• Maxillofacial Plastic and Reconstructive Surgery
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• 제37권
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• pp.27.1-27.7
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• 2015

The aim of this study was to evaluate the clinical relevance of autogenous fresh demineralized tooth (Auto-FDT) prepared at chairside immediately after extraction for socket preservation. Teeth were processed to graft materials in block, chip, or powder types immediately after extraction. Extraction sockets were filled with these materials and dental implants were installed immediately or after a delay. A panoramic radiograph and a conebeam CT were taken. In two cases, tissue samples were taken for histologic examination. Vertical and horizontal maintenance of alveolar sockets showed some variance depending on the Auto-FDT and barrier membrane types used. Radiographs showed good bony healing. Histologic sections showed that it guided good new bone formation and resorption pattern of the Auto-FDT. This case series shows that Auto-FDT prepared at chairside could be a good material for the preservation of extraction sockets. This study will suggest the possibility of recycling autogenous tooth after immediate extraction.

• 센서학회지
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• 제25권5호
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• pp.349-353
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• 2016

Recently, research on bolometer-type uncooled infrared image sensor which is made for industrial applications has been increasing. In general, it is difficult to calibrate fixed pattern noise (FPN) of bolometer array. In this paper, average-current calibration algorithm is presented for reducing bolometer resistance offset. A resistor which is produced by standard CMOS process, on the average, has a deviation. We compensate for deviation of each resistor using average-current calibration algorithm. The proposed algorithm has been implemented by a chip which is consisted of a bolometer pixel array, average current generators, current-to-voltage converters (IVCs), a digital-to-analog converter (DAC), and analog-to-digital converters (ADCs). These bolometer-resistor array and readout circuit were designed and manufactured by $0.35{\mu}m$ standard CMOS process.

• 한국지능시스템학회논문지
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• 제11권8호
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• pp.764-770
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• 2001

본 논문에서는 대용량의 퍼지 데이터를 고속으로 전송 및 추론하기 위해 새로운 PCI 버스 기반 병렬 퍼지 시스템을 제안한다. 많은 퍼지 데이터의 고속전송을 위해 PCI 9050 인터페이스를 사용하고, 병렬 퍼지 추론 시스템을 위한 병렬 퍼지 모듈들을 FPGA로 설계하여 PCI 타겟 코어로서 병렬로 동작하게 한다. 여기서 소속함수들의 각 요소와 전건부 또는 후건부부분의 병렬화을 고려하여 제안된 시스템을 VHDL을 사용하여 설계 및 구현하였다. 제안된 시스템은 실시간에 고속의 퍼지추론을 요하는 시스템 또는 대용량 인공위성 영상 데이터의 패턴 인식 등과 같이 다수의 전건부, 후건부의 변수를 갖는 시스템에 활용될 수 있다.

• 대한전기학회논문지:전기물성ㆍ응용부문C
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• 제54권8호
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• pp.378-383
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• 2005

We report the development of miniature fluorescence detection systems that employ miniature prism, mirrors and low coat CCD camera to detect the fluorescence emitted from 40 fluorescently-labeled protein patterns without scanner. This kind of miniature fluorescence detection system can be used in point of care. We introduce two systems, one uses prism+mirror block and the other uses prism and two mirrors. A large NA microscope eyepiece and low cost CCD camera are used. We fabricated protein chip containing multi-pattern BSA labeled with Cy5, using MEMS technology and modified the surface chemically to clean and to immobilize proteins. The measurements show that the combination of prism and mirrors can homogenize elliptical excitation light over the sample with higher optical efficiency, and increase the separation between excitation and fluorescence light at the CCD to give higher signal intensity and higher signal to noise ratio. The measurements also show that protein concentrations ranging from 10 ng/ml to 1000 ng/ml can be assayed with very small error. We believe that the proposed fluorescence detection system can be refined to build a commercially valuable hand-held or miniature detection device.

• 마이크로전자및패키징학회지
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• 제9권4호
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• pp.61-68
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• 2002

지금까지 전자 디바이스의 솔더접합부에 대한 신뢰성 평가에 있어서는 열충격시험에 의한 평가가 주류를 이루었다. 그러나 최근 모바일 제품이 소형화/다기능화되고 고밀도실장에 대한 요구가 증가함에 따라 BGA/CSP와 같은 솔더볼을 사용하는 패키지가 표면실장의 주류를 이루게 되었으며, 솔더접합부에 대한 메커니컬 스트레스 수명이 요구되어지고 있다. BGA/CSP의 솔더접합부에 대한 신뢰성 평가는 하중을 가한 상태에서 데이지체인 패턴의 전기적 저항변화와 스트레인 게이지에 의한 스트레스-스트레인 커브에 의해 행해진다. 본 연구에서는 자체 개발한 PCB만능시험장치의 응용과 솔더접합부에 대한 메커니컬 스트레스의 동적거동을 평가한 소니의 실험자료를 소개하도록 한다.

• 센서학회지
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• 제22권5호
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• pp.352-356
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• 2013

We developed a novel fabrication method of polydimethylsioxane (PDMS) lens, which can easily control the shapes of the lens using soft lithography with common photolithography and water droplet molding. A mold for PDMS lens was prepared by patterning of hydrophobic photoresist on the hydrophilic substrate and dispensing small water droplets onto the predefined hydrophilic patterns. The size of patterns determined the dimension of the lens and the dispensed volume of the water droplet decided the radius of curvature of the PDMS lens independently. The water droplet with photoresist pattern played a robustly fixed mold for lens due to difference in wettability. The radius of curvature could be calculated theoretically because the water droplets could approximate spherical cap on the substrate. Finally, concave and convex PDMS lenses which could reduce or magnify optically were fabricated by curing of PDMS on the prepared mold. The measured radii of the fabricated PDMS lenses were well matched with the estimated values. We believe that our simple and efficient fabrication method can be adopted to PDMS microlens and extended to micro optical device, lab on a chip, and sensor technology.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1996년도 춘계학술대회
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• pp.260-265
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• 1996

The purpose of this study was to implemented a general purpose programmable nerve stimulator system as a research tool for studying psychophysiological performance associated with various stimulation waveform. This system is composed of hardware and software, the former are the personal computer(180586) and control unit(one-chip microprocessor, D/A converter, digital output), the latter are programmed in VISUAL BASIC and ASSEMBLY Which are programmed for the programmable nerve stimuli pattern editor and communication interface, waveform preprocessing, and stimuli generator. The control unit which is entrolled by the personal computer is capable of delivering the programmable nerve stimuli waveform. This system has research potential for determining the effect of various neuromuscular blockade in alternated physiological stat is.

• 대한안전경영과학회지
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• 제17권3호
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• pp.355-362
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• 2015

There has been an increase of using Bosch Process to fabricate MEMS Device, TSV, Power chip for straight etching profile. Essentially, the interest of TSV technology is rapidly floated, accordingly the demand of Bosch Process is able to hold the prominent position for straight etching of Si or another wafers. Recently, the process to prevent under etching or over etching using EPD equipment is widely used for improvement of mechanical, electrical properties of devices. As an EPD device, the OES is widely used to find accurate end point of etching. However, it is difficult to maintain the light source from view port of chamber because of contamination caused by ion conflict and byproducts in the chamber. In this study, we adapted the SPOES to avoid lose of signal and detect less open ratio under 1 %. We use 12inch Si wafer and execute the through etching 500um of thickness. Furthermore, to get the clear EPD data, we developed an algorithm to only receive the etching part without deposition part. The results showed possible to find End Point of under 1 % of open ratio etching process.

• 대한한의학방제학회지
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• 제29권4호
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• pp.267-275
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• 2021

Objectives : Previously, we reported that compound K isolated from fermented ginseng by Aspillus oryzae has a wide biochemical and pharmacological effect, including anti-cancer activity in prostate cancer PC-3 cells. Despite these findings, its signaling pathway and gene expression pattern are not clearly understood. Methods : To confirm the gene expression study of treated with compound K in PC-3 cells, a cDNA microarray chip composed of 44K human cDNA probes was used. MTT assay, western blot analysis, propidium iodide staining, and annexin V/propidium iodide staining were analyzed. Results : We confirmed the differences of gene expression profiles. Then, we analyzed with the cell cycle arrest, cell death and cell proliferation related genes using DAVID database. Conclusions : Our finding should be useful for understanding genome-wide expression patterns of compound K-mediated cell cycle arrest toward induction of cell death and be helpful for finding future cancer therapeutic targets for prostate cancer cells.

• 한국기계가공학회지
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• 제17권6호
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• pp.1-6
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• 2018

Recently nano meter size pattern (sub-micro scale) can be machined mechanically using a diamond tool. Many studies have found a 'size effect' which referred to a specific cutting energy increase with the decrease in the uncut chip thickness at micro scale machining. A new analysis method was suggested in order to observe 'size effect' in nano scale machining and to verify the cause of the 'size effect' in this study. The diamond tool was indented to a vertical depth of 1,000nm depth in order to simplify the stress state and the normal force was measured continuously. The tip rounding was measured quantitatively by AFM. Based on the measurements and theoretical analysis, it was verified that the main cause of the 'size effect' in nano scale machining is geometrically necessary dislocations, one of the intrinsic material characteristics. st before tool failure.