Approximate number sense(hereafter, ANS) is the ability to compare and operate upon numerosity information. The numerosity comparison task is used to measure ANS. However, there is considerable variance among previous reports of ANS acuity which may be related to different task formats used. Here, we aim to investigate whether the format of the numerosity comparison task influences measurements of ANS acuity. We compared two task formats; 1) an intermixed format presenting two intermixed arrays of black and white dots, and 2) a side-by-side format showing two arrays of dots side by side. The intermixed format likely makes additional demands on general cognitive resources for inhibitory control, selective attention, or visuospatial working memory. The performance on the intermixed format was significantly lower than that of the side-by-side format resulting in an underestimation of ANS acuity compared to the expected trajectory of ANS development. In addition, the ANS acuity measured from only the side-by-side format was correlated with children's mathematical achievement and age. Our results demonstrate that measurement of ANS from the side-by-side format has higher construct and predictive validity compared to that of the intermixed format.
Optimal Trajectory Correction Maneuver (TCM) design algorithm has been developed using the B-plane targeting method for future Korean Mars missions. For every-mission phase, trajectory informations can also be obtained using this developed algorithms which are essential to design optimal TCM strategy. The information were computed under minimum requiring perturbations to design Mars missions. Spacecraft can not be reached at designed aim point because of unexpected trajectory errors, caused by many perturbations and errors due to operating impulsive maneuvers during the cruising phase of missions. To maintain spacecraft's appropriate trajectory and deliver it to the designed aim point, B-plane targeting techniques are needed. A software NPSOL is used to solve this optimization problem, with the performance index of minimizing total amount of TCM's magnitude. And also executing time of maneuvers on be controlled for the user defined maneuver number $(1\~5)$ of TCMs. The constraints, the Mars arrival B-plane boundary conditions, are formulated for the problem. Results of this work show the ability to design and analyze overall Mars missions, from the Earth launch phase to Mars arrival phase including capture orbit status for future Korean Mars missions
Ahn, Seung Hyun;Jun, Young min;Chang, Hak;Park, Chung Hee;Minn, Kyung Won
Archives of Plastic Surgery
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v.36
no.4
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pp.380-384
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2009
Purpose: Autologous vessels remain the gold standard for vascular grafts in microanastomoses. However, they are sometimes unavailable and have a limited long - term patency. Synthetic vessels have high success rates in large - diameter reconstructions but failed when used as small - diameter grafts due to graft occlusion. It has been proved that endothelial cell seeding improves prosthesis performance and long - term patency. Among polyurethane, PET and ePTFE, polyurethane has the best affinity to endothelial cells and mechanical properties closest to human vessels. We examined the ability of endothelial cells to attach to a polyurethane graft manufactured by the electrospinning method. Methods: Endothelial cells, which were cultured from porcine internal jugular veins, were attached to polyurethane grafts with an internal diameter of 3 mm. The same cells were attached to allogeneic decellularized porcine internal carotid artery grafts as controls. Both of the 10 mm - long grafts were exposed to endothelial cells in a well for 1 hour. Each well contained $2{\times}10^5$ endothelial cells. The graft materials were rotated through 90 degrees every 15 minutes in order to minimize the effect of gravity. The extent of cell attachment was examined with the MTT assay. Results: The MTT assay showed good incorporation of endothelial cells into both grafts. For the evaluation of affinity, the number of attached cells was counted at 10 fields of microscopic examination with ${\times}40$ magnification. Endothelial cells adhered more to polyurethane grafts (mean, $127.4{\pm}6.2cells$) compared to porcine artery grafts (mean $45.8{\pm}5.1cells$)(p<0.05,Mann - Whitney test). Conclusion: In this study, we attached porcine endothelial cells to polyurethane grafts, manufactured by electrospinning. The grafts exhibited a better affinity to endothelial cells than allogeneic decellularized porcine internal carotid artery grafts. It is suggested that the time required for endothelial cells to attach to decellulized artery grafts may be longer than that which is required for attachment to polyurethane grafts.
To know the effect of index of social ability (ISA) and function of social life (FSL) with activities of daily living (ADL) and instrumental activities of daily living (IADL), we carried out a study on the elderly with osteoarthritis daily living in Daegu city for 4 months, from April to July 2002. The followings were observed: 1. The score of functional disability of knee, ADL and ISA were better at lower age (p < 0.01). 2. The younger they are, the better FSL they have. The lower age group has good FSL (p < 0.01). 3. Weight affects more to the under 49Kg group than 50-59Kg group and 60-69Kg group in functional disability of knee, while it doesn't make much difference for the other groups (p > 0.05) and other assessment index doesn't show any relationship with weight. 4. Regarding relat ionship with height , taller group has better knee functions: it's proved by post hock examination that the over 160cm group has much higher knee function than the other groups (p < 0.05). In case of ADL, the over 160cm group and under 149cm group were better than 150$\∼$159cm group. (p < 0.01) . 5. ISA was also different depending on height . It was proved that FSL was the better for the over 160cm group than for the others as a result of post hock examination (p < 0.05). 6. In regard of how many months have passed since the attack of functional disability of knee, knee joint function was better for the 12mon$\∼$36mon group than for the others and the score of ADL was lower for the 12mon$\∼$36mon group than for the others (p < 0.01). ISA was lower for the 12mon$\∼$36mon group and the under 6mon group than for the other groups (p < 0.01). FSL was lower for the 12mon$\∼$36mon group and the under 6mon group than the other groups. (p < 0.01). 7. Comparing left knee with right one, the problem with left knee has lower score of functional disability in all items (p < 0.01). 8. Considering friction noise, knee joint function was slightly better for non-friction noise-group, but it's not statistically significant though. ADL and ISA were better for non-friction noise-group (p < 0.01), while no statistical significance was found in FSL, 9. Knee joint function was better for the group who doesn't have limitation on range of knee flexion motion (p,0.05) but no other difference was found in other items from this group. 10. Limitation on range of knee flexion motion has no statistical difference in ADL and FSL. However, ISA was better for the non-limitation group (p < 0.05) . 11. Knee joint function score has high correlation with ISA (r=0.812, p < 0.01) and FSL (r=0.732, p < 0.01) , which shows the better knee joint function, the higher the score. 12. ISA and FSL were highly correlated: the better ISA, the better FSL (r=0.893, p < 0.01), while ADL has no correlation with either knee joint function or ISA or FSL.
Numerosity perception is considered as an innate ability of human being where its sensivitiy may widely vary across each individual person. The present study explored the relationship between visual working memory (VWM), visual search efficiency, and numerosity sensitivity. To accomplish this, we calculated each participant's K-value from change detection performance representing one's storage capacity in VWM, slopes of search RTs representing the search efficiency, and discrimination sensitivity for a quantity difference across two sets of dot arrays representing the numerosity sensitivity. The correlational analysis across the measurements revealed that participants with a high VWM capacity better discriminated the numerosity difference in the arrays when the spatial information in the two dot arrays was preserved. In contrast, the participants with high search efficiency discriminated better the difference in the arrays when the spatial information in the arrays was not preserved. The results indicate high VWM-capacity individuals were presumably able to use a strategy of storing the dot arrays by grouping them into a smaller pattern of dot arrays while high search-efficiency individuals were able to use a strategy of rapidly switching their focused attention across the dots in the arrays to count each individual dot. These in sum suggest that individual differences in numerosity sensitivity rely on one's working memory capacity as well as their efficient use of switching focused attention.
Kim, Hyunwook;Phee, Young Gyu;Roh, Young Man;Won, Jeoung Il
Journal of Korean Society of Occupational and Environmental Hygiene
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v.9
no.1
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pp.99-111
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1999
The purpose of this study was to evaluate crystalline silica contents in airborne respirable dusts from various manufacturing industries and to compare analytical ability of two different methods of quantifying crystalline silica, X-ray diffraction(XRD) and Fourie transform infrared spectroscopy(FTIR). Various manufacturing industries with a history of having pneumoconiosis cases and also known to generate dusts containing crystalline silica were investigated. These industries include: ceramics, brick, concrete, and abrasive material etc. The personal respirable dust samples were collected using l0mm, Dorr-Oliver nylon cyclone equipped with 37mm, $5{\mu}m$ pore size. polyvinylchloride (PVC) filters as collection media. All samples were weighed before and after sampling and were pretreated according to the NIOSH sampling and analytical methods 7500, and 7602 for dust collection and quartz analysis. A total of 48 samples were collected from these industries. Initial analyses of these samples showed log-normal distributions for dust and quartz concentrations. Some results from ceramics and stone exceeded current Korean Occupational Exposure Limits. The average concentrations of personal respirable dust by cyclone were 0.43, 0.24, 0.26, 0.42, 0.53 and $0.29mg/m^3$ in ceramics, stone, concrete, glass, briquets, and others, respectively. A comparison of performance of two analytical methods for quantifying crystalline silica was performed using data from ceramics. The results showed that no significant difference was found between two methods for ceramics. The mean crystalline silica contents determined by XRD were 3.41 % of samples from briquets and 7.18 % from ceramics and were 2.58 % from concrete and 10.33 % from ceramics by FTIR. For crystalline silica analysis, two analytical techniques were highly correlated with $r^2=0.81$ from ceramics. Both cristobalite and tridymite were not detected by XRD and FTIR.
Kim, Na-Young;Kim, Hwan;Kim, Juk-Young;Kwon, Young-Mi
Journal of Internet Computing and Services
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v.12
no.5
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pp.21-28
/
2011
Recently medical and entertainment applications using conducting textile are suggested, but the data of conducting threads are not characterized, classified and verified. Only the data sheet published by manufacturing companies is available. Thus we need to verify the performances of the threading threads in communication. And we need a guideline if the existing communication protocols can be used for the conducting threads communication or the new specific communication protocols have to be developed for the communication. This paper classifies the characteristics of conducting threads made by domestic and overseas companies. Based on the criteria we classified conducting threads into three classes: class A, class B and class C. Further we carried out experiments to verify the adaptability of existing simple serial communication protocols such as RS232. Six different conducting threads are used in experiments and the length of each thread was 0.5m, 1m, 2m and 3m. The data transmission rate and error rate are collected and analyzed. RS485 is very prone to error due to static electricity from human and environment. So it may not be appropriate as long-distance communication protocol up to 12km which is possible in theory. RS232 shows stable and error-less data transmission ability even though every conducting thread didn’t show transmission capability over RS232. USB protocol shows high data rate transmission but the distance cannot be exceeded over 2m. Additionally, USB requires stable power supply. But if the power is supplied through conducting thread, its function is not.
Problems appear when triptans are taken orally. For example, the bioavailability of triptan is reduced by the digestive system, and the drug level in the blood reduces rapidly over time; there is also a possibility of gastrointestinal disorder. To improve side effects, a transdermal patch has been prepared in hydrogel form. The polymer matrix that makes up the hydrogel uses PVA; PEG is used as an additive to induce inter/intra hydrogen bonding of the PVA and almotriptan drug is added. In addition, to accelerate micro-phase separation between PVA chains, liquid nitrogen is used. In FT-IR analysis, the absorption bands of PVA, PEG, and almotriptan were found. The degree of crystallinity, the water uptake ability and tensile strength were increased with increasing PEG content. In drug release tests, the amount of drug released increased depending on the PEG content. In this study, hydrogels with 10 wt% PEG showed better performance in drug release. Approximately 60% of the total drug amount was released in 2 hr, and the drug continued to release for 1 day. Thus, the prepared hydrogel patch is suitable as a transdermal formulation for the second dose administration of triptans to patients who require recurrent migraine treatment within 24 hr after the first administration.
Proceedings of the Korean Radioactive Waste Society Conference
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2009.06a
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pp.187-187
/
2009
Opening of fractures induced by shear dilation or normal deformation can be a significant source of fracture permeability change in fractured rock, which is important for the performance assessment of geological repositories for spent nuclear fuel. As the repository generates heat and later cools the fluid-carrying ability of the rocks becomes a dynamic variable during the lifespan of the repository. Heating causes expansion of the rock close to the repository and, at the same time, contraction close to the surface. During the cooling phase of the repository, the opposite takes place. Heating and cooling together with the, virgin stress can induce shear dilation of fractures and deformation zones and change the flow field around the repository. The objectives of this work are to examine the contribution of thermal stress to the shear slip of fracture in mid- and far-field around a KBS-3 type of repository and to investigate the effect of evolution of stress on the rock mass permeability. In the first part of this study, zones of fracture shear slip were examined by conducting a three-dimensional, thermo-mechanical analysis of a spent fuel repository model in the size of 2 km $\times$ 2 km $\times$ 800 m. Stress evolutions of importance for fracture shear slip are: (1) comparatively high horizontal compressive thermal stress at the repository level, (2) generation of vertical tensile thermal stress right above the repository, (3) horizontal tensile stress near the surface, which can induce tensile failure, and generation of shear stresses at the comers of the repository. In the second part of the study, fracture data from Forsmark, Sweden is used to establish fracture network models (DFN). Stress paths obtained from the thermo-mechanical analysis were used as boundary conditions in DFN-DEM (Discrete Element Method) analysis of six DFN models at the repository level. Increases of permeability up to a factor of four were observed during thermal loading history and shear dilation of fractures was not recovered after cooling of the repository. An understanding of the stress path and potential areas of slip induced shear dilation and related permeability changes during the lifetime of a repository for spent nuclear fuel is of utmost importance for analysing long-term safety. The result of this study will assist in identifying critical areas around a repository where fracture shear slip is likely to develop. The presentation also includes a brief introduction to the ongoing site investigation on two candidate sites for geological repository in Sweden.
Objectives : Dementia has emerged as a leading public health problem in elderly persons, and its early detection is important for the treatment of curable cases, and in the educational support for other family members. Although dementia screening tests are available, they have not gained widespread use in community or primary care settings. Our goal was to validate the Tine and Change (T&C) Test, -including its validity and reliability in patients, and to assess it as a simple, standardized method for the screening of dementia in the rural elderly. Methods : The participants in this study comprised of 59 patients from an urban hospital and 405 persons from a rural community aged 65 years or older. The time test evaluated the understanding of clock hands indicating 11:10, and the change test the ability to make 1,000 Won from a group of coins, consisting of one 500, seven 100, and seven 50 Won coins. The T&C ratings were validated against a reference standard based on the physician's diagnosis of the patients. The convergent validity in relation to other cognitive measure, test-retest agreement, and inter-observer reliability were assessed. To assess the relationship between the Korean Mini-Mental State Exam (K-MMSE) and the T&C Test, the mean K-MMSE scores were compared with the results of the T&C Test in the elderly from a rural community. Results The T&C Test had a sensitivity and specificity of 73.0, and 90.9%, and positive and negative predictive values of 93.1, and 66.7%, respectively. The test-retest and inter-observer agreement rates were both 95%. The K-MMSE scores and T&C Test were significantly related in the elderly from a rural community (p<0.01), The T&C Test was not influenced by the educational status. The Time and Change Tests took a mean of 6.3 and 12.7 seconds, respectively, to complete Conclusion : The T&C Test is a simple, accurate and reliable, performance-based tool in the screening for dementia. Because it is quick, and easy-to-use, it is hoped the T&C Test will be used for the widespread cognitive screening of aging populations.
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