• 제목/요약/키워드: PCoA analysis

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MICE 생태계 분석을 위한 PCO와 이해관계자 간의 하이퍼링크 관계망 분석 (Analysis of Hyperlink Network Relationships among PCOs and Stakeholders in MICE Ecosystem )

  • 이현애;정희정;구철모;정남호
    • 경영정보학연구
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    • 제20권3호
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    • pp.1-16
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    • 2018
  • MICE 산업은 다면적 산업으로 공공부문과 민간부문에 걸쳐 다양한 이해관계자들이 존재하며, PCO(Professional Convention Organizers)들은 이러한 이해관계자들 간의 의견을 조율하는 매개적인 역할을 한다. 따라서, PCO들은 신뢰도와 인지도를 증가시키는 한편, 이해관계자들과의 협력적 네트워크를 형성 또는 강화하기 위해 자사의 웹사이트에 이해관계자들의 하이퍼링크를 게재하고 있다. 이에 본 연구는 MICE 산업을 생태계적 관점에서 이해하고자 사회관계망 분석 기법을 적용하여 PCO와 이해 관계자들 간 하이퍼링크 관계망의 구조적 특징을 분석하고, 이 네트워크 내에서 PCO의 성과와 규모에 따라 그 역할에 차이가 있는지를 파악하고자 하였다. 연구 결과, 연결정도 중심성, 아이겐벡터 중심성, 매개 중심성, 근접 중심성이 높은 PCO를 확인하였으며, 규모가 큰 PCO가 하이퍼링크 네트워크에서 더 높은 중심성을 갖고 있음을 파악하였다.

Association between prehospital i-gel insertion and PCO2 in patients with out-of-hospital cardiac arrest

  • ;;;;;;최민정
    • 대한응급의학회지
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    • 제29권6호
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    • pp.578-584
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    • 2018
  • Objective: This study examined the initial partial pressure of carbon dioxide ($PCO_2$) as a possible indicator of prehospital ventilation and its association with prehospital i-gel in out-of-hospital cardiac arrest (OHCA) patients. Methods: The demographics and arrest parameters, including i-gel insertion and initial arterial blood gas analysis, of OHCA patients who visited the emergency department were analyzed retrospectively. Linear regression analysis was performed to examine the association between i-gel insertion and the initial $PCO_2$. Results: A total of 106 patients were investigated. Fifty-six patients had prehospital i-gel insertion and 50 patients did not have a prehospital advanced airway. The initial $PCO_2$ was higher in the i-gel group than the no advanced airway group (105.2 mmHg [77.5-134.9] vs. 87.5 mmHg [56.8-115.3], P=0.03). Prehospital i-gel insertion was associated with a higher initial $PCO_2$ level (${\beta}$ coefficient, 20.3; 95% confidence interval, 2.6-37.9; P=0.03). Conclusion: Prehospital insertion of i-gel was associated with higher initial $PCO_2$ values in OHCA patients compared to no advanced airway.

Evaluating Genetic Diversity of Agaricus bisporus Accessions through Phylogenetic Analysis Using Single-Nucleotide Polymorphism (SNP) Markers

  • Oh, Youn-Lee;Choi, In-Geol;Kong, Won-Sik;Jang, Kab-Yeul;Oh, Min ji;Im, Ji-Hoon
    • Mycobiology
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    • 제49권1호
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    • pp.61-68
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    • 2021
  • Agaricus bisporus, commonly known as the button mushroom, is widely cultivated throughout the world. To breed new strains with more desirable traits and improved adaptability, diverse germplasm, including wild accessions, is a valuable genetic resource. To better understand the genetic diversity available in A. bisporus and identify previously unknown diversity within accessions, a phylogenetic analysis of 360 Agaricus spp. accessions using single-nucleotide polymorphism genotyping was performed. Genetic relationships were compared using principal coordinate analysis (PCoA) among accessions with known origins and accessions with limited collection data. The accessions clustered into four groups based on the PCoA with regard to genetic relationships. A subset of 67 strains, which comprised a core collection where repetitive and uninformative accessions were not included, clustered into 7 groups following analysis. Two of the 170 accessions with limited collection data were identified as wild germplasm. The core collection allowed for the accurate analysis of A. bisporus genetic relationships, and accessions with an unknown pedigree were effectively grouped, allowing for origin identification, by PCoA analysis in this study.

울산 무제치늪의 식생: 군락분류와 군락동태 (Vegetation of Moojechi Moor in Ulsan: Syntaxonomy and Syndynamics)

  • 김종원;김중훈
    • The Korean Journal of Ecology
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    • 제26권5호
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    • pp.281-287
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    • 2003
  • 울산 무제치습원에 대한 생태식물상(ecological flora)과 군락유형분석이 이루어졌다. 군락유형분석은 Zurich-Montpelliar의 연구방법으로 식생유형 분류와 분포적 특성, 그리고 종조성적 군락동태를 파악하기 위하여 식생자료간의 거리(유사성)와 속성에 대한 집괴분석법 및 PCoA (Principal Coordinate Analysis) 좌표결정법이 적용되었다. 주요 감시종 13종을 포함한 습지성 식물종 49종과 중간습원 식물군락을 포함한 6개의 식물군락이 분류되었다. 식생유형은 쇠털골-좀고추나물군락, 바늘골-끈끈이주걱군락, 진퍼리새-하늘산제비난군집(신칭), 오리나무-진퍼리새군락, 소나무-억새군락, 졸참나무-은방울꽃군락 등이 기재되었으며, 동북아 산지성이탄습지의 중간습원을 대표하는 식생으로 진퍼리새군강이 새롭게 제창되었다. PCoA는 무제치습원 속에 현존하는 식물군락간의 종조성적 상이성이 토양의 수분구배와 식물군락의 층구조(생체량)에 대응하는 네 개의 천이식생형(쇠풀골형, 진퍼리새형, 억새형, 삼림형)으로 구분하였으며, 건생의 타생천이계열과 습생의 자생천이계열이 존재하고 있음이 밝혀졌다. 중간습원으로서 무제치습원에 대한 식생의 종조성과 분포의 지속성은 토사 및 영양염류의 비정상적 유입을 방지하는 습원생태계의 수문체제와 토지조건의 적극적인 고려로부터 가능하다는 것을 밝혔다.

DNA Array Analysis of Changes in Gene Expression Profile in DHEA-induced PCO

  • Yu, Jeong-Min;Yoo, Seong-Jin;Kim, Do-Rim;Youm, Mi-Young, Kim, Jee-Yun;Kang, Sung-Goo
    • 한국수정란이식학회:학술대회논문집
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    • 한국수정란이식학회 2002년도 국제심포지엄
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    • pp.112-112
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    • 2002
  • Under normal conditions, women produce a single dominant follicle that participates in a single ovuation each menstrual cycle. But Polycystic ovary syndrome(PCOS) conditions, folliculogenesis does not proceed normally. This condition leads to the accumlation of large numbers of small graffian follicles in which the theca interstitial cells (TIC) produce abnormally large amounts of androgen. PCOS is probably the most common endocrine disorder, affecting women of reprodutive age with 5-10% prevalence estimate. Chronic anovulation, hyperandrogenism, hirsutism, obesity, infertility and polycystic ovaries are clinical hallmarks of women with PCOS. Its etiology remains unknown. To investigate the gene expression pattern of ovary in PCO-induced rat, we used cDNA expression analysis. Total RNA was extracted from the ovary of PCO-induced rat and reverse-transcribed in the presence of[$\alpha$$^{32}$P]-dATP Which were hybridized to Atlas$^{TM}$ Rat Toxicology 1.2 array (Clontech) representing approximately 1176 rat genes. We compared gene expression between ovary of pco-induced immature female rats and control. Differential gene expression profiles were revealed (LIFR-alpha, ADRA1A, Heat shock 90-kDa protein A, PDGFRA). Reverse transcription-polymerase chain reaction(RT-PCR) was used to validate the relative expression pattern obtained by the cDNA array. The precise relationship between the altered expression of genes and PCO is a matter of further investigation. This study was supported by Korea Science and Engineering Foundation(KOSEF)

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Morphological characterization of Korean and Turkish watermelon germplasm

  • Huh, Yun Chan;Choi, Hak Soon;Solmaz, Ilknur;Sari, Nebahat;Kim, Su
    • 농업과학연구
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    • 제41권4호
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    • pp.309-314
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    • 2014
  • A total of 67 watermelon accessions which include 37 accessions from Korean and 27 accessions from Turkish germplasm and 3 accessions of other related species from USA were investigated for morphological characteristics. The UPOV descriptor list for 56 characters (6 seedlings, 4 plants, 11 leaves, 5 flowers, 23 fruits and 7 seeds) was used in characterization. In addition, eight quantitative characters, hypocotyl length, cotyledon width, cotyledon length, fruit weight, fruit length, fruit width, thickness of outer layer of pericarp and soluble solid content were also measured. The 56 qualitatively scored characters were analyzed by principle coordinate analysis (PCoA) while the eight quantitative ones were subjected to principle component analysis (PCA). Morphological characterization result demonstrated that the accessions displayed high morphological diversity(how much percent?). A high level of phenotypic diversity was observed from the results of morphological characterization. However, plant growth habit and leaf blade flecking showed constant characters for all of the accessions. The Korean and Turkish watermelon genotypes are diverse groups and can be separated by both multivariate analysis of morphological characters although the grouping was more apparent in PCoS results.

경북대학교 내에 생육하는 애기자운(Amblyotropis verna) 자생지의 식생특성과 관리방안에 관한 연구 (A Study on Vegetation Characteristics and Management of Amblyotropis verna Habitats in Kyungpook National University)

  • 박인환;조광진;이혜영;장갑수
    • 한국환경복원기술학회지
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    • 제13권5호
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    • pp.51-58
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    • 2010
  • This study was done to recommend a method for conserving the habitat of Amblyotropis verna grown naturally in campus of the Kyungpook National University at Daegu city. Vegetation characteristics and morphological characteristics of each individual were analyzed for the condition of the population at the growing season from May to June in 2010. Totally 11 vegetation data were collected and analyzed, and one vegetation community including Amblyotropis verna (Amblyotropis verna-Zoysia japonica community) was found. We found that the growing condition was not good with severe stamping and disturbance. The location-determining method by PCoA analysis showed the physical texture in soil was a critical factor determining the spatial distribution of the Amblyotropis verna-Zoysia japonica community. And the analysis of morphological characteristics found that light condition and soil hardness were the main ecological factor determining the size and form of each individual. Finally, this study recommend that minimizing impacts by human stamping and artificial disturbance and reducing the water stress were the best ways for the conservation of Amblyotropis verna habitats.

Ovarian volume is more closely related to the different manifestations of polycystic ovary syndrome than follicle number per ovary

  • Shazia Afrine;Jasmine Ara Haque;Md Shahed Morshed;Hurjahan Banu;Ahmed Hossain;Muhammad Abul Hasanat
    • Clinical and Experimental Reproductive Medicine
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    • 제50권3호
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    • pp.200-205
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    • 2023
  • Objective: Polycystic ovary (PCO), a diagnostic component of polycystic ovary syndrome (PCOS), requires either an ovarian volume (OV) criterion or a follicle number per ovary (FNPO) criterion. This study investigated the association of OV and FNPO criteria with various manifestations of PCOS. Methods: This cross-sectional study was conducted at a university hospital among 100 patients newly diagnosed with PCOS (according to the revised Rotterdam criteria). Fasting blood samples were collected to measure glucose, total testosterone (TT), luteinizing hormone (LH), follicle-stimulating hormone (FSH), lipid, insulin, and hemoglobin A1c levels. An oral glucose tolerance test was performed. Transabdominal or transvaginal ultrasound of the ovaries was done, depending on patients' marital status. All investigations were conducted in the follicular phase of the menstrual cycle. OV >10 mL and/or FNPO ≥12 indicated PCO. A homeostasis model assessment of insulin resistance (IR) value ≥2.6 indicated IR, and metabolic syndrome (MS) was defined according to the international harmonization criteria. Results: Seventy-six participants fulfilled the OV criterion, 70 fulfilled the FNPO criterion, and 89 overall had PCO. Both maximum OV and mean OV had a significant correlation with TT levels (r=0.239, p=0.017 and r=0.280, p=0.005, respectively) and the LH/FSH ratio (r=0.212, p=0.034 and r=0.200, p=0.047, respectively). Mean OV also had a significant correlation with fasting insulin levels (r=0.210, p=0.036). Multivariate binary logistic regression analysis showed that IR (odds ratio [OR], 9.429; 95% confidence interval [CI], 1.701 to 52.271; p=0.010) and MS (OR, 7.952; 95% CI, 1.821 to 34.731; p=0.006) had significant predictive associations with OV alone, even after adjustment for age and body mass index. Conclusion: OV may be more closely related to the androgenic and metabolic characteristics of PCOS than FNPO.

Genetic diversity of Indonesian cattle breeds based on microsatellite markers

  • Agung, Paskah Partogi;Saputra, Ferdy;Zein, Moch Syamsul Arifin;Wulandari, Ari Sulistyo;Putra, Widya Pintaka Bayu;Said, Syahruddin;Jakaria, Jakaria
    • Asian-Australasian Journal of Animal Sciences
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    • 제32권4호
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    • pp.467-476
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    • 2019
  • Objective: This research was conducted to study the genetic diversity in several Indonesian cattle breeds using microsatellite markers to classify the Indonesian cattle breeds. Methods: A total of 229 DNA samples from of 10 cattle breeds were used in this study. The polymerase chain reaction process was conducted using 12 labeled primers. The size of allele was generated using the multiplex DNA fragment analysis. The POPGEN and CERVUS programs were used to obtain the observed number of alleles, effective number of alleles, observed heterozygosity value, expected heterozygosity value, allele frequency, genetic differentiation, the global heterozygote deficit among breeds, and the heterozygote deficit within the breed, gene flow, Hardy-Weinberg equilibrium, and polymorphism information content values. The MEGA program was used to generate a dendrogram that illustrates the relationship among cattle population. Bayesian clustering assignments were analyzed using STRUCTURE program. The GENETIX program was used to perform the correspondence factorial analysis (CFA). The GENALEX program was used to perform the principal coordinates analysis (PCoA) and analysis of molecular variance. The principal component analysis (PCA) was performed using adegenet package of R program. Results: A total of 862 alleles were detected in this study. The INRA23 allele 205 is a specific allele candidate for the Sumba Ongole cattle, while the allele 219 is a specific allele candidate for Ongole Grade. This study revealed a very close genetic relationship between the Ongole Grade and Sumba Ongole cattle and between the Madura and Pasundan cattle. The results from the CFA, PCoA, and PCA analysis in this study provide scientific evidence regarding the genetic relationship between Banteng and Bali cattle. According to the genetic relationship, the Pesisir cattle were classified as Bos indicus cattle. Conclusion: All identified alleles in this study were able to classify the cattle population into three clusters i.e. Bos taurus cluster (Simmental Purebred, Simmental Crossbred, and Holstein Friesian cattle); Bos indicus cluster (Sumba Ongole, Ongole Grade, Madura, Pasundan, and Pesisir cattle); and Bos javanicus cluster (Banteng and Bali cattle).

Waterston 수술이 Gas 값과 폐조직에 미치는 영향 (Blood Gas Analysis and Lung Histopathology in Waterston Operation)

  • 김세화;이홍균
    • Journal of Chest Surgery
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    • 제5권2호
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    • pp.87-96
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    • 1972
  • Studies of blood gas and lung histopathology were done in 10 dogs after intrapericardlal aorto-right pulmonary arterial anastomosis with proximal ligation of the right pulmonary antery. Among the 5 expired during or after operation, in 3 cases, the causes of the death were due to surgical bleeding and, in 2 cases, acute cardiopulmonary insufficiency because of large anastomosis stoma measured respectively 7mm and 10mm. In the 5 of survivals, one was sacrificed because of empyema at postoperative 7 days and 2 were at postoperative one month and remained 2 at postoperative 3 month respectively. The following observations were made. 1.In every survival, continuous machinary murmur was auscultated and the angiograms of all long term survivals showed the good patency of the anastomosis stoma. 2.After the ligation of the right pulmonary artery, the values of $PO_2$ and $PCO_2$ in arterial and venous blood were generally decreased comparing with the preoperative values. The mean value of $P_aO_2$ noted $83.30{pm}11.875$[p<0.01]. After the shunts operation with ligation of the right pulmonary artery, the immediate values of PH, $PO_2$ and $PCO_2$showed no significant changes comparing with that of right pulmonary artery ligation only. In the cases of survivals more than one month, the values of $PO_2$ and $PCO_2$ in the arterial and venous blood were generally higher than that of ligation of the right pulmonary artery only. The $P_aO_2$ value noted $103.750{pm}7.395$[p<0.01]. The mean values of $P_aO_2$, $PCO_2$ and PH in the arterial and venous blood almost returned to that of preoperative studies. 3.In the specimens of lung from the cadavors expired due to acute cardiopulmonary insufficiency after the operation, there were massive congestion, hemorrhage in the alveolar spaces and bronchioles. In specimens obtained at postoperative one month, there were dilatation of alveolar spaces with partial rupture, slight congestion, and alveolar wall thickening in the lung parenchyme, but there was no significant changes in pulmonary vasculature except dilation of pulmonary capillaries. In the specimens obtained at postoperative three months, the alveolar walls were more thickened in the lung parenchyme than the finding of the specimens obtained at postoperative one month. In the wall of pulmonary capillaries, there was only slight thickening with connective tissue proliferatlon.

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