOS 18.0. Results: The major findings of this study are as follows. Explained variance of EQ5D by regular exercise, physical function, and level of health status was 19% for male elderly subjects and 26.0% for female elderly subjects. The effect was different according to sex. Depression has the effect on EQ5D (${\beta}=-.356$, p<.001) in females, while the level of health status has the effect (${\beta}=.314$, p=.027) in males. Conclusion: The results of this study indicate that the effect of regular exercise, physical function, and level of health status were different on EQ5D according to sex. Thus, different health programs according to sex are necessary to increase the quality of life in elderly individuals.
Background : Treadmill training has been proposed as a useful adjunct to conventional physical therapy to restore ability to walk after stroke. The purpose of this study to inform clinical practise by evaluating the research evidence for the effectiveness of treadmill training after stroke. Methods : We searched to the effectiveness of any form of intervention for effect of treadmill training by Dankook University electronic library databases of Medline, Embase, Cinahl, Amed and PEDro combined with a hand search of papers published in relevant peer-reviewed journals. Any type of study relevant to the topic published in English during time period from 1980 to 2007 was included. Results : The literature search identified 35 studies. The included studies enrolled a total of 374 subjects. 1. Treadmill retraining without partial body weight support might be more effective than no treatment at improving gait velocity, get up and go time, gait endurance and step length symmetry. 2. Treadmill retraining with partial body weight support might be more effective than no treatment in improving step length symmetry, gait velocity, gait endurance and balance. 3. Treadmill retraining might be more effective with partial body weight support than without it at improving gait velocity and motor improvement as measured by The Stroke Rehabilitation Assessment of Movement(STREAM). 4. Treadmill retraining without partial body weight support may be no different from physiotherapy and increase gait velocity to conventional gait therapy. 5. Treadmill retraining with partial body weight support may be no different from physiotherapy for gait velocity, motor recovery and balance. Conclusion The review suggests that although treadmill training of gait, especially with partial body weight support, might Improve gait parameters and functional mobility, unless treadmill training is directed at Improving gait speed it might be no more effective than conventional physical therapy at improving gait parameters.
Kim, Myung-Chul;Han, Seul-Ki;Song, Seung-Hyun;Park, Jung-Seo
Journal of the Korean Society of Physical Medicine
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v.7
no.3
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pp.309-318
/
2012
Purpose : The purpose of this study was to compare 2 different interventions, global postural re-education (GPR) and specific spinal stabilization exercise in the healthy elderly of women. Methods : A total of 28 subjects were randomized into 2 treatment groups: GPR, where therapy involved muscle global chain stretching, or specific spinal stabilization exercise with conventional static stretching (GPR group: n=14, specific spinal stabilization exercise group: n=14). Both groups received exercise intervention 3 times a week for 12-weeks. Results : Outcome was based on trunk endurance, trunk flexibility, Pressure Bio Feedback, Oswestry Disability Index measured immediately before and after intervention. Trunk flexibility, Pressure Bio Feedback, Oswestry Disability Index improved more in GPR group after intervention. There were no differences between the 2 exercise approaches for any of the trunk endurance. Conclusion : As the above results, GPR appear to improve Trunk flexibility, Pressure Bio Feedback, Oswestry Disability Index to the elderly of women. The efficacy of the GPR program used in this study should be further investigated in a long period study and objective outcomes.
Objective: Elevated cholesterol levels contribute to changes of the arterial endothelial permeability. Hyperlipidemia promotes atherosclerosis and is associated with an increased risk of stroke incidence. The purpose of this study was to investigate the effects of having a history of hyperlipidemia prior to a stroke incidence on postural balance, anticipatory dynamic postural control, gait endurance and gait performance in individuals with hemiparetic stroke. Design: Cross-sectional study. Methods: Fifty-two adults who were diagnosed with stroke 6 months ago or more were enrolled in this study. They were divided into two different groups according to hyperlipidemia history before stroke. All participants were assessed with the Activities-specific into Balance Confidence (ABC) scale, Berg Balance scale (BBS), Dynamic Gait Index (DGI), Timed Up and Go test (TUG), and the 6-minute walk test (6MWT). An independent t-test was used to analyze the difference between the hyperlipidemia group and non-hyperlipidemia group. Results: After analysis, the BBS, TUG, and 6MWT scores were significantly different between the hyperlipidemia and non-hyperlipidemia group, but not the ABC and DGI scores. Conclusions: The results of this study show that having a history of hyperlipidemia before stroke affects static and dynamic postural balance performance, anticipatory dynamic postural balance, and gait endurance in individuals with chronic hemiparetic stroke. Based on the results of this study, we also suggest treatment for hyperlipidemia should be implemented throughout the therapeutic interventions, such as pharmacological or exercise programs, in order to restore the physical function of stroke survivors.
The purpose of this study was to verify the validation of exercise effect with loading deviation during rowing exercise. We performed evaluation of based physical fitness and joint torque before the experiment for finding muscle unbalance. So we recruited twenty four subjects who have bigger muscle strength in more 20% than average one. Subjects divided two groups. One is dominant upper limbs(DU) and the other was dominant lower limbs(DL). Subjects performed rowing exercise using electric equipment (Robo.gym.Humonic.korea). Exercise is performed four sets a day including 25 times a set, and three days a week. Measurement consist of evaluation of based physical fitness and joint torque using biodex(biodex system3.USA). Evaluation of exercise effect performed each week in joint torque of shoulder, lumbar and knee joint and each month in based physical fitness. Also we adapted 30% of 1RM for muscular endurance and 70% of 1RM for muscle strength as exercise load. The results showed that the difference of maximal peak torque were getting increase significantly during exercise. Also difference of various factor in based physical fitness were getting increase significantly except flexibility and agility. This interpreted that rowing exercise with loading deviation types could provide muscle strength and muscular endurance exercise in same time. These results could be interpret to two ways. One is effect of improving physical fitness for rowing exercise and the other meaned validation of loading deviation in rowing exercise. Our study is going to verify the validation of loading deviation during rowing and we found out that loading deviation could provide muscle strength and muscular endurance exercise for improving muscle unbalance. Our study can be used development of exercise equipment and program for normal people with muscle unbalance. Also that provide effect of whole body exercise to anybody.
Jeon, Mi-Yang;Song, Youngl-SU;Jung, Hyung-Tae;Park, Jung-Sok;Yoon, Hye-Young;Lee, Eliza
Journal of the Korea Academia-Industrial cooperation Society
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v.14
no.9
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pp.4437-4446
/
2013
The purpose of this study was to development and evaluate the effects of cardiocerebrovascular disease prevention program for taxi drivers on physiological variables(blood pressure, blood sugar, serum lipids) and physical variables(body fat, muscle endurance, cardiopulmonary endurance, balance). This study consisted of two phases: developing the program and evaluating its effectiveness. 1 phase, 321 taxi drivers investigated a health condition and a life habit and an educational need and developed a program with the ground which will reach. 2 phases, The effectiveness of the program was tested in October 2011, with 51 taxi driver. The experimental group was given 12 weeks period exercise 1 weeks 3 time, disease education 4 time, 2 nutrition consultations. Although there was no significant reduction in blood pressure, heart rate, blood sugar, serum lipids, there were statistically significant increases in muscle endurance (t=-7.62 p<.001), cardiopulmonary endurance (t=-3.39, p<.001), balance(t=-4.13, p<.001) and decreased body fat (t= -3.11, p<.015) in before compared to after. These findings suggest that an integrated cardiocerebro-vascular disease prevention program improves physical fitness.
Kim, Jong-Won;Kim, Do-Yoen;Kang, Du-Wang;Oh, Deuk-Ja
Journal of the Korea Academia-Industrial cooperation Society
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v.13
no.8
/
pp.3405-3416
/
2012
The purpose of this study was to find out the effects of music rope-skipping on health fitness, blood lipids and growth-related factors in male middle school students. For this purpose, twenty subjects were participated in this study and the participants were 'After School Class' boys in B middle school located in Gimhae City. They divided into exercise group(n=10) and control group(n=10). Exercise group conducted 45minutes per a day, four times a week for 12 weeks. And the control group continued their normal life. The results were as follows; First, in exercise group, lean body mass, muscular strength, muscular endurance, cardiovascular endurance and flexibility were all significantly increased after program execution. But %body fat was significantly decreased. In control group, muscular strength, muscular endurance and cardiovascular endurance were significantly increased. There were significant differences in lean body mass, %body fat, muscular strength and flexibility between two groups after program execution. Second, in exercise group, HDL-C was significantly increased after program execution. In control group, TG was significantly decreased. But HDL-C was significantly increased. There were no significant differences in all blood lipids(TC, TG, HDL-C and LDL-C) between two groups after program execution. Third, in exercise group, GH and IGF-I were significantly increased after program execution. In control group, IGF-I was significantly decreased. There were significant differences in IGF-I between two groups after program execution. These results indicate that music rope-skipping is effective to improve lean body mass, muscular strength, flexibility, GH and IGF-I in normal middle school male students.
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