• Journal of Applied Biological Chemistry
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• 제44권1호
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• pp.12-15
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• 2001

The antioxidative compounds and antioxidant contents of ginger (Zingiber officinale) rhizomes were determined. Substances reextracted using ethyl acetate from crude methanol extract of fresh ginger rhizome were separated through thin layer chromatography. Ten phenolic antioxidative bands were visualized through color reactions using ferric chloride-potassium ferricyanide and 1,1-diphenyl-2-picrylbydrazyl (DPPH). The antioxidative compounds were purified through preparative TLC and high performance liquid chromatography (HPLC), among which, five antioxidants were identified as 4-, 6-, 8-. and 10-gingerols and 6-shogaol on the basis of their molecular weights determined through LC-MS. As shown in experiments using DPPH free radicals, 6-Gingerol and PT4-HP8 (unknown) were revealed to be more efficient than BHT (butylated hydroxy toluene). Contents of gingerols were determined through reverse phase HPLC. Total gingerol contents (sum of 6-,8-, and 10-gingerols) in rhizomes of different ginger varieties varied significantly. The HG55 (collected at Wanju district in Korea) and the HG52 (imported from Brazil) showed the highest gingerol contents.

• The Korean Journal of Physiology and Pharmacology
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• 제6권4호
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• pp.193-197
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• 2002

In spite of abundant anatomical evidences for the fiber connection between vestibular nuclei and inferior olivary (IO) complex, the transmission of vestibular information through the vestibulo- olivo-cerebellar climbing fiber pathway has not been physiologically established. The aims of the present study were to investigate whether there are IO neurons specifically responding to horizontal rotation and also in which subregions of IO complex these vestibularly-activated neurons are located. The extracellular recording was made in 68 IO neurons and responses of 46 vestibularly-activated cells were analyzed. Most of the vestibularly-activated IO neurons responded to signals of vertical rotation (roll), while a small number (13/46) of recorded cells were activated by horizontal canal signal (yaw). Regardless of yaw-sensitive or roll-sensitive, vestibular IO neurons were excited, when the animal was rotated to the side contralateral to the recording side. The gain and excitation phase were very similar to otolithic or vertical-canal responses. Histologic identification of recording sites showed that most of vestibular IO neurons were located in ${\beta}$ subnucleus. Electrical stimulation of a HSC evoked an inhibitory effect on the excitability of the ipsilateral IO neurons. These results suggest that IO neurons mainly in the ${\beta}$ subnucleus receive vestibular signals from semicircular canals and otolithic organs, encode them, and transmit vestibular information to the cerebellum.

• 시스템엔지니어링학술지
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• 제5권2호
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• pp.27-34
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• 2009

This paper analyze technical review entry criteria and review process based on system property, and review checklist to conform technical review is also showed. The execution of review is determined according to the preparation of review item and identification for risk element. Risk level should be mitigated before technical review by appropriate plan. This paper described the entering condition of technical review for developmental phase, and tailoring consideration for technical review condition. Described technical review entry criteria, review process, and tailoring consideration is applied to development of test equipment for ground ant-air missile system. Applied system specific technical review process, tailored entry condition for test equipment for ground ant-air missile system and review check list is showed and the effectiveness of described system specific technical review process is presented.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2006년도 추계학술대회 논문집 전력기술부문
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• pp.354-356
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• 2006

This paper presents a new one-terminal numerical algorithm for fault location estimation and for faults recognition. The proposed algorithm are derived for the case of most frequent single-phase line to ground fault in the time domain. The arc voltage wave shape is modeled numerically on the basis of a great number of arc voltage records obtained by transient recorder. From the calculated arc voltage amplitude it can make a decision whether the fault is permanent of transient. In this paper the algorithm uses a very short data window and enables fast fault detection and classification for real-time transmission line protection. To test the validity of the proposed algorithm the Electro-Magnetic Transient Program(EMTP/ATP) is used.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2005년도 ICCAS
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• pp.5-10
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• 2005

We deal with the sliding mode control using the time delay estimation. The time delay estimation is able to weaken the need for obtaining a quantitative plant model analogous to the real plant so the sliding mode control with a time delay estimation (SMCTE) is very suitable for plant such as SMA actuators whose quantitative model is difficult to obtain. We have already studied the application of the time delay control (TDC) to SMA actuators in other literature. Based on the previous study on the TDC, we developed the gain tuning method for the SMCTE, which results were nearly the same as the TDC. With respect to the step response, the SMCTE proved its predominance in a comparison with other control schemes such as the PID control and the relay control. As well as the contribution of the above control methodology, the model identification for SMA actuators has also been studied. The dynamics for an SMA actuator was newly derived using the modified Liang's model. The derived dynamics showed a continuity at the change of the phase transformation process but the original Liang's model could not.

• 한국전자통신학회논문지
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• 제11권1호
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• pp.93-98
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• 2016

사건 및 사고로 다수의 피해자 또는 참고인들은 경찰서를 방문하고 진술 조서를 작성한다. 진술 조서 과정 중오기 또는 오타로 인하여 수정이 요청 되었을 때 수정 부분을 수정한 후 지문을 이용하여 수정되었음을 인정하는 불필요한 단계 과정에서 불편함과 위생적 문제점을 해결하고, 경찰의 내 수사 단계에서 진술조서 작성 시 KICS와 전자 수사자료표 시스템을 연동한 지문인식기 도입으로 원터치 신원 확인 및 간인 날인 절차를 간소화 할 수 있다.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2005년도 춘계 학술발표회 논문집
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• pp.409-416
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• 2005

Design analysis for underground spaces requires evaluating stability related to tunnel collapses. A failure mode is one of the critical factors in the conventional methods of stability analysis. Therefore identification of failure modes is essential in securing safe construction in the phase of design analysis, instrumentation planning and implementation of reinforcing measures. In this study failure modes at the tunnel heading in granular soils are investigated using physical model tests and numerical simulation for various tunnel depths and ground surface inclinations. Test results indicated that the effect of depth and inclination of ground surface on a failure mode are significant. It is identified that, with an incase in depth, failure modes become localized in a region close to the tunnel. It is also known that an increase in the inclination of ground surface results in inclined and wide failure modes.

• 한국세라믹학회지
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• 제14권3호
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• pp.163-168
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• 1977

As a wet chemical drying process "hot petroleum drying method" was applied and developed for preparing uniformly fine oxide powder with high purity and sinterreactivity. Using this method solution of sulfates was dried in hot petroleum bath (~17$0^{\circ}C$) to sulfate powder from which corresponding mullite doped by Fe3+ ion was formed. Particle size, shape, decomposition by heat, and phase identification of sulfate andoxide powders determined by DTA, TGA, X-ray diffraction, analysis and electron microscopy: sulfate powder prepared by this drying method is an intimate mixture of the amorphous form of uniformly and finely distributed spherical particles (0.05-0.1$\mu$). Mullitization with the sulfate powder occurs at 110$0^{\circ}C$ in air. The morphology of mullite particle made by firing the sulfate powder at 135$0^{\circ}C$ in oxygen atmosphere is granular of 0.1-0.3$\mu$ in size. This drying process proved to be a very effective method for preparing fine, homogeneous, and highly sinterreactive multicomponent oxide powder without conventional ceramic process of mixing, milling, and granulating. This process can be also applied for preparing electronic ceramic materials which are requisite for high purity and homogeneity.mogeneity.

• BMB Reports
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• 제49권8호
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• pp.449-454
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• 2016

Stress Granules (SGs) are microscopically visible, phase dense aggregates of translationally stalled messenger ribonucleoprotein (mRNP) complexes formed in response to distinct stress conditions. It is generally considered that SG formation is induced to protect cells from conditions of stress. The precise constituents of SGs and the mechanism through which SGs are dynamically regulated in response to stress are not completely understood. Hence, it is important to identify proteins which regulate SG assembly and disassembly. In the present study, we report Neuregulin-2 (NRG2) as a novel component of SGs; furthermore, depletion of NRG2 potently inhibits SG formation. We also demonstrate that NRG2 specifically localizes to SGs under various stress conditions. Knockdown of NRG2 has no effect on stress-induced polysome disassembly, suggesting that the component does not influence early step of SG formation. It was also observed that reduced expression of NRG2 led to marginal increase in cell survival under arsenite-induced stress.

• Biomolecules & Therapeutics
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• 제26권3호
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• pp.290-297
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• 2018

We aimed to understand the molecular changes in host cells that accompany infection by the seasonal influenza A H1N1 virus because the initial response rapidly changes owing to the fact that the virus has a robust initial propagation phase. Human epithelial alveolar A549 cells were infected and total RNA was extracted at 30 min, 1 h, 2 h, 4 h, 8 h, 24 h, and 48 h post infection (h.p.i.). The differentially expressed host genes were clustered into two distinct sets of genes as the infection progressed over time. The patterns of expression were significantly different at the early stages of infection. One of the responses showed roles similar to those associated with the enrichment gene sets to known 'gp120 pathway in HIV.' This gene set contains genes known to play roles in preventing the progress of apoptosis, which infected cells undergo as a response to viral infection. The other gene set showed enrichment of 'Drug Metabolism Enzymes (DMEs).' The identification of two distinct gene sets indicates that the virus regulates the cell's mechanisms to create a favorable environment for its stable replication and protection of gene metabolites within 8 h.