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A Clinical Report of the Patient with Limited-Stage Small Cell Lung Cancer (제한병기 소세포폐암 환자의 치험례 임상보고)

  • Park, Jung-Sup;Rhee, See-Hyung;Yim, Young-Nam;Jung, Ki-Young;Jun, Chan-Young;Park, Chong-Hyeong;Kim, Dong-Woo
    • The Journal of Internal Korean Medicine
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    • v.26 no.3
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    • pp.677-684
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    • 2005
  • Objectives : This study was designed to evaluate the effects of oriental herb medicine therapy on a limited stage small ell lung cancer(SCLS) patient. Methods : The medical record of this case of SCLS was researched. The patient had been treated with oriental herb medicine for five months continuously in OPD. Clinical data was analyzed and the mass of small cell lung cancer before and after oriental herb medicine therapy was compared using X-ray and CT scan of the whole body in order to determine metastasis. Result : After 5 months of oriental herb medical treatment, most of symptoms disappeared or improved. The small cell lung cancer patially receeded and improvements were mainly seen in sputum, coughing, insomnia, diarrhea, and performance status. Conclusion : The study suggests that oriental herb medicine therapy effects the tumor size by causing remission and Improving health and relieving symptoms, and also positively effects the quality of life as a supportive or curative therapy for SCLC patients.

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A Size Change of Bone Defect Area after Autogenous Calvarial Bone Graft (자가 머리뼈 이식 후 뼈결손부의 면적 변화)

  • Hyun, Kyung Bae;Kim, Dong Suk;Yoo, Sun Kook;Kim, Hee Joung;Kim, Yong Oock;Park, Be-young Yun
    • Archives of Plastic Surgery
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    • v.32 no.4
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    • pp.467-473
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    • 2005
  • Calvarial bone grafting in craniomaxillofacial trauma and facial reconstructive surgery is now widely recognized and accepted as a standard procedure. One of the commonly reported problems of calvarial bone graft is the contour defect caused by partial resorption of the graft. But, there are few reports that discuss the fate of the calvarial bone graft based on the quantitative data. In this article, the changes of grafted calvarial bone were evaluated using 3-dimensional computed tomography(CT). 9 patients were observed with the CT scans at 2mm thickness immediately after operation and at the time of last follow-up. The area of the bone defect was segmented on the 3-dimensional CT image and calculated by AnalyzeDirect 5.0 software. The immediate postoperative bone defect area of the recipient site and the donor site were $612.9mm^2$ and $441.5mm^2$, respectively, which became $1028.1mm^2$ and $268.8mm^2$, respectively at the last follow-up. In conclusion, the bone defect area was less increased on the donor site of calvarial bone graft than on the recipient site. And the CT scan is a valuable imaging method to assess and follow-up the clinical outcome of calvarial bone grafting.

Surgical Correction of Thoracic Aortic Aneurysm Associated with Coronary Artery Disease A Case Report -A Case Report- (관상동맥질환을 동반한 대동맥류 수술치험 1례)

  • 우종수;서정욱
    • Journal of Chest Surgery
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    • v.30 no.7
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    • pp.724-728
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    • 1997
  • We experienced a case of thoracic aortic aneurysm combined with coronary artery disease. A 68-year-old man complained of anginal pain in the left anterior chest and nonspecific pain in the posterior chest. The aneurysm was extending from left subclavian artery to the diaphragm and sign of impending rupture was noted in the chest CT. Coronary angiograms r vealed significant obstruction of left circumflex coronary artery(>95%) and left anterior descending artery(>50%). Exposure was obtained through the left posterolateral thoracotomy incision in the 4th intercostal space and then partial femoro-femoral cardiopulmonary bypass was established. After aortic cross clamping, the aneurysmal sac was opened and repaired with interposition of 26 mm Hemashield graft. Under the beating heart with femoro-femoral cardiopulmonary bypass, aorto-left circumflex coronary bypass with autogenous saphenous vein used as conduit was performed. Postoperatively multiple cerebral infarction ensued due to intraoperative hypovolemic shock and hypoxic brain damage during cardiopulmonary bypass. Currently, the patient's mental status is drowsy and in an improving state.

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Performance Evaluation of Conical Picks for Roadheader in Copper Mines (구리광산에 적용된 부분단면굴착기용 국산 코니컬 픽커터의 성능평가 연구)

  • Choi, Soon-Wook;Chang, Soo-Ho;Lee, Chulho;Lee, Gyu-Phil;Bae, Young Hwan;Ha, Tae-Wook
    • Tunnel and Underground Space
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    • v.25 no.6
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    • pp.496-504
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    • 2015
  • Roadheader that excavates ground using pick cutters installed on the cutting head is one of the partial-face machines. A conical cutter among pick cutters is excavation tool decreasing the loss of cutter using tungsten carbide insert at the tip of the cutter and it has been widely used in the roadheaders. In this study, durability performance for three kinds of conical cutters was evaluated in copper mines composed of Manto and conglomerate. After field test, the visual inspection as well as the weight loss measurement of pick cutters was carried out to investigate the damage of pick cutters. In addition, CT scan and SEM were performed to check whether or not crack and apertures in pick cutters. As results, the conical cutter with hardfacing was evaluated as having the best durability performance and it was unable to find cracks in all cutters investigated.

SVC Syndrome Caused by Leiomyosarcoma of SVC - A Case Report - (상대정맥에 발생한 평활근육종의 수술 - 1례 보고 -)

  • 손영상;류세민;손호성;조원민;황재준;최영호;김학제;심재정;조성준
    • Journal of Chest Surgery
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    • v.35 no.3
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    • pp.235-238
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    • 2002
  • Among the causes of SVC syndrome, intraluminal tumor, especially the leiomyosarcoma is very rare. We report a 39 year old female patient who had been suffering from headache and facial edema for 6 weeks before admission. On physical examination, facial edema and venous engorgement on upper extermities and upper chast wall were showed. The chest CT scan and SVC cavogram showed a long intraluminal mass lesion resulting in a near total obstruction of the SVC Surgery was performed through median sternotomy. For complete resection of the tumor and thrombus, we used partial and total CPB. The follow up SVC cavogram revealed no abnormality 14 months after the operation.

Differentiation of Beef and Fish Meals in Animal Feeds Using Chemometric Analytic Models

  • Yang, Chun-Chieh;Garrido-Novell, Cristobal;Perez-Marin, Dolores;Guerrero-Ginel, Jose E.;Garrido-Varo, Ana;Cho, Hyunjeong;Kim, Moon S.
    • Journal of Biosystems Engineering
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    • v.40 no.2
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    • pp.153-158
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    • 2015
  • Purpose: The research presented in this paper applied the chemometric analysis to the near-infrared spectral data from line-scanned hyperspectral images of beef and fish meals in animal feeds. The chemometric statistical models were developed to distinguish beef meals from fish ones. Methods: The meal samples of 40 fish meals and 15 beef meals were line-scanned to obtain hyperspectral images. The spectral data were retrieved from each of 3600 pixels in the Region of Interest (ROI) of every sample image. The wavebands spanning 969 nm to 1551 nm (across 176 spectral bands) were selected for chemometric analysis. The partial least squares regression (PLSR) and the principal component analysis (PCA) methods of the chemometric analysis were applied to the model development. The purpose of the models was to correctly classify as many beef pixels as possible while misclassified fish pixels in an acceptable amount. Results: The results showed that the success classification rates were 97.9% for beef samples and 99.4% for fish samples by the PLSR model, and 85.1% for beef samples and 88.2% for fish samples by the PCA model. Conclusion: The chemometric analysis-based PLSR and PCA models for the hyperspectral image analysis could differentiate beef meals from fish ones in animal feeds.

Growth of α-Ga2O3 Epitaxial Films on Al2O3 by Halide Vapor Pressure Epitaxy

  • Lee, Daejang;Cha, An-Na;Park, Junseong;Noh, Hogyun;Moon, Youngboo;Ha, Jun-Seok
    • Journal of the Microelectronics and Packaging Society
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    • v.26 no.4
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    • pp.113-118
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    • 2019
  • In this study, we investigated the growth of single-crystallinity α-Ga2O3 thin films on c-plane sapphire substrates using halide vapor pressure epitaxy. We also found the optimal growth conditions to suppress the phase transition of α-Ga2O3. Our results confirmed that the growth temperature and partial pressure of the reactive gas greatly influenced the crystallinity. The optimal growth temperature range was about 460~510℃, and the α-Ga2O3 thin films with the highest crystallinity were obtained at a III/VI ratio of 4. The thickness and surface morphology of the thin films was observed by scanning electron microscopy. The film thickness was 6.938 ㎛, and the full width at half maximum of the ω-2θ scan rocking curve was as small as 178 arcsec. The optical band gap energy obtained was 5.21 eV, and the films were almost completely transparent in the near-ultraviolet and visible regions. The etch pit density was found to be as low as about 6.0 × 104 cm-2.

The Loss of Coolant Flow Accident Analysis in Kori-1 (고리1호기 원자로 냉각재 유량상실사고 해석)

  • Kook Jong Lee;Un Chul Lee;Jin Soo Kim;Si Hwan Kim
    • Nuclear Engineering and Technology
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    • v.17 no.4
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    • pp.256-266
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    • 1985
  • The loss of coolant flow accident is analyzed for the pressurized water reactor of Korea Nuclear Unit-1. The loss of coolant flow accident is classified into three types in accordance with its severity; partial loss of coolant flow, complete loss of coolant flow and pump locked rotor accident. Analysis has been carried out in three stages; system transient and average core analysis, DNBR calculation and hot spot analysis. The purpose of developing KTRAN is to simulate the transient fast. For the DNBR calculation, the thermal hydraulic codes, SCAN and COBRA IV-1, are adopted. And for the hot spot analysis, the fuel thermal transient code LTRAN is employed. This code system should be fast responding to the transient analysis. In case the transient occurs, severity comes within a couple of seconds. So response should be fast to accomodate the following sequence of the accident. Unfortunately this purpose could not be achieved by KTRAN. However, the calculated results are well comparable with FSAR results in range. Thereby, the effectiveness of KTRAN code analysis in this type of accident is proven.

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A successful management after preterm delivery in a patient with severe sepsis during third-trimester pregnancy

  • Ra, Moni;Kim, Myungkyu;Kim, Mincheol;Shim, Sangwoo;Hong, Seong Yeon
    • Journal of Yeungnam Medical Science
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    • v.35 no.1
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    • pp.84-88
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    • 2018
  • A 33-year-old woman visited the emergency department presenting with fever and dyspnea. She was pregnant with gestational age of 31 weeks and 6 days. She had dysuria for 7 days, and fever and dyspnea for 1 day. The vital signs were as follows: blood pressure 110/70 mmHg, heart rate 118 beats/minute, respiratory rate 28/minute, body temperature $38.7^{\circ}C$, and oxygen saturation by pulse oximetry 84% during inhalation of 5 liters of oxygen by nasal prongs. Crackles were heard over both lung fields. There were no signs of uterine contractions. Chest X-ray and chest computed tomography scan showed multiple consolidations and air bronchograms in both lungs. According to urinalysis, there was pyuria and microscopic hematuria. She was diagnosed with community-acquired pneumonia and urinary tract infection (UTI) that progressed to severe sepsis and acute respiratory failure. We found extended-spectrum beta-lactamase producing Escherichia coli in the blood culture and methicillin-resistant Staphylococcus aureus in the sputum culture. The patient was transferred to the intensive care unit with administration of antibiotics and supplementation of high-flow oxygen. On hospital day 2, hypoxemia was aggravated. She underwent endotracheal intubation and mechanical ventilation. After 3 hours, fetal distress was suspected. Under 100% fraction of inspired oxygen, her oxygen partial pressure was 87 mmHg in the arterial blood. She developed acute kidney injury and thrombocytopenia. We diagnosed her with multi-organ failure due to severe sepsis. After an emergent cesarean section, pneumonia, UTI, and other organ failures gradually recovered. The patient and baby were discharged soon thereafter.

Clinical Significance of FDG PET-CT Scan at 12 Weeks after Curative Radiation Therapy in Patients with Head and Neck Cancer (두경부암 환자에서 근치적 방사선치료 후 12주 시행한 양전자방출촬영의 임상적 중요성에 대한 연구)

  • Kim, Young-il;Kim, Jun-sang;Kwon, Jeanny;Kim, Sup;Seo, Youngduk;Koo, Bon-seok;Chang, Jae-won;Cho, Moon-June
    • Korean Journal of Head & Neck Oncology
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    • v.37 no.1
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    • pp.17-22
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    • 2021
  • Background/Objectives: To evaluate clinical significance of FDG PET-CT for detection of residual cancer cells after curative radiation therapy or chemoradiotherapy for patients with squamous cell carcinoma (SCC) of Head and Neck Materials & Methods: A retrospective analysis of patients with SCC of Head and neck with curative radiotherapy or chemoradiotherpy between June 2011 and Jan. 2019 was performed. Sixty patients were treated with Intensity-modulated radiotherapy (IMRT). The Metabolic responses were evaluated on the post-treatment FDG PET-CT at 12 weeks after curative radiotherapy completion. Results: Median follow up was 51.5 months (3-102). The overall survival (OS), disease free survival (DFS), local control rate (LCR), and Distant metastasis free survival (DMFS) at 5 years were 80.5%, 80.1%, 87.7% and 89.1%. Metabolic CR was found in 43 (71.7%) and partial metabolic response (PR) was noted in 17 (14.6%). Metabolic CR was significantly correlated with OS, DFS, LCR, and DMFS. On multivariate analysis, Metabolic CR remained significant for DFS and LCR. Conclusion: Metabolic CR on post-radiotherapy FDG PET-CT is highly predictive of increased DFS and LCR in patients with head and neck cancer.