• 대한기관식도과학회지
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• 제2권1호
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• pp.97-102
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• 1996

The larynx has three major functions such as protective reflex, respiration and phonation, and is richly innervated by sensory, sympathetic and parasympathetic nerves. The sensory innervation of the laryngeal mucosa, which is involved in the perception of pain, mechanical and chemical irritation, prtects the airway via various laryngeal reflexes. We studied the distribution of Substance P (SP) and Calcitonin Gene-Related Peptide (CGRP) sensory fibers in the rat's larynx using the immuno-histochemical methods. Many SP and CGRP immunoreactive fibers were found in all regions of the laryngeal mucosa except the vocal cords. SP immunoreactive fibers showed a very similar distribution to the CGRP fibers in the epithelium and submucosa. But SP immunoreactive fibers were sparser than CGRP immunoreactive fibers in distribution density. Both reactive fibers were denser in the supraglottic region than subglottic region. Especially, intraepithelial fibers displayed the densest innervation to the laryngeal surface of the epiglottis. h the subepithelium, SP and CGRP immunoreactive fibers were distributed along the wall of vessels and around the glands. The present results suggest that the regional distribution of SP and CGRP immunoreactivity may be responsible for the protective reflex function of the laryngeal inlet.

• 한방안이비인후피부과학회지
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• 제16권1호
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• pp.168-178
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• 2003

Strabismus refers to a extra-ocular muscle imbalance that results in improper alignment of the visual axes of two eyes. It may be divided into paralytic and non-paralytic strabismus. Paralytic strabismus is primarily a neurological problem: non-paralytic strabismus is more strictly an ophthalmologic problem. This case report focuses on paralytic strabismus resulting from palsies of the third and the sixth cranial nerves, respectively. Oculomotor nerve palsies result in binocular diplopia with characteristic patterns of strabismus. Oculomotor nerve provides motor and parasympathetic innervation to the eyes. Acquired oculomotor nerve palsies are not uncommon. Injury to the third nerve may result in complete or partial dysfunction. Complete third nerve palsy is manifested by ptosis, dilated pupil, an eye that is deviated down and out in primary position, and limited adduction, elevation, and depression. Patients with unilateral sixth nerve palsy complain of binocular, horizontal diplopia esotropia in the primary position due to unopposed action of the medial rectus and limitation of abduction due to weakness of the lateral rectus. Diplopia is worse in the direction of the paretic lateral rectus muscle. Paralytic strabismus are treated, based on the theory of Oriental medicine. with berbal medicines having gun-bi(健脾), bae-to(培土), gue-pung(祛風) effect of acupuncture around the eyes and etc. We describe a 63-year-old woman with complete the 3rd cranial nerve palsy and a 32-year-old woman with the unilateral 6th cranial nerve palsy who treated with acupuncture and herbal medicines and showed complete recovery.

• 대한통합의학회지
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• 제6권4호
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• pp.183-189
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• 2018

Purpose : As age increases, a low-level systemic inflammatory state develops and the levels of anti-aging hormones decrease. The vagus nerve activates parasympathetic nerves and promotes sulfation and secretion of neurotransmitter in the brain. Therefore, the purpose of this study was to investigate the effects of electrical vagus nerve stimulation on systemic inflammation (CRP) and anti-aging hormone (DHEA-S) levels in elder people. Methods : A total of 30 healthy elder people participated in this study, randomly divided into two groups of 15 subjects. Electrical vagus nerve stimulation was applied to the experimental group for 4 weeks. CRP and DHEA-S levels were compared with those of the control group. Results : The CRP level was significantly lower in the experimental group than in the control group. In the experimental group, there was a significant decrease in CRP before and after the intervention. However, the DHEA-S level was not significantly different between groups. Conclusion : Electrical vagus nerve stimulation may alleviate the low-level systemic inflammatory state found in elderly people. These results suggest that it may have the effect of reducing the degenerative inflammatory diseases of the elderly and delaying aging.

• 대한두개안면성형외과학회지
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• 제25권1호
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• pp.1-10
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• 2024

The facial nerve stimulates the muscles of facial expression and the parasympathetic nerves of the face. Consequently, facial nerve paralysis can lead to facial asymmetry, deformation, and functional impairment. Facial nerve palsy is most commonly idiopathic, as with Bell palsy, but it can also result from a tumor or trauma. In this article, we discuss traumatic facial nerve injury. To identify the cause of the injury, it is important to first determine its location. The location and extent of the damage inform the treatment method, with options including primary repair, nerve graft, cross-face nerve graft, nerve crossover, and muscle transfer. Intracranial proximal facial nerve injuries present a challenge to surgical approaches due to the complexity of the temporal bone. Surgical intervention in these cases requires a collaborative approach between neurosurgery and otolaryngology, and nerve repair or grafting is difficult. This article describes the treatment of peripheral facial nerve injury. Primary repair generally offers the best prognosis. If primary repair is not feasible within 6 months of injury, nerve grafting should be attempted, and if more than 12 months have elapsed, functional muscle transfer should be performed. If the affected nerve cannot be utilized at that time, the contralateral facial nerve, ipsilateral masseter nerve, or hypoglossal nerve can serve as the donor nerve. Other accompanying symptoms, such as lagophthalmos or midface ptosis, must also be considered for the successful treatment of facial nerve injury.

• 동의신경정신과학회지
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• 제20권2호
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• pp.85-99
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• 2009

Objectives : This study aimed to understand the influence of acupuncture on the human body by comparing changes within human bodies before and after people in normal health are treated with acupuncture at the acupoints HT7 and PC9, which are related to mental functions. Methods : The study was performed from January 3, 2008 to March 5, 2008 on 60 healthy males and females in their 20s. HRV, EEG, skin conductance response, respiration and peripheral skin temperature were measured for 5 minutes before acupuncture simulation was applied to the acupoints HT7 and PC9. During 20 minutes of acupuncture treatment, the same items were continuously measured to determine whether there had been any changes, and they were then measured for 5 minutes after the removal of the acupuncture needles in order to implement a comparative analysis. Results : 1. The HRV measurement showed that in the course of before, during and after acupuncture stimulation, heart rate, HF and HF norm decreased significantly (P<0.05) at HT7. LF, LF norm, and LF/HF ratio increased significantly (P>0.05), while heart rate, HF and HF norm decreased significantly (P<0.05) at PC9. 2. Skin conductance response increased significantly (P<0.05) at PC9 during and after the acupuncture simulation periods, compared with the pre acupuncture period. 3. the peripheral skin temperature increased significantly (P<0.05) both at HT7 and PC9 in the course of before, during and after acupuncture stimulation. 4. Compared with the pre-acupuncture period, respiration rate increased both at HT7 and at PC9 during and after the acupuncture simulation periods, but not in a statistically significance. 5. In the EEG measurement, when compared with the pre-acupuncture period at HT7, mid ${\beta}$ wave decreased significantly (P<0.05) during acupuncture treatment. Compared with the measurements during acupuncture treatment at PC9, low ${\beta}$ wave increased significantly (P<0.05) after the acupuncture needles were removed. Conclusions : When acupuncture treatment is applied at the acupoints HT7 and PC9, the activation of parasympathetic nerves decreases and the activation of sympathetic nerves increases in the HRV measurement. It was determined that PC9 makes the sympathetic nerves become highly activated in a skin conduction response. The effect of stability in the brain wave seemed to bo shown at HT7 than PC9.

• 한국자연치유학회지
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• 제7권2호
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• pp.39-46
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• 2018

교래자연휴양림을 탐방한 대상자들이 삼림욕을 한 후에 자율신경의 활성도에 미치는 영향을 평가하는 것이 목적이었다. 방법: 삼림욕 전후에 유비맥파기를 이용하여 맥파를 측정하였다. 결과: 삼림욕 후에 교감신경 활성(LF)의 변화에서는 대조군의 사전과 사후의 평균치 차이는 유의성이 없었으나, 실험군에서는 사전보다 사후에는 증가하여 유의성이 있었으며(p<.038), 분산분석에서는 그룹간(p<.014), 전후 차( p<.026) 및 그룹과 전후 차에서도 유의하였다(p<.018). 부교감신경 활성도(HF)의 변화에서는 대조군과 실험군 간에 모두 유의성이 없었다. LF/HF 비율에서는 실험군에서는 사전보다 사후에 증가하여 유의성이 있었고(p<.019), 그리고 분산분석에서는 그룹간, 사전 및 사후 차간에서도 유의성이 있었다(p<.04). 평균맥박의 변화에서는 대조군은 사전보다 사후에 유의성이 없이 감소하였으나, 실험군에서는 사전보다 사후에 증가하여 유의성이 있었다(p<.026). 맥박표준편차(SDNN)의 변화에서는 대조군 및 실험군의 사전보다 사후의 평균치는 감소하였으나 유의성이 없었으나, 분산분석에서는 그룹간에서는 유의성이 있었다(p <.014). 심박변이평균편차(RMSSD)의 변화에서는 대조군 및 실험군의 사전과 사후의 평균치 차이는 유의성이 없었다. 결론: 교래곶자왈 숲 삼림욕 후에는 자율신경의 활성이 변화되고 평균맥박도 높아져서 자연치유의 장소로 유용하다고 판단한다.

• 대한한방내과학회지
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• 제27권4호
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• pp.836-844
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• 2006

Background: Mahuang (Ephedra sinica STAPF) is well known as an herbal medicine and has been widely used to reduce body weight and increase athletic ability. However, as a result of reporting many cases of adverse effects on the cardiovascular system, use of dietary supplements containing ephedra was prohibited by the FDA. Objectives : The object of this study was to find the effectiveness of ephedra on weight loss without severe adverse effect. Methods : 16 healthy volunteers consisting of an ephedra group (N=8) and a placebo group (N=8) were investigated. Study form was a randomized, controlled, double-blind clinical trial. The ephedra group took 12g of ephedra while the placebo group took 12g of glutinous rice powder. Both groups were measured with BCA (body composition analysis) on weight loss and with HRV (heart rate variability) on its adverse effect before and after medication. Results : The following results were obtained after taking 12g of ephedra for 14 days. In the ephedra group, body weight reduced significantly. In the placebo group, there were no significant differences of body weight between before and after placebo treatment. There was a slight increase of heart beat rate and deactivation of cardiac activity. Parasympathetic nerves were deactivated, but balances of autonomic nervous system were well maintained. Conclusions : The results suggest that ephedra in healthy adults tends to reduce body weight and deactivation of autonomic nervous system and cardiac activity.

• The Korean Journal of Pain
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• 제35권3호
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• pp.250-260
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• 2022

Background: Cranial nerve ganglia, which are prone to viral infections and tumors, are located deep in the head, so their detailed anatomy is difficult to understand using conventional cadaver dissection. For locating the small ganglia in medical images, their sectional anatomy should be learned by medical students and doctors. The purpose of this study is to elucidate cranial ganglia anatomy using sectioned images and three-dimensional (3D) models of a cadaver. Methods: One thousand two hundred and forty-six sectioned images of a male cadaver were examined to identify the cranial nerve ganglia. Using the real color sectioned images, real color volume model having a voxel size of 0.4 × 0.4 × 0.4 mm was produced. Results: The sectioned images and 3D models can be downloaded for free from a webpage, anatomy.dongguk.ac.kr/ganglia. On the images and model, all the cranial nerve ganglia and their whole course were identified. In case of the facial nerve, the geniculate, pterygopalatine, and submandibular ganglia were clearly identified. In case of the glossopharyngeal nerve, the superior, inferior, and otic ganglia were found. Thanks to the high resolution and real color of the sectioned images and volume models, detailed observation of the ganglia was possible. Since the volume models can be cut both in orthogonal planes and oblique planes, advanced sectional anatomy of the ganglia can be explained concretely. Conclusions: The sectioned images and 3D models will be helpful resources for understanding cranial nerve ganglia anatomy, for performing related surgical procedures.

• 한국환경과학회지
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• 제31권3호
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• pp.219-226
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• 2022

This study was conducted to investigate the response of the human body to stress induced by wall recording of subway stations in the city center. The experiment was conducted as a simulation exercise, and six images were selected and produced based on Subway Line 2, a representative underground space in Seoul. The study participants included 24 male and female college students. A three-minute experiment was conducted, during which the participants were shown the control image and green wall image once each. To measure psychological status, the following measurement indicators were used: Semantic Differential, Positive Affect and Negative Affect Schedule and State-Trait Anxiety Inventory. Physiological changes were investigated by tracking participants' heart rate and blood pressure. Results showed that parasympathetic and sympathetic nerves were activated in the presence of the green wall in the subway station. The psychological evaluation analysis revealed that negative affect toward underground space decreased, while positive affect increased. This study found that the green wall in subway stations has a stable effect on the human body, both psychologically and physiologically. In the future, green walls in underground spaces can be used to reduce psychological stress and increase physiological relaxation.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2007년도 추계종합학술대회
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• pp.170-174
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• 2007

뇌파에 관한 연구는 의학 및 공학 분야에서 많이 활성화 되어 있지만, 침구학에서의 뇌파분석에 과한 연구는 아직 많이 이루어져야 할 부분 중 하나이다. 그러므로 본 연구는 침구요법 중 간접 뜸 자극에 의한 뇌파를 분석하고 자율신경계와의 상관관계를 분석을 하고자 한다. 본 연구의 실험은 간접 쑥 뜸을 인체의 중완, 신궐, 관원의 경혈 점에 자극하고, 자극 전, 자극 중, 자극 후 1시간, 그리고 자극 후 2시간 일 때의 뇌파를 측정한다. 그리고 측정된 데이타는 Matlab 7.0을 이용하여 FFT 및 주파수 파워 스펙트럼을 적용하여 ${\alpha}$, ${\beta}$, ${\delta}$, ${\theta}$파 성분을 자극 단계별로 나누어 주파수 각 성분 비율의 변화, 그리고 진폭의 크기변화량에 대하여 분석 고찰하였다. 본 연구의 결과, EEG 데이터를 FFT를 적용하여 ${\alpha}$, ${\beta}$, ${\delta}$, ${\theta}$파의 비율을 분석한 결과 ${\alpha}$파가 자극 전보다 자극 후 약 2배 정도 증가하는 것을 알 수 있었다. 그리고 전체의 파워스펙트럼 분석에서 ${\alpha}$파, ${\beta}$파의 에너지가 전체적으로 감소하므로 부교감신경이 활성화됨을 알 수 있었다. 본 연구와 기존 연구의 결과를 비교해 보면, 간접 뜸 자극은 자율신경계의 변화에 영향을 줄 수 있으며 ${\alpha}$파의 비율적 증가로 긴장 상태나 스트레스 상태의 사람에게 안정을 가져다 줄 수 있음을 확인 할 수 있었다.