• 대한토목학회논문집
• /
• 제28권5A호
• /
• pp.673-683
• /
• 2008

본 연구는 PSC I 거더교량을 대상으로 포장층에 축감지기가 없이 오로지 교량 상부구조 하면에서 측정한 변형률 신호만을 이용하는 차량하중분석시스템 개발에 관한 것이다. 중 차량이 교량을 주행할 때 교량 바닥판에서 측정한 변형률 신호로 차량주행정보를 추출하고, 교량 거더 및 가로보에서 측정한 변형률 신호로 차량하중정보를 추출하는 방법이다. 이러한 정보 분석을 위하여 영향선 분석방법과 인공신경망 분석방법을 사용하였다. 학습 데이터 확보 및 시스템 검증을 위하여 임의차량 및 시험차량 주행시험을 실시하였다. 대상 교량에서 하중분석결과, 가로보 변형률 신호를 이용한 경우가 거더 변형률 신호를 이용한 경우보다 더 정확한 결과를 나타내었고, 차선당 2열로 설치된 교량 바닥판 슬래브의 변형률 신호를 이용한 피크 검출 알고리즘도 차량의 속도와 축 수, 주행 차선, 축간 거리, 차간 거리 등의 주행정보를 추출하는데 매우 효과적임을 확인하였다. 또한, 가로보의 변형률 신호를 가지고 인공신경망 학습을 하여 시스템을 구성할 수 있는 경우가 기존의 거더 변형률 신호와 영향선만으로 시스템을 구성하는 경우보다 더 정확한 결과를 얻을 수 있음도 확인 하였다.

• 한국항만학회지
• /
• 제13권1호
• /
• pp.113-122
• /
• 1999

Congestion and traffic accidents occur on the merge and diverge sections in the interchange of the freeway. Studies have been conducted to reduce the traffic delay and accidents on the merge section in the freeway since 1960s. but a study was not conducted to estimate the speed variation on the merge section construct models estimated for the speed variation and suggest the appropriate measures. The purpose of this study was to identify the traffic flow characteristics on the merge section in the freeway construct the models estimated for the speed variation on the merge section in the freeway and finally establish the appropriate measure for reduction of traffic delay and accidents on the merge section in the freeway. The following results were obtained: I) Speed variations in the urban freeway appeared to be about 3.2mph, 6.5mph and 7.4mph based on the morning peak period, afternoon peak period and 24-hours period but those in the suburban freeway appeared to be about 8.0mph, 11.1mph and 10.1mph based on the same periods respectively. So different speed reduction signs need be installed to reduce delay and accidents on the merge section in the freeway based on the areas and periods as the freeway traffic management system(FTMS). ii) These models estimated for speed variation need to be studied with the changeable message sign(CMS) technique based on the real-time data so that the traffic flow could be maximized and the traffic delay and accidents be on the merge section in the freeway as more efficient freeway traffic management system(FTMS) in the near future.

• Journal of Pharmaceutical Investigation
• /
• 제33권1호
• /
• pp.51-53
• /
• 2003

This study was conducted to compare the bioavailability of a generic product of Sinil Atenolol Tablets (Sinil Pharmaceutical Co., Ltd., Korea) with the innovator product, $Tenormin^{\circledR}$ Tablets in 20 healthy Korean volunteers. The volunteers received a single 50 mg dose of each atenolol formulation according to a randomized, two-way crossover design. Plasma samples were obtained over a 24-hour interval, and atenolol concentrations were determined by HPLC with a fluorescence detector. From the plasma atenolol concentration vs time curves, the following parameters were compared: area under the plasma concentration-time curve (AUC), peak plasma concentration $(C_{max})$, time to reach peak plasma concentration $(T_{max})$, and terminal first order elimination half-life $(t_{1/2})$. No statistically significant difference was obtained between the $T_{max}$ values, and the logarithmic transformed AUC and $C_{max}$ values of the two products. The 90% confidence for the ratio of the logarithmically transformed AUC and $C_{max}$ values of Sinil Atenolol Tablets over those of $Tenormin^{\circledR}$ Tablets were calculated to be between 0.99 and 1.07, and 1.04 and 1.16, respectively; both were within the bioequivalence limit of 0.80-1.25. The mean of $T_{max}$ in $Tenormin^{\circledR}$ Tablet group was 3.68 hour, and that in Sinil Atenolol Tablet group was 3.65 hour. The values of $t_{1/2}$ between the two products were found comparable, and the mean $t_{1/2}$ values of $Tenormin^{\circledR}$ Tablets and Sinil Atenolol Tablets were 5.9 and 6.0 hour, respectively. Based on these results, it was concluded that Sinil Atenolol Tablets were comparable to $Tenormin^{\circledR}$ Tablets in both the rate and extent of absorption, indicating that Sinil Atenolol Tablets were bioequivalent to the reference product, $Tenormin^{\circledR}$ Tablets

• 한국임상수의학회지
• /
• 제34권5호
• /
• pp.330-334
• /
• 2017

The aim of this study was to establish an injection protocol of a test bolus and a main bolus of contrast material for computed tomographic pulmonary angiography (CTPA) for visualizing optimal pulmonary arteries in normal beagle dogs. CTPA using a test bolus method from either protocol A or B were performed in each of four normal beagle dogs. In protocol A, CTPA was conducted with a scan duration for around 8 s, setting the contrast enhancement peak of the pulmonary trunk in the middle of the scan duration. The arrival time to the contrast enhancement peak was predicted from a previous dynamic scan using a test bolus (150 mg iodine/kg) injected with the same injection duration using for a main bolus (450 mg iodine/kg). In protocol B, CTPA was started at the predicted appearance time of contrast material in the pulmonary trunk based on a previous dynamic scan using a test bolus injected with the same injection rate as a main bolus. CTPA using protocol A showed the optimal opacification of the pulmonary artery with pulmonary venous contamination. Proper CTPA images in the absence of venous contamination were obtained in protocol B. CTPA with a scan duration for 8 s should be started at the appearance time of contrast enhancement in the pulmonary trunk, which can be identified exactly when a test bolus is injected at the same injection rate used for the main bolus.

• 한국전자파학회논문지
• /
• 제29권9호
• /
• pp.668-676
• /
• 2018

위성통신에서는 낮은 PAPR(Peak-to-Average Power Ratio), 높은 전송효율, 낮은 BER(Bit Error Rate)을 갖는 변조 기술이 요구되며, DAPSK(Differential Amplitude and Phase Shift Keying) 변조는 이러한 요구조건을 만족시킬 수 있는 기술로 평가되고 있다. 그러나 기존 DAPSK 변조는 정규적인 성좌도를 사용하기 때문에 성좌도의 안쪽 동심원에 존재하는 심볼들의 유클리디안(Euclidean) 거리가 매우 가까워서 높은 성능을 내기에 적합하지 않다. 본 논문에서는 기존 DAPSK 시스템의 성능을 개선하기 위하여 대조표 기반의 효율적인 성좌도 배치법을 사용하는 DAPSK 시스템을 제안하고 성능을 평가한다. 시뮬레이션 결과, 기존 16-DAPSK 시스템과 비교하여 효율적인 성좌도 배치법을 사용하는 16-DAPSK 시스템은 수신 심볼 검출기에 사용되는 심볼의 수 K가 2일 때, $10^{-4}$의 BER 성능을 만족시키기 위한 SNR(Signal-to-Noise Ratio)을 약 0.8 dB 개선할 수 있음을 확인하였다.

• KSBB Journal
• /
• 제14권3호
• /
• pp.384-388
• /
• 1999

단위진동전류 검출기를 정착한 고성능 액체 크로마토그래프를 이용하여 생체내에 저동도로 존재하며 항생제 및 면역억제제로 그 사용이 주목받고 있는 glucose-1-phosphate (G-1-P)를 분리, 분석하였다. 기존의 본석방법인 세 가지 효소의 혼합사용을 이용한 자외선분석법과 선형성 (2 - $20{\mu}M$ 범위에서 기울기는 $4.8{\times}10^4$ 피크면적/${\mu}M$)과 재현성을 비교한 결과 본 분석법이 더 효율적임을 알 수 있었다. 최저 측정한계는 $2{\mu}M$이었다. 실재 내열성 효소반응액을 이용한 분석에서 G-1-P 및 부산물인 glucose-G-phosphate도 분리되었다. 본 분석방법은 생체내에 존재하는 여러 형태의 탄수화물 이성질체의 분리를 가능케 해, 생체내 탄수화물 대사연구에 효율적으로 이용될 수 있다.

• Biomolecules & Therapeutics
• /
• 제15권3호
• /
• pp.187-191
• /
• 2007

This study was conducted to compare the bioavailability of two brands of atenolol (50 mg) tablets, which are a generic product of $Ditent^{\circledR}$ (Daewon Pharmaceutical Co., Ltd., Korea) and an innovator product $Tenormin^{\circledR}$ (Hyundai Pharm. Ind. Co., Ltd., Korea), in 20 healthy Korean male volunteers. The volunteers received a single 50 mg dose of each atenolol formulation according to a randomized, two-way cross-over design. The washout period between treatments was 1 week. Plasma samples were obtained over a 24-hour interval, and atenolol concentrations were determined by HPLC with a fluorescence detector. From the plasma atenolol concentration vs. time curves, the following parameters were compared: area under the plasma concentration-time curve ($AUC_{0-24}$), peak plasma concentration ($C_{max}$), time to reach peak plasma concentration ($T_{max}$), and terminal first order elimination half-life ($t_{1/2}$). No statistically significant difference was obtained between the $T_{max}$ values, and the logarithmic transformed $AUC_{0-24}$ and $C_{max}$ values of the two products. The 90% confidence interval for the ratio of the logarithmically transformed AUC and $C_{max}$ values of $Ditent^{\circledR}$ over those of $Tenormin^{\circledR}$ were calculated to be between 0.85 and 1.04, and 0.89 and 1.07, respectively; both were within the bioequivalence limit of 0.80-1.25. The mean of $T_{max}$ in $Tenormin^{\circledR}$ group was 3.1 hour, and that in Ditent$^{\circledR}$ group was 3.2 hour. The values of $t_{1/2}$ between the two products were found comparable, and the mean values were 5.2 hour in the both products. Based on these results, it was concluded that $Ditent^{\circledR}$ was comparable to $Tenormin^{\circledR}$ in both the rate and extent of absorption, indicating that $Ditent^{\circledR}$ was bioequivalent to the reference product, $Tenormin^{\circledR}$.

• JSTS:Journal of Semiconductor Technology and Science
• /
• 제16권4호
• /
• pp.425-435
• /
• 2016

This paper describes a spread-spectrum clock generation method by utilizing a ${\Delta}{\Sigma}$ digital PLL (DPLL) which is solely based on binary phase detection and does not require a linear time-to-digital converter (TDC) or other linear digital-to-time converter (DTC) circuitry. A 1-bit high-order ${\Delta}{\Sigma}$ modulator and a hybrid finite-impulse response (FIR) filter are employed to mitigate the phase-folding problem caused by the nonlinearity of the bang-bang phase detector (BBPD). The ${\Delta}{\Sigma}$ DPLL employs a two-point modulation technique to further enhance linearity at the turning point of a triangular modulation profile. We also show that the two-point modulation is useful for the BBPLL to improve the spread-spectrum performance by suppressing the frequency deviation at the input of the BBPD, thus reducing the peak phase deviation. Based on the proposed architecture, a 3.2 GHz spread-spectrum clock generator (SSCG) is implemented in 65 nm CMOS. Experimental results show that the proposed SSCG achieves peak power reductions of 18.5 dB and 11 dB with 10 kHz and 100 kHz resolution bandwidths respectively, consuming 6.34 mW from a 1 V supply.

• 천문학논총
• /
• 제11권1호
• /
• pp.109-123
• /
• 1996

We have developed a 5GHz continuum receiver system. The receiver is a direct type receiver. In order to reduce the noise due to the fluctuation of the gain in the amplifiers, the system employs the Dicke switching method. We made the 5GHz low-noise amplifier and the bandpass filter. The low-noise amplifier gives ${\sim}35dB$ gain and has ${\sim}210K$ noise temperature. The bandpass filter has a passband between 4.3 and 5.4GHz. We also made switch driver, video amplifiers, phase detector, and integrator. Using a 1.8 meter offset parabolic antenna, we measured the efficiency of the system. Since the antenna does not have a driver to track objects, observations were performed with the antenna fixed. The measured noise temperature of the system is ${\sim}650K$. From the observation of the blank sky, noise level was measured. It was found that the systematic noise(${\sim}0.5K$: peak to peak value) is much larger than the thermal noise. The systematic noise is possibly related to the stability of the DC power supplied to the receiver system. Besides the noise of the system, it was found that the airplanes are the very serious noise sources. We measured the radio flux of the Sun using the developed system. The observed radio flux of the Sun is ${\sim}10^6Jy$, which is close to the known value of the quiet Sun. The test observation of the Sun shows that the angular beam size of the antenna is ${\sim}2.2^{\circ}$.

• 한국군사과학기술학회지
• /
• 제17권1호
• /
• pp.90-95
• /
• 2014

The system design and the system performance analysis of 3D imaging laser radar system for the mapping purpose is addressed in this article. For the mapping, a push-bloom scanning method is utilized. The pulsed fiber laser with high pulse energy and high pulse repetition rate is used for the light source of laser radar system. The high sensitive linear mode InGaAs avalanche photo-diode is used for the laser receiver module. The time-of-flight of laser pulse from the laser to the receiver is calculated by using high speed FPGA based signal processing board. To reduce the walk error of laser pulse regardless of the intensity differences between pulses, the time of flight is measured from peak to peak of laser pulses. To get 3D image with a single pixel detector, Risley scanner which stirs the laser beam in an ellipsoidal pattern is used. The system laser energy budget characteristics is modeled using LADAR equation, from which the system performances such as the pulse detection probability, false alarm and etc. are analyzed and predicted. The test results of the system performances are acquired and compared with the predicted system performance. According to test results, all the system requirements are satisfied. The 3D image which was acquired by using the laser radar system is also presented in this article.