• Biomedical Science Letters
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• v.10 no.4
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• pp.507-514
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• 2004

The Pseudomonas aeruginosa isolated from the clinical specimens has a mutation on the QRDR (quinolone resistance determining region). There were obvious mutations in both gyrA and parC gene which are major targets of quinolone. Simultaneous mutations were found two sites or more on these genes in all of ten strains. GyrB or parE gene had only silent mutation without converted amino acids. We confirmed that P. aeruginosa from clinical specimens exhibited decreased sensitivity to fluroquiolone due to changed Thr-83→lle and Asp-87→Asn types on gyrA and altered Ser-87→Leu type on parC. This is the first finding that a new Met-93→Thr type on parC as well as mutations on gyrB or parE genes differed from existing patterns. This study showed more mutations of gyrA rather than parC, suggesting that change of Type Ⅳ topoisomerase is more serious than that of type Ⅱ (DNA gyrase).

• The Journal of Korean Institute of Communications and Information Sciences
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• v.24 no.6A
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• pp.845-854
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• 1999

In the reverse link of DS/CDMA systems, the Peak-to-Average Ratio(PAR) performance can be analyzed by phase variations of spread signals. In the paper, we propose s PAR analysis method using phase variations of signals. Using this method, we analyze the PAR performances of existing spreading methods and suggest several methods improving the PAR performances. Also we show the proposed methods have negligible BER degradation compared to the existing ones.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.29 no.12
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• pp.824-828
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• 2016

In this study, effects of ICP (inductively coupled plasma) treatment on PAR thin film have been investigated. A maximum etch rate of the PAR thin films and the selectivity of PAR to PR were obtained as 110 nm/minand 1.1 in the $CF_4/O_2$ (5:15 sccm) gas mixture. We present the surface properties of PAR thin film with various treatment conditions. The surface morphology and cross section of the PAR thin film was observed by AFM (atomic force microscopy) and FE-SEM (filed emission scanning electron microscopy).

• The Journal of Korean Institute of Communications and Information Sciences
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• v.30 no.4C
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• pp.230-238
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• 2005

An orthogonal frequency division multiplexing (OFDM) system consists of a number of independently modulated subcarriers and, thus, a high peak-to-average power ratio (PAR) can occur when the subcarriers are added coherently. The high PAR brings such disadvantages as an increased complexity of the analog-to-digital (ADC) and digital-to-analog (DAC) converters and a reduced efficiency of the radio frequency (RF) power amplifier. In this paper, we propose a novel PAR reduction scheme called selective mapping of partial tones (SMOPT). The SMOPT scheme has a reduced complexity, lower sensitivity to peak reduction tones (PRT) positions, and a shorter processing time as compared with the conventional tone reservation (TR) scheme. The performance of the SMOPT scheme is analyzed based on the IEEE 802.1la wireless local area network(WLAM) physical layer model. Numerical results show that the SMOPT scheme outperforms the TR scheme under various scenarios.

• The Korean Journal of Physiology and Pharmacology
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• v.18 no.6
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• pp.489-495
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• 2014

Protease-activated receptor (PAR)-2 is expressed in endothelial cells and vascular smooth muscle cells. It plays a crucial role in regulating blood pressure via the modulation of peripheral vascular tone. Although some reports have suggested involvement of a neurogenic mechanism in PAR-2-induced hypotension, the accurate mechanism remains to be elucidated. To examine this possibility, we investigated the effect of PAR-2 activation on smooth muscle contraction evoked by electrical field stimulation (EFS) in the superior mesenteric artery. In the present study, PAR-2 agonists suppressed neurogenic contractions evoked by EFS in endothelium-denuded superior mesenteric arterial strips but did not affect contraction elicited by the external application of noradrenaline (NA). However, thrombin, a potent PAR-1 agonist, had no effect on EFS-evoked contraction. Additionally, ${\omega}$-conotoxin GVIA (CgTx), a selective N-type $Ca^{2+}$ channel ($I_{Ca-N}$) blocker, significantly inhibited EFS-evoked contraction, and this blockade almost completely occluded the suppression of EFS-evoked contraction by PAR-2 agonists. Finally, PAR-2 agonists suppressed the EFS-evoked overflow of NA in endothelium-denuded rat superior mesenteric arterial strips and this suppression was nearly completely occluded by ${\omega}$-CgTx. These results suggest that activation of PAR-2 may suppress peripheral sympathetic outflow by modulating activity of $I_{Ca-N}$ which are located in peripheral sympathetic nerve terminals, which results in PAR-2-induced hypotension.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.30 no.12C
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• pp.1181-1185
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• 2005

A combining of MIMO signal processing with OFDM is regarded as a promising solution of enhancing the performance of next generation wireless system. Therefore, in this paper, an OFDM-based wireless system employing layered space-time architecture is considered for a high-rate transmission. In the MIMO-OFDM system, we evaluate the PAR performance using the SLM approaches. The investigated SLM scheme for MIMO-OFDM signals selects the transmitted sequence with lowest average PAR over all transmitting antennas and retrieves the side information very accurately at the expense of a slight degradation of the PAR performance. The low probability of false side information can improve the overall detection performance of the MIMO-OFDM system with erroneous side information compared to the ordinary SLM approache, respectively. Also, we provide closed form of the average BER performance in MIMO-OFDM system using analytic approach.

• Ocean Science Journal
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• v.41 no.4
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• pp.235-244
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• 2006

Determining 'photosynthetically active radiation' (PAR) is a key part of calculating phytoplankton productivity in a biogeochemical model. We explore the daily and seasonal variability in the ratio of PAR irradiance to total irradiance that occurred at Ieodo Ocean Research Station (IORS) in the East China Sea under clear-sky conditions in 2004 using a simple radiative transfer model (RTM). Meteorological data observed at IORS and aerosol optical properties derived from Aerosol Robotic Network observations at Gosan are used for the RTM. Preliminary results suggest that the use of simple PAR irradiance-ratio values is appropriate in calculating phytoplankton productivity as follows: an average of $0.44\;({\pm}0.01)$ in January to an average of $0.48\;({\pm}0.01)$ in July, with average daily variabilities over these periods of about $0.016\;({\pm}0.008)$ and $0.025\;({\pm}0.008)$, respectively. The model experiments demonstrate that variations in the major controlling input parameters (i.e. solar zenith angle, precipitable water vapor and aerosol optical thickness) cause PAR irradiance ratio variation at daily and seasonal timescales. Further, increases (>0.012) in the PAR irradiance ratio just below the sea-surface are positively correlated with high solar zenith angles and strong wind stresses relative to those just above the sea-surface.

• Molecules and Cells
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• v.37 no.1
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• pp.9-16
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• 2014

ADP-ribosylation is a type of posttranslational modification catalyzed by members of the poly(ADP-ribose) (PAR) polymerase superfamily. ADP-ribosylation is initiated by PARPs, recognized by PAR binding proteins, and removed by PARG and other ADP-ribose hydrolases. These three groups of proteins work together to regulate the cellular and molecular response of PAR signaling, which is critical for a wide range of cellular and physiological functions.

• The KIPS Transactions:PartD
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• v.15D no.2
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• pp.257-262
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• 2008

This paper describes the implementations of the application service based on embedded Linux; Personal Audio Recorder (PAR) which uses WiBro network for data communications and CDMA network for voice communications. At PAR, when PAR client starts voice recording on a dual-mode terminal, the CDMA voice data of caller and callee is transmitted to storage server located in the Internet through WiBro network. Then, PAR server stores voice data on storage server according to the call number and call time. In case of shortage of storage space on terminal, PAR makes user to store voice data. And, PAR can search a catalog of stored data on server and play the specific content.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.15
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• pp.6429-6436
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• 2014

Poly-ADP-ribosylation (PAR) is a post-translational modification of mainly chromosomal proteins. It is known to be strongly involved in several molecular events, including nucleosome-remodelling and carcinogenesis. In this investigation, it was attempted to evaluate PAR level as a reliable biomarker for early detection of cancer in blood lymphocyte histones. PAR of isolated histone proteins was monitored in normal and dimethylnitrosamine (DMN)-exposed mice tissues using a novel ELISA-based immuno-probe assay developed in our laboratory. An inverse relationship was found between the level of PAR and period of DMN exposure in various histone proteins of blood lymphocytes and spleen cells. With the increase in the DMN exposure period, there was reduction in the PAR level of individual histones in both cases. It was also observed that the decrease in the level of PAR of histones resulted in progressive relaxation of genomic DNA, perhaps triggering activation of genes that are involved in initiation of transformation. The observed effect of carcinogen on the PAR of blood lymphocyte histones provided us with a handy tool for monitoring biochemical or physiological status of individuals exposed to carcinogens without obtaining biopsies of cancerous tissues, which involves several medical and ethical issues. Obtaining blood from any patient and separating blood lymphocytes are routine medical practices involving virtually no medical intervention, post-procedure medical care or trauma to a patient. Moreover, the immuno-probe assay is very simple, sensitive, reliable and cost-effective. Therefore, combined with the ease of preparation of blood lymphocytes and the simplicity of the technique, immuno-probe assay of PAR has the potential to be applied for mass screening of cancer. It appears to be a promising step in the ultimate goal of making cancer detection simple, sensitive and reliable in the near future.