• Title/Summary/Keyword: Partial scan

Search Result 111, Processing Time 0.024 seconds

Detection of Imprinted Quantitative Trait Loci (QTL) for Growth Traits in Pigs

  • Lee, H.K.;Lee, S.S.;Kim, T.H.;Jeon, G.J.;Jung, H.W.;Shin, Y.S.;Han, J.Y.;Choi, B.H.;Cheong, I.C.
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.16 no.8
    • /
    • pp.1087-1092
    • /
    • 2003
  • As an experimental reference population, crosses between Korean native pig and Landraces were established and information on growth traits was recorded. Animals were genotyped for 24 microsatellite markers covering chromosomes 2, 6, and 7 for partial-genome scan to identify chromosomal regions that have effects on growth traits. quantitative trait loci (QTL) effects were estimated using interval mapping by the regression method under the line cross models with a test for imprinting effects. For test of presence of QTL, chromosome-wide and single position significance thresholds were estimated by permutation test and normal significance threshold for the imprinting test were derived. For tests against the Mendelian model, additive and dominance coefficients were permuted within individuals. Thresholds (5% chromosome-wide) against the no-QTL model for the analyzed traits ranged from 4.57 to 4.99 for the Mendelian model and from 4.14 to 4.67 for the imprinting model, respectively. Partial-genome scan revealed significant evidence for 4 QTL affecting growth traits, and 2 out of the 4 QTLs were imprinted. This study demonstrated that testing for imprinting should become a standard procedure to unravel the genetic control of multi-factorial traits. The models and tests developed in this study allowed the detection and evaluation of imprinted QTL.

Factor Analysis of Decreased Score on Coronary Artery Calcium Score (관상동맥 석회화점수 감소 요인 분석)

  • Shim, Jae-Goo;Kim, Yon-Min;Kim, Jin-Woo
    • Journal of the Korean Society of Radiology
    • /
    • v.10 no.4
    • /
    • pp.285-290
    • /
    • 2016
  • The purpose of our study was to retrospectively evaluate the cause of a decreased calcium score of follow-up studies on coronary artery calcium scores (CACs) computed tomography (CT). The subjects were healthy 100 people(85 males $60.6{\pm}6.9$ years, 15 females $67.2{\pm}7.3$ years). The subjects decreased CACs were divided into 4 subgroups depending on Agatston classification, minimal (1-10), mild (11-100), moderate (101-400), severe (400<). As a result of decreased CACs were scan location disagreement 51%, motion artifact 26%, equipment changes 14%, operator mistakes 5%, input miss 2%, image loss 1%, arrhythmia 1%. In the mild group, the most common decreased CACs were 49 people. In the minimal group, the most significant variation reduction has occurred to 6 people. Scan location disagreement was considered a partial volume effects due to the scan starting position. It showed less than 100 CACs a high variation (19.7%) in more than 100 CACs, a lower variation (2.2%), these could be seen that the variation range is different that can be tolerated according to the calcification score. Motion artifact factor was found in 26%, which is so closely related to the preceding tests that affect the higher heart rate like this pulmonary function test, exercise stress test.

Thermodynamic Analysis of the Low- to Physiological-Temperature Nondenaturational Conformational Change of Bovine Carbonic Anhydrase

  • Hollowell, Heather N.;Younvanich, Saronya S.;McNevin, Stacey L.;Britt, B. Mark
    • BMB Reports
    • /
    • v.40 no.2
    • /
    • pp.205-211
    • /
    • 2007
  • The stability curve - a plot of the Gibbs free energy of unfolding versus temperature - is calculated for bovine erythrocyte carbonic anhydrase in 150 mM sodium phosphate (pH = 7.0) from a combination of reversible differential scanning calorimetry measurements and isothermal guanidine hydrochloride titrations. The enzyme possesses two stable folded conformers with the conformational transition occurring at ~30$^{\circ}C$. The methodology yields a stability curve for the complete unfolding of the enzyme below this temperature but only the partial unfolding, to the molten globule state, above it. The transition state thermodynamics for the low- to physiological-temperature conformational change are calculated from slow-scan-rate differential scanning calorimetry measurements where it is found that the free energy barrier for the conversion is 90 kJ/mole and the transition state possesses a substantial unfolding quality. The data therefore suggest that the x-ray structure may differ considerably from the physiological structure and that the two conformers are not readily interconverted.

A Study of the Discharge Characteristics of PDP having Auxiliary Electrodes with High Xe% Working Gas

  • Jang, Jin-Ho;Lee, Don-Kyu;Ok, Jung-Woo;Kim, Deok-Won;Kim, Dong-Hyun;Lee, Hae-June;Lee, Ho-Jun;Par, Chung-Hoo
    • 한국정보디스플레이학회:학술대회논문집
    • /
    • 2007.08b
    • /
    • pp.1189-1192
    • /
    • 2007
  • We propose new driving schemes, asymmetry and long gap mode, of PDP having auxiliary electrode between scan and common electrode. For the asymmetric modes, the auxiliary electrode located nearly center of the primary electrodes is connected to the scan of common electrode during all periods of reset, address and sustain. For the long gap mode, it is electrically disconnected or maintained at dc voltage of Vs/2 during sustain period except the first several sustain pulses. The proposed structure and driving method can provide higher luminous efficacy by minimizing consumption energy. The effectiveness of the new driving schemes has been investigated for various Xe partial pressure conditions.

  • PDF

Deposition condition of NiO deposited on biaxially textured Ni by a MOCVD process (2축 정렬된 Ni 위에 MOCVD법에 의한 NiO의 증착조건)

  • 선종원;김형섭;지봉기;박해웅;홍계원;박순동;정충환;전병혁;김찬중
    • Progress in Superconductivity and Cryogenics
    • /
    • v.4 no.2
    • /
    • pp.5-10
    • /
    • 2002
  • Deposition condition of NiO that is one of Possible buffer layers for YBCO coated conductors was studied. NiO was deposited on textured Ni substrates by a MOCVD (metal-organic chemical vapor deposition) method. The degree of texture, and the surface roughness were analyzed by X-ray Pole figure, atomic force microscope and scanning electron microscope. The (111) and (200) textures were competitively developed , depending on an oxygen partial Pressure(PO2) and deposition temperature (Tp). The (200) textured NiO layer was deposited at Tp=450~47$0^{\circ}C$ and PO2= 1.67 Torr Out-of-Plane ($\omega$-scan) and in-plane ($\Phi$-scan) textures of the (200) NiO films were as good as 10.34$^{\circ}$ and 10.00$^{\circ}$ respectively The AFM surface roughness of NiO was in the range of 3~4.5 nm at PO2=0.91~3.34 Torr and at Tp=47$0^{\circ}C$ , and in the range of 3~13 nm at TP=450~53$0^{\circ}C$ and at PO2=1.67 Torr.

Two case of Stroke patients assume an aspect of Cheiro-oral Syndrome (수구증후군 양상을 보인 뇌졸중 환자 2례)

  • Kang, Gu-Hyeng;Yong, Hyung-Soon;Jung, Yong-Soo;Ko, Seong-Gyu;Park, Kyoung-Hoon
    • The Journal of Internal Korean Medicine
    • /
    • v.22 no.2
    • /
    • pp.257-262
    • /
    • 2001
  • Cheiro-oral syndrome is characterized by a partial sensory disturbance in one hand and the ipsilateral oral comer. Its lesion is on the sensory track, and it is comparatively small. Most studies are case studies. These studies reported less than 10 cases. We studied two cases. In one, we observed intracranial hemorrhage involving left thalamus, posterior limb of internal capsule about 5cc in brain computed tomographic scan. The case was shown paresthesia of the right hand and ipsilateral comer of the mouth. The patient also complained about disturbing dysstereognosis and disorder of graphaesthesia. In the other case, we observed nodular calcification at the left basal ganglia external capsule in brain computed tomographic scan. The patient also complained about dysesthesia of the right thumb and index finger, fatigue and verbal disturbance. These cases appeared to be typical strokes in the acute phase, but after acute phase, they had dysethesia in the hand and periord for three months.

  • PDF

Study on the Evaluation of Renal Function According to Set a Partial Region of Interest in 99mTc-DMSA scan of the Pediatric Patient with a Duplicated Ureter (중복요관을 가진 소아환자의 99mTc-DMSA 검사에서 부분적 관심영역 설정에 따른 신기능 평가에 관한 연구)

  • Nam-Koong, Hyuk;Oh, Shin Hyun;Kim, Jung Yul;Choi, Yoon Jung;Kim, Jae Sam;Lee, Chang Ho
    • The Korean Journal of Nuclear Medicine Technology
    • /
    • v.17 no.1
    • /
    • pp.43-47
    • /
    • 2013
  • Purpose: A duplicated ureter is congenital renal malformations with ureter in two. Patients with duplicated ureter are in force to $^{99m}Tc-DMSA$ scan at surgery before and after. In existing examination, at produce result after $^{99m}Tc-DMSA$ scan, didn't compare to upper pole and lower pole with malformed kidney and compared to only relative uptake ratio. Therefore, this study will examine about utility of set a partial region of interest and to functional recovery of renal cell through change of upper pole uptake ratio of malformed kidney by setting each partial region of interest in upper pole and lower pole of malformed kidney in $^{99m}Tc-DMSA$ examination in surgery before and after. Materials and Methods: Pediatric patients with malformed kidney of incomplete duplicated ureter, 15 patients were enrolled in this study. Scanning were scan 3 to 4 hours after injection of $^{99m}Tc-DMSA$ 1.5 ~ 1.9 MBq/kg. Region of interest were each set in normal kidney, upper pole and lower pole with malformed kidney. Region of interest were set with same condition and method to images of surgery before and after that radio technologist 1 person, resident of nuclear medicine 1 person and doctor of urology together. Therefore, this study were compared to uptake ratio (A: B: C) that normal kidney (A), lower pole of malformed kidney (B) and upper pole of malformed kidney (C) about uptake ratio changes of malformed kidney in follow-up examination of surgery before and after. Results: When compared to 15 patients, uptake ratios were increased 7 persons and decreased 8 persons. Among increased 7 persons, it were periods of follow-up examination that 2 persons were 14 months, 4 persons were 12 months and 1 person was 8 months after surgery. Among decreased 8 persons, it were periods of follow-up examination that 4 persons were 12 months 3 persons were 6 months and 1 persons were 4 months after surgery. Conclusion: Existing study could not see the exact uptake ratio changes of malformed kidney because using only the overall Left-Right kidney uptake ratios. But a setting partial region of interest was able to see exactly what changes in the uptake of each upper pole and lower pole of malformed kidney. Because recovery of renal parenchymal cells is difficult in an evaluation of short period of time, follow-up examination should be made in long period of time. How to set up partial region of interest be thought that it would be useful.

  • PDF

Evaluation of Therapeutic Effect with Serum Thyroglobulin and Whole Body Scan after 200mCi $^{131}I$ Treatment in Patients with Well-Differentiated Thyroid Carcinoma (전이성 분화 갑상선암에서 200mCi 방사성 옥소 치료효과 평가를 위한 혈청 Thyroglobulin 추적검사와 전신스캔의 의의)

  • Lee, Chang-Hee;Yoon, Jong-Kil;Jeong, Sang-Hoon;Kwu, Gyo-Seon;Choi, Chang-Woon;Lim, Sang-Moo;Hong, Sung-Woon
    • The Korean Journal of Nuclear Medicine
    • /
    • v.29 no.4
    • /
    • pp.451-459
    • /
    • 1995
  • Thirty-eight patients with metastatic well-differentiated thyroid carcinoma treated with 200mCi $^{131}I$ were studied. There were false negative serum thyroglobulin values during TSH suppression or at anti-thyroglobulin antibody(+) and discrepancies between findings of whole body scan and serum thyroglobulin level. After one to five cycles of 200mCi $^{131}I$ therapy, complete remission and partial remission were achieved at 5.3% and 57.9%, respectively. We concluded that all of serum thyroglobulin, TSH, anti-thyroglobulin antibody, $^{131}I$ or $^{123}I$ whole body scan were necessary in follow up of metastatic well-differentiated thyroid carcinoma. Also, if there was no response after repetitive 200mCi $^{131}I$ therapy, higher doses of $^{131}I$ therapy should be considered.

  • PDF

Initial experience with intra-articular 188Re-tin colloid as a "radiation synovectomy" agent in various joints

  • Shinto, Ajit S;Indira, VU;Kamaleshwaran, KK;Banka, Vinay Kumar;Aswathy, KK;Thirumalaisamy, SG;Rajamani, V;Mallia, Madhav;Banerjee, Sharmila
    • Journal of Radiopharmaceuticals and Molecular Probes
    • /
    • v.1 no.2
    • /
    • pp.109-117
    • /
    • 2015
  • Radiation synovectomy has been proposed as a promising palliative therapy for recurrent joint effusions for the last two or three decades. Ionizing radiations emitted by intrarticularly administered radiolabelled colloids. The aim of this study was to assess the effectiveness of radiation synovectomy (RSV) using $^{188}Re$-tin colloid in the treatment of recurrent joint effusions and chronic synovitis of knee joints. Three phase bone scan was acquired for the concerned joint prior to radiosynovectomy. $^{188}Re$-tin colloid was prepared as per the reported protocol. 9 patients, diagnosed with rheumatoid arthritis and suffering from chronic resistant synovitis of the knee, ankle or elbow joints were administered the radiopharmaceuticals, checked for radiochemical purity >95% by intraarticular route. A whole body scan was acquired 2 h post-radiosynovectomy. In all the 9 treatments, no leakage to non-target organs was visible in the whole body scan. Static scans of the joint revealed complete retention of $^{188}Re$-tin colloid in the joints post administration of the agent. Clinically all patients exhibited a complete or partial response. RSV with $^{188}Re$-tin colloid was safe and effective in patients with chronic synovitis of rheumatoid origin.

Determination of Bar Code Cross-line Based on Block HOG Clustering (블록 HOG 군집화 기반의 1-D 바코드 크로스라인 결정)

  • Kim, Dong Wook
    • Journal of the Korea Institute of Information and Communication Engineering
    • /
    • v.26 no.7
    • /
    • pp.996-1003
    • /
    • 2022
  • In this paper, we present a new method for determining the scan line and range for vision-based 1-D barcode recognition. This is a study on how to detect valid barcode representative points and directions by applying the DBSCAN clustering method based on block HOG (histogram of gradient) and determine scan lines and barcode crosslines based on this. In this paper, the minimum and maximum search techniques were applied to determine the cross-line range of barcodes based on the obtained scan lines. This can be applied regardless of the barcode size. This technique enables barcode recognition even by detecting only a partial area of the barcode, and does not require rotation to read the code after detecting the barcode area. In addition, it is possible to detect barcodes of various sizes. Various experimental results are presented to evaluate the performance of the proposed technique in this paper.