• Title/Summary/Keyword: PDI model

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The Variables Affecting the Fluctuation of Visitors and the Construction of Models of Demand Projection in National Park (국립공원 이용객의 변동요인과 수요예측 모형설정)

  • 정하광
    • Journal of the Korean Institute of Landscape Architecture
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    • v.19 no.2
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    • pp.12-22
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    • 1991
  • The purpose of this study is to identify demand and methods of projection, including to prove the variables affecting the fluctuation of visitors and to analyze the relationship between these variables in National Park. Statistical analysis method (Multiple Linear Regression Analysis, ANOVA, and Model diagnostics) was carried out by computer program SAS/pc. 13 variables (1. Total Population, 2. Per Capita PDI, 3. Employment Ratio of S.O.C. & others, 4. NO. of Passenger Car, 5. Length of Roads, 6. Leisure Expenditure of Farm Household, 7. Leisure Expenditure of Urban Household, 8. Price Index, 9. NO. of Bus, 10. Exchange on Dollars, 11. Export, 12. Import, and 13. Visitors in National Park) had been used to this study. The scope of time period is during the last 17 years (1970-1986). The results were as follows; 1) Participation depends only on the specific characteristics of the economic factors (Price Index and Leisure Expenditure of Urban Household). These factors are the importance factors directly affecting the participation of visitors. The statistical Model for projecting the visitors in National Parks is the function of "Visitors in National Parks (thousand)=14915+0.210311*Leisure Expenditure of Urband Household (won)-157.835619*Price Index(1985=100)" 2) The external factors affecting the participation depends upon the interelated features of availability and accessibility (NO. of Passenger Car, Length of Roads, and NO. of Bus) of recreation resources or sites, and the economic factors (Per Capita PDI, Export, and Import). These factors are the factors indirectly affecting the participation of visitors. 3) The participation depends on the specific characteristics of demographic factors (Total Population and Employment Ratio of S.O.C. & others). These factors are the factors indirectly affecting the participation of visitors. 4) The unexpected fluctuation of yearly visitors depends on oil shock or inflation (1971, 1973-1974, 1979-1980), promulgation of national emergency decrees (1971-1972, 1974-1975, 1979-1980), and national events (assassination of president Park's wife, Madame Yuk in 1974 and president Park I 1979).

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Requirement Analysis of Navigation System for Lunar Lander According to Mission Conditions (임무조건에 따른 달 착륙선 항법시스템 요구성능 분석)

  • Park, Young Bum;Park, Chan Gook;Kwon, Jae Wook;Rew, Dong Young
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.45 no.9
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    • pp.734-745
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    • 2017
  • The navigation system of lunar lander are composed of various navigation sensors which have a complementary characteristics such as inertial measurement unit, star tracker, altimeter, velocimeter, and camera for terrain relative navigation to achieve the precision and autonomous navigation capability. The required performance of sensors has to be determined according to the landing scenario and mission requirement. In this paper, the specifications of navigation sensors are investigated through covariance analysis. The reference error model with 77 state vector and measurement model are derived for covariance analysis. The mission requirement is categorized as precision exploration with 90m($3{\sigma}$ ) landing accuracy and area exploration with 6km($3{\sigma}$ ), and the landing scenario is divided into PDI(Powered descent initiation) and DOI(Deorbit initiation) scenario according to the beginning of autonomous navigation. The required specifications of the navigation sensors are derived by analyzing the performance according to the sensor combination and landing scenario.

Hofstede Cultural Dimension Measuring through World Values Surveys (World Value Surveys를 활용한 Hofstede 문화차원 측정과 활용에 관한 연구)

  • Kang, Mi-Young;Kwon, Jong-Wook
    • Asia-Pacific Journal of Business
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    • v.9 no.2
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    • pp.137-152
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    • 2018
  • Hofstede cultural value model is one of the most influential model for cross-cultural studies to measure national difference. In this study, we examine that Hofstede Cultural Dimensions can be measured by World Value Surveys. Selected WVS questions for 31 measurable countries after Exploratory Factor Analysis(EFA) and Confirmatory Factor Analysis(CFA), approved valid through empirical analysis. It is applicable that Individualism values(IND) has related to 2 questionnaires including life satisfaction, Power Distance values(PDI) to 2 questionnaires about political action(Signing a petition and Joining in boycotts), Masculinity values(MAS) to 2 sexual-role questionnaires like "University is more important for a boy than for a girl", Uncertainty Avoidance values (UAI) to 3 questionnaires about confidence(Parliament, The Political parties and Justice System), Long-Term Oriented values(LTO) to 4 questionnaires including "How proud of nationality" and Indulgence versus Restraints values (IVR)to 2 questionnaires including Feeling of Happiness.

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Cloning, Expression, and Renaturation Studies of Reteplase

  • Zhao, Youchun;Ge, Wang;Kong, Young;Zhang, Changkai
    • Journal of Microbiology and Biotechnology
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    • v.13 no.6
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    • pp.989-992
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    • 2003
  • Recombinant human tissue plasminogen activator deletion mutein (Reteplase) is a clinically promising thrombolytic drug. Reteplase cDNA was subcloned into a bacteria expression system, and the resultant recombinant was biologically characterized. The Reteplase was expressed in Escherichia coli as an inclusion body, and the downstream processes of the Reteplase inclusion body included denaturation, renaturation, and purification. A protein disulfide isomerase (PDI) was used to assist the refolding of Reteplase, and it was found to increase the refolding rate from less than 2% to more than 20%. The refolded Reteplase was purified through two chromatography steps, including lysine-coupled agarose affinity chromatography and then CM-sepharose cation-exchange chomatography. The purity of r-PA was analyzed by Western bolt analysis, and N-terminal amino acid and amino acid composition analyses confirmed the end-product. Reteplase showed higher thrombolytic potency in an animal thrombus model.

Energy-saving potential of cross-flow membrane emulsification by ceramic tube membrane with inserted cross-section reducers

  • Albert, K.;Vatai, Gy.;Giorno, L.;Koris, A.
    • Membrane and Water Treatment
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    • v.7 no.3
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    • pp.175-191
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    • 2016
  • In this work, oil-in-water emulsions (O/W) were prepared successfully by membrane emulsification with $0.5{\mu}m$ pore size membrane. Sunflower oil was emulsified in aqueous Tween80 solution with a simple crossflow apparatus equipped with ceramic tube membrane. In order to increase the shear-stress near the membrane wall, a helical-shaped reducer was installed within the lumen side of the tube membrane. This method allows the reduction of continuous phase flow and the increase of dispersed phase flux, for cost effective production. Results were compared with the conventional cross-flow membrane emulsification method. Monodisperse O/W emulsions were obtained using tubular membrane with droplet size in the range $3.3-4.6{\mu}m$ corresponded to the membrane pore diameter of $0.5{\mu}m$. The final aim of this study is to obtain O/W emulsions by simple membrane emulsification method without reducer and compare the results obtained by membrane equipped with helix shaped reducer. To indicate the results statistical methods, $3^p$ type full factorial experimental designs were evaluated, using software called STATISTICA. For prediction of the flux, droplet size and PDI a mathematical model was set up which can describe well the dependent variables in the studied range, namely the run of the flux and the mean droplet diameter and the effects of operating parameters. The results suggested that polynomial model is adequate for representation of selected responses.

PLGA particles and half-shells prepared by double emulsion method: characterization and release profiles of ranitidine (이중 유제 방법으로 제조된 PLGA 미립자들과 반구체:특성과 라니티딘(ranitidine)의 방출 양상)

  • Nam, Dae-Sik;Kim, Seong-Cheol;Kang, Soo-Yong;Odonchimeg, Munkhjargal;Shim, Young-Key;Lee, Woo-Kyoung
    • Journal of Pharmaceutical Investigation
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    • v.38 no.2
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    • pp.99-104
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    • 2008
  • PLGA micro/nano particles encapsulating ranitidine as a hydrophilic model drug were prepared by the double-emulsion solvent evaporation method. Surface morphology investigation by scanning electron microscope (SEM) showed that the emulsification by sonication could produce nanoparticles, whereas microparticles were prepared using high speed homogenizer. Moreover, while nanohalf-shell structure instead of spherical nanoparticle could be produced by adding poloxamer into oil phase (MC) with PLGA 504H, the addition of poloxamer didn't change particle shape in case of PLGA 502H. On the other hand, microparticle with poloxamer had more surface pores than those without poloxamer. The size and polydispersity (PDI) of particles were determined by particle size analyzer. Effective diameters of particles were in the range of $400{\sim}800\;nm$ and $1200{\sim}3300\;nm$ in case of nanoparticles and microparticles, respectively. Encapsulation efficiencies were in the range of $1.2{\sim}2.9%$. The addition of poloxamer produced the particles with higher encapsulation efficiency. In vitro release study in phosphate buffer (pH 7.4) at $37^{\circ}C$ showed common large initial burst release. However, the relative slower release profile could be observed in case of microparticles. Poloxamer addition increased the release rate, which was thought to be related to the increased surface area of particles.

Assessing the anion type effect on the hydro-mechanical properties of smectite from macro and micro-structure aspects

  • Goodarzi, Amir R.;Akbari, Hamid R.
    • Geomechanics and Engineering
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    • v.7 no.2
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    • pp.183-200
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    • 2014
  • The expansivity of clayey soils is a complicated phenomenon which may affect the stability of geotechnical structures and geo-environmental projects. In all common factors for the monitoring of soil expansion, less attention is given to anion type of pore space solutions. Therefore, this paper is concerned with the impact of various concentrations of different inorganic salts including NaCl, $Na_2SO_4$, and $Na_2CO_3$ on the macro and microstructure behavior of the expandable smectite clay. Comparison of the responses of the smectite/NaCl and smectite/$Na_2SO_4$ mixtures indicates that the effect of anion valance on the soil engineering properties is not very pronounced, regardless of the electrolyte concentration. However, at presence of carbonate as potential determining ions (PDIs) the swelling power increases up to 1.5 times compared to sulfate or chloride ions. The samples with $Na_2CO_3$ are also more deformable and show lower osmotic compressibility than the other mixtures. This demonstrates that the barrier performance of smectite greatly decreases in case of anions with the non-specific adsorption (e.g., $Cl^-$ and $SO{_4}^{2-}$) as the salinity of solution increases. Based on the results of the X-ray diffraction and sedimentation tests, the high soil volumetric changes upon exposure to carbonate is attributed to an increase in the repulsive forces between smectite basic unit layers due to the PDI effect of $CO{_3}^{2-}$ and increasing the pH level which enhance the buffering capacity of smectite. The study concluded that the nature of anion through its influence on the re-arrangement of soil microstructure and osmotic phenomena governs the hydro-mechanical parameters of expansive clays. It seems not coinciding with the double layer theory of the Gouy-Chapman double layer model.