• Transactions of the Korean Society of Mechanical Engineers
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• v.16 no.8
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• pp.1503-1512
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• 1992

The strength evaluation and life prediction on the corrosion part of structure is one of the most important subjects, as a viewpoint of reducing economic loss by regular inspection, maintenance, repair and replace. For this purpose, it has been difficult to obtain the available data on growth of pit depth or growth rate of each pit which depends on time. In this paper, the life prediction and strength evaluation method was suggested for the structure with irregular stress concentration part by surface corrosion. The statistical distribution pattern of corrosion depth and the degree of fatigue strength decline were confirmed according to corrosion period by artificial corrosion of SS41 steel. The life prediction and the fatigue strength evaluation of materials with consideration of the corrosion period on the extreme value statistic analysis by the data of maximum depth of corrosion and on random variable was studied.

• Transactions of the Korean Society of Machine Tool Engineers
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• v.15 no.6
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• pp.58-63
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• 2006

FIB equipment can perform sputtering and chemical vapor deposition simultaneously. It is very advantageously used to fabricate a micro structure part having 3D shape because the minimum beam size of ${\Phi}10nm$ and smaller is available. Since general FIB uses very short wavelength and extremely high energy, it can directly make a micro structure less than $1{\mu}m$. As a result, FIB has been probability in manufacturing high performance micro devices and high precision micro structures. Until now, FIB has been commonly used as a very powerful tool in the semiconductor industry. It is mainly used for mask repair, device correction, failure analysis, IC error correction, etc. In this paper FIB-Sputtering and FIB-CVD characteristic analysis were carried out according to $Ga^+$ ion beam current that is very important parameter for minimizing the pattern size and maximizing the yield. Also, for FIB-Sputtering burr caused by redeposition of the substrate characteristic analysis was carried out.

• Journal of the Korean Society for Advanced Composite Structures
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• v.4 no.1
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• pp.40-46
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• 2013

This paper presents the design, fabrication and performance of a reinforced concrete beam strengthened by GFRP box plate and its possibility for structural rehabilitations. The load capacity, ductility and failure mode of reinforced concrete structures strengthened by FRP box plate were investigated and compared with traditional FRP plate strengthening method. This is intended to assess the feasibility of using FRP box plate for repair and strengthening of damaged RC beams. A series of four-point bending tests were conducted on RC beams with or without strengthening FRP systems the influence of concrete cover thickness on the performance of overall stiffness of the structure. The parameters obtained by the experimental studies were the stiffness, strength, crack width and pattern, failure mode, respectively. The test yielded complete load-deflection curves from which the increase in load capacity and the failure mode was evaluated.

• Journal of the Korea institute for structural maintenance and inspection
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• v.9 no.1
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• pp.243-250
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• 2005

In elevated irrigation aquaducts, one can observe a common damage pattern. That is, cracks, and crushing of concrete are usually repeated at a certain interval even if no faults are found in the design and construction of the structures. To investigate the causes of this damage, longitudinal deformations of several aquaducts have been measured. The analysis of the measured data suggests that the damages are mainly caused by cumulative repetition of extension and contraction due to temperature changes.

• Proceedings of the Korea Concrete Institute Conference
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• 2008.04a
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• pp.165-168
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• 2008

This paper presents the design, fabrication and performance of a reinforced concrete beam strengthened by GFRP box plate and its possibility for structural rehabilitations. The load capacity, ductility and failure mode of reinforced concrete structures strengthened by FRP box plate were investigated and compared with traditional FRP plate strengthening method. This is intended to assess the feasibility of using FRP box plate for repair and strengthening of damaged RC beams. A series of four-point bending tests were conducted on RC beams with or without strengthening FRP systems the influence of concrete cover thickness on the performance of overall stiffness of the structure. The parameters obtained by the experimental studies were the stiffness, strength, crack width and pattern, failure mode, respectively. The test yielded complete load-deflection curves from which the increase in load capacity and the failure mode was evaluated.

• International Journal of Oral Biology
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• v.36 no.4
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• pp.167-172
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• 2011

LAR-RPTP (leukocyte common antigen-related receptor protein tyrosine phosphatase) is an important regulator in the nervous system, but little is known about its expression pattern in rat trigeminal ganglion (TG) neurons. To examine whether LAR-RPTP is expressed in the TG in the current study, we sacrificed rats at 0, 7, 10 and 56 day postpartum (dpp) and a second group of rats at 3 and 5 days after an experimental tooth extraction as a TG injury model. RT-PCR was then used to determine the level of LAR-RPTP expression in the TG and immunohistology was employed to detect the subcellular localization of the protein. The mRNA expression of LAR-RPTP during the developmental stages in the TG was found to gradually increase. After experimental tooth extraction however, these transcript levels had significantly decreased at three days. LAR-RPTP protein signals in the TG were found to be cytoplasmic in the normal animals but interestingly, at five days after an experimental tooth extraction, these signals were rare. These results indicate that LAR-RPTP may be regulated during both the developmental as well as regenerative processes that take place in the TG. This further suggests that LAR-RPTP is not only involved in primary axonogenesis but possibly also in the molecular control of axons during TG repair.

• Computers and Concrete
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• v.16 no.2
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• pp.245-260
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• 2015

In this study, nominal moment-axial load interaction diagrams, moment-curvature relationships, and ductility of rectangular hybrid beam-column concrete sections are analyzed using the modified Hognestad concrete model. The hybrid columns are primarily reinforced with steel bars with additional Glass Fiber Reinforced Polymer (GFRP) control bars. Parameters investigated include amount, pattern, location, and material properties of concrete, steel, and GFRP. The study was implemented using a user defined comprehensive $MATLAB^{(R)}$ simulation model to find an efficient hybrid section design maximizing strength and ductility. Generating lower bond stresses than steel bars at the concrete interface, auxiliary GFRP bars minimize damage in the concrete core of beam-column sections. Their usage prevents excessive yielding of the core longitudinal bars during frequent moderate cyclic deformations, which leads to significant damage in the foundations of bridges or beam-column spliced sections where repair is difficult and expensive. Analytical results from this study shows that hybrid steel-GFRP composite concrete sections where GFRP is used as auxiliary bars show adequate ductility with a significant increase in strength. Results also compare different design parameters reaching a number of design recommendations for the proposed hybrid section.

• Journal of the Korea Society of Computer and Information
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• v.24 no.3
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• pp.135-141
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• 2019

The purpose of this study was to analyze the direct measurement data of 20-25 years male university students of 7th Size Korea data and to characterize and to type the body shape of lower body. It was to provide basic data for male university students' pants pattern production. The lower body part consisted of the 'horizontal factor' of the lower body composed of circumference, thickness, width, and 'vertical factor' of the lower body composed of the length and height. This was consistent with the analysis of the body shape factor of the lower half of male adolescents. The lower body shape was classified into four types. Type 1 was thick and relatively long in the lower body and was named 'thick long leg'. Type 2 was named 'short bird legs' because the lower body was thin and relatively short. Type 3 was relatively thin and long, so the lower body was named 'long crane leg'. In Type 4, the lower body was relatively thick and short, which means 'short pillar leg'. In the case of 20-25 year-old male university students, they have different body shapes depending on the girth and length of the lower half of their body as they have reached adulthood. Therefore, it would be necessary to provide a sales system that allows the repair of the length of the pants to be facilitated, and the length of the pants to be repaired when the pants are selected according to the circumference. Future studies will need to classify the body shape according to angle and flatness.

• International journal of advanced smart convergence
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• v.8 no.1
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• pp.184-195
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• 2019

This study investigates the hair restoration efficacy of selected radish saponin extracts on nude mice. Nude mice genetically predisposed to pattern balding were used in this study. Our study revealed the underlying mechanism of stimulating hair growth in athymic nude mice by repair the nu/nu follicular keratin differentiation defect. Thus, the topical application of radish saponin may represent a novel strategy for the management and therapy of certain forms of alopecia. The term of hair density of PEE treated nude mice were significantly increase as compared with of control nude mice. Histological observation of skin sample showed no hair follicle or only distorted hair follicles were observed in the control samples, in contrast, by the PEE treatment groups showed a fully formed and increased the number of hair follicles up to three times higher than that of control group in terms of the number of hair follicles in nude mouse skin.PEE treated mice the number of BrdU-labeled keratinocytes per anagen follicle increased significantly, especially in the follicular bulbs and outer root sheath compared with the control mice. Moreover, PEE-treated nude mice also exhibited a significant increase in the number of BrdU-labeled epidermal keratinocyte proliferation.

• Molecules and Cells
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• v.42 no.1
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• pp.1-7
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• 2019

Macrophage is an important innate immune cell that not only initiates inflammatory responses, but also functions in tissue repair and anti-inflammatory responses. Regulating macrophage activity is thus critical to maintain immune homeostasis. Tyro3, Axl, and Mer are integral membrane proteins that constitute TAM family of receptor tyrosine kinases (RTKs). Growing evidence indicates that TAM family receptors play an important role in anti-inflammatory responses through modulating the function of macrophages. First, macrophages can recognize apoptotic bodies through interaction between TAM family receptors expressed on macrophages and their ligands attached to apoptotic bodies. Without TAM signaling, macrophages cannot clear up apoptotic cells, leading to broad inflammation due to over-activation of immune cells. Second, TAM signaling can prevent chronic activation of macrophages by attenuating inflammatory pathways through particular pattern recognition receptors and cytokine receptors. Third, TAM signaling can induce autophagy which is an important mechanism to inhibit NLRP3 inflammasome activation in macrophages. Fourth, TAM signaling can inhibit polarization of M1 macrophages. In this review, we will focus on mechanisms involved in how TAM family of RTKs can modulate function of macrophage associated with anti-inflammatory responses described above. We will also discuss several human diseases related to TAM signaling and potential therapeutic strategies of targeting TAM signaling.