• Title/Summary/Keyword: Particulate

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Effect of Gelatin Particles on Cell Proliferation in Polymer Scaffolds Made Using Particulate Leaching Technique. (Particulate Leaching 기법을 사용한 Polymer Scaffold 상의 세포증식에 있어서 젤라틴 입자의 효과)

  • 서수원;신지연;김진훈;김진국;길광현
    • Journal of Biomedical Engineering Research
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    • v.25 no.1
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    • pp.1-4
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    • 2004
  • On the background of general idea and technique of bioscience, medicine and engineering, tissue engineering aim at maintenance, improvement and repair of human body function through manufacturing and transplantation of artificial tissue and organ exchangeable human body. Basic material used in the area is scaffold that aid tissue and organ formation. Making scaffold, solvent-casting and particulate leaching technique is widely used in manufacturing of porous polymer scaffold. There are many types of particle including salt and gelatin. Salt is a most commonly used particulate because it is easily available and very easy to handle and gelatin particle is another candidate for this method because it is known as a material, which enhances cell attachment and proliferation. But there is no comparative study of two kinds of materials. In this study we compared the biocompatibility of the two scaffolds made from salt(salt scaffold) and gelatin particle (gelatin scaffold). These results demonstrated that gelatin scaffold showed better attachment of cells at the initial stage and better proliferation of cells. The better performance of gelatin scaffold is contributed to the better connection of pores in the same porosity.

The Concentration of TSP and Heavy Metals in the Indoor Air of Local PC Rooms (지방 일개도시 PC방에서의 실내공기중 TSP농도와 TSP내 중금속 농도)

  • Cha Hyun Su
    • Journal of Korean Public Health Nursing
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    • v.16 no.1
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    • pp.190-200
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    • 2002
  • This study was carried out to investigate and analyze TSP of the PC rooms. The concentration of the total suspended particulate and heavy metals contained in the total suspended particulate of the 15 PC rooms located in one local city were measured. The statistical correlation coefficients between the total suspended particulate and factors of the indoor condition (number of fan or size of pc room, illumination), between the heavy metals and factors of the indoor condition were studied. The results are as follows: 1. The factors of the indoor condition of the 15 PC rooms are as follows. Average illumination was 24 luxes. Average number of computers installed were 37. Average number of the fans was 7. and the size of investigated PC rooms was $139.94m^2$. 2. The mean age of the subjects was 21.8 years old. they $(51.5\%)$ used the 15 pc rooms for fewer than 2 hours per one day. 3. The mean concentration of total suspended particulate (TSP) is lower in the evening ${139.085\;(2.462)\;{\mu}g/m^3}$ than the night ${166.216(2.609){\mu}g/m^3}$. 4. The mean concentration of total suspended particulate was industrial work area) residential area) commercial area. 5. The distribution of heavy metals were indicated as Zn>Cr>Pb>Cd in the indoor air at PC rooms. and the concentration rate of Zn was the highest among heavy metals. but this increase didn't show any relationship with many factors of indoor condition (number of fan or size of pc room, lighting) 6. The concentration of TSP & heavy metals didn't have any relationship between the factors of indoor environment (number of fans, size of pc room, lighting).

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The Effect of Autogenous Demineralized Dentin Matrix and Interleukin-6 on bone Regeneration

  • Jang, Won Seok;Kim, Min Gu;Hwang, Dae Suk;Kim, Gyoo Cheon;Kim, Uk Kyu
    • International Journal of Oral Biology
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    • v.42 no.4
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    • pp.203-211
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    • 2017
  • The aim of this study was to evaluate the role of demineralized and particulate autogenous tooth, and interleukin-6 in bone regeneration. A demineralized and particulate autogenous tooth was prepared and human osteoblast-like cells (MG63) and human osteosarcoma cells were inoculated into the culture. The rate of cell adhesion, proliferation and mineralization were examined, and the appearance of cellular attachment was observed. An 8 mm critical size defect was created in the cranium of rabbits. Nine rabbits were divided into three groups including: An experimental group A (3 rabbits), in which a demineralised and particulate autogenous tooth was grafted; an experimental group B (3 rabbits), in which a demineralized, particulate autogenous tooth was grafted in addition to interleukin-6 (20 ng/mL); and a control group. The rabbits were sacrificed at 1, 2, 4 and 6 weeks for histopathological examination with H-E and Masson's Trichrome, and immunohistochemistry with osteocalcin. The cell-based assay showed a higher rate of cell adhesion, mineralization and cellular attachment in the experimental group A compared with the control group. The animal study revealed an increased number of osteoclasts, newly formed and mature bones in the experimental group A compared with the control group. Eventually, a higher number of osteoclasts were observed in the experimental group B. However, the emergence of newly formed and mature bone was lower than in the experimental group A. The current results suggest that treatment with demineralized and particulate autogenous tooth and interleukin-6 is not effective in stimulating bone regeneration during the bone grafting procedure.

Effects on Preventive Behavior Intention to Particulate Matter by Risk Perception Attitude and Anxiety : Focus on Adoption of RPA Model (위험인식태도와 불안이 미세먼지 예방행동의도에 미치는 영향: RPA모델 적용을 중심으로)

  • Ko, Du Hee;Song, Hae Ryong
    • Journal of Digital Convergence
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    • v.18 no.10
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    • pp.517-526
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    • 2020
  • This study aimed to understand the effects on preventive behavior intention to particulate matter by risk perception attitude and anxiety. Also, to expand applicable target and range of RPA model, add anxiety. To measure main variables of RPA model, did a survey with 570 college students. With a data, analyzed by correlation, one-way ANOVA and three-way ANOVA. As a result, perceived risk and efficacy effect on intention to preventive action and information seeking. And an anxiety factor effects on intention to preventive action and information seeking also. And distinguished 4 groups of RPA model, there were meaningful differences between intention to preventive action and information seeking by groups, and a factor of anxiety effects certain groups. As a result, it can suggest how to plan and enforce message on preventive campaign of particulate matter. In follow research, with social psychological factors, it will helpful to identify health activities about particulate matters.

Crack Resistance Behavior Using Digital Image Correlation and Crack Tip Opening Angle on Particulate Reinforced Composite (디지털 화상관련법 및 균열선단열림각도를 이용한 입자강화 복합재료의 균열저항거동)

  • Na, Seong Hyeon;Lee, Jeong Won;Kim, Jae Hoon
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.40 no.12
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    • pp.1021-1026
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    • 2016
  • In this study, crack resistance is evaluated by the crack tip opening angle (CTOA) using a wedge splitting test (WST) on a viscoelastic particulate reinforced composite based on an HTPB binder. Generally, CTOA, as a function of crack extension, is used in order to determinate fracture resistance and has a steady state relative angle. Digital image correlation (DIC) is used to measure the crack tip opening displacement (CTOD) and crack extension for the critical crack tip opening angle (CTOAc). In these results, the CTOAc value of a particulate reinforced composite tends to approach a constant angle after a small amount of crack extension. The CTOAc value increases with decreasing temperature, from $50^{\circ}C$ to $-40^{\circ}C$. These CTOAc values may be used to measure fracture mechanics parameters for particulate reinforced composite.

Numerical Study of Impact for Particulate Matter Reduction Device According to Installation of Perforated Plate and Mixer on Marine Diesel Engine (선박용 디젤엔진의 미세먼지저감 장치에 다공판과 믹서의 장착이 미치는 영향에 대한 수치해석적 연구)

  • Yun, Byoungkyu;Cho, Sanghyun;Ryu, Younghyun
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.25 no.7
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    • pp.968-973
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    • 2019
  • This study presents the characteristics of a pressure drop and uniformity index for a particulate matter reduction device with a perforated plate and mixer for marine diesel engines. The perforated plate and mixer equipped on the particulate matter reduction device induce an increase of exhaust gas reduction performance by increasing the uniformity index. Whereas, the perforated plate induces pressure drop increases in the particulate matter reduction device. Therefore to calculate the effect of the uniformity index and pressure drop of the perforated plates and mixer, this study combines several cases using five types of perforated plates and one type of mixer. Consequently, these results were analyzed to determine the optimized type and position of the perforated plate and mixer.

Comparative Analysis of the Binary Classification Model for Improving PM10 Prediction Performance (PM10 예측 성능 향상을 위한 이진 분류 모델 비교 분석)

  • Jung, Yong-Jin;Lee, Jong-Sung;Oh, Chang-Heon
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.25 no.1
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    • pp.56-62
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    • 2021
  • High forecast accuracy is required as social issues on particulate matter increase. Therefore, many attempts are being made using machine learning to increase the accuracy of particulate matter prediction. However, due to problems with the distribution of imbalance in the concentration and various characteristics of particulate matter, the learning of prediction models is not well done. In this paper, to solve these problems, a binary classification model was proposed to predict the concentration of particulate matter needed for prediction by dividing it into two classes based on the value of 80㎍/㎥. Four classification algorithms were utilized for the binary classification of PM10. Classification algorithms used logistic regression, decision tree, SVM, and MLP. As a result of performance evaluation through confusion matrix, the MLP model showed the highest binary classification performance with 89.98% accuracy among the four models.

A Study on the Distribution Characteristics and Countermeasures of Concentrations of Ambient PM10 and PM2.5 in Yangju, South Korea

  • Dohun Lim;Yoonjin Lee
    • Economic and Environmental Geology
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    • v.55 no.6
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    • pp.701-716
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    • 2022
  • This study investigated the distribution behaviors of PM2.5 and PM10 at two air quality monitoring sites, Go-eup (GO) and Backseokeup (BS), located in Yangju City, South Korea. The amounts of emissions sources of pollutants were analyzed based on the Clean Air Policy Support System (CAPSS), and the contribution rates of neighboring cities were enumerated in Yangju. Yangju has a geological basin structure, and it is a city with mixed urban and rural characteristics. The emission concentration of particulate matter was affected by geological and seasonal factors for all sites observed in this study. Therefore, these factors should be considered when establishing policies related to particulate matter. Because the official GO and BS station sites in Yangju are both situated in the southern part of the city, the representativeness of both stations was checked using correlation analysis for the measurement of PM2.5 and PM10 by considering two more sites-those of Bongyang-dong (BY) and the Gumjun (GJ) industrial complex. The data included discharge amounts for business types 4 and 5, which were not sufficiently considered in the CAPSS estimates. Because the 4 and 5 types of businesses represent over 92.6% of businesses in this city, they are workplaces in Yangju that have a significant effect on the total air pollutant emission. These types of businesses should be re-inspected as the main discharge sources in industry, and basic data accumulation should be carried out. Moreover, to manage the emission of particulate matter, attainable countermeasures for the main sources of these emissions should be prepared in a prioritized fashion; such countermeasures include prohibition of backyard burning, supervision of charcoal kilns, and management of livestock excretions and fugitive dust in construction sites and on roads. The contribution rates by neighboring cities was enumerated between 6.3% and 10.9% for PM2.5. Cooperation policies are thought to be required with neighboring cites to reduce particulate matter.

Association between ambient particulate matter levels and hypertension: results from the Korean Genome and Epidemiology Study

  • Sewhan Na;Jong-Tae Park;Seungbeom Kim;Jinwoo Han;Saemi Jung;Kyeongmin Kwak
    • Annals of Occupational and Environmental Medicine
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    • v.35
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    • pp.51.1-51.15
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    • 2023
  • Background: Recently, there has been increasing worldwide concern about outdoor air pollution, especially particulate matter (PM), which has been extensively researched for its harmful effects on the respiratory system. However, sufficient research on its effects on cardiovascular diseases, such as hypertension, remains lacking. In this study, we examine the associations between PM levels and hypertension and hypothesize that higher PM concentrations are associated with elevated blood pressure. Methods: A total of 133,935 adults aged ≥ 40 years who participated in the Korean Genome and Epidemiology Study were analyzed. Multiple linear regression analyses were conducted to investigate the short- (1-14 days), medium- (1 and 3 months), and long-term (1 and 2 years) impacts of PM on blood pressure. Logistic regression analyses were conducted to evaluate the medium- and long-term effects of PM on blood pressure elevation after adjusting for sex, age, body mass index, health-related lifestyle behaviors, and geographic areas. Results: Using multiple linear regression analyses, both crude and adjusted models generated positive estimates, indicating an association with increased blood pressure, with all results being statistically significant, with the exception of PM levels over the long-term period (1 and 2 years) in non-hypertensive participants. In the logistic regression analyses on non-hypertensive participants, moderate PM10 (particulate matter with diameters < 10 ㎛) and PM2.5 (particulate matter with diameters < 2.5 ㎛) levels over the long-term period and all high PM10 and PM2.5 levels were statistically significant after adjusting for various covariates. Notably, high PM2.5 levels of the 1 year exhibited the highest odds ratio of 1.23 (95% confidence interval: 1.19-1.28) after adjustment. Conclusions: These findings suggest that both short- and long-term exposure to PM is associated with blood pressure elevation.

Association between exposure to particulate matter and school absences in Korean asthmatic adolescents

  • Seongmin Jo;Kiook Baek;Joon Sakong;Chulyong Park
    • Annals of Occupational and Environmental Medicine
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    • v.34
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    • pp.21.1-21.13
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    • 2022
  • Background: Because particulate matter (PM) and asthma are closely related, the prevalence of school absence among adolescents with asthma can be affected by the concentration of PM. We aimed to investigate the relationship between school absences due to asthma and the total number of days that the PM concentration exceeded the standard. Methods: We used the data from the 16th Korea Youth Risk Behavior Survey and the PM levels of 17 metropolitan cities and provinces gathered from the AirKorea. Information on the characteristics of asthmatic adolescents and the prevalence of school absence was obtained using a questionnaire, while the PM levels based on the total number of days with poor and very poor PM grades were collected from the AirKorea website. Both χ2 test and logistic regression analysis were performed using the weights presented in the original dataset. Results: In the case of particulate matter of 10 microns in diameter or smaller (PM10), the odds ratio (OR) after adjusting for confounders (sex, school year, body mass index, smoking history, diagnosis of allergic rhinitis, diagnosis of atopic dermatitis and city size) was 1.07 (95% confidence interval [CI]: 1.01-1.13) for absents due to asthma when the total days of poor and very poor grades of PM10 (81 ㎍/m3 or higher) increased by 1 day. In the analysis of particulate matter of 2.5 microns in diameter or smaller (PM2.5), the OR after adjusting for confounders was 1.01 (95% CI: 1.00-1.03) for absents due to asthma when the total number of days with poor and very poor PM2.5 grades (36 ㎍/m3 or higher) increased by 1 day. Conclusions: A significant association was observed between the total number of days of poor and very poor PM10 and PM2.5 grades and school absence due to asthma; PM can cause asthma exacerbation and affect the academic life.