• Title/Summary/Keyword: Particulate Matters(PM)

Search Result 228, Processing Time 0.028 seconds

The Effects of Diesel Exhaust Particulates and Particulate Matters on the ICAM-1 and VCAM-1 Expression in the Lung of Asthma-incuced Mouse (디젤분진 및 미세분진이 천식마우스의 폐조직에서 ICAM-1과 VCAM-1의 발현에 미치는 효과)

  • Li, Tian-Zhu;Lee, Soo-Jin;Jang, Yang-Ho;Lee, Jeong-Hak;Park, Se-Jong;Park, Jun-Hong;Chang, Byung-Joon;Lee, Jong-Hwan;Choe, Nong-Hoon
    • Journal of Life Science
    • /
    • v.17 no.3 s.83
    • /
    • pp.396-401
    • /
    • 2007
  • This research investigated whether exposure of diesel exhaust particulate (DEP) and particulate metter (PM) effect on intercellular. adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1) expression in asthma-induced Balb/c and IL-10 knock out (KO) mouse. Mouse was sensitized with intraperitoneal injection with ovalbumin, followed by challenges with intranasal ovalbumin. After induction of asthma mouse placed in the inhalation chamber and exposed to DEP and PM (10 $mg/m^3$). The evidences of pulmonary inflammation were assessed by immunohistochemical stain and westen blot against ICAM-1 and VCAM-1 in the lung tissue. In the immunohistochemical stain, positive reactions for ICAM-1 and VCAM-1 were much stronger in asthma-induced groups and asthma-induced group with DEP or PM than control groups. Although mild positive reactions were appeared in asthma-induced IL-10 KO mice groups, positive reactions were very strong in the asthma-induced group with DEP or PM. In Western blot, expression of VCAM-1 was increased in asthma-induced group with DEP or PM than asthma-induced groups. In the IL-10 KO mouse, ICAM-1 and VCAM-1 expression were increased in asthma-induced group with DEP or PM than asthma-induced groups. DEP and PM exposure have additive effects on the aggravation of inflammatory signs in the asthma-induced murine model. These results suggest that inhalation of DEP and PM in asthmatic patients may aggravate clinical symptoms.

A Comparative Study on Concentrations of Indoor and Outdoor Particulate Matters in Elementary Schools (초등학교 실내외 미세먼지 농도 비교 연구)

  • Kim, Dae-hyeon;Son, Youn-Suk;Lee, Tae-Jung;Jo, Young Min
    • Korean Journal of Remote Sensing
    • /
    • v.36 no.6_3
    • /
    • pp.1721-1732
    • /
    • 2020
  • Elementary school students spend a lot of time in a school and are more exposed to indoor air pollution. Also the students are physically growing and have a relatively high respiratory rate per unit weight compared to adults, so it is known that there is a high sensitivity to indoor air pollution. Therefore, indoor air quality in a school is becoming an important factor for the student's health. In this study, a correlation analysis using levels of indoor and outdoor Particulate Matter (PM) measured from five elementary schools in Seoul was performed to evaluate the effect of outdoor PM on indoor PM. PM ratio and indoor/outdoor (I/O) ratio were also analyzed to investigate the actual condition of indoor air quality and effect of outdoor PM on indoor PM. As a result, the correlation between indoor and outdoor PM in elementary school was more significant in PM2.5 and PM1 than PM10. In the case of I/O ratio, the I/O ratio of PM10 was higher than that of 1 in four elementary schools except SD (BB:2.21, NS: 1.67, IS: 1.73, SI: 1.17). This indicates that the activity of students has a great effect on the concentration of indoor PM10.

Effects of Resveratrol and Resveratryl Triacetate on The Inflammatory Responses of Human Epidermal Keratinocytes Exposed to Airborne Particulate Matter PM10 (대기 미립자 물질 PM10에 노출된 인간 표피 각질형성세포의 염증 반응에 대한 레스베라트롤과 레스베라트릴 트라이아세테이트(RTA)의 영향)

  • Choi, Min A;Seok, Jin Kyung;Lee, Jeong-won;Lee, Shin Young;Kim, Young Mi;Boo, Yong Chool
    • Journal of the Society of Cosmetic Scientists of Korea
    • /
    • v.44 no.3
    • /
    • pp.249-258
    • /
    • 2018
  • Airborne pollution causes oxidative damage, inflammation, and premature aging of skin. Resveratrol is a polyphenol compound that has various biological activities such as antioxidant, anti-inflammation, and anti-melanogenic activities but it is unstable to heat and light. Resveratryl triacetate (RTA) is a new cosmetic ingredient that is more stable than resveratrol and its skin safety and whitening efficacy have been reported previously. The purpose of this study was to examine the effects of resveratrol and resveratryl triacetate (RTA) on the inflammatory responses of human epidermal keratinocytes (HEKs) exposed to airborne particulate matters with a diameter of < $10{\mu}m$ (PM10). Cultured HEKs were exposed to PM10 in the absence or presence of resveratrol and RTA. Assays were undertaken to determine cell viability, the production of reactive oxygen species (ROS), and the expression of inflammatory cytokines. PM10 treatment decreased cell viability, and increased the expression of pro-inflammatory cytokines such as tumor necrosis $factor-{\alpha}$ ($TNF-{\alpha}$), $interleukin-1{\beta}$ ($IL-1{\beta}$), interleukin-6 (IL-6), and interleukin-8 (IL-8). Resveratrol and RTA reduced cell death and ROS production induced by PM10. PM10-induced mRNA expression of the inflammatory cytokines was either attenuated (IL-6), or enhanced ($IL-1{\beta}$), or unaffected ($TNF-{\alpha}$ and IL-8) by resveratrol and RTA. PM10-induced IL-6 protein expression was attenuated by resveratrol and RTA. This study suggests that resveratrol and RTA have activities regulating cell damage and inflammatory responses of the skin exposed to airborne particulate matters.

The Combustion and Emission Characteristics with Increased Fuel Injection Pressure in a Gasoline Direct Injection Engine (가솔린 직접 분사식 엔진에서 연료 분사 압력 증가에 따른 연소 및 배기 배출물 특성)

  • Lee, Junsun;Lee, Yonggyu
    • Journal of ILASS-Korea
    • /
    • v.22 no.1
    • /
    • pp.1-7
    • /
    • 2017
  • Recently, Performance and fuel efficiency of gasoline engines have been improved by adopting direct injection (DI) system instead of port fuel injection (PFI) system. However, injecting gasoline fuel directly into the cylinder significantly reduces the time available for mixing and evaporation. Consequently, particulate matters(PM) emissions increase. Moreover, as the emission regulations are getting more stringent, not only the mass but also the total number of PM should be reduced to satisfy the Euro VI regulations. Increasing the fuel injection pressure is one of the methods to meet this challenge. In this study, the effects of increased fuel injection pressures on combustion and emission characteristics were experimentally examined at several part load conditions in a 1.6 liter commercial gasoline direct injection engine. The main combustion durations decreased about $2{\sim}3^{\circ}$ in crank angle base by increasing the fuel injection pressure due to enhanced air-fuel mixing characteristics. The exhaust emissions and number concentration distributions of PM with particle sizes were also compared. Due to enhanced combustion characteristics, THC emissions decreased, whereas NOx emissions increased. Also, the number concentrations of PM, larger than 10 nm, also significantly decreased.

Visibility Impairment by Atmospheric Fine Particles in an Urban Area

  • Kim, Young J.;Kim, Kyung W.
    • Journal of Korean Society for Atmospheric Environment
    • /
    • v.19 no.E3
    • /
    • pp.99-120
    • /
    • 2003
  • Visibility impairment in an urban area is mainly caused by airborne fine particulate matters. Visibility in a clean air environment is more sensitive to the change of PM$_{2.5}$ particle concentrations. However, a proportionally larger reduction in fine particle concentration is needed to achieve a small increment of visibility improvement in polluted areas. Continuous optical monitoring of atmospheric visibility and extensive aerosol measurements have been made in the urban atmosphere of Kwangju, Korea. The mean for fine particulate mass from 1999 to 2002 at Kwangju was measured to be 23.6$\pm$20.3 $\mu\textrm{g}$/㎥. The daily average seasonal visual range was measured to be 13.1, 9.2, 11.0, and 13.9 km in spring, summer, fall, and winter, respectively. The mean light extinction budgets by sulfate, nitrate, organic carbon, and elemental carbon aerosol were observed to be 27, 14, 22, and 12%, respectively. It is highly recommended that a new visibility standard and/or a fine particle standard be established in order to protect the health and welfare of general public. Much more work needs to be done in visibility studies, including long-term monitoring of visibility, improvement of visibility models, and formulating integrated strategies for managing fine particles to mitigate the visibility impairment and climate change.e.

Characteristics of PM2.5 and PM10 Concentration in Pusan Area (부산지역 PM2.5와 PM10의 농도 특성)

  • Kim, Sang-Youl;Cheong, Jang-Pyo;Yi, Seung-Muk
    • Journal of Korean Society of Environmental Engineers
    • /
    • v.22 no.6
    • /
    • pp.1159-1170
    • /
    • 2000
  • It is necessary to improve the ambient air quality through the proper treatment and control of pollutants by designating air pollutants to regulatory ones. Especially, human took a concern for particulate matters which raised visibility reduction, public health effects and injury of property for urban areas. In order to reduce the effect of particulate matters, we need to establish proper control strategies based on the concentration characteristics of particulate matters. In this study. to evaluate the characteristics of $PM_{2.5}$ and $PM_{10}$. thirty-eight samples of $PM_{2.5}$ and $PM_{10}$ were collected at Nam-Gu sampling site where continuous air monitoring system has been operated, from May, 1999 to November, 1999, and their concentrations for the mass and anion components($Cl^-$, $NO_3{^-}$, $SO_4{^{2-}}$) were analyzed. The important conclusions obtained in this study were as followings. Total average mass concentrations of $PM_{2.5}$ and $PM_{10}$ were 35.016 and $50.293{\mu}g/m^3$ respectively. and $PM_{2.5}/PM_{10}$ ratio was calculated 0.692. Total average concentrations of anion components in $PM_{2.5}$ were $1.581(Cl^-)$, $3.690(NO_3{^-})$ and $12.825(SO_4{^{2-}}){\mu}g/m^3$ and those in $PM_{10}$ were $2.471(Cl^-)$, $5.819(NO_3{^-})$ and $14.414(SO_4{^{2-}}){\mu}g/m^3$ respectively. From the correlations analysis. the correlation coefficient between mass concentration of $PM_{2.5}$ and $PM_{10}$ was calculated as 0.945. The correlation coefficients between $PM_{2.5}$ and anion components were analyzed as $Cl^-$(0.025), $NO_3{^-}$(0.788) and $SO_4{^{2-}}$(0.500) respectively, and the correlation coefficients between $PM_{10}$ and anion components were analyzed as $Cl^-$(-0.019), $NO_3{^-}$(0.806) and $SO_4{^{2-}}$)(0.535) respectively.

  • PDF

Concentration and Properties of Particulate Matters (PM10 and PM2.5) in the Seoul Metropolitan (서울시 지하철 시스템 내의 입자상물질(PM10, PM2.5) 농도 특성)

  • Lee, Tae-Jung;Lim, Hyoji;Kim, Shin-Do;Park, Duck-Shin;Kim, Dong-Sool
    • Journal of Korean Society for Atmospheric Environment
    • /
    • v.31 no.2
    • /
    • pp.164-172
    • /
    • 2015
  • Seoul subway plays an important part for the public transportation service in Seoul metropolitan area. As the subway system is typically a closed environment, frequent air pollution problems occurred and passengers get malhealth impact. Especially particulate matters (PM) is well known as one of the major pollutants in subway environments. The purpose of this study was to compare the concentrations of $PM_{10}$ and $PM_{2.5}$ in the Seoul subway system and to provide fundamental data in order to management of subway system. $PM_{10}$ and $PM_{2.5}$ samples were collected in the M station platform and tunnel of Subway Line 4 in Seoul metropolitan and in an outdoor location close to it from Apr. 21, 2010~Oct. 27, 2013. The samples collected on teflon filters using $PM_{10}$ and $PM_{2.5}$ mini-volume portable samplers and PM sequential sampler. The PM contributions were $48.6{\mu}g/m^3$ (outdoor), $84.6{\mu}g/m^3$ (platform) and $204.8{\mu}g/m^3$ (tunnel) for $PM_{10}$, and $34.6{\mu}g/m^3$ (outdoor), $49.7{\mu}g/m^3$ (platform) and $83.1{\mu}g/m^3$ (tunnel) for $PM_{2.5}$. The $PM_{10}$ levels inside stations and outdoors are poorly correlated, indicating that $PM_{10}$ levels in the metro system are mainly influenced by internal sources. In this study, we compared PM concentrations before and after operation of ventilation and Electrostatic Precipitator (EP). Despite the increased PM concentration at outdoor, $PM_{10}$ concentration at platform and tunnel showed the 31.2% and 32.3% reduction efficiency after operation the reduction system. The overall results of this study suggest that the installation and operation of the ventilating system and EP should have served as one of the important components for maintaining the air quality in the subway system.

Inhalation Toxicity of Particulate Matters Doped with Arsenic Induced Genotoxicity and Altered Akt Signaling Pathway in Lungs of Mice

  • Park, Jin-Hong;Kwon, Jung-Taek;Minai-Teherani, Arassh;Hwang, Soon-Kyung;Chang, Seung-Hee;Lim, Hwang-Tae;Cho, Hyun-Seon;Cho, Myung-Haing
    • Toxicological Research
    • /
    • v.26 no.4
    • /
    • pp.261-266
    • /
    • 2010
  • In the workplace, the arsenic is used in the semiconductor production and the manufacturing of pigments, glass, pesticides and fungicides. Therefore, workers may be exposed to airborne arsenic during its use in manufacturing. The purpose of this study was to evaluate the potential toxicity of particulate matters (PMs) doped with arsenic (PMs-Arsenic) using a rodent model and to compare the genotoxicity in various concentrations and to examine the role of PMs-Arsenic in the induction of signaling pathway in the lung. Mice were exposed to PMs $124.4{\pm}24.5\;{\mu}g/m^3$ (low concentration), $220.2{\pm}34.5\;{\mu}g/m^3$ (middle concentration), $426.4{\pm}40.3\;{\mu}g/m^3$ (high concentration) doped with arsenic $1.4\;{\mu}g/m^3$ (Low concentration), $2.5\;{\mu}g/m^3$ (middle concentration), $5.7\;{\mu}g/m^3$ (high concentration) for 4 wks (6 h/d, 5 d/wk), respectively in the whole-body inhalation exposure chambers. To determine the level of genotoxicity, Chromosomal aberration (CA) assay in splenic lymphocytes and Supravital micronucleus (SMN) assay were performed. Then, signal pathway in the lung was analyzed. In the genotoxicity experiments, the increases of aberrant cells were concentration-dependent. Also, PMs-arsenic caused peripheral blood micronucleus frequency at high concentration. The inhalation of PMs-Arsenic increased an expression of phosphorylated Akt (p-Akt: protein kinase B) and phpsphorylated mammalian target of rapamycin (p-mTOR) at high concentration group. Taken together, inhaled PMs-Arsenic caused genotoxicity and altered Akt signaling pathway in the lung. Therefore, the inhalation of PMs-Arsenic needs for a careful risk assessment in the workplace.

Assesment of Indoor Air Quality within Public Transport Vehicles operating in specified locations throughout Seoul (서울 일부 지역 교통수단의 실내 공기질 평가)

  • Sohn Jong-Ryeul;Choi Dal-Woong;Choi Jung-Sook;Woo Wan-Gi
    • Journal of environmental and Sanitary engineering
    • /
    • v.21 no.1 s.59
    • /
    • pp.12-20
    • /
    • 2006
  • This paper was conducted concerning the degree of indoor air quality in public transport vehicles such as taxicabs, buses and subway trains, as sampled through the active participation of drivers and passengers in Seoul between 13th August 2005 and 2nd November 2005. The results were summarized as follows: 1. Among the measured substances especially respirable particulate matters ($PM_{10}$), total bacteria counts (TBC) and carbon dioxide ($CO_2$) exceeded the standard level of $150{\mu}g/m^3,\;800CFU/m^3$ and 1000ppm. 2. The concentration of carbon dioxide ($CO_2$) in taxi recorded 2491ppm, which is more than the standard amount of 1000ppm. This level was comparatively higher than all other public transportation methods. Total bacteria counts (TBC) in bus and subway recorded $1082CFU/m^3\;and\;1856CFU/m^3$, respectively. 3. The drivers who regularly work long hours showed the higher concern about contamination of the air inside the public transport vehicles and they considered it to be worse than the air outside. In contrast, the general public showed less concern about the air quality inside the public transport vehicles. However, they too acknowledged that the quality of the air inside the public transport vehicles was poor. In regards to the degree of indoor air quality in the public transport vehicles, a counterplan must be implemented urgently to effectively combat the excessive levels of $PM_{10}$, microorganism and $CO_2$. We need to gather more conclusive evidence pertaining to other possible contaminants and influencing factors.

The Research for effect of lubricant oil aging on environmental performance (자동차 윤활유의 성상 및 열화가 환경성에 미치는 영향 연구)

  • Kim, Jeong-Hwan;Kim, Ki-Ho;Ha, Jong-Han;Jin, Dong-Young;Myung, Cha-Lee;Jang, Jin-Young
    • Journal of the Korean Applied Science and Technology
    • /
    • v.34 no.1
    • /
    • pp.12-24
    • /
    • 2017
  • The main purpose of this research is for the investigation on the impact of engine oil aging on PM and DPF. It is widely known that lubricant specifications and consumption from an ICE have significantly influenced on the regulated and unregulated harmful emissions as the engine operating conditions. Considering DPF clogging phenomena with lubricant-derived soot/ash components, simulated aging mode for the DPF was newly designed for engine dynamometer testing. PM/ash accumulation cycle were developed in reflecting real-world engine operating conditions for the increment of engine oil consumption and natural DPF regeneration for the ash accumulation. The test duration for DPF aging reached around 100hrs with high- and low-SAPS engine oils, respectively. Using high SAPs engine oil made more PM/ash accumulation compared with low SAPs engine oils and it could accelerate fouling of EGR in engine. Fouling of EGR made effects on more harmful exhaust gases emissions. The test results on engine lubricant under engines operating conditions will deliver for the establishment of regulated and unregulated toxic emissions policy, lubricant quality standard.