• Korean Circulation Journal
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• 제48권11호
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• pp.989-999
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• 2018

Background and Objectives: We aimed to compare outcomes of complete revascularization (CR) versus culprit-only revascularization for ST-segment elevation myocardial infarction (STEMI) and multivessel disease (MVD) in the $2^{nd}$ generation drug-eluting stent (DES) era. Methods: From 2009 to 2014, patients with STEMI and MVD, who underwent primary percutaneous coronary intervention (PCI) using a $2^{nd}$ generation DES for culprit lesions were enrolled. CR was defined as PCI for a non-infarct-related artery during the index admission. Major adverse cardiovascular event (MACE) was defined as cardiovascular (CV) death, non-fatal myocardial infarction, target lesion revascularization, or heart failure during the follow-up year. Results: In total, 705 MVD patients were suitable for the analysis, of whom 286 (41%) underwent culprit-only PCI and 419 (59%) underwent CR during the index admission. The incidence of MACE was 11.5% in the CR group versus 18.5% in the culprit-only group (hazard ratio [HR], 0.56; 95% confidence interval [CI], 0.37-0.86; p<0.01; adjusted HR, 0.64; 95% CI, 0.40-0.99; p=0.04). The CR group revealed a significantly lower incidence of CV death (7.2% vs. 12.9%; HR, 0.51; 95% CI, 0.31-0.86; p=0.01 and adjusted HR, 0.57; 95% CI; 0.32-0.97; p=0.03, respectively). Conclusions: CR was associated with better outcomes including reductions in MACE and CV death at 1 year of follow-up compared with culprit-only PCI in the $2^{nd}$ generation DES era.

• 대한물리의학회지
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• 제14권1호
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• pp.63-73
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• 2019

PURPOSE: This study examined the effects of cardiopulmonary physiotherapy on the cardiopulmonary function, metabolism, inflammatory markers, and quality of life in patients with coronary artery disease who underwent percutaneous coronary intervention (PCI). METHODS: Electronic bibliographic databases of a regional information sharing system (RISS) and PubMed were searched to identify studies with randomized and non-randomized controlled trials. As the final outcome, 320 publications were identified and 18 studies met the inclusion and exclusion criteria. All studies were assessed for the quality of study using Cochrane's risk of bias. RESULTS: Sixteen studies met the inclusion criteria, in which meta-analysis had been conducted to examine the effectiveness of cardiopulmonary physiotherapy on the cardiopulmonary function, metabolism, inflammatory markers, and quality of life in patients undergoing PCI. Meta-analysis based on a random effect model showed that the cardiopulmonary physiotherapy was beneficial in improving the cardiopulmonary function, metabolism, inflammatory markers, and quality of life. In particular, there was a significant effect on the peak oxygen uptake (effect size 5.30%; 95% confidence interval 3.62~6.97). Cardiopulmonary physiotherapy for a during period of 6 weeks or more was effective in significantly improving the cardiopulmonary function and metabolism function in a subgroup analysis, but cardiopulmonary physiotherapy for less than 6 weeks was not effective. CONCLUSION: Cardiopulmonary physiotherapy has positive effects on the cardiopulmonary function, metabolism, inflammatory markers, and quality of life in patients undergoing PCI.

• 미생물학회지
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• 제55권2호
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• pp.112-116
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• 2019

Thp1/PCID2 단백질은 전사와 연계되어 mRNA를 핵에서 세포질로 방출하는데 필요한, 진화적으로 보존된 TREX-2 복합체의 구성요소이다. 분열효모인 Schizosaccharomyces pombe에는 Thp1/PCID2 단백질의 이종상동체가 2개 존재한다. pci2(SPBC1105.07c) 유전자 이외에, SPAC1B3.08 유전자는 PCI 영역을 갖고 있으며 TREX-2 복합체의 구성요소로 추정되는 단백질을 암호화하고 있다. SPAC1B3.08을 과발현하면, 생장이 약간 느려지고 mRNA 방출에 결함을 보였다. Yeast two-hybrid와 공동침전 분석 실험에서 SPAC1B3.08 단백질은 TREX-2 복합체의 다른 구성요소인 Sac3, Dss1 단백질들과 상호작용하였다. 이와 같은 관찰들은 S. pombe의 SPAC1B3.08 단백질도 TREX-2 복합체의 구성요소로서 mRNA 방출에 관여할 가능성을 지지한다.

• Journal of Preventive Medicine and Public Health
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• 제55권4호
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• pp.351-359
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• 2022

Objectives: The Regional CardioCerebroVascular Center (RCCVC) project was initiated to improve clinical outcomes for patients with acute myocardial infarction or stroke in non-capital areas of Korea. The purpose of this study was to evaluate the outcomes and issues identified by the Busan RCCVC project in the treatment of ST-segment elevation myocardial infarction (STEMI). Methods: Among the patients who were registered in the Korean Registry of Acute Myocardial Infarction for the RCCVC project between 2007 and 2019, those who underwent percutaneous coronary intervention (PCI) for STEMI at the Busan RCCVC were selected, and their medical data were compared with a historical cohort. Results: In total, 1161 patients were selected for the analysis. Ten years after the implementation of the Busan RCCVC project, the median door-to-balloon time was reduced from 86 (interquartile range [IQR], 64-116) to 54 (IQR, 44-61) minutes, and the median symptom-to-balloon time was reduced from 256 (IQR, 180-407) to 189 (IQR, 118-305) minutes (p<0.001). Inversely, the false-positive PCI team activation rate increased from 0.6% to 21.4% (p<0.001). However, the 1-year cardiovascular death and major adverse cardiac event rates did not change. Even after 10 years, approximately 75% of the patients had a symptom-to-balloon time over 120 minutes, and approximately 50% of the patients underwent inter-hospital transfer for primary PCI. Conclusions: A decade after the implementation of the Busan RCCVC project, although time parameters for early reperfusion therapy for STEMI improved, at the cost of an increased false-positive PCI team activation rate, survival outcomes were unchanged.

• 한국품질경영학회:학술대회논문집
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• 한국품질경영학회 1998년도 The 12th Asia Quality Management Symposium* Total Quality Management for Restoring Competitiveness
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• pp.309-315
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• 1998

Process Capability can be expressed with a process index which indicates the incapability of a process to meet its specifications. This index is regarded as a process capability index(PCI) or more precisely as a process incapability index(PII). It is obtained from a simple transformation of a PCI. Greenwich and Jahr-Schaffrath(1995) considered the PII $C_{pp}$ which could be obtained from the transformation to the PCI, $C_{pm}$, and they provided the asymptotic distribution for $C_{pp}$ which was useful unless the process characteristic was normally distributed. However, some statistical inferences based on the asymptotic distribution need a large sample size. There are some processes which process engineers could not help obtaining sufficiently a large sample size. Thus, we have derived its corresponding bootstrap asymptotic distribution since bootstrapping would be a helpful technique for the PII, $C_{pp}$ which was nonparametric or free from assumptions of the distribution of the characteristic X. Moreover, we have constructed six bootstrap confidence intervals used in reducing bias of estimations based on the bootstrap asymptotic distribution and simulated their performances for $C_{pp}$,

• 대한간호학회지
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• 제39권6호
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• pp.860-867
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• 2009

Purpose: The purpose of this study was to identify the factors that predict discomfort after coronary angiography or percutaneous coronary intervention (PCI) among hospitalized patients. Methods: A total of 203 patients who underwent coronary angiography or PCI were recruited from C hospital located in S city, J province, from June through August 2008. The level of discomfort was measured and standardized by two instruments, discomfort questionnaire and the Visual Analogue Scale (VAS). Results: Stepwise multiple regression showed that the factors predicting the level of discomfort were type of angiography, gender, previous angiography, dysuria, pre-information, and sleep satisfaction, which together explained 30.6% of the total variance of the level of discomfort. Conclusion: Patients who had previous experience with these procedures, received a pre-information about the upcoming procedure, had no dysuria, and had slept well after the procedure were less likely to complain discomfort. Pre-informed education should be given by nurses to patients who will have an angiography or PCI to reduce their physical and emotional discomforts.

• Smart Structures and Systems
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• 제19권2호
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• pp.151-161
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• 2017

A new method is developed to estimate road profile in order to estimate IRI based on the ASTM standard. This method utilizes an accelerometer and a Dynamic Tire Pressure Sensor (DTPS) to estimate road roughness. The accelerometer measures the vertical axle acceleration. The DTPS, which is mounted on the tire's valve stem, measures dynamic pressure inside the tire while driving. Calibrated transfer functions are used to estimate road profile using the signals from the two sensors. A field test was conducted on roads with different quality conditions in the city of Brockton, MA. The IRI values estimated with this new method match the actual road conditions measured with Pavement Condition Index (PCI) based on the ASTM standard, images taken from an onboard camera and passengers' perceptions. IRI has negative correlation with PCI in general since they have overlapping features. Compared to the current method of IRI measurement, the advantage of this method is that a) the cost is reduced; b) more space is saved; c) more time is saved; and d) mounting the two sensors are universally compatible to most cars and vans. Therefore, this method has the potential to provide continuous and global monitoring the health of roadways.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2011년도 제42회 하계학술대회
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• pp.766-767
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• 2011

전력 IT 추세에 따라 IED(Intelligent Electronic Device)에서 다양한 기능이 요구되고 있으며, 따라서 이를 구현하기 위한 시스템도 복잡화되어 가고 있다. 또한 IED 내부에서에서 처리하여야 하는 데이터양이 대폭 증가하고 있으며 고속의 처리 속도를 요구하고 있기 때문에 산업용 시스템 버스의 도입 필요성이 제기되고 있다. 산업용 시스템 버스는 오랜 적용기간을 통해 그 신뢰성을 검증받았으며, 호환성이 뛰어나 H/W 플랫폼으로서의 가치가 있다. IED의 경우와 같이 다수 개의 CPU가 요구되는 시스템에서 CPU간 H/W적인 데이터 인터페이스 방식을 어떻게 선정하는지는 매우 중요하며 본 논문에서는 CompactPCI 기반의 최신 기술인 CompactPCI Plus IO와 Serial 기술에 대하여 살펴보고, IED에서 사용되는 기존의 메모리 공유방식이나 저속 시리얼 방식 대신 상기 CompactPCI 기반의 기술을 적용하는 방안에 대하여 검토해 보기로 한다.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2005년도 ICCAS
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• pp.472-475
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• 2005

This paper present a robot controller developed for shipbuilding yard. Since shipbuilding process handles large work pieces and has dusty and noisy environment, the developed controller has separated architecture into main control part and servo control part. Main control part is located in control room while servo control part is located near robot with work pieces. Commutation between two parts is done through SynqNet and RS485. Air purging system is adapted to servo control part for better reliability. We aimed open architecture in both hardware and software architecture. For open hardware architecture, we employed Compact PCI (cPCI) because it is widely used bus system and very reliable. Since lots of commercial boards are available with cPCI interface, upgrade and reconfiguration is easy. For open software architecture, Windows XP�� Embedded is selected as operating system (OS), because it is very popular OS and most hardware vender supports device driver for the windows XP.

• 중환자간호학회지
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• 제9권2호
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• pp.24-35
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• 2016

Purpose: This study investigated the degree of stress, depression, mindfulness and life satisfaction of elderly patients who had undergone percutaneous coronary intervention (PCI) and identified factors influencing life satisfaction. Methods: Participants were 106 patients over 60 years who had undergone PCI in a university hospital. Results: The mean scores for stress, depression, mindfulness, and life satisfaction were $9.10{\pm}2.53$, $7.77{\pm}3.32$, $88.57{\pm}8.47$, and $17.40{\pm}5.38$ respectively. There were statistically significant differences in life satisfaction by main source of income (F = 4.74, p = .004) and perceived health status as compared with peer (F = 4.80, p = .010). Depression (p < .001) explained 38 % of the total variance of life satisfaction, and the explanatory power increased to 42 % when mindfulness (p = .035) was added. There were significant correlations among stress, depression, mindfulness and life satisfaction of the patients. Conclusions: Depression and mindfulness were significant influencing factors on subjects' satisfaction in life. To enhance the life satisfaction of the elderly patients after PCI, it is necessary to reduce depression and to develop mindfulness-based interventions.