• Title/Summary/Keyword: Parameters Sensitivity

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Self-Consistent Calculation of Electronic Subband Structure at GaInAs/InP Heterojunction (Self-Consistent 방법에 의한 GaInAs/InP 이종접합에서의 전자 부밴드 구조계산)

  • Kong, Joon-Jin;Park, Seong-Ho;Kim, Choon-Won;Han, Baik-Hyung;,
    • Journal of the Korean Institute of Telematics and Electronics
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    • v.26 no.1
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    • pp.38-47
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    • 1989
  • Calculated results for subband structures of electrons in GaInAs/InP hegerojunctions are presented, and their sensitivity to two parameters background impurity concentrations in the GaInAs, heterojunction barrier height-is examined. Energy levels, Fermi level and population of the ground energy level are increased with background impurity concentrations. The difference of the ground and first-excited energy levels is also increased with the increase of barrier height. However, the difference of the energy levels is almost invariable with barier height. But, population of the ground energy level decreases, but that of the first-excited energy level shows a slight increase.

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A $^{13}CO(1-0)$ Survey of the Second Quadrant of Galactic Plane I (은하면 제2상한 $^{13}CO(1-0)$ 탐사관측연구 I)

  • Lee, Young-Ung;Kim, Young-Sik;Kang, Hyun-Woo;Jung, Jae-Hoon;Lee, Chang-Hoon;Yim, In-Sung;Kim, Bong-Gyu;Kim, Hyun-Goo;Kim, Kwang-Tae
    • The Bulletin of The Korean Astronomical Society
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    • v.37 no.1
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    • pp.75.1-75.1
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    • 2012
  • We have observed the part of the second quadrant of the Galactic Plane in $^{13}CO(1-0)$ using the multibeam receiver system installed on the 14 m telescope at Taeduk Radio Astronomy Observatory. The target region (L=108 to 112.5) is the part of the $^{12}CO$ Outer Galactic Plane Survey (Heyer et al. 1998), and it is for the exact Galactic plane with the latitude range of +1 and -1 degree. Total of 48,000 spectra (about 9 square degees) were obtained on 50" grid. The selected velocity resolution is 0.63 km/sec and sensitivity per channel is 0.17 K, and the covered velocity is 320 km/sec. We developed a new reduction method, which effectively deals with a relatively noisy 3-dimensional database. The collected $^{13}CO$ database will be manipulated with pre-existing $^{12}CO$ data to get several physical parameters. As it is located in the second quadrant, the kinematic distances of the individual clouds, which will be identified, can be estimated relatively easily without any distance ambiguity. In this meeting we present the reduction method, statistics, and some channel maps, integrated intensity maps, and spatial-velocity maps. We intend to clarify any difference of their characteristics between the clouds in the Outer Galaxy and Inner Galaxy using our data base.

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MOTION DESIGN OPTIMIZATION OF AUV DOUBLE HYDROFOIL FOR IMPROVEMENT OF THRUST AND EFFICIENCY (추력과 효율 향상을 위한 AUV Double Hydrofoil의 모션 최적설계)

  • So, H.K.;Jo, T.H.;Lee, Y.H.;Kim, J.S.;Han, J.H.;Koo, B.C.;Lee, D.H.
    • Journal of computational fluids engineering
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    • v.21 no.1
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    • pp.78-85
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    • 2016
  • While most AUV researches have concerned about single hydrofoil, practical AUV's are generally operated with multiple hydrofoils. Double hydrofoil study attempts to evaluate thrust and efficiency with various flapping motions, and carries out design optimization using parametric analysis. Flow patterns such as vortex shedding and wake-body interaction are carefully investigated during design variable sensitivity analysis. The purpose of this design optimization is to find out the optimal motion that yields maximum thrust and efficiency. The design optimization employes several techniques such as table of orthogonal arrays, Kriging method, ANOVA analysis and MGA. Throughout this research, it is possible to find the optimal values of heaving ratio, heaving shift and pitch shift: Heaving ratio 0.950, heaving shift $23.120^{\circ}$ and pitch shift $89.991^{\circ}$ are found to be optimal values in double hydrofoil motions. Thrust and efficiency are 16.7% and 35.1% higher than existing AUV that did not consider nonlinear dependency of motion parameters. This results may offer an effective framework that is applicable to various AUV motion analyses and designs.

A Three-Dimensional Numerical Model of Hydrodynamic Flow on σ-Coordinate (연직변환좌표(鉛直變換座標)에서 3차원(次元) 유동(流動) 수직모형(數値模型))

  • Jung, Tae Sung;Lee, Kil Seong
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.14 no.5
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    • pp.1145-1158
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    • 1994
  • A three-dimensional, finite difference, numerical model with free surface was developed on ${\sigma}$-coordinate. A semi-implicit numerical scheme in time has been adopted for computational efficiency. The scheme is essentially independent of the stringent stability criteria (CFL condition) for explicit schemes of external surface gravity wave. Implicit algorithm was applied for vertical shear stress, Coriolis force and pressure gradient terms. The reliability of the model with vertically variable grid system was checked by the comparison of simulation results with analytic solution of wind-driven currents in a one-dimensional channel. Sensitivity analysis of differencing parameters was carried out by applying the model to the calculation of wind-driven currents in a square lake.

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Calibration of QUAL2E Reaction Coefficients by the Influence Coefficient Algorithm (영향계수(影響係數)를 이용한 QUAL2E 모형의 반응계수(反應係數) 추정(推定))

  • Jun, Kyung Soo;Lee, Kil Seong
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.13 no.4
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    • pp.163-176
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    • 1993
  • A methodology based on the influence coefficient algorithm was established for the optimal calibration of QUAL2E reaction coefficients. It was applied to the stream sections from the Chungju Dam to the downstream end of the South Han River. A water budget analysis using the monthly records of reservoir inflows and outflows in 1990 was made to determine tributary inflows. Estimated tributary inflows were used, together with the monthly records of water quality measurements in 1990, for the calibration of reaction coefficients. Simulated quality constituents were chl.a. nitrogen cycles, phosphorus cycles. BOD and DO. A sensitivity analysis was made to determine significant reaction coefficients, and as a result 11 reaction coefficients were selected as calibration parameters. The influence coefficient algorithm applied to the calibration of QUAL2E reaction coefficients proved to be a useful one yielding a rapid convergence. Each calibration parameter converged to an optimum value within 3 iterations.

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Study of Ultrasonic Nonlinearity in Heat-Treated Material (열처리된 재료의 초음파 비선형성에 관한 연구)

  • Li, Weibin;Lee, Jae-Sun;Cho, Youn-Ho
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.34 no.6
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    • pp.751-756
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    • 2010
  • Ultrasonic nonlinearity is very sensitive to changes in material properties. This paper describes the study of the correlation between heat treatment and ultrasonic nonlinearity by taking nonlinear factors into consideration. A modified formula was proposed for ultrasonic velocity. This formula indicated that the changes occurring in nonlinearity during heat treatments cause changes in the ultrasonic velocity. The experimental results show that the relative nonlinearity parameters calculated from the modified ultrasonic velocities and the ratio of amplitudes of the second harmonic and fundamental wave are in good agreement. The experimental results prove that heat treatment can result in changes in material nonlinearity. Moreover, the relative nonlinearity parameter calculated from the modified velocity formula is has a large value. Since this parameter has high sensitivity to changes in nonlinearity, it can be used to represent the relative nonlinearity change calculated in this study by using the modified formula for ultrasonic velocity.

Drug resistance of bladder cancer cells through activation of ABCG2 by FOXM1

  • Roh, Yun-Gil;Mun, Mi-Hye;Jeong, Mi-So;Kim, Won-Tae;Lee, Se-Ra;Chung, Jin-Woong;Kim, Seung Il;Kim, Tae Nam;Nam, Jong Kil;Leem, Sun-Hee
    • BMB Reports
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    • v.51 no.2
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    • pp.98-103
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    • 2018
  • Recurrence is a serious problem in patients with bladder cancer. The hypothesis for recurrence was that the proliferation of drug-resistant cells was reported, and this study focused on drug resistance due to drug efflux. Previous studies have identified FOXM1 as the key gene for recurrence. We found that FOXM1 inhibition decreased drug efflux activity and increased sensitivity to Doxorubicin. Therefore, we examined whether the expression of ABC transporter gene related to drug efflux is regulated by FOXM1. As a result, ABCG2, one of the genes involved in drug efflux, has been identified as a new target for FOXM1. We also demonstrated direct transcriptional regulation of ABCG2 by FOXM1 using ChIP assay. Consequently, in the presence of the drug, FOXM1 is proposed to directly activate ABCG2 to increase the drug efflux activation and drug resistance, thereby involving chemoresistance of bladder cancer cells. Therefore, we suggest that FOXM1 and ABCG2 may be useful targets and important parameters in the treatment of bladder cancer.

Numerical Simulation of the Coalescence of Air Bubbles in Turbulent Shear Flow: 2. Model Application (난류전단 흐름에서의 기포응집에 관한 수치모의: 2. 모형의 적용)

  • Jun, Kyung Soo;Jain, Subhash C.
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.14 no.6
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    • pp.1365-1373
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    • 1994
  • A Monte-Carlo simulation model, developed to predict size distribution of air bubbles in turbulent shear flow, is applied to a laboratory-scale problem. Sensitivity to various numerical and physical parameters of the model is analyzed. Practical applicability of the model is explored through comparisons of results with experimental measurements. Bubble size increases with air-water discharge ratio and friction factor. Bubble size decreases with increasing mean flow velocity, but the total bubble surface area in the aeration region remains fairly constant. The effect on bubble size distribution of the longitudinal length increment in the simulation model is negligible. A larger radial length increment yields more small and large bubbles and fewer in between. Bubble size distribution is significantly affected by its initial distribution and the location of air injection. Collision efficiency is introduced to explain the discrepancy between collisions with and without coalescence.

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A Design and Manufacturing of Two Types of Micro-grippers using Piezoelectric Actuators for the Micromanipulation (미세 조작을 위한 압전 구동 집게의 설계 및 제작)

  • 박종규;문원규
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2003.06a
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    • pp.246-250
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    • 2003
  • In this study, two new types of micro-grippers in which micro-fingers are actuated by piezoelectric multi-layer benders and stacks are introduced for the manipulation of micrometer-sized objects. First, we constructed a 3-chopstick-mechanism tungsten gripper, which is composed of three chopsticks: two are designed to grip micro-objects, and tile third is used to help grasp and release the objects through overcoming especially electrostatic force among some surface effects including electrostatic, van der Waals forces and surface tension. Second, a 2-chopstick-mechanism silicon micro-gripper that uses an integrated force sensor to control the gripping force was developed. The micro-gripper is composed of a piezoelectric multilayer bender for actuating the gripper fingers, silicon fingertips fabricated by use of silicon-based micromachining, and supplementary supports. The micro-gripper is referred to as a hybrid-type micro-gripper because it is composed of two main components; micro-fingertips fabricated using micromachining technology to integrate a very sensitive force sensor for measuring the gripping force, and piezoelectric gripper finger actuators that are capable of large gripping forces and moving strokes. The gripping force signal was found to have a sensitivity of 667 N/V. To the design of each of components of both of the grippers. a systematic design approach was applied, which made it possible to establish the functional requirements and design parameters of the micro-grippers. The micro-grippers were installed on a manual manipulator to assess its performance in tasks such as moving micro-objects from one position to a desired position. The experiment showed that the micro-grippers function effectively.

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Dynamic Analysis of Design Data for Structural Lap Joint (LAP 구조물 결합부의 설계치 확보를 위한 동역학적 해석)

  • 윤성호
    • Journal of KSNVE
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    • v.8 no.1
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    • pp.57-74
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    • 1998
  • This paper is concerned with a combination of experimental and analytical investigation aimed at identifying modeling errors, accounted for the lack of correlation between experimental measurements and analytical predictions of the modal parameters for lap joint panels. A nonlinearity vibration test methodology, initiated from the theoretical analysis, is suggested for measurements of dynamic stiffnesses in a lap joint using the rivet fastener. Based on the experimental evidence on discrepancies between measured and predicted frequencies, improved finite element models of the joint are developed using PATRAN and ABAQUS, in which the beam element size is evaluated from the joint stiffnesses readily determined in the test. The beam element diameter as a principal design parameter is tuned to match experimental results within the evaluated bound value. Frequencies predicted by the proposed numerical model are compared with frequencies measured by the test. Improved predictions based on this new model are observed when compared with those based on conventional modeling practices.

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