• Title/Summary/Keyword: PR(1 2 2 1)

Search Result 1,271, Processing Time 0.028 seconds

Hyperfractionated Radiotherapy and Concurrent Chemotherapy for Stage III Unresectable Non Small Cell Lung Cancer : Preliminary Report for Response and Toxicity (절제 불가능한 제 3기 비소세포성 페암의 다분할 방사선 치료와 MVP 복합 항암요법의 동시 치료에 대한 예비적 결과)

  • Choi, Eun-Kyung;Kim, Jong-Hoon;Chang, Hye-Sook;Kim, Sang-We;Suh, Cheol-Won;Lee, Kyoo-Hyung;Lee, Jung, Shin;Kim, Sang-Hee;Ko, Youn-Suk;Kim, Woo-Sung;Kim, Dong-Soon;Kim, Won-Dong;Song, Koun-Sik
    • Radiation Oncology Journal
    • /
    • v.13 no.2
    • /
    • pp.157-162
    • /
    • 1995
  • Lung cancer study group at Asan Medical Center has conducted the second prospective study to determine the efficacy and feasibility of MVP chemotherapy with concurrent hyperfractionated radiotherapy for Patients with stage III unresectable non-small cell lung cancer(NSCLC). All eligible Patients with stage III unresectable NSCLC were treated with hyperfractionated radiotherapy(120 cGy/fx BID. 6480 cGy/54fx) and concurrent 2 cycles of MVP(Mitomycin C $6mg/m^2,$ d2 & d29.Vinblastine $6mg/m^2,$ d2 & d29, Cisplatin $60mg/m^2,$ dl & d28) chemotherapy. Between Aug. 1993 and Nov. 1994, 62 patients entered this study; $6(10\%)$ had advanced stage IIIa and $56(90\%)$ had IIIb disease including 11 with pleural effusion and 10 with supraclavicular metastases. Among 62 patients, $48(77\%)$ completed planned therapy. Fourteen patients refused further treatment during chemoradiotherapy. Of 46 patients evaluable for response, $34(74\%)$ showed major response including $10(22\%)$ with complete and $24(52\%)$ with partial responses. Of 48 patients evaluable for toxicity, $13(27\%)$ showed grade IV hematologic toxicity but treatment delay did not exceed 5 days Two patients died of sepsis during chemoradiotherapy. Severe weight loss(more than $10\%)$ occurred in 9 patients$(19\%)$ during treatment. Nine patients$(19\%)$ developed radiation pneumonitis Six of these patients had grade 1 (mild) Pneumonitis with radiographic changes within the treatment fields Three other patients had grade 11 Pneumonitis, but none of these patients had continuous symptoms after steroid treatment. Concurrent chemoradiotherapy for patients with advanced NSCLC was well tolerated with acceptable toxicity and achieved higher response rates than the first study, but rather low compliance $rate(77\%)$ in this study is worrisome. We need to improve nutritional support during treatment and to use G-CSF to improve leukopenia and if necessary. supportive care will be given as in patients, Longer follow-up and larger sample size is needed to observe survival advantage.

  • PDF

Effects of Full Body Massage on Labor Pain and Delivery Stress Reaction for Primipara during Labor (분만 중 전신마사지가 초산부의 분만진통과 분만스트레스 반응에 미치는 효과)

  • Lee, Kun-Ja;Chang, Chun-Ja;Jo, Hyun-Sook
    • Women's Health Nursing
    • /
    • v.9 no.3
    • /
    • pp.224-234
    • /
    • 2003
  • Purpose: This study was to test the effects of a full body massage on labor pain and delivery stress reaction for primipara during labor. Method: This study employed a quasi- experimental method(nonequivalent control group, pre-post test design). The subjects of this study were 57 primipara hospitalized at the U OB & GYN hospital in Inchon from November 1. 2001 to July 31, 2002. 28 women were assigned to the experimental group and 29 to the control group. The experimental group was given 20 minutes full body massage for each of three delivery phases. The control group was given conventional delivery care. The levels of labor pain were measured by the Visual Analogue Scale and the expression scores of the labor pain and the levels of delivery stress reaction were measured by pulse rate, respiration rate, and blood pressure, and State-Anxiety Scale. Data were analyzed using the repeated measures analysis of covariance(ANCOVA), t-test, $X^2$- test, simple ANCOVA with SPSS program. Result: There was no interaction effect between time and group(F=.370, p=.693), but significant time effects were found for subjective labor pain(F=3.840, p=.028). There was no interaction effect between time and group(F=.112, p=.894), but significant group effects were found for objective labor pain(F=12.299, p=.001). There was no interaction effect between time and group for PR(F=.172, p=.843), RR(F=.626, p=.539), SBP(F=.089, p=.915), DBP(F=.748, p=.479), but significant group effects were found for SBP(F=7.547, p=.008). The level of status anxiety of the experimental group was significantly lower than the control group(F=11.787, p=.001). Conclusion: This study showed that the full body massage has partially positive effect on labor pain and delivery stress reaction. Therefore this study suggested that the full body massage might be used clinically to help primipara during labor.

  • PDF

Triple Negative Breast Cancer in People of North East India: Critical Insights Gained at a Regional Cancer Centre

  • Sharma, Mousumi;Sharma, Jagannath Dev;Sarma, Anupam;Ahmed, Shiraj;Kataki, Amal Chandra;Saxena, Rahul;Sharma, Dilutpal
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.15 no.11
    • /
    • pp.4507-4511
    • /
    • 2014
  • Background: Breast cancer is a heterogeneous disease comprising of distinct biological subtypes with many targeted prognostic biomarkers having therapeutic implications. However, no specific targeted therapy for triple negative breast cancer has been discovered to date and hence further research is needed. Aim: The aim and objectives of the present study were to examine the prevalence of triple negative breast cancer (TNBC) in North-East India and to compare the clinicopathological parameters in two study groups defined by immunohistochemistry (IHC) - "TNBC" and "Others". Materials and Methods: We carried out a retrospective study in a cohort of 972 patients diagnosed with invasive breast carcinoma in the Department of Pathology, Dr. B. Borooah Cancer Institute, a Regional Cancer Centre for treatment and research, Guwahati, for a period of 3 years and 10 months from January 2010 to October 2013. Based on IHC findings, patients were divided into two groups - "TNBC" and "Others". All relevant clinicopathological parameters were compared in both. TNBC were defined as those that were estrogen receptor (ER), progesterone receptor (PR), and HER2/neu negative while those positive for any of these markers were defined as "Others". Results: In this study, out of total 972 cases 31.9% (310 cases) were defined as TNBC and 662 cases (68.1%) as "Others" based on IHC markers. Compared to the "Others" category, TNBC presented at an early age (mean 40 years), were associated with high grade large tumours and high rate of node positivity, IDC NOS being the most common histological subtype in TNBC. Conclusions: TNBC accounts for a significant portion of breast cancers in this part of India and commonly present at younger age and tend to be large high grade tumours.

Photo-Induced Scalar Phenomena according to Thickness Dependence of Chalcogenide $As_{40}Ge_{10}Se_{15}S_{35}$ Thin Film (칼코게나이트 $As_{40}Ge_{10}Se_{15}S_{35}$ 박막에서 두께에 따른 광유기 스칼라 현상)

  • 이현용;박수호;정홍배
    • Electrical & Electronic Materials
    • /
    • v.10 no.5
    • /
    • pp.467-472
    • /
    • 1997
  • In this study, we investigated the thickness dependence of thermal bleaching(TB) effect as well as photo-induced scalar phenomena, such as photodrakening(PD) effect and photorefraction(PR) change, in chalcogenide A $s_{40}$ G $e_{10}$S $e_{15}$ $S_{35}$ thin films. We found that when these films were exposed for 15 minutes using blue-pass filtered Hg lamp(~4300$\AA$) after annealing for 30 minutes around the glass transition temperature Tg(20$0^{\circ}C$), the refractive index change ($\Delta$n) was varied up to 0.02~0.46 according to each thickness condition and the optical energy gap ($\Delta$ $E_{op}$ ) was shifted to a longer wavelength of approximately 0.67eV, especially for 1000$\AA$-thickness. Also, the TB PD effects have been understood by the results related to optical absorption characteristics. The TB effect could be estimated as increasing the stabilization of amorphous chalcogenide films since absorption slope of extended regions(U) was not changed by annealing. On the other hand, the PD effect could be understood as due to the enhancement of disorder since U and the slope of Urbachs tail(1/F) around an absorption edge were decreased by exposing.ing.n edge were decreased by exposing.

  • PDF

A Study on the Perception of English Rhythm and Intonation Structure by Korea University Students (대학생의 영어 리듬과 억양구조 인식에 대한 연구)

  • Park Joo-Hyun
    • Proceedings of the KSPS conference
    • /
    • 1997.07a
    • /
    • pp.92-114
    • /
    • 1997
  • This study is aimed to grasp the actual problems of the perception of English rhythm and intonation structure by Korean University students who have studied English in the secondary schools for the past six years, and to establish the systems of English rhythm and intonation structure for the Korean students of English. For this study, the listening test is provided, and 100 students are chosen as the subjects of the study. The noticeable findings are summarized as follows: (1) Koreans perceive the words stress comparatively well in nonsense words, unfamiliar place names, and familiar word. (2) Koreans do not perceive the isochrony of English rhythm well enough. The perception of the sentence stress is very unstable, especially in the sentence involved in polysyllabic words, compound words, and 'emphatic stress' pr 'contrastive stress'(or in the different rhythmic patterns). (3) Koreans do not perceive the nucleus well enough. The perception of the nucleus is more stable in content words than in function words, at the end of a sentence than in the middle of a sentence, and in monosyllabic words than in the polysyllabic words. (4) Koreans do not perceive the boundary(or pause) of intonation group well enough. The perception of the pause is unstable in the long or complex sentence. (5) Koreans discriminate the meaning of English word stress comparatively well, especially in disyllabic words. But the discrimination is somewhat unstable in polysyllabic words and between 'adjective' and 'verb' (6) Koreans' discrimination of the intonation meaning is below the level. Koreans do not perceive the differences of intonation meaning according to the pitch accent or the focus. In conclusion, the writer will propose the procedures for the teaching of rhythm and intonation in the following order: word stress drill longrightarrowstressed and reduced syllables drilllongrightarrowrhythm group drilllongrightarrowthe varying rhythm drilllongrightarrowsentence stress drilllongrightarrownucleus drill longrightarrowintonation group drilllongrightarrowlong utterance drill of more than two intonation group.

  • PDF

The Chinese express opinion and concept of 'face' (중국인의 의견표명 행위와 체면관)

  • Ju, Min-Uk
    • Korean journal of communication and information
    • /
    • v.62
    • /
    • pp.74-94
    • /
    • 2013
  • The purpose of the thesis is to find out the correlation between Chinese 'Personal Opinion Expression on Offline' and 'Personal Opinion Expression on Online'(Hypothesis 1) and between 'Save Face' and 'Personal Opinion Expression on Offline', 'Personal Opinion Expression on Online'(Hypothesis 2). It also analyzes and verifies the impact of 'Save Face' among 'Personal Opinion Expression on Offline', and 'Personal Opinion Expression on Online'(Hypothesis 3). The results of this study shows that correlation between 'behavior of opinion expression on Offline' and 'behavior of opinion expression on Online'. Chinese people who express their views in the public, tend to express their opinions on the Online. The thesis also covers that 'Silence' can be caused not only by 'Personal Fear of Isolation', but also by 'Save Face' upon 'The Spiral of Silence a Theory' by Elisabeth Noelle-Neumann, and prove that 'Save Face' relatively affects 'People talk about their observation'. It also confirms that 'Save Face in Open Space', a factor of 'Save Face's, performs a partial channel on 'Personal Opinion Expression on Online' and 'Personal Opinion Expression on Offline'.

  • PDF

Shared Value Expectation on Lifelong Education (평생교육에 대한 공유기대가치 연구)

  • Kim, Chul-Ho
    • Journal of Digital Convergence
    • /
    • v.13 no.12
    • /
    • pp.325-336
    • /
    • 2015
  • The purpose of this study is to confirm the components of users' shared value expectation(SVE) on lifelong education through convergent approaches. After reviewing primary data and collecting secondary data with quantitative and qualitative research methodologies, the components of users' SVE on lifelong education were categorized into 10 perspectives, 27 measured variables, and 81 questions. After conducting a confirmatory factor analysis, the latent measurement model was confirmed as reasonable. Internal reliability, construct convergent discriminant validity were also confirmed as reasonable. In a viewpoint that builds interdisciplinary theory, this research may help grasp users' SVE on lifelong education with interdisciplinary approaches. In a strategic viewpoint, this study may contribute to both understanding categorized users' value expectation and planning/executing suitable programs that can meet the expectations. In a managerial viewpoint, this result may help measure the effectiveness of SVE on lifelong education quantitatively.

The Characteristics of Identical Color Coordination In Contemporary Women's Fashion - Centered on the Collections of Paris, Milan, New York, London - (현대(現代) 여성(女性) 패션에 나타난 동일색채(同一色彩) 코디네이션의 특성(特性) - 파리, 밀란, 뉴욕, 런던 컬렉션 중심(中心)으로 -)

  • Kwon, Hae-Sook
    • Journal of Fashion Business
    • /
    • v.9 no.1
    • /
    • pp.21-33
    • /
    • 2005
  • The main objective of this research was to understand the characteristics of identical color coordination through the analysis of modern female fashion color coordination as they appear in the 'Collections'. Data collection of 2026 was done through review of '$pr\hat{e}t-\grave{a}$-porter Collections' of four cities; Milan, London, New York, Paris. Lastly, statistical analysis of frequency and $X^2$-test and also qualitative interpretation of identical color coordination characteristics were completed. The main findings were; The color coordination of modern women's fashion produces a unified theme, or monochromatic harmony, through the use and coordination of identical colors. The clear contrast of tones portrays a strong image especially in achromatic color coordination, and through the use of texture variation, monochromatic color coordination becomes even more compelling. The tone variation, observed most often in monochromatic color coordination was the black and white contrast, which enhances the simplicity and clarity. Within chromatic color combinations, tone on tone color coordination was achieved by varying brightness. Furthermore, the observation of Faux Camaeu indicates that the coordination of different textures is used often in identical color coordination. While achromatic colors can lead to a hard and rough feeling, it also is compensated through the use of varying textures. In addition, adding variety of textures can add subtle interests to the simplicity of white. Lastly, in all four collections, the chromatic identical color coordination was found more frequently than the achromatic. In Paris, N.Y. & London, the chromatic identical coordination was used more often than chromatic. Milan showed most use of achromatic coordination. The use of the tones showed similar trends in all four collections, with contrasting tone being used most often, followed by similar and identical tones.

Nanocomposite Magnetic Materials

  • Ludwig Schultz;Alberto Bollero;Axel Handstein;Dietrich Hinz;Karl-Hartmut Muller;Golden Kumar;Juergen Eckert;Oliver Gutfleisch;Anke Kirehner Aru Yan
    • Journal of Powder Materials
    • /
    • v.9 no.6
    • /
    • pp.381-393
    • /
    • 2002
  • Recent developments in nanocrystalline and nanocomposite rare earth-transition metal magnets are reviewed and emphasis is placed on research work at IFW Dresden. Principal synthesis methods include high energy ball milling, melt spinning, mold casting and hydrogen assisted methods such as reactive milling and hydrogenation-disproportionation-desorption-recombination. These techniques are applied to NdFeB-, PrFeB- and SmCo-type systems with the aim to produce high remanence magnets with high coercivity. Concepts of maximizing the energy density in nanostructured magnets by either inducing a texture via anisotropic HDDR or hot deformation or enhancing the remanence via magnetic exchange coupling are evaluated. With respect to high temperature applications melt spun $Sm(Co_{0.74}Fe_{0.1}Cu_{0.12}Zr_{0.04})_{7.5}$ ribbons were prepared, which showed coercivities of up to 0.53 T at 50$0^{\circ}C$. Partially amorphous $Nd_{60}Fe_xCo_{30-x}Al_{10}(0{\leq}x{\leq}30)$ alloys were prepared by copper mold casting. The effect of transition metal content on the glass-forming ability and the magnetic properties was investigated. The $Nd_{60}Co_{30}Al_{10}$ alloy exhibits an amorphous structure shown by the corresponding diffraction pattern. A small substitution of Co by 2.5 at.% Fe results In the formation of Fe-rich crystallites embedded in the Nd-rich amorphous matrix. The Fe-rich crystallites show hard magnetic behaviour at room temperature with a coercivity value of about 0.4 T, relatively low saturation magnetization and a Curie temperature of 500 K.

A Comparison of Legibility Based on Illumination Intensity and Contrast Ratio in Displays (디스플레이에서 조도와 대비비에 따른 가독성 비교 연구)

  • Hong, Ji-Young;Min, Jang-Geun
    • The Journal of the Institute of Internet, Broadcasting and Communication
    • /
    • v.17 no.4
    • /
    • pp.71-76
    • /
    • 2017
  • Visual perception is part of a field of study that examines the analysis and recognition of objects. There have been numerous studies on this topic, including research on the physiological and cognitive aspects of the visual system. Visual perception theory was established through such research efforts and the potential for its application in each field is being investigated. Mobile displays are a representative example of media in the new age. Therefore, this study is based on the understanding that research on visual perception must stress the importance of useful visual cognition. This study used displays to conduct legibility tests based on illumination intensity and contrast ratio. Two conditions relevant to legibility were tested 1) illumination intensity environment and 2) two luminance conditions proposed as measures to improve readability in existing mobile displays. The results of this study were analysed to determine the degree of legibility based on illumination intensity and contrast ratio, and measures for improving legibility were proposed.