• Journal of Korean Medicine Rehabilitation
• /
• v.23 no.3
• /
• pp.37-44
• /
• 2013

Objectives The present study was designed to investigate the effects of bee venom extract pharmacopunctureon (BVP) at 肩井 (GB21) on the changes in regional cerebral blood flow (rCBF) and mean arterial blood pressure (MABP) in normal rats, and further to determine the mechanisms. Methods We purchased rats about 300g and prepared diluted BVP with normal saline. And we injected diluted BVP to rats gradually progressed from 0.001 mg/kg to 0.1 mg/kg at corresponding region to GB21. After injection, we measured the changes in rCBF and MABP of rats. In addition, to determine the mechanisms of this changes, we did the same experiments twice more after pretreatment with indomethacin and metylene blue separately. Results BVP significantly increased rCBF but decreased MABP, suggesting that BVP potently may increase rCBF by dilating pial arterial diameter. Furthermore, the increase of BVP-induced rCBF and the decrease of BVP-induced MABP were significantly blocked by pretreatment with cyclooxygenase inhibitor, indomethacin (1 mg/kg, i.p.). But the increase of BVP-induced rCBF and the decrease of BVP-induced MABP were not blocked by pretreatment with guanylate cyclase inhibitor, methylene blue (0.01 mg/kg, i.p.). Conclusions These findings indicate that the action of BVP is mediated by cyclooxygenase. Furthermore these results suggest that BVP can increase rCBF in normal state, as well as improve the stability of rCBF in ischemic state.

• Journal of Korean Medicine Rehabilitation
• /
• v.28 no.1
• /
• pp.53-60
• /
• 2018

Objectives The purpose of this study is to analyze research trends on Eastern-Western integrative medicine in Korea. Methods We searched the studies on Eastern-Western integrative medicine in 5 Korean web database (NDSL, KoreanTK, KISS, OASIS, DBPIA). 66 research papers we founded. Results 13 papers were published at 2010. The studies on Eastern-Western integrative medicine were mainly published in the Journal of Society of Preventive Korean Medicine. 24 papers were case report, include 7 studies on neurology, 4 studies on each oncology and dermatology, 2 studies on each gastroenterology and ophthalmology and otorhinolaryngology, 1 study on each obstetrics and gynecology and endocrinology and nephrology. In 24 case reports, 7 kinds of Eastern medicine treatment method and 4 kinds of Western medicine treatment method were existed. In case reports, medication (100%), herbal medicine, acupuncture (95.8%), moxibustion (58.3%), cupping, infusion solution (25%), pharmacopuncture (20.8%), physical therapy (12.5%), laser, injection, rehabilitation (8.3%) were used. Conclusions In this study, we analyzed the trends of Eastern-Western integrative medicine in korea from 2010 to 2017. There were various studies about Eastern-Western integrative medicine. In case reports, Eastern-Western integrative medicine tend to concentrated on treatment not diagnosis. Not only treatment but also diagnosis is needed in Eastern-Western integrative medicine studies.

• Journal of Korean Medicine Rehabilitation
• /
• v.28 no.1
• /
• pp.175-184
• /
• 2018

The purpose of this study is to report the effectiveness of complex Korean Medicine treatment for anterior cruciate ligament (ACL) injuries with meniscus tear. Four patients were treated with complex Korean Medicine by acupuncture, pharmacopuncture and herbal medication. We evaluated the improvement of knee pain and function by Numeric Rating Scale (NRS), Western Ontario and McMaster Universities Arthritis Index (WOMAC Index), EuroQol-5 Dimension Index (EQ-5D Index). After treatment, we found that knee pain was reduced and joint function was improved by NRS and WOMAC index in all cases. In the evaluation of health-related quality of life through EQ-5D index, there was no significant difference in patients with degenerative knee osteoarthritis and severe meniscal injury. This results show that complex Korean Medicine may be an effective option for ACL injuries with meniscus tear. Further clinical studies are needed to clarify the effect of Korean Medicine therapy on ACL injuries with meniscus tear.

• The Journal of the Society of Korean Medicine Diagnostics
• /
• v.16 no.2
• /
• pp.47-58
• /
• 2012

Objectives : The purpose of the present study is to grasp and provide basic data necessary for the establishment of korean healthcare policies in future. Methods : A questionnaire developed by the author was distributed to 299 students of D University located in Busan and collected thereafter from March 5 to June 1, 2012. Statistical processing of the data obtained was conducted using the SPSS WIN IBM 20.0 program to indicate outcomes in frequencies and percentages. Results : The results of the survey are as follows. 1. The number of students who were mainly using korean hospitals/clinics was 6(2.0%). The most important factor in selecting korean medical institutions was 'medical technology'. 2. The treatment that was received the most frequently and the most reliable at korean medical institutions was acupuncture. The most frequent reason for taking korean medicine was 'prescriptions tailored to constitutions' and the most frequent reason for avoiding korean medicine was 'high prices'. 3. There was few number of students who knew that car insurance coverage for traffic accidents include treatment at korean clinics. and who knew about 'permitted standard herbal medicine', 'the use of disposable needles', 'wild ginseng pharmacopuncture'. 4. Among items necessary for the development of korean medicine, 'treatment technology with fast and high effects' was the most frequently selected. Conclusions : University students' preference for and perception of korean medicine were shown to be very low. It is considered that public relations should be reinforced to implant correct perception of korean medicine in university students who will be major users of hospitals and clinics.

• The Journal of Internal Korean Medicine
• /
• v.34 no.3
• /
• pp.240-255
• /
• 2013

Objectives : This study was performed to research trends in Korean medicine treatment of diabetes mellitus (DM). Methods : We reviewed 73 studies about diabetes mellitus, which had been published from 2008 to 2013. The article search was performed on the Korean institute of oriental medicine (KIOM) database. Results : 1. Patterns of study design were as follows : 14 review studies, 44 experimental studies, 7 clinical studies, 8 case reports. 2. From the 14 review studies, we noted that literature studies about definition, pathologic mechanism, treatment, pathologic pattern identification of DM and previous study analyses were done. 3. From the 44 experimental studies that are the most common type of DM studies, various Korean medicine treatments such as single medicinal herbs, herbal complexes, diets and pharmacopuncture were used. Anti-diabetic effects were demonstrated in most of the studies. 4. 7 clinical studies about acupuncture, electroacupuncture, herbal medicine, etc. were reported. 5. 8 cases about DM complications and comorbidities were reported. Clinical symptoms improved in all of studies, blood sugar level decreased in four studies. Conclusions : Further clinical and case study based on experimental researches should be performed.

• The Journal of Internal Korean Medicine
• /
• v.38 no.5
• /
• pp.853-861
• /
• 2017

Objectives: The objective of this study was to report a clinical case that suggests potential beneficial effects of Korean medicine therapy for the treatment of levosulpiride-induced acute dyskinesia. Methods: A patient having drug-induced acute dyskinesia was given a series of Korean medicine therapy treatments, including administration of the herbal medicine Chengsimyeonja-tang-gamibang, acupuncture, electroacupuncture, pharmacopuncture, and moxibustion over the 17 days of the hospitalization period. During the therapy, the progression of the disease was measured by the Abnormal Involuntary Movement Scale (AIMS). Results: During the therapy, the remission of orofacial dyskinesia and improvement of AIMS scores were observed. Conclusion: Korean medicine therapy has potential benefits for the treatment of drug-induced acute dyskinesia.

• The Journal of Internal Korean Medicine
• /
• v.38 no.5
• /
• pp.797-805
• /
• 2017

Objectives: The purpose of this clinical case is to evaluate the efficacy of traditional Korean medicine as a treatment for fibromyalgia. Methods: The patient was treated with Korean medicine therapy (herbal medicine, acupuncture, pharmacopuncture, and Chu-na therapy). We measured the status and progress of this patient using a numerical rating scale (NRS), EuroQol-5D, range of movement (ROM), and a special test. Results: After the treatments, the patient's pain was controlled and the NRS score decreased. The overall symptoms of the patient and the EQ-5D score were both improved. The ROM and special test score were also improved. Conclusions: Traditional Korean medicine may have positive effects as a treatment for fibromyalgia.

• The Journal of Internal Korean Medicine
• /
• v.39 no.5
• /
• pp.1023-1031
• /
• 2018

Objectives: The purpose of this study is to evaluate the effect of Korean medicine in a patient with sensory disturbance of the hands and feet diagnosed as hereditary motor and sensory neuropathy (Charcot-Marie-Tooth disease). Methods: A patient diagnosed with hereditary motor and sensory neuropathy (Charcot-Marie-Tooth disease) was treated with herbal medicine (Uchashinki-hwan-gami, Bosinji Granule, Ukgan-san-gami), acupuncture, moxibustion, and bee venom pharmacopuncture. Clinical improvements were evaluated using the numerical rating scale (NRS) and Toronto Clinical Neuropathy Score system (TCNSS). Results: Improvements in the total scores of NRS and TCNS were observed after Korean medicine treatments. NRS score decrease from 8 to 2, and TCNS score decreased from 10 to 7. Conclusion: Korean medicine treatment may be effective for sensory disturbance in hereditary motor and sensory neuropathy (Charcot-Marie-Tooth disease).

• Journal of Oriental Neuropsychiatry
• /
• v.23 no.4
• /
• pp.11-36
• /
• 2012

Objectives : Sleep Disorders are very common in clinical stages and there are many reports and papers regarding this subject. I try to understand the present state of sleep research in JON (The Journal of Oriental Neuropsychiatry) for the benefits of clinical practice. Methods : We searched and read every article on JON from 1990 to 2012 and selected ones that are related to Sleep Disorder; then analyzed the data to 5 categories, like literature study, case study, Clinical Data-Analysis study, experimental study, and clinical trial. Results : 1. We Found 41 articles relating to sleep disorder in JON form 1999 to 2012, and there were 9 literature studies, 13 case studies, 13 Clinical Data-Analysis studies, 4 experimental studies, and 2 clinical trials. 2. There were Sa-Am Acupuncture Method, Pharmacopuncture, electroacupuncture, and Auricular acupuncture to treat Sleep Disorder. 3. There were many additional treatments like Purgative Therapy, etc. 4. They reported the ordinary sleep pattern of Soeumin and Soyangin, too. 5. In the experimental study, they reported several herbs, herbal prescription on the expression of melatonin receptors, and Punsimgeimgamibang on insomnia, anxiety, emotionality in rats. 6. There were 2 clinical trials, one for Hwabyung-patient with insomnia by acupuncture treatment and another for insomnia in the elderly by ETF-I program. 7. There were 2 case of other sleep disorder (enuresis, sleepwalking) and 2 literature study of dream. Conclusions : In JON regarding sleep disorder, the majority was due to insomnia. Therefore, we also have to expand our sight into other sleep diseases. We need more clinical trials and experimental researches for the construction of EBM Sleep Disorder in Oriental Neuropsychiatry.

• Korean Journal of Acupuncture
• /
• v.34 no.4
• /
• pp.209-230
• /
• 2017

Objectives : The aim of this study was to describe the details and to assess the clinical evidence of acupuncture and moxibustion for non-specific chronic neck pain. Methods : We searched seven databases including Korean, English, and Chinese databases through July 2016. Studies using acupuncture, moxibustion, pharmacopuncture, electroacupuncture, auricular-acupuncture, acupressure for non-specific chronic neck pain were included. Only controlled clinical trials or randomized clinical trials were assessed. Study design, number of subject, inclusion criteria, intervention, and results were extracted. In addition, details of intervention including needle type, retention time, acupoints were analyzed. Results : Total 64 studies(39 acupuncture, 9 laser, 6 pharmaco-acupuncture, 3 electro-acupuncture, 3 auricular-acupuncture, 3 moxibustion, 1 acupressure) were included. Among 39 acupuncture studies, 35 used acupuncture as sole intervention. Sham treatment was the most common intervention for control group, followed by no intervention. Various outcome including pain, disability, quality of life, range of motion was used as outcome measurement. The effect of acupuncture and moxibustion was different depending on the type of control and outcome measurement. The most commonly used method in acupuncture for neck pain was GB21, SI3, GB20, LI4, BL11 acupoints, 10~30 mm insertion depth, 20~30 retention time, and 1~2 times per week. Conclusions : Analyzing the details of acupuncture and moxibustion treatment could be helpful for researches and clinics. Further studies should consider the characteristics of study design, intervention, and outcome to assess the effect of TKM.