• 구강회복응용과학지
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• 제37권4호
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• pp.294-300
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• 2021

치태세균에 의해 야기되는 괴사성 치주질환은 감염부위에서 위막과 치간사이의 연조직 괴사 및 출혈, 촉진시 통증과 치은 출혈이 관찰된다. 환자들의 구내 세균을 조사해보면 방추균과 나선균이 혼합하여 존재하는 방추스피로헤타 세균총을 가지고 있다. 본 증례는 괴사성 치주질환으로 잠정 진단된 환자 2명을 대상으로 비외과적 치주치료, 3% 과산화수소를 적신 면봉을 이용한 드레싱 후 국소전달항생제를 도포하였고, 치료 전과 초기 치료 3 - 5일 후 치은열구액을 채득하여 실시간 연쇄중합반응법을 이용한 정량분석으로 구강내 미생물수를 측정하였다. 비외과적 치주치료 후 감염부위 치은이 정상으로 회복되었고, 7종 이상 검출되던 치주질환 관련 미생물도 1종만 검출되었다. 결과적으로 비외과적 치주치료를 통해 괴사성 치주질환 환자들의 치주 조직을 정상으로 회복하였다.

• 구강회복응용과학지
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• 제38권3호
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• pp.171-177
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• 2022

임플란트주위염은 임플란트의 주변 치조골의 상실을 동반한 치주조직의 염증성 병소이다. 임플란트주위염의 치료 목표는 자연치에서 발생되는 치주염의 치료와 유사하게, 염증을 해결하여 임플란트 주위 치주조직의 건강을 회복시키는 것이다. 치료 방법으로는 염증의 진행 정도에 따라 구강위생교육과 국소적 또는 전신적 방부제(antiseptics)와 항생제 처치를 동반한 지대주(fixture)의 mechanical cleansing, 삭제형 또는 재생형 골수술 등이 제안되고 있다. 본 연구에서, 임플란트 주위염의 표면처리(decontamination)와 삭제형골수술 이후, 특이한 골재생 증례의 6년 추적관찰 결과를 보고하고자 한다.

• 대한치과교정학회지
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• 제17권2호
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• pp.223-248
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• 1987

The early tissue reactions in the periodontal tissues of the tension zones following the application of force (30gm) to the maxillary first molar teeth of the albino rats were studied by the light microscopy and electron microscopy The increase of periodontal fibroblasts was evident, particularly in 1 day survival period. Osteoblast differentiation and new bone formation on the alveolar bone surface were occurred from 1 day survival period. Mononuclear phagocytes occurred consistently and in relatively high number adjacent to and at some distance from blood vessel Extensive breakdown of collagen fibers was observed. The increase of the phagocytosis of collagen by the active fibroblasts was evident Also, collagen fibrils were sparse or lost near the macrophage.

• Imaging Science in Dentistry
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• 제46권4호
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• pp.229-237
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• 2016

Purpose: The aim of this article is to review a group of lesions associated with periodontal ligament (PDL) widening. Materials and Methods: An electronic search was performed using specialized databases such as Google Scholar, PubMed, PubMed Central, Science Direct, and Scopus to find relevant studies by using keywords such as "periodontium", "periodontal ligament", "periodontal ligament space", "widened periodontal ligament", and "periodontal ligament widening". Results: Out of nearly 200 articles, about 60 were broadly relevant to the topic. Ultimately, 47 articles closely related to the topic of interest were reviewed. When the relevant data were compiled, the following 10 entities were identified: occlusal/orthodontic trauma, periodontal disease/periodontitis, pulpo-periapical lesions, osteosarcoma, chondrosarcoma, non-Hodgkin lymphoma, progressive systemic sclerosis, radiation-induced bone defect, bisphosphonate-related osteonecrosis, and osteomyelitis. Conclusion: Although PDL widening may be encountered by many dentists during their routine daily procedures, the clinician should consider some serious related conditions as well.

• 대한치과의사협회지
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• 제19권3호통권142호
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• pp.275-278
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• 1981

Traumatic occlusion is a morbid condition that is caused by repeated occlusal stresses exerted on the periodontium that exceed the physiologic limits of tissue tolerance and contribute to the breakdown of the supporting tissue of the teeth. In reviewing these cases, the authors obtained the following results. 1. Roentgenographic examination revealed the typical signs of traumatic occlusion: severe resorption of roots, destruction of alveolar bone. 2. The major factor of traumatic occlusion is abnormal occlusal force. 3. The rsorptions of roots and periodontal changes which are caused by traumatic occlusion depend on the individual variation of the physical potential. 4. The pathologic features of traumatism are basically different from those of inflammation.

• 대한치과의사협회지
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• 제48권9호
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• pp.664-669
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• 2010

All prosthetic and restorative therapies require a healthy periodontium as a prerequisite for success. Understanding of the concepts of periodontal-restrorative interaction, especially with regard to interactions at the gingival margin is important. The aim of this article gives the information about the essential considering factor for successful prosthesis; biologic width, periodontal biotype, width of attached gingiva, margin of restoration. If a restorative margin must be extended below the gingival margin, it is critical that adequate band of attached gingiva is present, the margin does not violate the biologic width, the margin is closed and properly finished.

• Biomolecules & Therapeutics
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• 제9권4호
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• pp.244-248
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• 2001

This study was performed to investigate therapeutic effects of Carthami Semen, Paeoniae Raidx extracts and chitosan on the growth and differentiation of human periodontal ligament cell. We found that co-treatment of methanol extracts of Carthami Semen and chitosan significantly increased the growth of human periodontal ligament cell. However, the sigle treatment groups of the extracts showed only 20-30% of the growth increase. Alkaline phosphase activity, one of differentiation markers, was increased approximately 1.5- fold by co-treatment of methanol extract of Carthami Semen and chitosan and calcified nodule formation was also increased at the similar levels as the alkaline phosphatase. But the single treatment groups showed only 20-30% increases. These results suggest that Carthami Semen and chitosan co-treatment can be used efficiently for periodontium regeneration.

• 대한치과의사협회지
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• 제9권6호
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• pp.293-296
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• 1971

Histochemical observations on the effect of gold alloys crown margin in the periodontal membrane were caried out by use of rabbits. The animal were setted with gold alloys crown on the incisor teeth. The cervical margins were given extence into gingival sockets. The animals were sacrificed at the 30 days experimented period. Specimens of tissue were obtained from the mandibular incisor teeth with jaw. All tissues were fixed immediately in 10% neutral formalin solution. Different histochemical staining methods for the determination of fibrous components were the Mallory-Heidenhain Bielschowsky-Gomori, Gomori's aldehyde fuchsin. Periodic acid-Schiff reaction and Hematoxylin eosin stanin method. The results were as follows. The periodontal membrane is composed primarily of collagenous fibers and fibrous component run functional arrangement but in lower gold content groups, horizontal fiber groups were irregularly run. Elastic fibers were obligue run in experimental groups. There were no significant differences in reticularfibers in distribution.

• 대한심미치과학회지
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• 제13권1호
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• pp.31-39
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• 2004

For the prosthodontic results which are compatible with esthetics to be fulfilled, the first prerequisite would be periodontal intervention and stability, the second one may be functional competency and the ultimate goal should be ascribed to esthetic considerations. Other words, esthetic dentistry is a whole entity which encompasses the biological stability of the periodontium, physical accuracy of the prosthodontic structure and finally, the beauty which can be found in natural dentition. It also implies the harmonized lip line which reveals the well-balanced tooth morphology and health gum profiles (Red-White Esthetics). Largely, there lie some differences in the input system of the 3-dimentional data from the prepared abutments between respective computer-assisted systems available now. But the manufacturing systems (CAM) are very similar between them, to say, comprise numeric control systems with whole 3-dimensional milling units according to the restorations to be made. Now the author is going to present CAD/CAM Zirconia All Ceramic Restoration on the topics for the Red-White Esthetics, periodontal control and maintenance, treatment for the discolored teeth, post & core build-up works for the devitalized teeth, characteristics of the Zirconium oxide All Ceramics, fabrication procedures, clinical considerations and its application to diverse clinical situations.

• International Journal of Oral Biology
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• 제35권4호
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• pp.145-151
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• 2010

Periodontitis is an inflammatory disorder of the periodontium and is characterized by destruction of the tooth supporting tissues, mediated by the upregulation of synthesis and release of a variety of pro-inflammatory factors. Inflammatory cytokines and prostaglandins upregulate RANKL and its subsequent binding to RANK stimulates osteoclast formation, resorption activity, and survival. In our present study, we investigated the effects of HP08-0111, composed of Coptis japonica (Thunb.) Makino, vitamin C and vitamin E, upon inflammatory responses, osteoclastogenesis and alveolar bone loss. HP08-0111 decreased the expression of IL-1$\beta$ and COX2 on LPS-induced RAW 264.7 cells and inhibited osteoclast-specific genes such as c-Fos, MMP-9, and TRAP. HP08-0111 also exhibited protective effects against alveolar bone loss in rats with ligature-induced periodontitis. Our results suggest that HP08-0111 is potentially an important therapeutic tool for the treatment of disorders associated with bone loss such as periodontitis.