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Effects of shirodhara in generalized anxiety disorder

  • Rastogi, Sanjeev;Baiswar, Antriksha;Nischal, Anil;Srivastava, Prem Swarup;Nischal, Anuradha
    • CELLMED
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    • v.6 no.4
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    • pp.27.1-27.4
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    • 2016
  • Anxiety is a common clinical presentation. Primary anxiety poses a significant problem in its management. Many among the current treatment options of anxiety are habit forming causing significant withdrawal symptoms. There are dose dependent responses often associated with drug adversities. Day time sedation is an undesired effect of many drugs used for anxiety management limiting its usage. Ayurveda recommends a bio- physical procedure to manage anxiety. Shirodhara, a dripping procedure is utilized as a front line therapy for anxiety in Ayurveda. Seeing the limitations of conventional biomedical management of anxiety requiring an improvement upon the existing protocols of managements, and also seeing the use of shirodhara for anxiety management in ayurvedic clinics, a pragmatic study to evaluate the effect of shirodhara in generalized anxiety disorder was done. This was a pragmatic study consisting of shirodhara with ksheer bala oil as an intervention upon generalized anxiety disorder patients. The study was conducted upon 13 patients and observations were done for six weeks. The responses observed through the changes in Hamilton Anxiety Scale were evaluated using paired t test to observe the pre-post significance.

BLUE-Based Channel Estimation Technique for Amplify and Forward Wireless Relay Networks

  • PremKumar, M.;SenthilKumaran, V.N.;Thiruvengadam, S.J.
    • ETRI Journal
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    • v.34 no.4
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    • pp.511-517
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    • 2012
  • The best linear unbiased estimator (BLUE) is most suitable for practical application and can be determined with knowledge of only the first and second moments of the probability density function. Although the BLUE is an existing algorithm, it is still largely unexplored and has not yet been applied to channel estimation in amplify and forward (AF)-based wireless relay networks (WRNs). In this paper, a BLUE-based algorithm is proposed to estimate the overall channel impulse response between the source and destination of AF strategy-based WRNs. Theoretical mean square error (MSE) performance for the BLUE is derived to show the accuracy of the proposed channel estimation algorithm. In addition, the Cram$\acute{e}$r-Rao lower bound (CRLB) is derived to validate the MSE performance. The proposed BLUE channel estimation algorithm approaches the CRLB as the length of the training sequence and number of relays increases. Further, the BLUE performs better than the linear minimum MSE estimator due to the minimum variance characteristic exhibited by the BLUE, which happens to be a function of signal-to-noise ratio.

Improvement of Metallic Micro-Structure Precision Employing Two-photon Induced Photoreduction Process (이광자 흡수 광환원 공정을 이용한 마이크로 금속형상 제작의 정밀화에 관한 연구)

  • Son, Yong;Lim, Tae-Woo;Yang, Dong-Yol;Prem, Prabhakaran;Lee, Kwang-Sup
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.32 no.9
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    • pp.754-760
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    • 2008
  • A two-photon induced photoreduction process suggests a possibility for fabricating complicated metallic microstructures which can be applied to 3-D micro-circuits and optical devices, etc. The process employs the photoreduction of silver ions in a metallic solution which is composed of metallic salt ($AgNO_3$) and watersoluble polymer ((poly(4-styrenesulfonique acid) 18wt. % in $H_2O$, $(C_8H_8O_3S)_n$)). In this process, the improvement of the resolution and the uniformity of fabricated metallic structures are important issues. To address these problems, continuous forming window (CFW) is obtained from a parametric study on the conditions of laser power and scanning velocity and the direct seed generation (DSG) method is proposed. Silver nano particles are uniformly generated in a metallic solution through the DSG method, which enables the decrease of a laser power to trigger the photoreduction of silver ions as well as the increase of metal contents in a metallic solution. So the two-photon induced photoreduction property of a metallic solution is improved. Through this work, precise silver patterns are fabricated with a minimum line width of 400 nm.

Reliability based partial safety factor of concrete containing nano silica and silica fume

  • Nanda, Anil Kumar;Bansal, Prem Pal;Kumar, Maneek
    • Computers and Concrete
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    • v.26 no.5
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    • pp.385-395
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    • 2020
  • The influence of combination of nano silica and silica fume, as partial cement replacement materials, on the properties of concrete has been studied through the measurement of compressive strength. The compressive strength of concrete in terms of mean, standard deviation and with-in-test coefficient of variation related to the variation in the nominated parameters have also been developed. The compressive strength data developed experimentally has been analyzed using normal-probability distribution and partial safety factors of composite concretes have been evaluated by using first order second moment approach with Hasofer Lind's method. The use of Nano silica and silica fume in concrete decreases the partial safety factor of concrete i.e., increase the reliability of concrete. The experimental results show that the properties of concrete having nano silica and silica fume in combination were better than that of a plain concrete. The SEM test results showing the level of Ca(OH)2 in plain concrete and consumption level Ca(OH)2 of concrete containing nano silica & silica fume have also been presented.

Pelvic Hydatidosis Mimicking a Malignant Multicystic Ovarian Tumor

  • Singh, Prem;Mushtaq, Deeba;Verma, Neetu;Mahajan, N.C.
    • Parasites, Hosts and Diseases
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    • v.48 no.3
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    • pp.263-265
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    • 2010
  • Echinococcosis is a multisystem disease and has propensity to involve any organ, an unusual anatomical site, and can mimic any disease process. Primary peritoneal echinococcosis is known to occur secondary to hepatic involvement but occasional cases of primary peritoneal hydatid disease including pelvic involvement have also been reported. We report here 1 such case of primary pelvic hydatidosis mimicking a malignant multicystic ovarian tumor where there was no evidence of involvement of the liver or spleen. Our patient, a 27-year-old female, was detected to have a large right cystic adnexal mass on per vaginal examination which was confirmed by ultrasonography. Her biochemical parameters were normal and CA-125 levels, though mildly raised, were below the cut off point. She underwent surgery and on exploratory laparotomy, another cystic mass was found attached to the mesentery of the small gut. The resected cysts were processed histopathologically. On cut sections both large cysts revealed numerous daughter cysts. Microscopic examination of fluid from the cysts revealed free scolices with hooklets and the cyst wall had a typical laminated membrane with inner germinal layer containing degenerated protoplasmic mass. The diagnosis of pelvic hydatid disease was confirmed and patient was managed accordingly. Hydatid disease must be considered while making the differential diagnosis of pelvic cystic masses, especially in endemic areas.

Assessing Bank Competition in Nepal Using Panzar-Rosse Model

  • BUDHATHOKI, Prem Bahadur;RAI, Chandra Kumar;RAI, Arjun
    • The Journal of Asian Finance, Economics and Business
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    • v.7 no.11
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    • pp.759-768
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    • 2020
  • The purpose of this study is to assess the state of competition in Nepalese banking over the period from 2010 to 2019. This study employs panel data and a non-structural Panzar-Rosse model to measure the degree of competition in the Nepalese banking industry. The first reduced-form equation is applied to gauge competition, and the second model is used to test the long-run equilibrium in the banking market. The finding reveals that the Nepalese banking market is equilibrium in the long-run. It implies that the factor prices do not affect ROA in the long-run. The result of the H-statistic shows that the Nepalese banking system is operating under the state of perfect competition and is shifted from monopolistic competition to perfect competition. The reduced-form model reveals that the interest income is positive and significantly affected by factor prices. Similarly, the macroeconomic variable GDP growth is positively related to interest income. On the contrary, the bank's specific factors risk and the number of bank branches are inversely associated with the regressand. The outcomes of the study may be advantageous to the policymakers, especially to Nepal Rastra Bank to implement monetary policy and M&A policy for the stability and growth of the financial system of Nepal.

Synthesis and Catalytic Applications of Ruthenium(0) Nanoparticles in Click Chemistry

  • Kumar, Avvaru Praveen;Baek, Min-Wook;Sridhar, Chirumarry;Kumar, Begari Prem;Lee, Yong-Ill
    • Bulletin of the Korean Chemical Society
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    • v.35 no.4
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    • pp.1144-1148
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    • 2014
  • Here we report a facile synthesis of ruthenium (Ru) Nanoparticles (NPs) by chemical co-precipitation method. The calcination of ruthenium hydroxide samples at $500^{\circ}C$ under hydrogen atmosphere lead to the formation of $Ru^0$ NPs. The size and aggregation of Ru NPs depends on the pH of the medium, and type of surfactant and its concentration. The X-ray diffraction (XRD), scanning electron microscope (SEM) and transmission electron microscope image (TEM) analyses of particles indicated the formation of $Ru^0$ NPs, and have 10 to 20 nm sizes. As-synthesized $Ru^0$ NPs are characterized and investigated their catalytic ability in click chemistry (azidealkyne cycloaddition reactions), showing good results in terms of reactivity. Interestingly, small structural differences in triazines influence the catalytic activity of $Ru^0$ nanocatalysts. Click chemistry has recently emerged to become one of the most powerful tools in drug discovery, chemical biology, proteomics, medical sciences and nanotechnology/nanomedicine. In addition, preliminary tests of recycling showed good results with neither loss of activity or significant precipitation.

Comparison of Gene Coding Clones Content in In vivo and In vitro Methyl-Filtration Libraries of Maize(Zea may)

  • Lee, Myung-Chul;Wing, Rod A;Suh, Seok-Cheol;Eun, Moo-Young
    • Korean Journal of Plant Resources
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    • v.20 no.6
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    • pp.491-498
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    • 2007
  • It has been hypothesized that efficient exclusion of methylated retrotransposons and repeated DNA region is one of the rapid and cost-effective approaches for comprehensive gene discovery in large genome size of maize. Three kinds of methylation-sensitive restriction enzymes, HapII, MspI and McrBC, were used to identify the restriction frequency of cytosine methylation sites in maize genome. Roughly 60% of total maize genomic DNA was restricted less than 500bp by McrBC, and the most of restricted small size fraction was composed retrotransposon. In order to validate the efficient construction of gene-rich shotgun library, we compare two gene-rich methyl-filtration shotgun libraries using in vivo and in vitro methyl-filtration system. The size selected DNA fraction by Sau3A-McrBC enzyme treated was very stable and has not appeared modification in E. coli, but most insert DNA size of partially digested with Sau3A were decrease less than 500bp by bacterial methylation-modification system. In compare of retroelements portion, A 44.6% of the sequences were retroelement in unmethyl-filtered library, and the most of them was Copia type, such as Prem, Opie and Ji. The portion of retroelement was drastically decreased to 25% and 20% by in vivo and in vitro filtration system, respectively.

Photocatalytic degradation and antibacterial investigation of nano synthesized Ag3VO4 particles @PAN nanofibers

  • Saud, Prem Singh;Ghouri, Zafar Khan;Pant, Bishweshwar;An, Taehee;Lee, Joong Hee;Park, Mira;Kim, Hak-Yong
    • Carbon letters
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    • v.18
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    • pp.30-36
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    • 2016
  • Well-dispersed Ag3VO4 nanoparticles @polyacrylonitrile (PAN) nanofibers were synthesized by an easily controlled, template-free method as a photo-catalyst for the degradation of methylene blue. Their structural, optical, and photocatalytic properties have been studied by X-ray diffraction, transmission electron microscopy, field-emission scanning electron microscopy equipped with rapid energy dispersive analysis of X-ray, photoluminescence, and ultraviolet-visible spectroscopy. The characterization procedures revealed that the obtained material is PAN nanofibers decorated by Ag3VO4 nanoparticles. Photocatalytic degradation of methylene blue investigated in an aqueous solution under irradiation showed 99% degradation of the dye within 75 min. Finally, the antibacterial performance of Ag3VO4 nanoparticles @PAN composite nanofibers was experimentally verified by the destruction of Escherichia coli. These results suggest that the developed inexpensive and functional nanomaterials can serve as a non-precious catalyst for environmental applications.

Development of high performance hybrid fiber reinforced concrete using different fine aggregates

  • Gupta, Hitesh;Bansal, Prem Pal;Sharma, Raju
    • Advances in concrete construction
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    • v.11 no.1
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    • pp.19-32
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    • 2021
  • In the present experimental study, the high performance hybrid fiber reinforced concrete (HPHFRC) is prepared using the Modified Andreasen and Andersen (A&A) particle packing model. Total of 16 trial mixes of HPHFRC with Indian standard sand (SS) and natural river sand (NS) are prepared to achieve the selection criteria (flow percent>150 and compressive strength>80 MPa). Based on the flow percent and compressive strength criteria, the selected mixes evaluated to study the effect of usage of natural river sand (NS) and the expensive Indian standard sand (SS) on the mechanical, durability, and microstructure property of designed HPHFRC. It has been found that the Modified A&A model is reliable to design the mix for HPHFRC with excellent mechanical, durability, and microstructure properties. In addition to that, a moderate difference in the mechanical and durability properties of NS contained HPHFRC and SS contained HPHFRC is found. Based on the obtained results of NS contained HPHFRC, it can be concluded that the use of natural river sand (NS) can be successfully adopted for the production of HPHFRC, resulted in a reduction of the production cost without compromising the excellent performance of HPHFRC.