• 한국정보통신학회논문지
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• 제15권1호
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• pp.99-106
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• 2011

유비쿼터스 컴퓨팅 기술과 헬스케어 기술이 접목되어 시간과 장소에 구애받지 않고, 지속적인 건강관리가 가능한 u-헬스케어 기술이 급부상하고 있으며, 한국의 최첨단 정보 환경을 기반으로 하여 향후 급증할 의료수요에 대처하기 위한 u-헬스케어 기반기술이 절실한 실정이다. 특히, u-헬스케어 분야에서 다루는 정보는 주로 건강이나 생명과 밀접한 관계가 있는 관련 정보로서 극히 개인적인 사항을 주로 포함한다. u-헬스케어 서비스가 보안 및 프라이버시 측면에서 많은 취약점과 위협이 존재한다는 점을 볼 때, 데이터 보호를 위한 기술적 대안이 기본적으로 요구된다. 이에 본 논문에서는 안전한 u-헬스케어 시스템을 위해 u-헬스케어 센서모듈을 설계 및 제작하고, USN의 안전성 및 데이터 보호를 위해 NLM-128 알고리즘을 TinyOS상에서 소프트웨어적으로 구현하여 USN 센서노드에 탑재하였다. 그리고 NLM-128 알고리즘에 고속 병렬형 PS-LFSR을 적용하여 암호화 시간을 단축 시켰다. u-헬스케어 응용을 위한 USN 보안센서노드는 환자의 몸에 부착되어 각종 생체 신호를 계측할 수 있으며, 계측된 생체신호들은 무선메쉬네트워크(Wireless Mesh Network)를 통해 통합서버로 전송되며, 그 결과는 실시간으로 모니터링이 가능하였다.

• Molecules and Cells
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• 제42권1호
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• pp.36-44
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• 2019

Alzheimer's disease (AD) is the most frequent age-related human neurological disorder. The characteristics of AD include senile plaques, neurofibrillary tangles, and loss of synapses and neurons in the brain. ${\beta}-Amyloid$ ($A{\beta}$) peptide is the predominant proteinaceous component of senile plaques. The amyloid hypothesis states that $A{\beta}$ initiates the cascade of events that result in AD. Amyloid precursor protein (APP) processing plays an important role in $A{\beta}$ production, which initiates synaptic and neuronal damage. ${\delta}-Catenin$ is known to be bound to presenilin-1 (PS-1), which is the main component of the ${\gamma}-secretase$ complex that regulates APP cleavage. Because PS-1 interacts with both APP and ${\delta}-catenin$, it is worth studying their interactive mechanism and/or effects on each other. Our immunoprecipitation data showed that there was no physical association between ${\delta}-catenin$ and APP. However, we observed that ${\delta}-catenin$ could reduce the binding between PS-1 and APP, thus decreasing the PS-1 mediated APP processing activity. Furthermore, ${\delta}-catenin$ reduced PS-1-mediated stabilization of APP. The results suggest that ${\delta}-catenin$ can influence the APP processing and its level by interacting with PS-1, which may eventually play a protective role in the degeneration of an Alzheimer's disease patient.

• 산업기술연구
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• 제24권B호
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• pp.47-57
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• 2004

This study is aiming to obtain the pabulum of architectural planning about out-patient clinic department in armed force hospital with search. The discussion was about characteristic problems and differentiated planning characteristics of common general hospital, So the conclusion of research is as follows. In army medical facilities, Because of architectural standard of out-patient clinic department about scale of facilities and characteristic in each examination-part is unprepared, it may have to be readied. Out-patient clinic department was become plan to scale about whole 7~8% in hospital to SB hospital in 95 but was planed about 5% of whole scale from PS hospital in 97. When plan hospital, increase of equipment and increase of module size about bed for the convenience of patient or employees are judged for cause in hospital since 97 years than previous hospital in 95.

• 산업융합연구
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• 제22권2호
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• pp.97-103
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• 2024

본 연구의 목적은 비만 뇌졸중 환자의 균형 훈련이 체성분과 균형 능력 회복에 미치는 영향을 살펴보는 것이었다. 운동 프로그램은 비만군과 정상 체중 군을 동일하게 실험군(obesity)과 대조군(정상체중)으로 나누어 하루 30분, 일주일에 5일 동안 균형 훈련을 실시했다. 실험군과 대조군 모두 사전, 사후 체성분과 BSS(Biodex Medical Systems)를 8주간 수집하였다. 그 결과 그룹 내 체성분 자료를 비교해 보면 비만군은 모든 매개변수에서 유의한 차이를 보였다(p<.05). 또한 그룹 간 모든 매개변수 간에도 통계적인 차이를 보였다(p<.05). LOS(Limits Of Stability)의 그룹 내 자료를 비교해 보면, 비만군은 '후면'과 '좌측'을 제외한 모든 매개변수에서 유의한 차이를 보였다(p<.05). 그룹 간 자료에서 '전방' 매개변수는 유의한 차이를 보였다. PS(Posture Stability)의 그룹 내 자료를 비교해 보면, 비만군은 모든 매개변수에서 유의한 차이를 보였고(p<.05), 그룹 간 PS(Posture Stability) 결과는 'Med/lat'(p=.000)만으로 유의한 차이를 보였다. 이상의 결과를 종합해 보면, 균형 훈련이 비만이 있는 뇌졸중 환자의 균형 능력 및 체성분에 영향을 미치는 것으로 나타났다.

• Journal of Chest Surgery
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• 제49권2호
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• pp.112-114
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• 2016

The half-turned truncal switch (HTTS) operation has been reported as an alternative to the Rastelli or $r{\acute{e}}paration$ $\grave{a}$ $l^{\prime}{\acute{e}}tage$ ventriculaire procedures. HTTS prevents left ventricular outflow tract (LVOT) obstruction in patients with complete transposition of the great arteries (TGA) with a ventricular septal defect (VSD) and pulmonary stenosis (PS), or in those with a Taussig-Bing anomaly with PS. The advantages of the HTTS procedure are avoidance of late LVOT or right ventricular outflow tract (RVOT) obstruction, and of overstretching of the pulmonary artery. We report the case of a patient who underwent HTTS for TGA with VSD and PS, in whom there was no LVOT obstruction and only mild aortic regurgitation and mild RVOT obstruction, including observations at 12-year follow-up. Our experience with long-term follow-up of HTTS supports a solution for late complications after the Rastelli procedure.

• Journal of Chest Surgery
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• 제15권3호
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• pp.331-337
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• 1982

Complete TGA is a common congenital cardiovacular anomaly, and without palliative or corrective surgery, the infant born with TGA rarely survives the first year of life. Hemodynamically, recirculated blood flow in the systemic and pulmonary circuit has a key role in systemic arterial oxygen saturation and the status of the pulmonary vascular bed. Recently a d-TGA with VSD and PS, in a 12 year old male patient had been tried for inversion of the ventricular flow with Rastelli operation. An intracardiac tunnel was constructed between the VSD and the aortic orifice to connect the ventricle to the aorta. The right ventricle was connected with the pulmonary circulation by anastomosis of an valved conduit between the right ventricle and the distal end of the pulmonary artery. During the postop, period, the irreversible renal failure, accompanied by metabolic acidosis and pulmonary edema, occured under relative stabilized cardiac performance state. The autopsy was done, which revealed diffuse infarcted area in both kidney and preserved intra & extracardiac graft constructed.

• The Journal of Advanced Prosthodontics
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• 제15권4호
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• pp.179-188
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• 2023

PURPOSE. This in vitro study aimed to evaluate the performance of digital intraoral scanners in a completely edentulous patient with angled and parallel implants. MATERIALS AND METHODS. A total of 6 implants were placed at angulations of 0°, 5°, 0°, 0°, 15°, and 0° in regions #36, #34, #32, #42, #44, and #46, respectively, in a completely edentulous mandibular polyurethane model. Then, the study model created by connecting a scan body on the implants was scanned using a model scanner, and a 3D reference model was obtained. Three different intraoral scanners were used for digital impressions (PS group, TR group, and CS group, n = 10 in each group). The distances and angles between the scan bodies in these measurement groups were measured. RESULTS. While the Primescan (PS) impression group had the highest accuracy with 38 ㎛, the values of 104 ㎛ and 171 ㎛ were obtained with Trios 4 IOSs (TR) and Carestream 3600 (CS), respectively (P = .001). The CS scanner constituted the impression group with the highest deviation in terms of accuracy. In terms of dimensional differences in the angle parameter, a statistically significant difference was revealed among the mean deviation angle values according to the scanners (P < .001). While the lowest angular deviation was obtained with the PS impression group with 0.185°, the values of 0.499° and 1.250° were obtained with TR and CS, respectively. No statistically significant difference was detected among the impression groups in terms of precision values (P > .05). CONCLUSION. A statistically significant difference was found among the three digital impression groups upon comparing the impression accuracy. Implant angulation affected the impression accuracy of the digital impression groups. The most accurate impressions in terms of both distance and angle deviation were obtained with the PS impression group.

• 한국의학물리학회지:의학물리
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• 제21권4호
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• pp.340-347
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• 2010

단층치료기(TomoTherapy$^{(R)}$)를 이용한 방사선 치료에서 환자별 정도관리인 DQA (delivery quality assurance)는 보통 이온 전리함과 필름을 이용한다. DQA의 결과는 치료계획장비인 TomoPS (Tomo Planning Station)를 이용하여 분석하게 되는데 필름을 이용한 2차원 선량분포의 비교는 감마인덱스 분석을 사용한다. 감마인덱스를 이용한 비교는 3%/3 mm와 같은 기준을 사용하여 이 기준을 통과한 비율(pass rate)이 허용 값보다 크게 되는지 확인한다. TomoPS는 pass rate 값을 정량적으로 계산해주는 기능이 없다. 본 논문에서는 TomoPS 감마인덱스 분석의 pass rate를 정량적으로 계산하는 방법을 제시하고 이를 계산해주는 프로그램인 PassRT를 개발하였다. PassRT의 검증을 위해 I'mRT MatriXX (IBA Dosimetry, Germany)를 사용하여 측정한 세기조절방사선 치료를 받은 환자의 환자별 정도관리 자료와 필름을 사용한 DQA 자료를 사용하였다. 두 가지 종류의 자료에 대해 PassRT로 계산한 pass rate를 OmniPro I'mRT (IBA Dosimetry, Germany)프로그램으로 계산한 pass rate와 비교하였다. MatriXX를 이용하여 측정한 자료의 비교결과 평균오차 0.00%, 표준편차 0.01%, 최대오차 0.04%였고, 필름의 결과는 평균오차 0.00%, 표준편차 0.02%, 최대오차 0.02%였다. 관심영역이 $24.3{\times}16.6cm^2$ 보다 작은 경우 본 논문에서 제시한 방법으로 감마인덱스 분석의 pass rate를 소수점 첫째자리 까지 정확하게 계산할 수 있어서 보다 정확한 단층치료기의 DQA에 도움이 될 것으로 생각된다.

• 사상체질의학회지
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• 제35권1호
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• pp.46-55
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• 2023

Objectives The purpose of this case study was to report a case of anorexia and fatigue after getting vaccinated COVID-19 treated based on Sasang Constitutional Medicine. Methods The patient was hospitalized for 4 days and treated with herbal medicine and moxibustion. The patient was asked to score for daily energy level out of 100 on his own and we used Karnofsky Performance Score(Karnofsky PS) on daily health status to evaluate the clinical effects. We also checked daily amount of meal and evaluated original symptoms such as insomnia, gastric discomfort, bowel movement and dysuria in four stages. Results At initial, the patient could only eat one spoon of a meal and was unable to carry on herself without any assistance, so she used a wheelchair on the day of admission. When discharged, the patient can eat half of a meal at each mealtime and perform normal activities by herself. Discussion This case demonstrates that Sasang constitutional approach to anorexia and fatigue caused by COVID-19 vaccination can be an useful treatment.

• The Korean Journal of Pain
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• 제22권3호
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• pp.216-223
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• 2009

Background: There have been limited reports on the effectiveness of 5% lidocaine patches (L5Ps) for treating a few types of chronic pain. We utilized L5Ps for chronic pain patients with various diagnoses and who had incompletely responded to their current treatment regimen. This study aimed at describing the results of a retrospective review of an open-label L5P trial to assess L5Ps' effectiveness and safety for treating various chronic pain patients. Methods: The chronic pain patients with pain lasting longer than 6-month duration were offered a 2-week L5P treatment trial. The patients were maintained on their other analgesic regimens. The treatment effect was measured according to the change from the baseline visual analog scale (VAS) to the week 2 VAS. After a 2-week trial, the patients were asked if they perceived pain improvement with L5Ps by using a four-item Pain Relief Scale (1 = a lot of relief, 2 = slight relief, 3 = no change, 4 = worse pain). Results: In the combined patient population (n = 177), 2-week treatment with the L5Ps significantly improved the week 2 VAS (P = 0.000). Significant improvement in the VAS was reported by the chronic pain patients with postherpetic neuralgia, intercostal neuralgia, degenerative osteoarthritis at knee joint, and other maladies. A higher proportion of the chronic pain patients reported improving their pain by the L5Ps. Seven patients experienced mild or moderate patch-related adverse events. Conclusions: The L5P provided clinically meaningful pain relief in some refractory chronic pain patients without any severe adverse events.