• Journal of the Earthquake Engineering Society of Korea
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• v.7 no.5
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• pp.37-46
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• 2003

Response analysis of buried pipeline subjected to permanent ground deformation(PGD) due to liquefaction is mainly executed by use of numerical analysis or semi-analytical relationship, Especially for the semi-analytical relationship considering transverse PGD, it has somewhat limited applicability : since it has different formula according to the width of PGD and does not reflect various patterns of PGD which is caused by the decrease of soil stiffness, Therefore, in this study, the applicability of existing analytical relationship is closely investigated through the comparison of FEM results at first. And then, based on meaningful contemplation, improved analytical relationship is proposed. The proposed one models the system behavior of buried pipeline as the combination of cable and beam, and thus it is applicable to arbitrary width of PGD, Moreover, it does reflect various patterns of PGD by introducing interaction pattern coefficient. Through the comparison of numerical results using the FEM and the proposed analytical relationship, rational applicability is objectively verified and noticeable considerations are discussed, Moreover, analyses considering the change of PGD magnitude and patterns are performed.

• Clinical and Experimental Reproductive Medicine
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• v.32 no.1
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• pp.17-26
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• 2005

Objective: Preimplantation genetic diagnosis (PGD) is reserved for couples with a risk of transmitting a serious and incurable disease, and hence avoids the undesirable therapeutic abortion. In this study, we evaluated the efficacy of PGD for Duchenne muscular dystrophy (DMD) cases by the fluorescent PCR with polymorphic linked markers and the conventional duplex-nested PCR methods. Methods: Biopsy of one or two blastomeres was done from the embryos fertilized by ICSI on the third day after fertilization. We performed two cases of PGD-DMD by the duplex-nested PCR for the causative mutation loci and the SRY gene on Y chromosome. The triplex fluorescent PCR for the mutation loci, the SRY gene and the polymorphic microsatellite marker on X chromosome was applied for two cases of PGD-DMD. Results: By the duplex-nested PCR, successful diagnosis rate was 95.5% (21/22), but we could not discriminate the female embryos whether normal or carrier in this X-linked recessive disease. However, the triplex fluorescent PCR method showed 100% (27/27) of successful diagnosis rate, and all female embryos (n=17) were distinguished normal (n=10) from carrier (n=7) embryos. Unaffected and normal embryos were transferred into mother's uterus after diagnosis. A healthy normal male was achieved after PGD with the duplex-nested PCR method and a twin, a male and a female, were delivered with triplex fluorescent PCR method. The normality of dystrophin gene was confirmed by amniocentesis and postnatal genetic analysis in all offsprings. Conclusion: The fluorescent PCR with polymorphic marker might be useful in improving the specificity and reliability of PGD for single gene disorders.

• Parasites, Hosts and Diseases
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• v.48 no.1
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• pp.15-21
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• 2010

Astrocytes are the most abundant cells in the central nervous system that play roles in maintaining the blood-brain-barrier and in neural injury, including cerebral malaria, a severe complication of Plasmodium falciparum infection. Prostaglandin (PG) $D_2$ is abundantly produced in the brain and regulates the sleep response. Moreover, $PGD_2$ is a potential factor derived from P. falciparum within erythrocytes. Heme oxygenase-1 (HO-1) is catalyzing enzyme in heme breakdown process to release iron, carbon monoxide, and biliverdin/bilirubin, and may influence iron supply to the P. falciparum parasites. Here, we showed that treatment of a human astrocyte cell line, CCF-STTG1, with $PGD_2$ significantly increased the expression levels of HO-1 mRNA by RT-PCR. Western blot analysis showed that $PGD_2$ treatment increased the level of HO-1 protein, in a dose- and time-dependent manner. Thus, $PGD_2$ may be involved in the pathogenesis of cerebral malaria by inducing HO-1 expression in malaria patients.

• Journal of the Earthquake Engineering Society of Korea
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• v.7 no.3
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• pp.57-67
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• 2003

Response analysis of buried pipeline subjected to permanent ground deformation(PGD) due to liquefaction is mainly executed by use of numerical analysis or semi-analytical relationship, When applying these methods, so called interfacial pipelineㆍsoil interaction force plays an dominant part. Currently used interaction force is mode up of indispensable mechanical and physical components for the response analysis of buried pipeline. However, it has somewhat limited applicability to the liquefied region since it is based on the experimental results for the non-liquefied region. Therefore, in this study, improved type of pipelineㆍsoil interaction force is proposed based on the existing interaction force and experimental research accomplishments. Above all, proposed interaction force includes various patterns of PGD or spatial distributions of interaction force caused by the decrease of soil stiffness. Through the comparison of numerical results using the proposed and the existing interaction force, relative influences of interaction force on the response of pipeline are evaluated and noticeable considerations in the application of semi-analytical relationship are discussed. Moreover, analyses due to the change of pipe thickness and burial depth are performed.

• Proceedings of the Earthquake Engineering Society of Korea Conference
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• 2005.03a
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• pp.102-109
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• 2005

In this study, a prototype model of earthquake loss estimation method will be proposed for the quantitative and qualitative damage evaluation of buried pipeline subjected to Permanent Ground Deformation(PGD) due to liquefaction. With this objective, domestic and foreign status of the arts related with earthquake loss estimation method is summarized at first. Domestic development of computer aided earthquake loss estimation method seems to be difficult for the time being. Thus, referring to HAZUS : Earthquake Loss Estimation Methodology which is developed by FEMA (Federal Emergency Management Agency) and NIBS (National Institute of Building Sciences), earthquake loss estimation procedure of buried pipeline subjected to PGD due to liquefaction are proposed, and then exemplary loss estimation are executed. Considering that there have been no practical earthquake loss estimation method and procedure in Korea, the research accomplishments such as above are considered to be helpful for the substantial development of earthquake loss estimation method of buried pipeline subjected to PGD due to liquefaction.

• Proceedings of the Earthquake Engineering Society of Korea Conference
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• 2003.03a
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• pp.165-173
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• 2003

In this study, the applicability of currently used pipeline.soil interaction force and previously proposed analytical relationship for the response analysis of buried pipeline subjected to transverse permanent ground deformation (PGD) due to liquefaction is evaluated. Based on meaningful contemplation, the improvement of interaction force and proposition of analytical relationship is made. Improved interaction force includes various patterns of PGD or spatial distributions of interaction force caused by the decrease of soil stiffness, and proposed relationship based on improved formula is applicable without regard to the width of PGD. Through the comparison of numerical results by use of commercial FEM program, the rational applicability of proposed relationship is objectively confirmed.

• Journal of Life Science
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• v.15 no.6 s.73
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• pp.972-978
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• 2005

The present study was carried out to investigate the blood markers of Jeju horses. The redcell cypes (blood groups) and blood protein types (biochemical polymorphisms) were tested from 102 Jeju horses by serological and electrophoretc procedure, and their phenotypes and gene frequencies were estimated. The blood group and biochemical polymorphism phenotypes observed with high frequency were $A^{af}\;(27.45\%$), $C^{a}\;(99.02\%$), $K^{-}\;(97.06\%$), $U^{a}\;(62.75\%$), $P^{b}\;(36.27\%$), $Q^{c}\;(47.06\%$), $D^{cgm/dghm}\;(13.73\%$), $D^{adn/cgm}\;(9.80\%$), $D^{ad/cgm}$\;(8.82\%$), $D^{dghm/dghm}(7.84\%$), $D^{cgm/cgm}(7.84\%$), $AL^{B}\;(48.04\%$), $GC^{F}\;(99.02\%$), $AlB^{K}\;(97.06\%$), $ES^{FI}\;(36.27\%$), $TF^{F2}\;(25.49\%$), $HB^{B1}\;(45.10\%$), and $PGD^{F}\;(86.27\%$) in Jeju horses, respectively. Alleles observed with high gene frequency were $A^{af}$ (0.3726), $A^{C}$ (0.2647), $C^{-}$ (0.5050), $K^{-}$ (0.9853), $U^{-}$ (0.6863), $P^{b}$ (0.4657), $Q^{c}$ (0.5294), $D^{cgm}$ (0.3039), $HB^{B1}$(0.6863), $PGD^{F}$ (0.9265), $AL^{B}$ (0.6912), $ALB^{K}$ (0.9852), $GC^{F}$ (0.9950), $ES^{I}$ (0.5000) and $TF^{F2}$ (0.4950) in Jeju horses, and sfecific alleles, $D^{cgm(f)}$ (0.0196), $HB^{A}$ (0.0147), $HB^{A2}$ (0.0196), $ES^{G}$ (0.0441), $ES^{H}$ (0.0098), $TF^{E}$TF'(0.0246), $TF^{H2}$ (0.0049) and $PGD^{D}$ (0.0098) were detected in Jeju horses. These preliminary results present basic information for detecting the genetic markers in Jeju horse. and developing a system for parentage verification and individuals identification in jeju horses.

• The Transactions of the Korea Information Processing Society
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• v.3 no.2
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• pp.359-368
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• 1996

This paper introduces PGD(Preprocessed Givens Downdating)and PHD(Preprocessed Hyperbolic Downdating) algorithms, wherein a multiple-row observation matrix $Z^T$ is factorized into a partial Cholesky factor Rz, such that $Z^T$ = $Q_zR_z, Q_zQ^T_z=I$, and then Rz is recursively downdated by using GD(Givens Downdating)and HD(Hyperbolic Dondating), respectively. Time complexities of PGD and PHD algorithms are $pn^2$ ＋ $5n^3/6$ 및 $pn^2$＋$n^3/3$ flops, respectively, if p$\geq$n, while those of the existing GD and HD are known to be $5pn^2/2$ and $2pn^2$ flops,, respectively. This concludes that the factorization of observation matrices, which we call preprocessing, would improve the overall performance of the downdating process. Benchmarks on the Sun SPARC/2 system also show that preprocessing would shorten the required downdating times compared to those of downdatings without preprocessing. Furthermore, benchmarks also show that PHD provides better performance than PGD.

• Journal of Internet Computing and Services
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• v.24 no.4
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• pp.25-36
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• 2023

Today, as AI (Artificial Intelligence) technology is introduced in various fields, including security, the development of technology is accelerating. However, with the development of AI technology, attack techniques that cleverly bypass malicious behavior detection are also developing. In the classification process of AI models, an Adversarial attack has emerged that induces misclassification and a decrease in reliability through fine adjustment of input values. The attacks that will appear in the future are not new attacks created by an attacker but rather a method of avoiding the detection system by slightly modifying existing attacks, such as Adversarial attacks. Developing a robust model that can respond to these malware variants is necessary. In this paper, we propose two methods of generating Adversarial attacks as efficient Adversarial attack generation techniques for improving Robustness in AI models. The proposed technique is the XAI-based attack technique using the XAI technique and the Reference based attack through the model's decision boundary search. After that, a classification model was constructed through a malicious code dataset to compare performance with the PGD attack, one of the existing Adversarial attacks. In terms of generation speed, XAI-based attack, and reference-based attack take 0.35 seconds and 0.47 seconds, respectively, compared to the existing PGD attack, which takes 20 minutes, showing a very high speed, especially in the case of reference-based attack, 97.7%, which is higher than the existing PGD attack's generation rate of 75.5%. Therefore, the proposed technique enables more efficient Adversarial attacks and is expected to contribute to research to build a robust AI model in the future.

• Journal of applied mathematics & informatics
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• v.24 no.1_2
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• pp.333-342
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• 2007

A nonsmooth PGD scheme for minimizing a nonsmooth convex function is presented. In the parallelization step of the algorithm, a method due to Pang, Han and Pangaraj (1991), [7], is employed to solve a subproblem for constructing search directions. The convergence analysis is given as well.