• Asian Pacific Journal of Cancer Prevention
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• v.15 no.19
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• pp.8155-8159
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• 2014

Background: Breast cancer is the serious health concern in India causing the highest mortality rate in females, which occurs due to uncontrolled cell division and can be metastasize to other parts of the human body. Interactions with estrogen receptor (ER) alpha are mainly responsible for the malignant tumors with regulation of the transcription of various genes as a transcription factor. Most of the drugs currently used for the breast cancer treatment produce various side effects and hence we focused on natural compounds which do not exhibit any toxic effect against normal human cells. Materials and Methods: Structure of human ER was retrieved from the Protein Data Bank and the structures of flavonoid compounds have been collected from PubChem database. Molecular docking and drug likeness studies were performed for those natural compounds to evaluate and analyze the anti-breast cancer activity. Results: Finally two compounds satisfying the Lipinski's rule of five were reported. The two compounds also exhibited highest binding affinity with human ER greater than 10.5 Kcal/mol. Conclusions: The results of this study can be implemented in the drug designing pipeline.

• Journal of the Ergonomics Society of Korea
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• v.36 no.4
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• pp.325-341
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• 2017

Objective: The purpose of this study is to suggest the guidelines of operation phases to minimize injuries and musculoskeletal disorders in manual material handling (MMH) tasks through literature reviews. The guidelines are presented as the preparing phase, lifting phase, carrying phase, and lowering phase. Also, we summarized the non-numerical general guidelines for MMH tasks. Background: Manual material handling is still a main cause to musculoskeletal disorders. Method: Procedures of a literature review are classified into database selection, keyword search, title review, abstract review related to literature selection, guideline review and arrangement. A total 48 papers and books were analyzed in detail by title and abstract reviews. Results: In the preparing phase, we suggested the basic conditions in MMH, preparing procedure, clothing and protective equipment, and education. In the lifting and carrying phases, we recommended maximal acceptable weight by frequency and body posture. In the lowering phase, we suggested the lowest weight and safety body postures. Finally, we recommended general guidelines and guideline items for MMH. General guidelines are presented to suggest worker selection, technical education, and work design parts. Conclusion: We suggested the guidelines on the four operation phases of MMH tasks such as preparing, lifting, carrying, and lowering phases. Application: The findings of this study can be utilized as guidelines for proactive recommendations according to workers in MMH tasks.

• Journal of The Korean Association of Information Education
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• v.6 no.1
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• pp.53-63
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• 2002

The purpose of this thesis is to design and implement an efficient Web- based Project Learning System(WPLS) in particular for the interactive of an elementary school children. The WPLS in this paper has four main parts ; user interface, learner module, administrator module and database. This system was implemented in accordance with the project themes solving learning processes. So the learner module consists of five steps ; project theme proposal, project plan, project execution, web-publishing, and project test. WPLS can improve student`s ICT using ability and academic achievement.

• Proceedings of the Korean Institute of Intelligent Systems Conference
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• 2005.11a
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• pp.452-455
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• 2005

In order to reproduce the traffic accident, It must save the data automatically which traffic accident 30 seconds before using black box. The Black Box can detect traffic crash accidents automatically, and record the vehicle's motion and driver's maneuvers during a pre-defined time Belied before and after the accident. But it is not easy for the police to catch running away criminal. Because, criminal can remove proof if it is 2 hours or 3 hours at least. Therefore, in this paper, in order to catch a hit and run driver in the traffic accident road, it developed an structured Query Language Server and made parts database algorithm.

• Journal of Welding and Joining
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• v.14 no.6
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• pp.119-130
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• 1996

Welding is one of the important technologies in shipbuilding industry. Automation and productivity promotion of welding contribute to the cost saving of ship production. The quality and productivity of welding are dependent on the quality and suitability of technical information supplied by engineering parts. This paper describes the research results of welding information system for ship. The system can be used for the development of CIMS for shipbuilding. For this work, the welding information related to the ship Production were analyzed in detail. Object-oriented technique is applied to represent the complex and various welding information. To process the extend amount of the welding information of ship, database system was constructed. A pilot system for the bulk carrier ship was developed and can be used with ease by programming of event-driven method and implementaion of graphical user interlace.

• Journal of Multimedia Information System
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• v.7 no.2
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• pp.175-188
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• 2020

The paper focuses on conception and development of complex systems composed mainly by a pump syringe subsystem and an electronically injector that facilitates patients saving data operation for medical staff use. We successfully developed conventional approaches for medical system staff requirements, such as system boundary conditions. Decisions at a given level are studied. We propose a complex system architecture, based mainly on patients collected data and ordered stepper injection parameters. System is successfully simulated and prototyped. Design and implement tests are accomplished, the proposed system ensures both the electric syringe pump and the electric injector operation. In addition, this new system introduces several additional options as patient database development and automation injection operation. Development and software operating tests to create a visualization control interface are validated. The solution performs syringe function and electronic injector. User can manage a syringe in two C modes of technology. We propose a program composed of two linked parts. If an error such radiologist bad target selection is made, an image with lower intrinsic quality emerges. Developed Shoot syringe different electronic cards are simulated and prototyped, in addition, maps are driven, prototype. All tests results are accomplished.

• Journal of Korean Medical classics
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• v.30 no.4
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• pp.95-108
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• 2017

Objective : The current wuiwan poses a challenge in understanding related disease because one term refers to many different parts. Therefore, the objective of this paper is to review historical documents and define the areas of wuiwan revolving around the wuiwan-related disease. Method : The Sikuquanshu database, Traditional Chinese Medical(TCM) books webdatabase were studied, and selections were made from the texts that discussed wuiwan. Result & Conclusion : The term wuiwan is used to refer to stomach's capacity. The word wuiwan is first discovered in Neijing. wuiwan-related disease as shown in Neijing does not move beyond the scope of stomach. The view of seeing wuiwan as part of esophagus is discovered in the text which explains dysphagia, and it is believed that this expression was used in the purpose of pointing the airway and the esphagus. Therefore, the reason wuiwan was viwed as esophagus has to be confined within the texts in documents that explain dysphagia or within the Four-Constitution Medicine. Generally, it is more reasonable to see wuiwan within the scope of stomach.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.9 no.1
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• pp.47-58
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• 2005

Background and purpose: The purpose of this study is to review the recent 10 year Chinese achievements on the objectification of traditional pulse diagnosis in clinical area. Methods: From the China Journal Full Text Database (中國學術期刊全文數据庫) we searched papers on pulse diagnosis by the keyword 'Maizhen'(脈診) Resulls: The researches are summarized into four parts; (1) the researches on the normal pulse in the physiological state (2) the clinical researches of pulse diagnosis on the symptom and disease diagnosis (3) the clinical researches of pulse diagnosis on the acupuncture treatment (4) the application of pulse diagnosis on the functional evaluation of the athlete. Conclusion: The undoubted principles of the traditional pulse diagnosis are evaluated by the objective clinical researches. And the researchers are trying to find a new application area over the traditional one.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.21 no.11
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• pp.1796-1808
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• 1997

In order to perform leak-before-break design of nuclear piping systems and integrity evaluation of reactor vessels, full stress-strain curves and fracture resistance(J-R) curves are required. However it is time-consuming and expensive to obtain J-R curves experimentally. To resolve these problems, three different methods for predicting J-R curves from tensile data were proposed by the authors previously. The objective of this paper is to develop a computer program based on those J-R curve prediction methods. The program consists of two major parts ; the main program part for the J-R curve prediction and the database part. Several case studies were performed to verify the program, and it was shown that the predicted results were, in general, in good agreement with the experimental ones.

• Journal of the Korean Society of Industry Convergence
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• v.21 no.4
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• pp.183-189
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• 2018

The focus of this paper is to design and control a three fingered hand system with eight axes for smart factory with an flexible controller, and to keep a useful big database for dynamic manipulation based on the experimental results. The weight of the hand module is only 1.2 kg, but flexible motion and powerful grasping are possible. To achieve such a flexible motion control of a robotic hand, we have developed a robust and precise fingered hand with a control system incorporating image recognition system in which we deal with the problems of not only accuracy and range of motion but also the flexibility of hand. The fingers are arranged so as to grasp both circular and prismatic objects. In order to achieve the light mechanism, we reduced the number of joints and fingers as much as possible. In this study, it was used three fingers with eight axes which is the optimal number to achieve a robust grasping diverse shape parts for smart factory.