• Journal of the Computational Structural Engineering Institute of Korea
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• v.13 no.4
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• pp.405-415
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• 2000

Time series of wind-induced pressure on a structure are modeled using autoregressive moving average (ARMA) model. In an AR process, the current value of the time series is expressed in terms of a finite, linear combination of the previous values and a white noise. In a MA process, the value of the time series is linearly dependent on a finite number of the previous white noises. The ARMA process is a combination of the AR and MA processes. In this paper, the ARMA models with several different combinations of the AR and MA orders are fitted to the wind-induced pressure time series, and the procedure to select the most appropriate ARMA model to represent the data is described. The maximum likelihood method is used to estimate the model parameters, and the AICC model selection criterion is employed in the optimization of the model order, which is assumed to be a measure of the temporal complexity of the pressure time series. The goodness of fit of the model is examined using the LBP test. It is shown that AR processes adequately fit wind pressure time series.

• Journal of Microbiology and Biotechnology
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• v.24 no.4
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• pp.497-506
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• 2014

In this study, crude glycerol was used as a carbon source in the cultivation of wild yeasts, aiming at the production of microbial lipids and citric acid. Forty yeasts of different sources were tested concerning their growth in crude and commercial glycerol. Four yeasts (Lindnera saturnus UFLA CES-Y677, Yarrowia lipolytica UFLA CM-Y9.4, Rhodotorula glutinis NCYC 2439, and Cryptococcus curvatus NCYC 476) were then selected owing to their ability to grow in pure ($OD_{600}$ 2.133, 1.633, 2.055, and 2.049, respectively) and crude ($OD_{600}$ 2.354, 1.753, 2.316, and 2.281, respectively) glycerol (10%, 20%, and 30%). Y. lipolytica UFLA CM-Y9.4 was selected for its ability to maintain cell viability in concentrations of 30% of crude glycerol, and high glycerol intake (18.907 g/l). This yeast was submitted to lipid production in 30 g/l of crude glycerol, and therefore obtained 63.4% of microbial lipids. In the fatty acid profile, there was a predominance of stearic (C18:0) and palmitic (C16:0) acids in the concentrations of 87.64% and 74.67%, respectively. We also performed optimization of the parameters for the production of citric acid, which yielded a production of 0.19 g/l of citric acid in optimum conditions (38.4 g/l of crude glycerol, agitation of 184 rpm, and temperature of $30^{\circ}C$). Yarrowia lipolytica UFLA CM-Y9.4 presented good lipid production when in the concentration of 30 g/l of glycerol. These data may be used for production in large quantities for the application of industrial biodiesel.

• Journal of Microbiology and Biotechnology
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• v.23 no.3
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• pp.364-374
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• 2013

Monacolin K and yellow pigment, produced by Monascus sp., have each been proven to be beneficial compounds as antihypercholesterolemic and anti-inflammation agents, respectively. However, citrinin, a human toxic substance, was also synthesized in this fungus. In this research, solidstate fermentation of M. purpureus TISTR 3541 was optimized by statistical methodology to obtain a high production of monacolin K and yellow pigment along with a low level of citrinin. Fractional factorial design was applied in this study to identify the significant factors. Among the 13 variables, five parameters (i.e., glycerol, methionine, sodium nitrate, cultivation time, and temperature) influencing monacolin K, yellow pigment, and citrinin production were identified. A central composite design was further employed to investigate the optimum level of these five factors. The maximum production of monacolin K and yellow pigment of 5,900 mg/kg and 1,700 units/g, respectively, and the minimum citrinin concentration of 0.26 mg/kg were achieved in the medium containing 2% glycerol, 0.14% methionine, and 0.01% sodium nitrate at $25^{\circ}C$ for 16 days of cultivation. The yields of monacolin K and yellow pigment were about 3 and 1.5 times higher than the basal medium, respectively, whereas citrinin was dramatically reduced by 36 times.

• Journal of Microbiology and Biotechnology
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• v.23 no.3
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• pp.343-350
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• 2013

(R)-[3,5-Bis(trifluoromethyl)phenyl] ethanol is a key chiral intermediate for the synthesis of aprepitant. In this paper, an efficient synthetic process for (R)-[3,5- bis(trifluoromethyl)phenyl] ethanol was developed via the asymmetric reduction of 3,5-bis(trifluoromethyl) acetophenone, catalyzed by Leifsonia xyli CCTCC M 2010241 cells using isopropanol as the co-substrate for cofactor recycling. Firstly, the substrate and product solubility and cell membrane permeability of biocatalysts were evaluated with different co-substrate additions into the reaction system, in which isopropanol manifested as the best hydrogen donor of coupled NADH regeneration during the bioreduction of 3,5-bis(trifluoromethyl) acetophenone. Subsequently, the optimization of parameters for the bioreduction were undertaken to improve the effectiveness of the process. The determined efficient reaction system contained 200mM of 3,5-bis(trifluoromethyl) acetophenone, 20% (v/v) of isopropanol, and 300 g/l of wet cells. The bioreduction was executed at $30^{\circ}C$ and 200 rpm for 30 h, and 91.8% of product yield with 99.9% of enantiometric excess (e.e.) was obtained. The established bioreduction reaction system could tolerate higher substrate concentrations of 3,5- bis(trifluoromethyl) acetophenone, and afforded a satisfactory yield and excellent product e.e. for the desired (R)-chiral alcohol, thus providing an alternative to the chemical synthesis of (R)-[3,5-bis(trifluoromethyl)phenyl] ethanol.

• Journal of Microbiology and Biotechnology
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• v.30 no.11
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• pp.1785-1791
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• 2020

In a previous study, the sequential optimization and regulation of environmental parameters using the PhotoBiobox were demonstrated with high-throughput screening tests. In this study, we estimated changes in the biovolume-based composition of a polyculture built in vitro and composed of three algal strains: Chlorella sp., Scenedesmus sp., and Parachlorella sp. We performed this work using the PhotoBiobox under different temperatures (10-36℃) and light intensities (50-700 μmol m^-2 s^-1) in air and in 5% CO₂. In 5% CO₂, Chlorella sp. exhibited better adaptation to high temperatures than in air conditions. Pearson's correlation analysis showed that the composition of Parachlorella sp. was highly related to temperature whereas Chlorella sp. and Scenedesmus sp. showed negative correlations in both air and 5% CO₂. Furthermore, light intensity slightly affected the composition of Scenedesmus sp., whereas no significant effect was observed in other species. Based on these results, it is speculated that temperature is an important factor in influencing changes in algal polyculture community structure (PCS). These results further confirm that the PhotoBiobox is a convenient and available tool for performance of lab-scale experiments on PCS changes. The application of the PhotoBiobox in PCS studies will provide new insight into polyculture-based ecology.

• Journal of the Korean Institute of Intelligent Systems
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• v.6 no.2
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• pp.81-89
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• 1996

A design method of fuzzy modeling is presented for the model identification of route choice of traffic problems.The proposed fuzzy modeling implements system structure and parameter identification in the eficient form of""IF..., THEN-.."", using the theories of optimization theory, linguistic fuzzy implication rules. Three kinds ofmethod for fuzzy modeling presented in this paper include simplified inference (type I), linear inference (type 21,and proposed modified-linear inference (type 3). The fuzzy inference method are utilized to develop the routechoice model in terms of accurate estimation and precise description of human travel behavior. In order to identifypremise structure and parameter of fuzzy implication rules, improved complex method is used and the least squaremethod is utilized for the identification of optimum consequence parameters. Data for route choice of trafficproblems are used to evaluate the performance of the proposed fuzzy modeling. The results show that the proposedmethod can produce the fuzzy model with higher accuracy than previous other studies -BL(binary logic) model,B(production system) model, FL(fuzzy logic) model, NN(neura1 network) model, and FNNs (fuzzy-neuralnetworks) model -.fuzzy-neural networks) model -.

• Journal of the Korean Society for Railway
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• v.15 no.2
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• pp.135-140
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• 2012

Interior Permanent Magnet Synchronous motors (IPMSM) with concentrated winding are superior to distributed winding in the power density point of view. But it causes huge amount of eddy current losses on the permanent magnet. This paper presents the optimal permanent magnet V-shape on the rotor of an interior permanent magnet synchronous motor to reduce the core losses and improve the performance. Each eddy current loss on permanent magnet has been investigated in detail by using FEM (Finite Element Method) instead of equivalent magnetic circuit network method in order to consider saturation and non-linear magnetic property. Simulation-based design of experiment is also applied to avoid large number of analyses according to each design parameter and consider expected interactions among parameters. Consequently, the optimal design to reduce the core loss on the permanent magnet while maintaining or improving motor performance is proposed by an optimization algorithm using regression equation derived and lastly, it is verified by FEM.

• Journal of the Earthquake Engineering Society of Korea
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• v.9 no.2 s.42
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• pp.17-27
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• 2005

This paper presents an integrated optimum design and a cost effectiveness evaluation method of a viscoelastically damped structural system. The criterion selected for the optimization is the minimization of the life?cycle cost which is a function of structural sizing variables and the amount of the viscoelastic damper. A genetic algorithm is used as a numerical searching technique in order to simultaneously find the optimum parameters of the integrated system. Optimal distributions of design variables according to various seismic characteristics are investigated by applying the proposed design method to a numerical example of a 10?story building structure. The cost effectiveness of viscoelastically damped structural system is also evaluated by comparing the life-cycle cost of the structure without viscoelastic dampers. The results show that the viscoelastic damper is effective in a region of low to moderate seismicity.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.43 no.5 s.347
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• pp.17-24
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• 2006

The optical feedforward is known as a complicated technique in spite of its superior linearization. Here we optimized the feedforward circuit parameters using a systematic approach for optimum efficiency. A systematic approach was verified by transmission experiments of 2.14 GHz two tones. The compared third order IMD was enhanced by 38 dB for two-tone case. The experimental results for transmission of W-CDMA signals were described. The ACPR was enhanced by 20 dB for 1 W-CDMA carrier and by 16 dB for 3 W-CDMA carriers. Also, noise level was reduced by 7 dB.

• Journal of the Institute of Electronics and Information Engineers
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• v.51 no.12
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• pp.174-179
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• 2014

In this study, we measure the radiation dose for every experiments performed during the training education in radiologic science and estimate the radiation dose to each participant in the training education to propose a safe curriculum including operation of the training education. In this paper, we optimized the three parameters and the results show the dramatically reduced radiation dose to each participant. The proposed arrangement of the subjects and operation of the training education will be very helpful to reorganize the curriculum and the subject operation and will protect the students from the radiation dose.