• Applied Microscopy
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• v.48 no.2
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• pp.33-42
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• 2018

Myosin X is one of myosin superfamily members having unique cellular functions on cytoskeletal reorganization. One of the most important cellular functions of myosin X is to facilitate the formation of membrane protrusions. Since membrane protrusions are important factors for diverse cellular motile processes including cell migration, cell invasion, path-finding of the cells, intercellular communications and so on, it has been thought that myosin X plays an important role in various processes that involve cytoskeletal reorganization including cancer progression and development of neuronal diseases. Recent studies have revealed that the unique cellular function of myosin X is closely correlated with its unique structural characteristics and motor properties. Moreover, it is found that the molecular and cellular activities of myosin X are controlled by its specific binding partner. Since recent studies have revealed the presence of various specific binding partners of myosin X, it is anticipated that the structural, biochemical and cell biological understanding of the binding partner dependent regulation of myosin X function can uncover the role of myosin X in diverse cell biological processes and diseases.

• Korea Trade Review
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• v.44 no.4
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• pp.1-17
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• 2019

The purpose of this paper is to suggest strategies for Korean companies to overcome the limitation of the international trade structure between Korea and Vietnam. This study examined foreign multinational distribution companies, Korean distribution companies and domestic distribution companies in Vietnam. A SWOT analysis conducted to propose effective strategies revealed that Saigon Mart, Vietnam's largest regional mart company, needs an O/W strategy and to capture market opportunities quickly through strategic alliances with foreign distribution companies, in order to gradually complement their core competencies internally. Lotte mart in Vietnam, one of Korea's three largest marts, needs to establish a T/S strategy in order to overcome the crisis situation in Vietnam market and succeed in business. BIG C Mart has over 40,000 diverse products needs to use a T/S strategy in order to effectively overcome the crisis situation in the Vietnamese market and to increase the possibility of business success. From the study findings and conclusions, various implications are derived. Vietnam is still very strong in socialism and regional characteristics, so it needs to build up close cooperation such as joint venture with local partners in the region and strategic alliances to increase the possibility of investment success.

• Journal of the Korea Safety Management & Science
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• v.24 no.3
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• pp.93-103
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• 2022

This study investigated the method of continuous improvement of small-medium company production processes through POSCO's QSS(Quick Six Sigma) activities. QSS is a field operation technique that encompasses the advantages of Six Sigma, TPS(Toyota Production System), TQM (Total Quality Management), and IE(Industrial Engineering). Through this, POSCO not only encourages activities centered on related small and medium-sized partners, etc., but is also expected to contribute to the continuous improvement of the company's own production process through QSS activities. In this study, rather than unconditionally carrying out activities according to the needs of large companies, the research is to help the continuous improvement of the actual production process of small and medium-sized enterprises by effectively applying and spreading QSS activities in consideration of the characteristics and environment of the company. For this purpose, empirical research is conducted on the process improvement activities and QSS activities of company Y, which has less than 100 assembly and production quality and inspection processes among SMEs. The changes in the production process improvement of SMEs through the application of the final QSS were investigated through empirical studies.

• Genomics & Informatics
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• v.21 no.2
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• pp.21.1-21.14
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• 2023

Fusobacterium nucleatum is a gram-negative bacteria associated with diverse infections like appendicitis and colorectal cancer. It mainly attacks the epithelial cells in the oral cavity and throat of the infected individual. It has a single circular genome of 2.7 Mb. Many proteins in F. nucleatum genome are listed as "Uncharacterized." Annotation of these proteins is crucial for obtaining new facts about the pathogen and deciphering the gene regulation, functions, and pathways along with discovery of novel target proteins. In the light of new genomic information, an armoury of bioinformatic tools were used for predicting the physicochemical parameters, domain and motif search, pattern search, and localization of the uncharacterized proteins. The programs such as receiver operating characteristics determine the efficacy of the databases that have been employed for prediction of different parameters at 83.6%. Functions were successfully assigned to 46 uncharacterized proteins which included enzymes, transporter proteins, membrane proteins, binding proteins, etc. Apart from the function prediction, the proteins were also subjected to string analysis to reveal the interacting partners. The annotated proteins were also put through homology-based structure prediction and modeling using Swiss PDB and Phyre2 servers. Two probable virulent factors were also identified which could be investigated further for potential drug-related studies. The assigning of functions to uncharacterized proteins has shown that some of these proteins are important for cell survival inside the host and can act as effective drug targets.

• Journal of the Korea Convergence Society
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• v.9 no.6
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• pp.287-298
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• 2018

This study, a second analysis research using raw data of the 6th Korea National Health and Nutrition Examination Survey(2013-015), places its purpose on examining risk factors for the mental health of the youth. With its target on 3,712 people in their twenties and thirties, it has used complex sample cross analysis to figure out the relationship between their mental health and eating habits. Also, it has carried out multiple logistic regression analysis for the purpose of grasping the youth's mental health risk factors. Under the circumstances, controlling the subjects' individual characteristics, the study has shown that males with their breakfast and dinner partners have lower possibilities of depression and suicidal thoughts. Meanwhile, in the case of females, their breakfast and lunch partners have played a key role in lowering their stress and suicidal thoughts. Given these results, the government will have to make all-out efforts to upgrade public places and spaces for the youth to eat together. All this will lead to their healthy eating habits and positive mental health. More specifically, it will have to create variable programs necessary for educating them to manage their diet and enjoy eating with other people.

• Information Systems Review
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• v.14 no.3
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• pp.115-129
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• 2012

A matchmaking system is a type of recommender systems that provides a set of dating partners suitable for the user by online. Many matchmaking systems, which are widely used these days, require users to specify their preferences with regards to ideal dating partners based on criteria such as age, job and salary. However, some users are not aware of their exact preferences, or are reluctant to reveal this information even if they do know. Also, users' selection standards are not fixed and can change according to circumstances. This paper suggests a new matchmaking system called Decision Tree based Matchmaking System (DTMS) that automatically adjusts the stated standards of a user by analyzing the characteristics of the people the user chose to contact. AMMS provides recommendations for new users on the basis of their explicit preferences. However, as a user's behavioral records are accumulated, it begins to analyze their hidden implicit preferences using a decision tree technique. Subsequently, DTMS reflects these implicit preferences in proportion to their predictive accuracy. The DTMS is regularly updated when a user's data size increases by a set amount. This paper suggests an architecture for the DTMS and presents the results of the implementation of a prototype.

• THE INTERNATIONAL COMMERCE & LAW REVIEW
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• v.38
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• pp.377-408
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• 2008

Globalization of R&D activities of multinational firms is becoming important in compared with the past, because of increasing globalization of world economy. So, every country tries to attract foreign investment including R&D activities. In this paper, effects of several factors, which determine the scale of foreign subsidiary's R&D activities in local market, are analyzed. Through the review of previous literature, I found that three groups of determinant factors. The first one is the factor which is related to characteristics of local market, such as competitive situation of local market, accessability to research institutions, etc. The second group is the factor which is related to relationship between foreign subsidiary and its mother company. The dominant factors of this group are operation strategy of foreign subsidiary, competitiveness of mother firm, and equity structure of foreign subsidiary. Finally the characteristics of industry affect to the scale of foreign subsidiary's R&D activities. Among these factors, 6 factors are chosen to investigate empirically. For the empirical investigation, 107 foreign subsidiaries among KOITA(Korea Industrial Technology Association)'s list are chosen. Each subsidiary has more than 50% of foreign equity and implement R&D activities in Korea. The results show that sales volume of foreign subsidiary is dominant influencing factor in determining scale of R&D activities in Korean market. And also I found that currently established firms are implementing more R&D activities than old established firms. This is quite interesting finding. However, R&D activities of foreign subsidiary are not vitalized in Korean market. It probably means that Korean government and Korean business partners have to make effort to enhance foreign firms/ R&D activities, because it could contribute technological and economic development of Korean market.

• The Journal of Information Systems
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• v.20 no.3
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• pp.161-186
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• 2011

To date, SCM research has mainly focused on the effects of controlled variables on SCM success and emphasized adoption strategies and critical success factors. Consequently, the effects of more uncontrolled variables such as partnership between SCM partners have been largely ignored. The purpose of this study, therefore, is to examine the effects of both controlled variables and uncontrolled variables on SCM performance through affecting RTE characteristics. The six factors examined in this study include Quality of information, partnership quality, Forecasting, Agility, Visibility, and SCM performance. In this study, SCM Performance was divided into three categories: Quality Performance, Cost Performance, Delivery Performance. All factors were examined from the perspective of part suppliers. The results of this study can be summarized as follows. First, SCM information quality positively affected SCM partnership quality, Forecasting, Agility, Visibility. Second, SCM partnership quality positively affected Forecasting, Agility. But, SCM partnership quality showed no significant effect on Visibility. Third, Forecasting had a significant impact on SCM performance. According to the detailed result of measuring SCM performance with Quality Performance, Cost Performance, Delivery Performance, although Forecasting affects Cost Performance, Delivery Performance directly, it does not affect Quality Performance directly. Fourth, Agility also had a significant impact on SCM performance. According to the detailed result of measuring SCM performance, Agility has significant impact on Quality Performance, Cost Performance, Delivery Performance. Fifth, Visibility, as expected, had a significant impact on SCM performance. According to the detailed result of measuring SCM performance, Visibility has significant impact on Quality Performance, Cost Performance, Delivery Performance.

• Journal of Families and Better Life
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• v.27 no.1
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• pp.17-29
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• 2009

The aim of this paper is to examine the demographic characteristics and the attitude about marriage and the policy of the unmarried male farmers. The contents of research are two folds: 1) Analyze the marriage related demographic statistics of rural area using the data from Korea Statistical Information System and marriage statistics in 2007, 2) survey analyses of the attitude toward marriage, perception and needs of international marriage, and related policies from data of 170 unmarried male farmers. The results are as follows: first, the marriage rates among over 15 years old of the rural area is 78.2% for men while 1.8% for 20${\sim}$24 age group and 9.3% for 25${\sim}$29 age group. The marriage rates in this area are varied by region especially low in Kyunggido & Jejudo. Second, the portion of international marriages of Korean male farmers with foreign partner are 11% among all international marriages of Korean males. There are high rates of male farmers' international marriage in Junranamdo and Kyungsangbukdo which are characterized by low level of urbanization, low inter-city mobility, low rates of age group of under 15 years and high portion of over age 65. Finally, the survey results showed that 83% of the sample lived with their parents; event though 80% of farmers think marriage is necessary, 60% had no plan of marriage because of difficulties to meet marriage partners and of lacking economic resources; they showed a negative perception toward the handicapped, foreigners, Afro-Americans, Westerners and divorcees as a marriage partner; they also showed negative recognition to international marriage because of observed problems of neighboring international marriage couples and concerns of cultural differences; they pointed out that the government's concern about improving quality of the environment of the rural area and reforming the international marriage aid law was the most necessary. The discussion and the future research directions were added.

• Structural Engineering and Mechanics
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• v.58 no.6
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• pp.1045-1075
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• 2016

Shallow footings are one of the most common types of foundations used to support mid-rise buildings in high risk seismic zones. Recent findings have revealed that the dynamic interaction between the soil, foundation, and the superstructure can influence the seismic response of the building during earthquakes. Accordingly, the properties of a foundation can alter the dynamic characteristics (natural frequency and damping) of the soil-foundation-structure system. In this paper the influence that shallow foundations have on the seismic response of a mid-rise moment resisting building is investigated. For this purpose, a fifteen storey moment resisting frame sitting on shallow footings with different sizes was simulated numerically using ABAQUS software. By adopting a direct calculation method, the numerical model can perform a fully nonlinear time history dynamic analysis to realistically simulate the dynamic behaviour of soil, foundation, and structure under seismic excitations. This three-dimensional numerical model accounts for the nonlinear behaviour of the soil medium and structural elements. Infinite boundary conditions were assigned to the numerical model to simulate free field boundaries, and appropriate contact elements capable of modelling sliding and separation between the foundation and soil elements are also considered. The influence of foundation size on the natural frequency of the system and structural response spectrum was also studied. The numerical results for cases of soil-foundation-structure systems with different sized foundations and fixed base conditions (excluding soil-foundation-structure interaction) in terms of lateral deformations, inter-storey drifts, rocking, and shear force distribution of the structure were then compared. Due to natural period lengthening, there was a significant reduction in the base shears when the size of the foundation was reduced. It was concluded that the size of a shallow foundation influences the dynamic characteristics and the seismic response of the building due to interaction between the soil, foundation, and structure, and therefore design engineer should carefully consider these parameters in order to ensure a safe and cost effective seismic design.