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http://dx.doi.org/10.15268/ksim.2018.6.4.183

Effect of Electrical Vagus Nerve Stimulation to Control Systemic Inflammation and Anti-Aging Hormone on Elder  

Moon, Hyunju (Vagus Nerve Research Center, Director of the Center)
Goo, Bongoh (Dept. of Physical Therapy, Catholic University of Pusan)
Publication Information
Journal of The Korean Society of Integrative Medicine / v.6, no.4, 2018 , pp. 183-189 More about this Journal
Abstract
Purpose : As age increases, a low-level systemic inflammatory state develops and the levels of anti-aging hormones decrease. The vagus nerve activates parasympathetic nerves and promotes sulfation and secretion of neurotransmitter in the brain. Therefore, the purpose of this study was to investigate the effects of electrical vagus nerve stimulation on systemic inflammation (CRP) and anti-aging hormone (DHEA-S) levels in elder people. Methods : A total of 30 healthy elder people participated in this study, randomly divided into two groups of 15 subjects. Electrical vagus nerve stimulation was applied to the experimental group for 4 weeks. CRP and DHEA-S levels were compared with those of the control group. Results : The CRP level was significantly lower in the experimental group than in the control group. In the experimental group, there was a significant decrease in CRP before and after the intervention. However, the DHEA-S level was not significantly different between groups. Conclusion : Electrical vagus nerve stimulation may alleviate the low-level systemic inflammatory state found in elderly people. These results suggest that it may have the effect of reducing the degenerative inflammatory diseases of the elderly and delaying aging.
Keywords
electrical vagus nerve stimulation; CRP; DHEA-S; elder;
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