• 제목/요약/키워드: PHYSIOLOGICAL RESPONSE

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Effects of Morphine on Somatosyrnpathetic Reflex and Arterial Blood Pressure Response Evoked by Stimulation of Peripheral Nerves

  • Huh, Min-Gang;Yan, Hai-Dun;Lim, Won-Il;Kim, Jun
    • The Korean Journal of Physiology
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    • v.29 no.2
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    • pp.309-321
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    • 1995
  • In the present study, the relationship between the somatosympathetic reflexes and arterial blood pressure responses to electrical stimulation of the peripheral nerve was investigated in cats anesthetized with ${\alpha}-chloralose$. Single sympathetic postganglionic fiber activities were recorded from the hindlimb muscle and skin nerves and also from the cervical and abdominal sympathetic chains. Effects of the morphine on responses of the sympathetic nerve and arterial blood pressure to activation of the peripheral $A{\delta}-$ and C-afferent nerves were analyzed. The following results were obtained. 1) Arterial blood pressure was depressed by peripheral AS-afferent stimulation (A-response) and was elevated during C-afferent activation (C-response). 2) Intravenously administered morphine enhanced the C-response while the A-response decreased insignificantly, Only the C-response was decreased by intrathecal morphine. 3) All the ten recorded cutaneous sympathetic fibers showed periodic discharge pattern similar to respiratory rhythm and five of them also showed cardiac-related rhythm. However, most of the muscular sympathetic fibers had cardiac-related rhythm and only four fibers showed respiratory rhythm. 4) Morphine decreased the sympathetic C-reflex elicited by the peripheral C-afferent activation and the abdominal sympathetic A-reflex was also decreased by morphine. From the above results, it was concluded that supraspinal mechanisms were involved in the enhanced arterial pressor response to peripheral C-afferent activation by intravenous morphine.

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Properties of the Arterial Pressor Response Induced by Stimulation of the Ventral Root Afferent Fibers in the Cat (고양이 척수 전근내 감각신경 자극으로 유발된 승압반응의 생리학적 특성)

  • Kim, Jun;Seoh, Sang-Ah;Sung, Ho-Kyung
    • The Korean Journal of Physiology
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    • v.23 no.1
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    • pp.129-138
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    • 1989
  • In an attempt to characterize the ventral root afferent fibers, arterial blood pressure responses to stimulation of the ventral root (VR) were observed in anesthetized cats. Effects of the morphine administered either intravenously or direct spinally and of the spinal lesions on the pressor responses were compared. Followings are the results obtained. 1) Stimulation of the VR with C-strength, high frequency stimuli evoked a marked pressor response. No depressor response, which had been reported during peripheral nerve stimulation, was observed during VR stimulation with low frequency. 2) Acute cervical spinalization abolished the pressor response, indicating the involvement of supraspinal mechanism. 3) The ascending spinal pathways of the pressor response were located in the dorsolateral funiculus bilaterally. 4) Intravenously administered morphine exaggerated the pressor response to VR stimulation, while direct spinally administered morphine suppressed it. From the above results it was concluded that the ventral root afferent fibers have more similar properties to muscular C-afferent fibers than to cutaneous C-fibers.

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Optimization of Response Characteristics of pH-ISFET Glucose Sensor (완충용액과 효소고정화막의 조성에 따른 pH-ISFET 포도당센서의 감응특성)

  • Lee, Heung Lark;Yang, Seung Tae;Jung, Doog Sook;Kim, Chang Soo;Sohn, Byung Ki
    • Analytical Science and Technology
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    • v.5 no.2
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    • pp.177-184
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    • 1992
  • A preparation method and response characteristics of a glucose sensor which consisted of pH-ISFET and glucose oxidase-immobilized membrane were investigated. The pH-ISFET glucose sensor was fabricated by immbilizing bovine serum albumin and glucose oxidase with glutaraldehyde on gate of the pH-ISFET. Effects of pH and concentration of working buffer and enzyme load on the pontentiometric response of the pH-ISFET glucose sensor were examined. Response characteristics for the determination of glucose in synthetic physiological saline solution(pH 7.4) were as follows. That is the concentration range of linear response, slope of linear response(sensitivity), and response time were $1.0{\times}10^{-4}{\sim}6.0{\times}10^{-3}M $, 4.1 mV/decade, and 12~15 min., respectively.

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Response Characteristics of pH-ISFET Urea Sensor (pH-ISFET 요소센서의 감응특성)

  • Heung Lark Lee;Seung Tae Yang;Jong Hoon Yun;Chang Soo Kim;Byung Ki Sohn
    • Journal of the Korean Chemical Society
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    • v.36 no.6
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    • pp.864-871
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    • 1992
  • A preparation method and response characteristics of a urea sensor which consisted of pH-ISFET and urease-immobilized membrane were investigated. The pH-ISFET urea sensor was fabricated by immobilizing BSA and urease with glutaraldehyde on gate of the pH-ISFET. Effects of pH and concentration of working buffer and enzyme load on the pontentiometric response of the pH-ISFET urea sensor were examined. Response characteristics for the determination of urea in synthetic physiological saline solution (pH 7.4) were as follows. That is, the concentration range of linear response, slope of linear response (sensitivity), and response time were 5.0 ${\times}$ $10^{-4}$ ${\sim}$ 5.0 ${\times}$ $10^{-2}$M, 31.6 mV/decade and 4${\sim}$10 min, respectively.

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Safety Evaluation of Individual Intersection Considering the Bio-Response (Electroencephalography) and the Cognitive Characteristics (생체반응(뇌파)과 인지평가 특성에 의한 개별 교차로 안전성 평가에 관한 연구)

  • Namgung, Moon;Lee, Byung Joo;Seo, Im Ki
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.30 no.3D
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    • pp.231-240
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    • 2010
  • As majority of the traffic accidents in intersections is caused by human factor, a close examination is required on its contributing factors through measuring the psychological and physiological response according to the driving characteristics of the drivers and the road conditions. In this study, for the safety evaluation of individual intersection considering human factors of the drivers, electroencephalography reaction was measured utilizing cutting-edge measuring equipment and survey on drivers' cognitive characteristics in ordinary times and while driving test was conducted. The relationship between the electroencephalography response when approaching the intersection and cognitive evaluation survey data in driving test was clarified, and individual intersection safety evaluation model was built considering cognitive evaluation factor and the reaction of a bio-response electroencephalography data. As a result, I could find out that cognitive evaluation was made through the reaction of a bio-response (Electroencephalography) process because electroencephalography reaction of a bio-response showed differently by the physical characteristics of the intersection and cognitive evaluation had a difference.

Environmental stress-related gene expression and blood physiological responses in olive flounder (Paralichthys olivaceus) exposed to osmotic and thermal stress

  • Choi, Cheol-Young
    • Animal cells and systems
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    • v.14 no.1
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    • pp.17-23
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    • 2010
  • We isolated warm temperature acclimation-related protein 65-kDa (Wap65) cDNA from the liver of olive flounder and investigated the mRNA expression of Wap65 and HSP70 in olive flounder exposed to osmotic (17.5, 8.75, and 4 psu) and thermal stress (25 and $30^{\circ}C$). The mRNA expression of Wap65 and HSP70 was increased by thermal stress. The mRNA expression of HSP70 was also increased by osmotic stress, whereas no significant change in Wap65 expression was detected. These results indicate that Wap65 mRNA expression occurs specifically in response to increases in water temperature, but not in response to osmotic stress. Plasma cortisol levels were also increased by osmotic and thermal stress. We also utilized the stress hormone cortisol to examine whether Wap65 expression is thermal-stress-specific. Cortisol treatment increased HSP70 mRNA expression in vitro, but had no significant effect on Wap65 mRNA expression. Thus, thermal stress, but not osmotic stress, induces Wap65 expression.

Stress Assesment based on Bio-Signals using Random Forest Algorithm (랜덤포레스트 기법을 이용한 생체 신호 기반의 스트레스 평가 방법)

  • Lim, Taegyoon;Heo, Jeongheon;Jeong, Kyuwon;Ghim, Heirhee
    • Journal of the Korean Society of Safety
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    • v.35 no.1
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    • pp.62-69
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    • 2020
  • Most people suffer from stress during day life because modernized society is very complex and changes fast. Because stress can affect to many kind of physiological phenomena it is even considered as a disease. Therefore, it should be detected earlier, then must be released. When a person is being stressed several bio-signals such as heart rate, etc. are changed. So, those can be detected using medical electronics techniques. In this paper, stress assessment system is studied using random forest algorithm based on heart rate, RR interval and Galvanic skin response. The random forest model was trained and tested using the data set obtained from the bio-signals. It is found that the stress assessment procedure developed in this paper is very useful.