• 대한간호학회지
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• 제34권6호
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• pp.1081-1091
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• 2004

Purpose: This study was done to identify the risk factors associated with falls among patients with Parkinson's Disease(PD). Method: A retrospective study design was used through the collection of physiological and physical health, and psychosocial functions. Results: Of the 100 participants, fifty-nine(59%) reported one or more falls and seventy-one(71%) reported one or more near-falls. Anaverage 34.7 falls and 150.3 near-falls were reported in the previous year per person. Stage of PD, foot problems, balance, fear of falling, and activities of daily living were significantly associated with an increased risk of falls. Conclusion: The findings confirm the high risk of falling in PD patients. Also these results have implications for developing fall prevention programs for PD patients.

• 대한자기공명의과학회:학술대회논문집
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• 대한자기공명의과학회 2003년도 제8차 학술대회 초록집
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• pp.88-88
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• 2003

Purpose： To investigate whether there are significant changes in regional brain metabolism in patients with Parkinson's disease after thalamotomy using proton magnetic resonance spectroscopy (1H MRS). Materials and methods： Fifteen patients with Parkinson's disease of mean age 56.5 years (7 males and 8 females； mean age, 56.5 years) that have treated with levodopa were included. All patients with tremor experienced amelioration of their symptoms on the side contralateral to the thalamotomy. As a single-voxel technique, 1H MR spectra were obtained from the volume of interested regions in thalamus and primary motor cortex. Spectral parameters were： 20 ms TE, 2000 ms TR, 128 averages, 2500 Hz spectral width, and 2048 data points.

• 한국운동역학회지
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• 제30권1호
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• pp.83-91
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• 2020

Objective: The study aimed to develop a functional performance index that evaluates the functional performance of Parkinson's patients, i.e., to integrate biomechanical measurements of walking, balance, muscle strength and tremor, and to use multiple linear regression with stepwise methods to identify the most suitable predictors for the progression of disease. Method: A total of 60 subjects were tested for sub-variables of four factors: walking, balance, isometric strength and hand tremors. Potential independet variables were extracted through correlation analysis of the sub-variables and dependent variables, Hoehn & Yahr scale. And then, a stepwise multiple regression analysis using the potential independent variables was performed to identify predictor of Hoehn & Yahr scale. Results: First, the results of the study showed that physical composition and gait had a relatively more correlated with the progression of the disease, compared to balance and hand tremor. Second, Parkinson's functional performance is characterized by dynamic pattern of walking, such as foot clearance and turning angle (TA) of walking, and a high-explained regression model is completed. Conclusion: The study emphasized the importance of walking variables and body composition in minor pathological features compared to Parkinson's patient's balancing ability and hand tremor. Specifically, it revealed that dynamic walking patterns functionally characterize patients. The results are worth considering when assessing functional performance related to the progression of the disease at the site.

• 대한간호학회지
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• 제39권1호
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• pp.116-123
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• 2009

Purpose: The study was done to identify lower urinary tract symptoms (LUTS) and to evaluate the factors affecting LUTS for the people with Parkinson's disease. Methods: The research design was a cross-sectional study with interviews using a structured questionnaire. The participants were 72 patients with Parkinson's disease who were seen in the Neurology clinic of a university hospital from September to November 2005. Results: Mean score of LUTS for the participants was 10.11. In each symptom score of LUTS (range 0-5), weak stream was the highest 2.06, followed by nocturia 1.71, and urgency 1.61. The severity of LUTS was moderate to severe group for 51%. LUTS were significantly different by regular exercise. Positive correlations were observed between Hoehn and Yahr stage (stage of disease severity) and frequencyand between Hoehn and Yahr stage and urgency (r=.280, p=.018; r=.328, p=.005). LUTS were significantly predicted by regular exercise (p=.001) which explained 15.0% of the variance in LUTS. Conclusion: Regular exercise was found to be a very important factor associated with LUTS for patients with Parkinson's disease.

• 대한통합의학회지
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• 제4권2호
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• pp.1-11
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• 2016

Purpose : The purpose of this study was to identify whether virtual reality-based exercise could improve on balance, gait and fall efficacy in patients with Parkinson's disease. Methods : Ten patients with Parkinson's disease were randomly divided into either an experimental or control group. The experimental subjects performed vertual reality-based exercise, whereas the control subjects performed conventional physical therapy for 4 weeks. The balance, gait and fall efficacy of all subjects were assessed by using the Measurement Training and Documentation (MTD) balance system, force platform system, Korean version of Berg Balance scale (K-BBS), 6 Minute Walk Test (6MWT), and Korean version of Fall efficacy scale (K-FES) at pre training and post training. Wilcoxon signed rank test was used to analyze change before and after intervention in intra-group. Mann Whitney U test was used to analyze changes of all variables in inter-groups. Results : Subjects in the experimental group showed significant improvements in difference of weight distribution, K-BBS scores, antero-posterior and medio-lateral sway length, ground reaction force (GRF), 6MWT, and step length following training. The changes of difference of weight distribution, K-BBS scores, AP Sway Length, GRF, 6MWT, step length and K-FES scores in the experimental group were significantly more than them of the control group. Conclusion : The result of this study suggest that virtual reality-based exercise training is an intervention to improve on balance, gait, and falls efficacy in patients with Parkinson's disease.

• 대한한의학회지
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• 제24권3호
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• pp.172-183
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• 2003

Objective : This study was designed to determine whether manual acupuncture therapy is effective for symptoms of patients with idiopathic Parkinson's disease. Methods : Nineteen patients consecutively enrolled in this study. The subjects were divided into two groups : the first group (n=12) discontinued antiparkinsonian drug treatment, the second group (n=7) continued antiparkinsonian drug treatment Acupuncture therapy was performed twice a week for 8 weeks. In the first group, the acupuncture was performed after 2 weeks of drug wash-out period. The patient's symptoms were assessed at pre-treatment, 4 weeks and 8 weeks after the acupuncture by unified Parkinson's disease rating scale (UPDRS), modified Hoehn-Yahr (H-Y) stage, Schwab & England activity of daily living and Freezing of Gait Questionnaire(FOGQ). Results : In the first group that discontinued. antiparkinsonian drug treatment, the total UPDRS scores were significantly improved after 4 weeks (p=0.0l4) and after 8 weeks (p=0.049) compared to the pre-treatment. Particularly, the scores of UPDRS III were significantly improved after 8 weeks (p=0.032). In the second group that continued antiparkinsonian drug treatment, the total UPDRS scores were significantly improved after 4 weeks (p=0.027) and after 8 weeks (p=0.018). Particularly, the scores of UPDRS II were significantly improved after 4 weeks (p=0.042) and after 8 weeks (p=0.043), and UPDRS IV were significantly improved after 8 weeks (p=0.043). The scores of ADL were significantly improved after 8 weeks (p=0.046). Conclusion : This study suggests that manual acupuncture therapy is effective for the improvement of certain symptoms in patients with idiopathic Parkinson's disease.

• Journal of Korean Neurosurgical Society
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• 제59권6호
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• pp.655-658
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• 2016

Parkinson's disease (PD) patients frequently have several spinal deformities leading to postural instabilities including camptocormia, myopathy-induced postural deformity, Pisa syndrome, and progressive degeneration, all of which adversely affect daily life activities. To improve these postural deformities and relieve the related neurologic symptoms, patients often undergo spinal instrumentation surgery. Due to progressive degenerative changes related to PD itself and other complicating factors, patients and surgeons are faced with instrument failure-related complications, which can ultimately result in multiple revision surgeries yielding various postoperative complications and morbidities. Here, we report a representative case of a 70-year-old PD patient with flat back syndrome who had undergone several revision surgeries, including anterior and posterior decompression and fusion for a lumbosacral spinal deformity. The patient ultimately benefitted from a relatively short segment fixation and corrective fusion surgery.

• 음성과학
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• 제10권4호
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• pp.221-227
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• 2003

Diadochokinetic (DDK) speech task has been utilized as an evaluating tool for speakers with dysarthria for many years. This study attempted to differently diagnose multiple system atrophy (MSA) from idiopathic Parkinson's disease (PD) using patients' performance of DDK (i.e., alternate motion rate (AMR)). The subjects included 11 cases of pathologically confirmed MSA and 16 IPD patients who commonly presented with parkinsonian syndrome. The speech sample of each patient was analyzed acoustically using the MSPTM(Motor Speech Profile, a module of CSL). The results showed that the average DDK rate was significantly faster in the IPD than the MSA groups in all three syllables (i.e., /puh/, /tuh/. and /kuh/). We propose the average DDK rate variable as a core clinical trait in differentiating the two pathological conditions.

• Journal of Korean Medical Science
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• 제33권47호
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• pp.300.1-300.17
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• 2018

Parkinson's disease (PD) is the second most common neurodegenerative disorder. Although its major manifestation is motor symptoms, resulting from the loss of dopaminergic neurons in the substantia nigra, psychiatric symptoms, such as depression, anxiety, hallucination, delusion, apathy and anhedonia, impulsive and compulsive behaviors, and cognitive dysfunction, may also manifest in most patients with PD. Given that the quality of life - and the need for institutionalization - is so highly dependent on the psychiatric well-being of patients with PD, psychiatric symptoms are of high clinical significance. We reviewed the prevalence, risk factors, pathophysiology, and treatment of psychiatric symptoms to get a better understanding of PD for improved management.

• 동의신경정신과학회지
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• 제22권4호
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• pp.11-20
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• 2011

Objectives : The purpose of this study was to obtain some knowledge about the scalp acupuncture treatment on Parkinson's disease for the future practice and the research from the clinical studies in China. Methods : The literatures were searched using the database-China Academic Journals(CAJ) (2006-2011). Clinical studies of scalp acupuncture for Parkinson's disease-Randomized controlled trial(RCT), case control study, case series, case report- were included. Results : Of 65 articles, 12 Clinical studies met our inclusion criteria. Three case series reported a significant improvement in the patients with Parkinson's disease by scalp acupuncture, and 9 RCTs reported a significant effectiveness of scalp acupuncture as a monotherapy or as a combination therapy with Madopa Tablet(Levodopa + Benserazide HCl) treatment. Conclusions : The results of this study could be used for the future study about scalp acupuncture for Parkinson's disease.