• Journal of Plant Biotechnology
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• 제38권1호
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• pp.62-68
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• 2011

원예작물의 생육을 저하시키는 각종 병충해로 인한 과도한 농약과 화학비료의 사용은 환경오염뿐만 아니라 작물의 생산량에도 큰 영향을 미치고 있다. 식물생명공학기술을 이용하여 농약이나 화학비료 사용량을 획기적으로 줄일 수 있는 식물체의 개발, 즉 형질전환을 이용한 분자 육종기술은 병충해 내성 농작물을 개발하여 과도한 화학비료의 사용에 따르는 여러가지 문제점들을 극복할 수 있는 대안으로 대두되고 있다. 본 연구에서는 모델식물인 애기장대에서 분리한 식물생체방어 신호전달에 관련된 AtCBP63 유전자를 감자에 과발현시켰고, 이러한 형질 전환 감자에서 병저항성에 관여하는 유전자인 PR-2, PR-3, PR-5 유전자들의 발현이 증가되어 지속적으로 식물 방어 기작이 활성화되어 있음을 확인하였다. 또한, 감자에서 무름병 (soft rot disease)을 일으켜 막대한 피해를 유발하는 병원성 세균인 Erwinia carotovora subsp. Carotovora (Ecc)를 이용하여 AtCBP63 유전자를 과발현한 감자에 감염시켰을 때, 병 저항성이 증가한다는 사실을 검증하였다. 앞으로, 다양한 곰팡이 균에 대응하여 AtCBP63 유전자를 과발현한 감자에 저항성을 검증하고자 한다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권9호
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• pp.3913-3916
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• 2015

Objective: To evaluate the efficacy of mannatide combined with sodium cantharidate vitamin B6 in the treatment of malignant pleural effusions. Materials and Methods: Data for 69 patients with malignant pleural effusions who did not receive systemic chemotherapy were collected. Injection into the thorax using mannatide combined with sodium cantharidate vitamin B6 was performed for 37 patients in the experimental group and mannatide combined with cisplatin for 32 patients in the control group. Objective responses, KPS (Karnofsky Scoring) and incidences of side effects between the two groups were compared. Results: 13 patients reached CR (complete response) and 11 PR (partial response) in the experimental group, while 12 patients reached CR and 9 PR in the control group, the difference in overall objective responses between the two groups not being significant (66.7% vs 63.6%, p=0.806). However, improvement of KPS in the experimental group wasgreater than in the control group; total side-effect incidences during the period of treatment were 22.2% (8/36) and 54.5% (18/33), respectively (p=0.006). Conclusions: Regimen of mannatide combined with sodium cantharidate vitamin B6 had better improvement in quality-of-life and symptom relief, with a lower side-effect incidence in treatment of malignant pleural effusions.

• 전력전자학회논문지
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• 제22권5호
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• pp.440-448
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• 2017

This paper proposes a controller design of a distributed source inverter in stand-alone mode or grid-connected mode to compensate the current or voltage harmonics caused by local nonlinear load. The PR-based multi loop controller has been used to improve the dynamic performance of the system and to compensate the output voltage or grid current harmonics. The multi-loop controller consists of an outer current controller and an inner voltage controller for the output voltage control in stand-alone mode. In grid-connected mode, an outer current controller is added to the output voltage controller for the grid current control. The design performance of each controller is described through the Root locus and Bode plot of the transfer functions. The validity of the proposed control algorithm and design parameters has been verified through the PSiM simulation and experimental results.

• Journal of Power Electronics
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• 제19권5호
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• pp.1087-1098
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• 2019

In this paper, a detuning factor (DeFac) method is proposed to design the key parameters for optimizing the transfer power and efficiency of an Inductively Coupled Power Transfer (ICPT) system with primary-secondary side compensation. Depending on the robustness of the system, the DeFac method can guarantee the stability of the transfer power and efficiency of an ICPT system within a certain range of resistive-capacitive or resistive-inductive loads. A MATLAB-Simulink model of a ICPT system was built to assess the system's main evaluation criteria, namely its maximum power ratio (PR) and efficiency, in terms of different approaches. In addition, a magnetic field simulation model was built using Ansoft to specify the leakage flux and current density. Simulation results show that both the maximum PR and efficiency of the ICPT system can reach almost 70% despite the severe detuning imposed by the DeFac method. The system also exhibited low levels of leakage flux and a high current density. Experimental results confirmed the validity and feasibility of an ICPT system using DeFac-designed parameters.

• Asian Pacific Journal of Cancer Prevention
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• 제14권6호
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• pp.3937-3940
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• 2013

Objective: To explore the expression and significance of estrogen receptor (ER), progestrone receptor (PR), vascular endothelial growth factor (VEGF), CA15-3, CA125 and carcinoma embryonic antigen (CEA) expression in judging the prognosis of breast cancer. Materials and Methods: Sixty-five patients with breast cancer undergoing operations in the general surgery department were considered as the observation group, and 50 healthy outpatients of our hospital as the control group. Cubital venous blood was drawn in the morning from fasting patients in the two groups and chemiluminescence immunoassays were used to detect the levels of CA15-3, CA125 and CEA in serum. The follow-up duration was from 4 months to 2 years, and change in levels of the indicators was detected by dynamically drawing blood. After surgery, cancer tissue samples of patients in observation group remained on file (the non-recurrent patients were biopsied). Immunohistochemistry was applied to determine the expression of ER, PR and VEGF in tissue. Results: The effective rate of 12 patients with negative ER and PR expression was 33.3% in the observation group, being associated with prognosis to varying extents. Serum CA15-3, CA125 and CEA in the observation group were all significantly higher than in control group (p<0.01). With increase in pathological staging, levels of serum CA15-3, CA125 and CEA gradually increased (p<0.01). Levels in patients with lymph node metastasis were markedly higher than in those without (p<0.01). In addition, values with distal lymph node metastasis were notably higher than with adjacent lymph node metastasis (p<0.01). The postoperative follow-up results revealed that positive VEGF and levels of serum VEGF, CA15-3, CA125 and CEA in recurrence group were obviously higher than in non-recurrence group (p<0.01). Conclusions: Joint detection of ER and PR expression as well as levels of serum VEGF, CA15-3, CA125 and CEA is meaningful and can guide the diagnosis and treatment for breast cancer.

• 한국도로학회논문집
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• 제16권2호
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• pp.43-52
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• 2014

PURPOSES : To solve problems in current compaction control DCPT(Dynamic Cone Penetrometer Test), highly correlated with various testing methods, simple, and economic is being applied. However, it、s hard to utilize DCPT results due to the few numerical analyses for DCPT have been performed and the lack of data accumulation. Therefore, this study tried to verify the validation of numerical modeling for DCPT by comparing and analyzing the results of numerical analyses with field tests. METHODS: The ground elastic modulus and PR(Penetration Rate) value were estimated by using PFC(Particle Flow Code) 3D program based on the discrete element method. Those values were compared and analyzed with the result of field tests. Also, back analysis was conducted to describe ground elastic modulus of field tests. RESULTS : Relative errors of PR value between the numerical analyses and field tests were calculated to be comparatively low. Also, the relationship between elastic modulus and PR value turned out to be similar. CONCLUSIONS : Numerical modeling of DCPT is considered to be suitable for describing field tests by carrying out numerical analysis using PFC 3D program.

• Mycobiology
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• 제32권1호
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• pp.47-53
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• 2004

Pseudomonas fluorescens 1-94 induced systemic resistance in chickpea against Fusarium wilt of chickpea caused by Fusarium oxysporum f. sp. ciceri by the synthesis and accumulation of phenolic compounds, phenylalanine ammonia lyase(PAL) and pathogenesis related(PR) proteins(chitinase, $\beta$-1,3-glucanase and peroxidase). Time-course accumulation of these enzymes in chickpea plants inoculated with P. fluorescens was significantly(LSD, P=0.05) higher than control. Maximum activities of PR-proteins were recorded at 3 days after inoculation in all induced plants; thereafter, the activity decreased progressively. Five PR peroxidases detected in induced chickpea plants. Molecular mass of these purified peroxidases was 20, 29, 43, 66 and 97 kDa. Purified peroxidases showed antifungal activity against plant pathogenic fungi.

• 전기학회논문지
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• 제64권7호
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• pp.1012-1018
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• 2015

The studies on the operating performance analysis or design about the fixed tilt angle flat-plate photovoltaic (PV) system are still lively going off. However the operating property analysis about the arch type PV system which means PV array were designed as round type is dissatisfied. In this paper, we theoretically established the factors which are cause of the deterioration in performance of arch type PV system. In addition, we use the Solar Pro simulation tools to design both flat-plate type and arch type 30kW PV systems. The simulations about arch type PV system applied two ways such as central inverter and string inverter were conducted. The performance ratio (PR) of the PV system with flat-plate type shows the highest value 74[%] when the tilt angle is 30°. In case of arch type, when applying central inverter method, PR value shows approximately 73[%] and no more difference with arch type of the PV array. This value shows 1[%] decrease compare with the flat-plate type. However when applying string inverter methods, the average PR value shows 80 % and 6% improved than the central inverter method.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2014년도 제46회 동계 정기학술대회 초록집
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• pp.366.1-366.1
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• 2014

The rare-earth oxides M2O3 (M=La, Pr, Gd) are good insulators due to their large band gap (3.9eV for Pr2O3, 5.6eV for Gd2O3), they have high dielectric constants (Gd2O3 K=16, La2O3 K=27, Pr2O3 K=26-30) and, compared to ZrO2 and HfO2, they have higher thermodynamic stability on silicon making them very attractive materials for high-K dielectric applications. Another attractive feature of some rare-earth oxides is their relatively close lattice match to that of silicon, offering the possibility of epitaxial growth and eliminating problems related to grain boundaries in polycrystalline films. Metal-organic chemical vapor deposition (MOCVD) has been preferred to PVD methods because of the possibility of large area deposition, good composition control and excellent conformal step coverage. Herein we report on the synthesis of rare-earth oxide complexes with designed alkoxide and aminoalkoxide ligand. These novel complexes have been characterized by means of FT-IR, elemental analysis, and thermogravimetric analysis (TGA).

• Journal of Power Electronics
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• 제13권3호
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• pp.469-478
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• 2013

This paper proposes a novel scheme for the current controller for the grid-side converter (GSC) of permanent-magnet synchronous generator (PMSG) wind turbines to eliminate the high-order harmonics in the grid currents under grid voltage disturbances. The voltage unbalance and harmonics in three-phase systems cause grid current distortions. In order to mitigate the input current distortions, multi-loop current controllers are applied, where the positive-sequence component is regulated by proportional-integral (PI) controllers, and the negative-sequence and high-order harmonic components are regulated by proportional-resonance (PR) controllers. For extracting the positive/negative-sequence and harmonic components of the grid voltages and currents without a phase delay or magnitude reduction, composite observers are applied, which give faster and more precise estimation results. In addition, an active damping method using PR controllers to damp the grid current component of the resonant frequency is employed to improve the operating stability of VSCs with inductor-capacitor-inductor (LCL) filters. The validity of the proposed method is verified by simulation and experimental results.