• 대한약리학회지
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• 제32권2호
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• pp.269-281
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• 1996

Pharmacokinetics of prednisolone and prednisone undergoing reversible interconversion were analyzed from the model including this metabolic process. Blood samples were drawn serially upto 12 hours after I,V. bolus injection of 1 mg/kg prednisolone sodium phosphate and prednisone into 8 dogs as a crossover manner. Plasma concentrations of those two steroids were simultaneously measured with the method of HPLC. After injection, plasma concentrations of administered prednisolone and prednisone were declined with a biexponential pattern and their metabolic partner was rapidly formed. Plasma concentrations of those metaboite were decayed in parallel with their parent steroids throught the elimination phase. Apparent clearances of prednisolone and prednisone were $11.1{\pm}2.0\;ml/min/kg$ and $45.9{\pm}6.4\;ml/min/kg$, and they were underestimated by 29.4% and 33.6% compared to their real clearances$(15.7{\pm}4.4\;and\;69.2{\pm}17.7\;ml/min/kg)$ estimated using reversible interconversion model. Apparent volume of distribution of prednisolone$(1.32{\pm}0.43\;L/kg)$ and prednisone$(4.81{\pm}2.75\;L/kg)$ were overestimated by 53.5 and 52.7% and were compared to the real volumes $(0.86{\pm}0.30\;and\;3.15{\pm}2.13\;L/kg)$. Mean residence time of prednisolone$(2.0{\pm}0.61\;h)$ and prednisone$(1.74{\pm}0.74\;h)$ were much longer than the real sojourn time$(0.93{\pm}0.26\;and\;0.88{\pm}0.54\;h)$. Essential clearances In the reversible interconversion were greater as following orders: $Cl_{21}$(44.3 ml/min/kg) > $Cl_{20}$(24.2 ml/min/kg) > $Cl_{12}$ (7.9 ml/min/kg) > $Cl_{10}$(7.8 ml/min/kg). Estimated mean values of RF, EE, $%X^1_{ss}$ and $RHO^2_1$ were $0.31{\pm}0.10$, $1.49{\pm}0.23$, $69.3{\pm}16.7%$ and $0.65{\pm}0.10$, respectively. These results suggested that true pharmacokinetic parameters estimated from the model including reversible interconversion were significantly different from the apparent parameters estimated from the conventional mamillary model, and disposition of these two steroids seemed to be well explained by the model including reversible interconversion.

• 한국지구과학회지
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• 제22권6호
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• pp.500-511
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• 2001

양산단층이 지나는 한국 남동지방 지각의 Q$_P^{-1}$ 및 Q$_S^{-1}$를 한국자원연구소가 설치한 9점의 지진관측소 자료를 바탕으로 확장 Coda 규격화법을 이용하여 구하였다 1994년 12월부터 2000년 2월에 일어난 근지지진에서 707개 지진기록에 대하여 1${\sim}$2, 2${\sim}$4, 4${\sim}$8, 8${\sim}$16및 16${\sim}$32Hz의 대역필터를 적용하여 분석한 결과, 각 관측점의 Q$_P^{-1}$는 (7${\pm}$2)${\times}$10$^{-3}$에서 (5${\pm}$4)${\times}$10$^{-4}$으로, Q$_S^{-1}$는 5${\pm}$4)${\times}$10$^{-4}$에서 (5${\pm}$2)${\times}$10$^{-4}$로 주파수가 1.5Hz에서 24Hz로 늘어남에 따라 줄어드는 주파수 의존성이 보인다. 이들 값의 지수 회귀선은 Q$_P^{-1}$가 0.009(${\pm}$0.003)f$^{-1.05({\pm}0.14)$, Q$_S^{-1}$가 0.004(${\pm}$0.001)f$^{-0.75({\pm}0.14)$)이다.

• Journal of Yeungnam Medical Science
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• 제24권2호
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• pp.197-205
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• 2007

Background : The occurrence of atrial fibrillation after ablation of atrial flutter is clinically important. We investigated variables predicting this evolution in ablated patients without a previous atrial fibrillation history. Materials and Methods : Thirty-six patients (Male=28) who were diagnosed as atrial flutter without previous atrial fibrillation history were enrolled in this study. Group 1 (n=11) was defined as those who developed atrial fibrillation after atrial flutter ablation during 1 year follow-up. Group 2 (n=25) was defined as those who has not occurred atrial fibrillation during same follow-up term. Echocardiogram was performed to all patients. We measured left atrial size, left ventricle end diastolic and systolic dimension, ejection fraction and left atrial volume index before and after ablation of atrial flutter. The differences of each variables were compared and analyzed between two groups. Results : The preablation left ventricular ejection fraction (preLVEF) and postablation left ventricular ejection fraction (postLVEF) are $54{\pm}14%$, $56{\pm}13%$ in group 1 and $47{\pm}16%$, $52{\pm}13%$ in group 2. The differences between each two groups are statistically insignificant ($2.2{\pm}1.5$ in group 1 vs $5.4{\pm}9.8$ in group 2, p=0.53). The preablation left atrial size (preLA) and postablation left atrial size (postLA) are $40{\pm}4mm$, $41{\pm}4mm$ in group1 and $44{\pm}8mm$, $41{\pm}4mm$ in group 2. The atrial sizes of both groups were increased but, the differences of left atrial size between two groups before and after flutter ablation were statistically insignificant ($0.6{\pm}0.9mm$ in group 1 vs $-3.8{\pm}7.4mm$ in group 2, p=0.149). The left atrial volume index before flutter ablation was significantly reduced in group 1 than group 2 ($32{\pm}10mm^3/m^2$, $35{\pm}10mm^3/m^2$ in group 1 and $32{\pm}10mm^3/m^2$, $29{\pm}8mm^3/m^2$ in group 2, p<0.05). Conclusion : The difference between left atrial volume index before and after atrial flutter ablation is the robust predictor of occurrence of atrial fibrillation after atrial flutter ablation without previous atrial fibrillation.

• 대한정형도수물리치료학회지
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• 제12권2호
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• pp.21-25
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• 2006

Objective: The purposes of this study are to provide fundamental data and a rehabilitation program in physical therapy. It has been operated by 30 male college students for lumbar isokinetic exercises. Method : Subjects have been carried out in an experiment by Biodex system operating isokinetic torso rotation. This performance was activated by left rotation after right rotation repeatedly. Results: 1. The mean peak torques at $60^{\circ}$/sec were $95.6{\pm}20.62$ (Rt) and $93.84{\pm}18.41$ (Lt). 2. The mean peak torques/body weight at $60^{\circ}$/sec were $69.28{\pm}28.31$ (Rt) and $67.07{\pm}27.04$ (Lt). 3. The total works in right side at $60^{\circ}$/sec and $180^{\circ}$/sec were $492.21{\pm}92.37$, $1294.97{\pm}278.96$ and in left side at $60^{\circ}$/sec and $180^{\circ}$/sec were $515.78{\pm}109.47$, $1443.74{\pm}329.67$. 4. The work to body weight ratio at $60^{\circ}$/sec was $78.30{\pm}32.37$ (Rt) and $79.93{\pm}37.30$ (Lt). 5. The average powers in right side at $60^{\circ}$/sec and $180^{\circ}$/sec were $76.75{\pm}16.69$, $117.19{\pm}29.94$ and in left side at $60^{\circ}$/sec and $180^{\circ}$/sec were $78.54{\pm}18.58$, $125.39{\pm}32.90$. 6. The work fatigue at $180^{\circ}$/sec was $21.76{\pm}14.82$ (Rt) and $19.66{\pm}26.23$ (Lt). Conclusion: In right side and left side, there was no significant difference in peak torque. peak torque/body weight, work to body-weight ratio, average power of trunk rotators at $60^{\circ}$/sec(p<0.05). However there was a significant difference in the total work of trunk rotators at $60^{\circ}$/sec(p>0.05). Also there was a significant difference in the average of trunk rotators at $180^{\circ}$/sec(p>0.05).

• 한국전자통신학회논문지
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• 제7권6호
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• pp.1529-1536
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• 2012

이 연구의 목적은 파크골프 운동이 신체구성 및 수면에 어떠한 영향을 미치는지를 규명하는데 있다. 신체구성 측정은 다주파수임피던스측정기(Inbody720)를 이용하여 Weight, %BodyFat, BMI, WHR을 측정하였으며, 수면은 오진주 등(1998)의 수면측정도구로 측정하였다. 신체구성의 변화를 보면 실험군 집단에서 실험 전 체중 $60.56{\pm}6.25kg$, BMI $25.40{\pm}12.4kg/m^2$, %BodyFat$36.46{\pm}4.67%$, WHR $0.93{\pm}0.17$에서 12주후 체중 $58.3{\pm}7.16kg$, BMI $24.28{\pm}2.32kg/m^2$, %BodyFat $35.1{\pm}3.02%$, WHR $0.92{\pm}0.16$으로 유의한 감소(p<.05)가 나타났고, 수면점수의 변화를 살펴보면 운동프로그램 실시 후 실험군의 수면점수는 42.03에서 47.43으로 5.37증가하였고 대조군은 42.48에서 43.4로 0.94 증가하였으며 두 집단 간에 통계적으로 유의한 차이가 있었다. 이 연구에서 수행한 12주간의 파크골프운동은 노인의 신체구성과 수면에 긍정적인 영향을 미치는 것으로 나타났다.

• 한국조리학회지
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• 제17권5호
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• pp.184-192
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• 2011

본 연구에서는 시판용 멥쌀가루에 약리효과와 착색성이 뛰어난 강황분말을 0~2.4% 첨가하여 설기떡을 제조한 후 수분함량, 색도, 텍스처, 관능 검사를 실시하여 최적의 배합비를 통해 기호성이 좋은 강황분말을 첨가한 설기떡의 보급화를 위한 기초자료를 제공하고자 한다. 일반성분은 수분함량 $12.6{\pm}0.21%$, 단백질 $1.8{\pm}0.12%$, 지방 $1.0{\pm}0.00%$, 회분 $1.3{\pm}0.01%$였으며, 시판용 쌀가루의 일반성분은 수분�t량 $11.7{\pm}0.17%$, 단백질 $7.6{\pm}0.32%$, 지방 $2.1{\pm}0.01%$, 회분 $1.6{\pm}0.01%$였다. L값은 강황분말 첨가량에 따라 유의적으로 감소하였으며, a값와 b값은 강황분말 첨가량에 따라 유의적으로 증가하였다. 텍스쳐 특성은 hardness의 경우 첨가량이 증가할수록 유의적으로 증가하였으며 gumminess, cohesiveness, chewiness는 강황분말 첨가량에 따라 유의적인 차이가 없었다(p<0.05). 강황분말 첨가 설기떡의 관능적 특성에서는 강황분말 0.8% 첨가한 경우가 색과 향, 촉촉함, 씹힘성에서 대조구와 유의적인 차이를 보였으며 가장 높게 평가되었다.

• 한국습지학회지
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• 제12권1호
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• pp.41-49
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• 2010

거미의 건축행동은 유전적 요인의 제한을 받지만 서식지의 다양한 환경 요인을 반영하는 먹이 사냥을 위한 투자 행동이며, 능동적인 의사결정의 반영이다. 본 연구는 긴호랑거미(Argiope bruennichi)를 대상으로 나대지 ('dry field')와 논습지('wet field')에 서식하는 개체가 건축한 웹의 물리적 구조를 정량적으로 측정 비교하였다. 습도 46.4%인 나대지(인천시 천마산)에서 35개체, 습도 73.9%의 논습지(충남 태안군)에서 13개체의 웹 구조가 분석되었다. 상대적으로 습도가 낮고 초본이 우거진 나대지 환경에 건축하는 개체의 경우 논습지 환경과 비교해 더 많은 거미실을 투자해($32.5{\pm}12.8$ vs. $16.9{\pm}5.4$ 개의 나선실 사용), 더 넓은 웹을 건축하였다($976{\pm}643cm^2$ vs. $532{\pm}254cm^2$). 또한 나대지에 서식하는 개체가 논습지 개체에 비해 더 높은 웹을 건축하는 것으로 나타났다($71.4{\pm}39.6cm$ vs. $49.6{\pm}31.2cm$). 흰띠줄 건축행동을 측정한 결과 나대지의 개체가 상대적으로 큰 흰띠줄을 건축하는 것으로 나타났다($18.8{\pm}3.4cm$ vs. $3.9{\pm}3.2cm$). 웹의 기울기를 측정한 수직경사와 동서경사의 경우 나대지와 논습지에서 유의미한 차이를 보이지 않았다. 본 연구 결과는 성체 암컷 긴호랑거미가 환경 요인에 따라 건축행동을 변화시킬 수 있다는 것을 시사한다

• 한국가금학회:학술대회논문집
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• 한국가금학회 2004년도 제21차 정기총회 및 학술발표회
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• pp.99-100
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• 2004

한국 재래닭의 각 계통별 세대간 계란의 장경, 단경 및 난형지수는 각각 53.0$\pm$0.6~55.6$\pm$0.8 mm, 39.1$\pm$0.8~40.9$\pm$0.2 mm 및 72.7$\pm$1.5~75.9$\pm$0.5이었고 회귀방정식에 의한 회귀계수로 표현된 능력변화 추세를 보면 적갈색, 황갈색, 회갈색, 흑색 및 백색 계통의 계란 장경은 각각 -0.01, 0.20, -0.02, -0.01 및 0.03 mm, 단경은 각각 0.10, 0.48, 0.52, 0.25 및 0.25 mm, 난형지수는 0.19, 0.62, 1.00, 0.32 및 0.33이었다.

• Journal of Chest Surgery
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• 제28권5호
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• pp.471-474
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• 1995

A total of 20 patients underwent bullectomy in the spontaneous pneumothorax between October 1993 and August 1994. The patients were divided into two groups: Control group; the patients who received with mid-axillary approach[n=10 , Experimental group; the patients who received with video-assisted thoracic surgery [n = 10 . The results were as follows; 1. The total sex distribution was male predominence [M :F=6:1 . Mean age of control group was 31.6$\pm$ 10.1 age and experimental group was 24.3$\pm$ 5.5 age. 2. The operative times were 117.0 $\pm$ 32.6min in control group and 102.5$\pm$ 38.4min in experimental group [not significant . 3. The indwelling period of postoperative chest tube and hospital stay were 4.5$\pm$ 2.6 days and 8.3 $\pm$ 1.8 days in control group, $1.5\pm$ 0.5 days and 3.1 $\pm$ 0.3 days in experimental group[p=0.0018, < 0.0001 . 4. In control group, injection times of pain-killer were 1.7$\pm$ 0.7 times/day at operative day and 0.4$\pm$ 0.6times/day at postoperative 1 day. In experimental group, there were 0.3$\pm$ 0.7times/day at operative day and 0.1 $\pm$ 0.3times/day at postoperative 1 day[p=O.O002 at operative day, not significant at postoperative 1 day .

• 한국치위생학회지
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• 제10권1호
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• pp.173-183
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• 2010

Objectives : The purpose of this study was to provide basic materials for defining educational direction of dental hygiene department and establishing the instruction to improve direction consulting and academic effect of dental hygiene department student. Methods : The researcher surveyed the relation among job aptitude, academic ability and academic performance by selecting 131 dental hygiene department students of P university as study targets. Results : For high school classifications, direction searches and academic abilities of dental hygiene department students of P university, it was found that classical high school was 68.7% and vocational high school was 31.3%. For job aptitude, social type was 58.0% and artistic type was 26.0% so they were usual. For academic ability, interpersonal relation($12.78{\pm}1.34$), music/rhythm was($12.32{\pm}1.09$) and natural($12.32{\pm}1.00$) showed high scores in order over the first, the second and the third field and language/vocabulary(22.6%) and music/rhythm(21.6%) was the next. For academic performance depending on high school classification, job aptitude and academic ability, there was a significant difference in high school classification by classical high school($86.55{\pm}8.21$) and vocational high school($85.34{\pm}11.31$)(p<0.05) and there was also a significant difference in job aptitude by social type($85.45{\pm}9.42$) and artistic type($88.41{\pm}6.93$)(p<0.05). In the mutual relation between academic ability and academic performance, the high academic ability score in the first field was led to the high score in the second and the third field, showing significant mutual relation(p<0.00). Conclusions : This research has been accomplished by college students of dental hygeine department, so you have to consider before generalizing these results. Therefore it is required to research more, likewise using a comparison with other students or it should be conducted by general people.