• Title/Summary/Keyword: PCoA

Search Result 150, Processing Time 0.024 seconds

True Posterior Communicating Artery Aneurysms with High Risk of Rupture despite Very Small Diameter

  • Shin, Dong Gyu;Park, Jaechan;Kim, Myungsoo;Kim, Byoung-Joon;Shin, Im Hee
    • Journal of Korean Neurosurgical Society
    • /
    • v.65 no.2
    • /
    • pp.215-223
    • /
    • 2022
  • Objective : This retrospective study investigated the clinical and angiographic characteristics of ruptured true posterior communicating artery (PCoA) aneurysms in comparison with junctional PCoA aneurysms presenting with a subarachnoid hemorrhage. Methods : The medical records and radiological data of 93 consecutive patients who underwent three-dimensional rotational angiography and surgical or endovascular treatment for a ruptured junctional or true PCoA aneurysm over an 8-year period were examined. Results : The maximum diameter of the ruptured true PCoA aneurysm (n=13, 14.0%) was significantly smaller than that of the ruptured junctional PCoA aneurysms (n=80, 4.45±1.44 vs. 7.68±3.36 mm, p=0.001). In particular, the incidence of very small aneurysms <4 mm was 46.2% (six of 13 patients) in the ruptured true PCoA aneurysm group, yet only 2.5% (two of 80 patients) in the ruptured junctional PCoA aneurysm group. Meanwhile, the diameter of the PCoA was significantly larger in the true PCoA aneurysm group than that in the junctional PCoA aneurysm group (1.90±0.57 vs. 1.15±0.49 mm, p<0.001). In addition, the ipsilateral PCoA/P1 ratio was significantly larger in the true PCoA aneurysm group than that in the group of a junctional PCoA aneurysm (mean PCoA/P1 ratio±standard deviation, 2.67±1.22 vs. 1.14±0.88; p<0.001). No between-group difference was identified for the modified Fisher grade, clinical grade at admission, and 3-month modified Rankin Scale score. Conclusion : A true PCoA aneurysm was found to be associated with a larger PCoA and ruptured at a smaller diameter than a junctional PCoA aneurysm. In particular, the incidence of a ruptured aneurysm with a very small diameter <4 mm was significantly higher among the patients with a true PCoA aneurysm.

Photocatalytic Destruction of Chlorinated and Aromatic Hydrocarbons for Low-Level Indoor Air Cleaning (저농도 실내공기 정화를 위한 염소화 및 방향족 탄화수소의 광촉매 분해)

  • Jo, Wan Geun;Gwon, Gi Dong;Choe, Sang Jun;Song, Dong Ik
    • Journal of Environmental Science International
    • /
    • v.13 no.9
    • /
    • pp.767-777
    • /
    • 2004
  • This study evaluated the technical feasibility of the application of $TiO_2$ photocatalysis for the removal of volatile hydrocarbons(VHC) at low ppb concentrations commonly associated with non-occupational indoor air quality issues. A series of experiments was conducted to evaluate five parameters (relative humidity (RH), hydraulic diameter (HD), feeding type (FT) of VHC, photocatalytic oxidation (PCO) reactor material (RM), and inlet port size (IPS) of PCO reactor) for the PCO destruction efficiencies of the selected target VHC. None of the target VHC presented significant dependence on the RH, which are inconsistent with a certain previous study that reported that under conditions of low humidity and a ppm toluene inlet level, there was a drop in the PCO efficiency with decreasing humidity. However, it is noted that the four parameters (HD, RM, FT and IPS) should be considered for better VHC removal efficiencies for the application of $TiO_2$ photocatalytic technology for cleansing non-occupational indoor air. The PCO destruction of VHC at concentrations associated with non-occupational indoor air quality issues can be up to nearly 100%. The amount of CO generated during PCO were a negligible addition to the indoor CO levels. These abilities can make the PCO reactor an important tool in the effort to improve non-occupational indoor air quality.

Analysis of Hyperlink Network Relationships among PCOs and Stakeholders in MICE Ecosystem (MICE 생태계 분석을 위한 PCO와 이해관계자 간의 하이퍼링크 관계망 분석)

  • Hyunae Lee;Heechung Chung;Chulmo Koo;Namho Chung
    • Information Systems Review
    • /
    • v.20 no.3
    • /
    • pp.1-16
    • /
    • 2018
  • MICE (Meetings, Incentive trip, Convention and Exhibition & Event) industry is a multifaceted industry with a variety of stakeholders including the public and private sectors, and PCOs (Professional Convention Organizers) play a mediating role in communicating opinions of the stakeholders. For enhancing their reliability and awareness, PCOs have their stakeholders' hyperlinks on the websites. This study attempted to analyze the hyperlink networks among PCOs (Professional Convention Organizers) and their stakeholders so as to understand the MICE industry ecosystem and find out whether the network structure of PCOs' shows different levels of hyperlink use with their stakeholders' websites based upon PCO's performance and size. The results showed the hyperlink network of MICE industry and that the bigger PCOs have higher centralities in the network.

A Fast Converging Pulse Coupling Oscillator Synchronicity Model

  • Yu, Niu;d'Auriol, Brian J.;Lee, Sung-Young;Lee, Young-Koo
    • Proceedings of the Korea Information Processing Society Conference
    • /
    • 2007.05a
    • /
    • pp.860-861
    • /
    • 2007
  • The Pulse Coupling Oscillator (PCO) is a synchronicity model inspired by nature. However, the PCO model has some limitations. The Fast PCO model is proposed in this paper. It addresses the problem of the phase swing actions in the original PCO model. Benefits are the fast synchronicity speed and associated energy saving.

  • PDF

Ideal Internal Carotid Artery Trapping Technique without Bypass in a Patient with Insufficient Collateral Flow

  • Chung, Joon-Ho;Shin, Yong-Sam;Lim, Yong-Cheol;Park, Min-Jung
    • Journal of Korean Neurosurgical Society
    • /
    • v.45 no.4
    • /
    • pp.260-263
    • /
    • 2009
  • Internal carotid artery (ICA) trapping can be used for treating intracranial giant aneurysm, blood blister-like aneurysms and ICA rupture during the surgery. We present a novel ICA trapping technique which can be used with insufficient collaterals flow via anterior communicating artery (AcoA) and posterior communicating artery (PcoA). A patient was admitted with severe headache and the cerebral angiography demonstrated a typical blood blister-like aneurysm at the contralateral side of PcoA. For trapping the aneurysm, the first clip was placed at the ICA just proximal to the aneurysm whereas the distal clip was placed obliquely proximal to the origin of the PcoA to preserve blood flow from the PcoA to the distal ICA. The patient was completely recovered with good collaterals filling to the right ICA territories via AcoA and PcoA. This technique may be an effective treatment option for trapping the aneurysm, especially when the PcoA preservation is mandatory.

Photocatalytic Oxidation of Indoor Air Volatile Organic Compounds (VOCs) in pub Level

  • Jo, Wan-Kuen;Kim, Dong-Hyun;Ki, Jae-Chang;Huh, Jeung-Soo
    • Journal of Korean Society for Atmospheric Environment
    • /
    • v.19 no.E4
    • /
    • pp.157-168
    • /
    • 2003
  • This study evaluated the technical feasibility of the application of titanium oxide (TiO$_2$) photocatalysis for the removal of VOCs in low ppb concentrations commonly associated with non -occupational indoor air quality issues. A series of experiments were conducted to evaluate four parameters (relative humidity (RH), hydraulic diameter (HD), photocatalytic oxidation (PCO) reactor material (RM), and inlet port size (IPS) of PCO reactor) for the PCO destruction efficiencies of the selected target VOCs. None of the target VOCs presented significant dependency on the RH, which is inconsistent with a few previous studies. However, it is noted that the three parameters (HD, RM and IPS) should be considered for better VOCs removal efficiencies for the application of TiO$_2$ photocatalytic technology for cleansing non -occupational indoor air. The PCO destruction of VOCs at concentrations associated with non-occupational indoor air quality issues can be up to nearly 100%. The amount of CO generated during PCO would be negligible in comparison to the indoor CO levels. These results can make the PCO reactor an important tool in the effort to improve non-occupational indoor air quality.

Increased Serum Level of Inhibin in Oligo-amenorrheic Women with Polycystic Ovaries (배란장애를 동반한 다낭성 난소인 여성에서 혈중 Inhibin 농도의 증가)

  • Roh, Jae-Sook;Yoo, Jung-Bae;Moon, Hyung;Hwang, Yoon-Yeong
    • Clinical and Experimental Reproductive Medicine
    • /
    • v.25 no.1
    • /
    • pp.93-102
    • /
    • 1998
  • Normal and abnormal follicular growth and steroidogenesis depend on gonadotropins as well as intraovarian peptides, which may mediate or potentiate gonadotropin action. Inhibin also affect follicular development and steroidogenesis and may play a role in dominant follicle selection and follicular atresia. Therefore, we studied the differences of serum inhibin, gonadotropin and androgen levels in the women with only the ultrasound findings and no disorder, and polycystic ovary (PCO) with ovulatory disturbance. We prospectively analysed forty-three women with PCO. The diagnosis of PCO was based on typical appearance of the ovaries on TVS. Twelve women with regular menstrual cycle and normal ovarian morphology were selected as control. Basal levels of inhibin, luteinizing hormone (LH), follicle stimulating hormone (FSH), estradiol $(E_2)$, testosterone (T), androstenedione (ADD), dehydroepiandrosterone-sulfate (DS), prolactin and TSH in serum were determined. There were significant differences in basal LH levels and LH/FSH ratio between the control and the women with PCO. The basal levels of inhibin and $E_2$ in the oligo-amenorrheic PCO (N=34) were significantly higher than those in the control. There was higher negative correlation between the inhibin and T levels in the oligo-amenorrheic PCO, but, not in the regular cycling PCO. Also, there was higher positive correlation between the LH and T levels in the oligo-amenorrheic PCO, but not in the regular cycling PCO. These data presume that the initial event of PCO is elevated pituitary LH secretion. Elevated levels of LH may down-regulate LH receptors on granulosa cells and also cause hypertrophy of the thecal layer. High level of androgen secreted by the hypertrophied thecal layer may stimulate inhibin secretion from granulosa cells and can be converted to estrogen by extraovarian tissues and could serve to augment pituitary sensitivity to GnRH with a resultant secretion of more LH than FSH. Inhibin may inhibit FSH action on granulosa cell in the PCO follicle, impairing follicular development and dominant follicle selection resulted in ovulatory disturbance.

  • PDF

The Usefulness of Extradural Anterior Clinoidectomy for Low-Lying Posterior Communicating Artery Aneurysms : A Cadaveric Study

  • Hyoung Soo Byoun;Kyu-Sun Choi;Min Kyun Na;Sae Min Kwon;Yong Seok Nam
    • Journal of Korean Neurosurgical Society
    • /
    • v.67 no.4
    • /
    • pp.411-417
    • /
    • 2024
  • Objective : To confirm the usefulness of the extradural anterior clinoidectomy during the clipping of a low riding posterior communicating artery (PCoA) aneurysm through cadaver dissection. Methods : Anatomic measurements of 12 adult cadaveric heads (24 sides total) were performed to compare the microsurgical exposure of the PCoA and internal carotid artery (ICA) before and after clinoidectomy. A standard pterional craniotomy and transsylvian approach were performed in all cadavers. The distance from the ICA bifurcation to the origin of PCoA (D1), pre-anterior clinoidectomy distance from the ICA bifurcation to tentorium (D2), post-anterior clinoidectomy distance from the ICA bifurcation to tentorium (D3), pre-anterior clinoidectomy distance from the tentorium to the origin of PCoA (D4) and post-anterior clinoidectomy distance from the tentorium to the origin of PCoA (D5) and the distance of the ICA obtained after anterior clinoidectomy (D6) were measured. We measured the precise thickness of the blade for the Yasargil clip with a digital precision ruler to confirm the usefulness of the extradural anterior clinoidectomy. Results : Twenty-four sites were dissected from 12 cadavers. The age of the cadavers was 79.83±6.25 years. The number of males was the same as the females. The space from the proximal origin of the PCoA to the preclinoid-tentorium (D4) was 1.45±1.08 mm (max, 4.01; min, 0.56). After the clinoidectomy, the space from the proximal origin of the PCoA to the postclinoid-tentorium (D5) was 3.612±1.15 mm (max, 6.14; min, 1.83). The length (D6) of the exposed proximal ICA after the extradural clinoididectomy was 2.17±1.04 mm on the lateral side and 2.16±0.89 mm on the medial side. The thickness of the Yasargil clip blade used during the clipping surgery was 1.35 mm measured with a digital precision ruler. Conclusion : The proximal length obtained by performing an external anterior clinoidectomy is about 2 mm, sufficient for proximal control during PCoA aneurysm surgery, considering the thickness of the aneurysm clips. In a subarachnoid hemorrhage, performing an extradural anterior clinoidectomy could prevent a devastating situation during PCoA aneurysm clipping.

Alteration of TGFB1, GDF9, and BMPR2 gene expression in preantral follicles of an estradiol valerate-induced polycystic ovary mouse model can lead to anovulation, polycystic morphology, obesity, and absence of hyperandrogenism

  • Asghari, Reza;Shokri-Asl, Vahid;Rezaei, Hanieh;Tavallaie, Mahmood;Khafaei, Mostafa;Abdolmaleki, Amir;Seghinsara, Abbas Majdi
    • Clinical and Experimental Reproductive Medicine
    • /
    • v.48 no.3
    • /
    • pp.245-254
    • /
    • 2021
  • Objective: In humans, polycystic ovary syndrome (PCOS) is an androgen-dependent ovarian disorder. Aberrant gene expression in folliculogenesis can arrest the transition of preantral to antral follicles, leading to PCOS. We explored the possible role of altered gene expression in preantral follicles of estradiol valerate (EV) induced polycystic ovaries (PCO) in a mouse model. Methods: Twenty female balb/c mice (8 weeks, 20.0±1.5 g) were grouped into control and PCO groups. PCO was induced by intramuscular EV injection. After 8 weeks, the animals were killed by cervical dislocation. Blood serum (for hormonal assessments using the enzyme-linked immunosorbent assay technique) was aspirated, and ovaries (the right ovary for histological examinations and the left for quantitative real-time polymerase) were dissected. Results: Compared to the control group, the PCO group showed significantly lower values for the mean body weight, number of preantral and antral follicles, serum levels of estradiol, luteinizing hormone, testosterone, and follicle-stimulating hormone, and gene expression of TGFB1, GDF9 and BMPR2 (p<0.05). Serum progesterone levels were significantly higher in the PCO animals than in the control group (p<0.05). No significant between-group differences (p>0.05) were found in BMP6 or BMP15 expression. Conclusion: In animals with EV-induced PCO, the preantral follicles did not develop into antral follicles. In this mouse model, the gene expression of TGFB1, GDF9, and BMPR2 was lower in preantral follicles, which is probably related to the pathologic conditions of PCO. Hypoandrogenism was also detected in this EV-induced murine PCO model.

GNSS Antenna PCO/PCV and Position Changes due to the Switch IGS08/igs08.atx to IGS14/igs14.atx

  • Choi, Byung-Kyu;Sohn, Dong-Hyo;Yoon, Ha-Su;Lee, Sang Jeong
    • Journal of Positioning, Navigation, and Timing
    • /
    • v.11 no.2
    • /
    • pp.83-89
    • /
    • 2022
  • For precise GNSS applications, the antenna phase center correction (PCC) is absolutely required. The PCC magnitude can reach the centimeter level with the antenna structure. In the present study, we first investigate the phase center offset (PCO) and phase center variation (PCO) of three different antenna models in two different reference frames, IGS08/igs08.atx and IGS14/igs14.atx. Clear L1 and L2 PCO differences were found between IGS08 and IGS14. In addition, the PCV showed characteristics that is dependent upon the signal direction (azimuth and elevation angle). The remarkable thing is that the changes of a Dorne Margolin choke-ring antenna model (AOAD/MT DOME) was very small in two reference frames. In order to analyze changes in positions according to different reference systems, GNSS data obtained from DAEJ, SUWN, and TSKB stations were processed by the precise point positioning (PPP) method. We suggest that an antenna PCO/PCV can affect the precise GNSS positioning on the order of several millimeters in two different reference frames.