• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.27 no.5
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• pp.286-297
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• 2024

Purpose: Liver cirrhosis is a major cause of hospital admission and mortality among children. Understanding the factors that influence disease severity is essential for preventing and reducing mortality. This study explored the association between hemoglobin levels and liver disease severity in children with cirrhosis. Methods: This cross-sectional study included 326 children with cirrhosis admitted to Namazi Teaching Hospital between 2015 and 2020. Clinical data, Child-Turcotte-Pugh (CTP) scores, and pediatric end-stage liver disease/model for end-stage liver disease (PELD/MELD) scores were collected to assess disease severity. Anemia was defined based on age, sex, and hemoglobin levels. Results: Among the children with cirrhosis, 275 (84.4%) were anemic, with a mean age of 5.4±4.8 years. The overall mean hemoglobin level was 9.2±2.1 g/dL. A significant inverse correlation was observed between hemoglobin levels and CTP and PELD/MELD scores in children with anemia (p<0.001). Moreover, lower hemoglobin levels were associated with more higher CTP classes (p<0.001). Conclusion: According to the data analysis, a significant correlation was observed between hemoglobin level and the severity of liver disease, and hemoglobin level decreased with increasing severity of liver disease. According to CTP class, the mean hemoglobin level decreased progressively as the disease progressed. A comparison of the mean CTP scores between children with and those without anemia revealed that those with anemia had more severe disease than those without anemia.

• Journal of the korean academy of Pediatric Dentistry
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• v.34 no.3
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• pp.454-460
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• 2007

Traumatic dental injuries in childhood and adolescent occurred more frequently than in adult. The time between the accident and the treatment is one of the most critical factors to prognosis, and because of the limited time available to examine and treat patients with traumatic dental injuries, if not treat appropriately, the result would be critical for the patient. In the previous studies, the prevalence and incidence of traumatic injuries were the most frequent at the age of 8 to 10 years, the majority of dental injuries involve the anterior teeth, especially the maxillary incisors, and males were more prevalent than females in an approximated proportion of 2:1. As the mean age of complete root formation is 10 years old, the maxillary permanent incisor involved in the most affected age group is usually immature, and the possibility of pulpal healing through excellent revascularization exists, more positive prognosis for pulp vitality would be expected. These are treatment cases of the immature maxillary permanent central incisor involved in the traumatic injury, and reports for progress and results of preserving the pulp vitality through the conservative treatment instead of the conventional endodontic root therapy.

• Journal of the korean academy of Pediatric Dentistry
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• v.31 no.1
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• pp.108-113
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• 2004

This study was to evaluate and compare differences of the cervical vertebral skeletal maturity of normal occlusion and skeletal Class III malocclusion. Normal occlusion (172 girls) and skeletal Class III malocclusion(191 girls) were classified according to diagnosis stone model and lateral cephalogram of Korean girls aging from 8 to 12 years. The concavity of inferior border, vertico-horizontal ratio of cervical vertebrae were observed and measured according to age. Differences of the cervical vertebral skeletal maturity were evaluated. The results were as follows : 1. The concavity of inferior border of the 2nd to 6th vertebrae of normal occlusion and skeletal Class III had uniformly increased with age. 2. The vertico-horizontal ratio of the 3rd to 6th vertebrae of girls with normal occlusion and skeletal Class III had uniformly increased with age. 3. There was no significant difference in cervical vertebral skeletal maturity between normal occlusion and skeletal Class III malocclusion in the concavity of inferior border of the 2nd to 6th vertebrae and in the vertico-horizontal ratio of the 3rd to 6th vertebrae. The results in the study indicate that there is no significant difference of cervical vertebral skeletal maturity between girls with normal occlusion and skeletal Class III malocclusion.

• Journal of the korean academy of Pediatric Dentistry
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• v.30 no.1
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• pp.92-101
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• 2003

Under this thesis, 235 patients with dental problems treated under general anesthesia at the Pediatric Dentistry Clinic of Yonsei Dental College were surveyed and their age distribution, reasons for taking general anesthesia, duration of anesthesia, duration of dental procedure, dental treatment peformed and complications were analyzed. A questionnaire survey was also conducted to analyze degrees of anxiety and satisfaction among their parents according to the parents' age, educational background and experience of general anesthesia, as well as the patients' age and past dental history. Following are the results. 1. When the patients were treated under general anesthesia, the degree of anxiety of their mothers was higher than that of their fathers. It appeared that the higher the parents' educational background was, the less their anxiety. 2. The higher the parents' educational level was, the higher the degree of satisfaction after treatment under general anesthesia. 95 cases (87.2%) responded that they would accept such treatment again, if needed. From the result, dental treatment under general anesthesia causes anxiety for parent but the parent's satisfaction level was high. And that was the way gives good quality of dental service to unmanagable patients.

• Journal of the korean academy of Pediatric Dentistry
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• v.29 no.2
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• pp.189-195
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• 2002

In the area of pediatric dentistry, several behavior modification techniques have been attempted to relieve young patients' dental fear. The use of audio-visual(AV) aids is one of them and is increasing. In this study, several patients' reactions to dental treatment have been investigated after using AV aids, including patients' sleep, movement, crying and overall behavior. The effectiveness of AV aids have also been investigated through patients' age, previous dental experience and daily exposure to TV or video. Thirty healthy children with Frankl behavior rating (+) or (-) were included in this study. The average age of the children was $52.9{\pm}12.7$ months and no statistical difference was found between the two groups. Thirty patients were equally divided into two groups. Group I(control) received dental treatment with the conventional tell-show-do while group II(AV) with tell-show-do and AV aids. All patients received only restorative dental treatment and received no extraction. Houpt behavior rating scale was used to evaluate patients' behavior during the dental treatment. As a result, there was no significant difference between the two groups in movement and crying. However, more patients in the AV group fell asleep during the dental treatment compared to the control group. Within the AV group, patients with previous dental experience, older age and frequent exposure to AV materials showed better overall behavior during the dental treatment as audio-visual aids were used for behavior management.

• Journal of the korean academy of Pediatric Dentistry
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• v.37 no.3
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• pp.328-337
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• 2010

The purpose of this study was to research the traumatized primary teeth and investigate following factors: sex, age, cause, place and time(of the year) of injury, elapsed time, area and type of injury, dental treatment and prognosis. The analysis includes total of 1533 traumatized primary teeth from 758 children aging from 6 months to 6 years(mean age: 2.8) from 2003 to 2007. The result follows : 1. The children of age between 1-2 and 2-3 were involved in the largest number of injuries in both sexes with boy/girl ratio of 1.77:1(p<0.001). 2. Fall and collision were the main causes of traumatic dental injury, especially in younger children(p<0.05). Places of injury occurrence varied: home, outdoors, and kindergarten. Warm climate accounts for frequent outdoor injuries in May, September and October(p<0.001). 3. Most of the children visited dental clinic within 24 hours of the injury(77.6%). From March to September, dental trauma occurrences were distributed evenly, except for Winter period(p<0.001). 4. Upper central incisors were the most commonly affected teeth, and the injuries usually involved 1 tooth or 2 teeth. 5. Periodontal tissue injuries dominated and subluxation was the most common type. Lateral luxation, enamel fracture, intrusion and root fracture followed.

• Journal of the korean academy of Pediatric Dentistry
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• v.32 no.3
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• pp.461-471
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• 2005

The purpose of this study is to develop soft tissue cephalometric standards in children with normal occlusion and to determine the differences between males and females and the differences according to age ranges of 9, 10 and 11 years. The lateral cephalometric radiographs of 169 children(82 boys, 87 girls) among the contestants in 2000-2004 Healthy Dentition Contest in Seoul were studied with several soft tissue profile analyses and cephalometric means and following results were obtained. 1. The sex differences were not statistically significant between males and females soft tissue parameters except for two soft tissue parameters(p>0.05). 2. Females had relatively more protrusive lower lip relative to the H line than males and middle third face height to lower third face height of females was larger than males(p<0.05). 3. The age differences in soft tissue parameters were not statistically significant according to age ranges of 9, 10 and 11 years(p>0.05).

• Journal of the korean academy of Pediatric Dentistry
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• v.46 no.3
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• pp.310-317
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• 2019

The purpose of this retrospective study was to evaluate the survival rate of composite resin restorations in permanent first molars in pediatric patients focusing on the influence of risk factors related to patients and teeth. 172 patients (6 - 12 years old) who had their permanent first molars restored with composite resin from July 2010 to July 2012 were investigated. From the dental records, the influence of the risk factors on the survival of restorations was assessed. Location of teeth, classification of cavities, patients' age and caries risk were included as risk factors in this study. The caries risks of patients were evaluated by the value of the decayed-missing-filled teeth index with the records of patients taken at 5 years old. Among 354 restorations, 272 restorations retained and 82 restorations were replaced. The overall cumulative survival rate at 5 years was 73.9%. The main reason for replacement of restorations was secondary caries (81.7%). Patients with older age group and with lower caries risk group showed higher survival rate of restorations. No statistically significant influence was detected between the survival rates and the possible risk factors : location of teeth, patients' age and caries risk. The survival rate of restorations was significantly affected by the classification of the cavities (p = 0.002).

• Annals of Pediatric Endocrinology and Metabolism
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• v.23 no.4
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• pp.210-214
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• 2018

Purpose: Premature adrenarche (PA) often leads to polycystic ovary syndrome (PCOS). Higher anti-mullerian hormone (AMH) levels are reported in PCOS. We studied the androgen profile and AMH profiles in Hispanic girls with PA (aged 5-8 years) and age and body mass index (BMI) matched controls. Methods: Retrospective review of electronic medical records of girls who met the inclusion criteria for premature adrenarche were done. Results: PA girls (n=76) were matched to control girls (n=12) for age (mean${\pm}$standard deviation) ($6.7{\pm}1years$ vs. $6.2{\pm}1.3years$) and BMI ($20{\pm}10kg/m^2$ vs. $17.8{\pm}2.7kg/m^2$). Dehydroepiandrostenedione sulfate ($63.3{\pm}51.3{\mu}g/dL$ vs. $29.8{\pm}17.3{\mu}g/dL$, P<0.001) and testosterone levels ($11.4{\pm}4.8ng/dL$ vs. $8.2{\pm}2.9ng/dL$, P=0.001) were significantly higher in the PA group than controls. AMH values (<14 years: reference range, 0.49-3.15 ng/mL) were $3.2{\pm}2.2ng/mL$ vs. $4.6{\pm}3.2ng/mL$ respectively in the PA and control groups and were not different (P=0.4). AMH did not show a correlation with bone age (P=0.1), and testosterone (P=0.9) in the PA group. 17-hydroxyprogesterone levels (17-OHP ng/dL) were $39.5{\pm}30.5ng/dL$ vs. $36.8{\pm}19.8ng/dL$ in PA versus control girls. The concentration of 17-OHP was not statistically different between the control and PA groups. Conclusion: Higher AMH was not observed in PA girls and no correlation with BA and androgen levels was observed.

• Journal of the Korean Society of Radiology
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• v.83 no.1
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• pp.138-148
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• 2022

Purpose This study evaluated the rates and annual trends of pediatric CT scans in South Korea using a nationwide population-based database. Materials and Methods Data regarding pediatric CT scan usage between 2012 and 2017 were retrieved from the health insurance review and assessment service. Data on the age, sex, diagnosis, and the anatomical area of involved patients were also extracted. Results A total of 576376 CT examinations were performed among 58527528 children aged below 18 years (9.8 scans/1000 children), and the number of CT examinations per 1000 children was noted to have increased by 23.2% from 9.0 in 2012 to 11.0 in 2017. Specifically, the number of CT examinations increased by 32.9% for the 6-12 years of age group (7.4/1000 to 9.8/1000) and by 34.0% for the 13-18 years of age group (11.4/1000 to 15.3/1000). Moreover, majority of the CT scans were limited to the head (39.1%), followed by the extremities (32.5%) and the abdomen (13.7%). Notably, the number of extremity CT scans increased by 83.6% (2.3/1000 to 4.2/1000), and its proportion as compared to other scans increased from 25.3% to 37.7%. Conclusion CT scans in the pediatric population increased continuously from 2012 to 2017 at an annual rate of 4.4%. Therefore, physicians should balance the benefits of CT with its potential harms from associated radiation exposure in pediatric patients.